Frequency of migraine and its associated triggers and relievers among medical students of Lahore: a cross-sectional study.

Introduction: Headache is a widely prevalent illness that negatively impacts people's lives, leaving them functionally incapable of performing regular everyday tasks. The global burden of headache is 40%, of which migraine accounts for 47%. Objective: This study aims to determine the frequency of migraine among medical students of Lahore and its characteristics, associated triggers, and relievers among medical students. Methodology: A cross-sectional study was conducted in medical colleges after obtaining ethical approval. Migraine was diagnosed using the criteria provided in the International Classification of Headache Disorders, Third Edition (ICHD-3), and data on triggers, relief, and demographics were collected. The information is analyzed using SPSS 22. Result: The data were collected from 522 medical students. The average age of the students was 21.3 ± 2.0 SD (in years). About 146 (28.0%) of the medical students have migraine according to ICHD-3 criteria and were diagnosed initially. Gender was insignificantly associated with migraine (P-value=0.32). Students with psoriasis, hypertension, and polycystic ovarian syndrome were statistically significantly related to migraines with a P-value=0.002. Dehydration is the most frequent aggravator, and adequate sleep is the most frequent reliever of migraine. Conclusion: The findings show a high frequency of migraine. They are similar in both genders, depicting that stressful lifestyles, inadequate sleep patterns, and bizarre dietary habits make them more prone to migraine episodes. So, further, detailed studies should be done on evaluating triggers and relievers of migraine and their interrelations with migraine so we can focus on preventive strategies, diagnosis, and treatment of migraine.

A Cross-Sectional Survey of Knowledge, Attitude, and Practices (KAP) Toward Pandemic COVID-19 Among the General Population of Jammu and Kashmir, India.

Awareness and comprehension of disease origin, transmission, and control in a health crisis are mainly affected by the knowledge, attitude, and practices (KAP) of the general public. We conducted the current study to assess KAP among the general population of Jammu and Kashmir (J&K), India, based on an online cross-sectional survey. Participants completed a questionnaire we developed consisting of KAP questions. We also collected sociodemographic information and source of information about disease awareness. The main source of information regarding COVID-19 was Internet social media (66.3%) followed by TV (17.4%). We conducted nonparametric analyses on KAP scores using a Mann-Whitney U and Kruskall-Wallis H tests (P < .05) to find out the association with sociodemographic characteristics. The overall knowledge score (correct answer) was 88.9%, which was significantly associated with gender, age, qualification, and occupation. The positive attitude score was 73.3%, which was significantly associated with gender, age, qualification, marital status, and geographic area. Overall, 93.0% positive practices were observed in the general population based on asked questions. These scores were significantly associated with gender, age, qualification, marital status, area, and occupation. On the basis of the Spearmen correlation test (P < .01), a significant correlation was observed between scores of knowledge and attitude, with rs = +0.28, P = .000, knowledge and practices scores as rs = +0.24, P = .000, and attitude and practices scores as rs = +0.24, P = .000. However, due to the limited sample presentation in the survey, the study is unable to generalize to lower socioeconomic communities.

Antibacterial activity of Pakistani Beri honey compared with silver sulfadiazine on infected wounds: a clinical trial.

OBJECTIVE: To determine the antibacterial activity of Pakistani Beri honey in patients with infected wounds in comparison with silver sulfadiazine. METHOD: Inpatients with infected wounds at a tertiary care hospital were divided in to three equal-sized treatment groups. In Group A, patients were treated with non-Gamma irradiated Beri honey. In Group B, Gamma irradiated Beri honey was used, and in Group C silver sulfadiazine was used. Treatment was for a period of four weeks. Pus swabs were taken at day zero and weeks one and four of treatment. Bacteria were identified using the analytical profile index system API 20E, 20NE and API Staph and antimicrobial susceptibility was done as per the Clinical and Laboratory Standards Institute 2010 guidelines. RESULTS: A total of 90 patients with wounds (n=90) took part in the trial. Out of 90 wounds, 47% were post-traumatic and 37% were postoperative. Overall, average length, width and depth of Group A patients' wounds were significantly reduced (p<0.0001). Out of 144 pus swabs; 99 and 45 were Gram-negative rods and Gram-positive cocci, respectively. Among these Pseudomonas aeruginosa (n=25) and Staphylococcus aureus (n=38) were the major pathogens. Interestingly, bacterial load gradually decreased from baseline to week four due to non-Gamma irradiated Beri honey. Moreover, both the Gram-negative rods and Gram-positive cocci displayed 100% resistance to commonly used antibiotics; the most effective drugs were carbapenem and vancomycin. CONCLUSION: Pakistani Beri honey could be used as an alternative therapeutic option for the management of infected wounds.