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The physiological systems and biological applications that have arisen during the past 15 years depend heavily on the microscale and nanoscale fluxes. Microchannels have been utilized to develop new diagnostic assays, examine cell adhesion and molecular transport, and replicate the fluid flow microenvironment of the circulatory system. The various uses of MHD boundary flow in engineering and technology are extensive, ranging from MHD power generators and the polymer industry to MHD flow meters and pumps and the spinning of filaments. In this investigation, the (Magnetohydrodynamic) MHD flow of Prandtl nanofluid is investigated along with mixed convection, energy activation, microorganism, and chemical reaction. The flow model is considered through partial differential equations in dimensionless form which is then integrated numerically via considering the Bvp4c technique. The outcome is numerous emerging physical parameters over velocity profile, temperature, mass concentration, and microorganism with the separate pertinent quantities such as the Prandtl fluid parameter, elastic fluid parameter, magnetic field, mixed convection parameter, activation energy, chemical reaction, Brownian motion, thermophoretic force, Prandtl number, and Schmidt number. The friction factor, rate of heat transfer and Sherwood number, and density of microbes are revealed numerically and graphically. The outcomes indicate that the Prandtl fluid parameter and elastic fluid parameter tend to enhance the velocity profile. It is also noted that the Prandtl fluid parameter depreciates the thermal rate with the addition of the concentration profile while the opposite trend is recorded for activation energy. Obtained numerical outcomes are correspondingly compared with the current statistics in limiting cases and a close match is obtained.
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In comparison to Newtonian fluids, non-Newtonian fluids have fascinating features in heat transportation. Here, newly type of Reiner-Rivlinnanoliquid flow over the revolving disk for viscous dissipation (VD) is being explored in a multiple-slip effect. The inclusion of gyrotactic microorganisms in the nanoliquid enhances the tendency of the nanoparticles. The idea of the intended model is enhanced by considering in the impact of activation energy, thermal radiative, heated convective conditions and entropy minimization. The system of nonlinear PDE is constructed into nonlinear ODE's by applying the von-Karman similarity method and later solved numerically using the BVP4c solver which is considered to study the complicated ordinary differential equations. TheInfluence of various parameters is elaborated and plotted physically through the graphical illustration. By contrasting the reported data in the restricted form to a previously published article, the accuracy of the current model has examined. The impact of a non-Newtonian fluid parameter over the velocity field appeared to showdpreciation in it. The results elucidate that when the wall slip coefficient is larger more torque is needed to maintain constant disk revaluation. Surface heat transmission and wall skin friction are computed for a wide variety of factors. These flows have several real world-applications, including modeling cases that occur in oceanography and geophysics, various industrial fields (such as lumber production).
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The impact of chemical reaction and activation energy plays a vital role in the analysis of fluid dynamics and its thermal properties. The application of the flow of fluid is significantly considered in nuclear reactors, automobiles, manufacturing setups, electronic appliances etc. This study explores the impacts of activation energy and chemical reaction on the magnetohydrodynamic Darcy-Forchheimer squeezed Casson fluid flow through a porous material across the horizontal channel where the two parallel plates are assumed to be in motion. By using similarity variables, partial differential equations are converted to ordinary differential equations. Numerical method is applied using MATLAB to solve the problems and acquire the data for velocity field, thermal distribution, and concentration distribution. The graphs indicate that fluid velocity and temperature increases as the plates are brought closer. In addition, there was a correlation between a rise in the Hartmann number and a decrease in the fluid's velocity because of the existence of strong Lorentz forces. The temperature and the concentration of the liquid will increase due to the Brownian motion. When the Darcy-Forchheimer and activation energy parameters are both increased, the velocity and concentration decreases.
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The intention of this study is to carry out a numerical investigation of time-dependent magneto-hydro-dynamics (MHD) Eyring-Powell liquid by taking a moving/static wedge with Darcy-Forchheimer relation. Thermal radiation was taken into account for upcoming solar radiation, and the idea of bioconvection is also considered for regulating the unsystematic exertion of floating nanoparticles. The novel idea of this work was to stabilized nanoparticles through the bioconvection phenomena. Brownian motion and thermophoresis effects are combined in the most current revision of the nanofluid model. Fluid viscosity and thermal conductivity that depend on temperature are predominant. The extremely nonlinear system of equations comprising partial differential equations (PDEs) with the boundary conditions are converted into ordinary differential equations (ODEs) through an appropriate suitable approach. The reformed equations are then operated numerically with the use of the well-known Lobatto IIIa formula. The variations of different variables on velocity, concentration, temperature and motile microorganism graphs are discussed as well as force friction, the Nusselt, Sherwood, and the motile density organism numbers. It is observed that Forchheimer number Fr decline the velocity field in the case of static and moving wedge. Furthermore, the motile density profiles are deprecated by higher values of the bio convective Lewis number and Peclet number. Current results have been related to the literature indicated aforementioned and are found to be great achievement.
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In this article, a Riga plate is exhibited with an electric magnetization actuator consisting of permanent magnets and electrodes assembled alternatively. This Riga plate creates an electric and magnetic field, where a transverse Lorentz force is generated that contributes to the flow along the plate. A new study field has been created by Sutterby nanofluid flows down the Riga plate, which is crucial to the creation of several industrial advancements, including thermal nuclear reactors, flow metres, and nuclear reactor design. This article addresses the second law analysis of MHD Sutter by nanofluid over a stretching sheet with the Riga plate. The Cattaneo-Christov Double Diffusion heat and mass flux have been created to examine the behaviour of relaxation time. The bioconvection of motile microorganisms and chemical reactions are taken into consideration. Similarity transformations are used to make the governing equations non-dimensional ordinary differential equations (ODE's) that are subsequently solved through an efficient and powerful analytic technique, the homotopy analysis method (HAM). The effect of pertained variables on velocity, temperature, concentration, and motile microorganism distributions are elaborated through the plot in detail. Further, the velocity distribution enhances and reduces for greater value Deborah number and Reynold number for the two cases of pseudoplastic and dilatant flow. Microorganism distribution decreases with the augmented magnitude of Peclet number (Pe), Bioconvection Lewis number (Lb), and microorganism concentration difference number (Ï). The entropy production distribution is increased for the greater estimations of the Reynolds number (ReL) and Brinkman parameter (Br). Two sets of graphical outputs are presented for the Sutterby fluid parameter. Finally, for the justification of these outcomes, tables of comparison are made with various variables.
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Hybrid nanofluids containing titanium alloy particles have a large class of applications in industrial plastics and soaps, microsensors, aerospace material designs, optical filters, nanowires, surgical implants, and a variety of biological applications. This paper presents a mathematical analysis of Soret and Dufour impacts on the radiative flow through a thin moving needle of binary hybrid alloys nanoparticles. The transformed ordinary differential equations are solved numerically using the built-in function, bvp4c, in MATLAB software. The influences of all relevant parameters are shown in figures and tables. Two outcomes are developed for a precise range of the velocity ratio parameter. In particular, dual solutions are obtained when the needle and the fluid move in the opposite directions, while the solution is unique when they move in the same direction. The outcomes disclose that addition of nanoparticles into the base fluid upsurges the shear stress and the Nusselt number while decreasing the Sherwood number. Meanwhile, an upsurge in the needle size results in an uplift of the temperature and the concentration for the upper branch solution, whereas the velocity declines.
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Convecção , Nanoestruturas , Ligas , Hidrodinâmica , Modelos Teóricos , ÁguaRESUMO
Ischemic stroke is one of the leading causes of morbidity and mortality globally. Hundreds of clinical trials have proven ineffective in bringing forth a definitive and effective treatment for ischemic stroke, except a myopic class of thrombolytic drugs. That, too, has little to do with treating long-term post-stroke disabilities. These studies proposed diverse options to treat stroke, ranging from neurotropic interpolation to venting antioxidant activity, from blocking specific receptors to obstructing functional capacity of ion channels, and more recently the utilization of neuroprotective substances. However, state of the art knowledge suggests that more pragmatic focus in finding effective therapeutic remedy for stroke might be targeting intricate intracellular signaling pathways of the 'neuroinflammatory triangle': ROS burst, inflammatory cytokines, and BBB disruption. Experimental evidence reviewed here supports the notion that allowing neuroprotective mechanisms to advance, while limiting neuroinflammatory cascades, will help confine post-stroke damage and disabilities.
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Isquemia Encefálica/tratamento farmacológico , Doenças Neuroinflamatórias/tratamento farmacológico , Fármacos Neuroprotetores/farmacologia , Aldeídos/metabolismo , Barreira Hematoencefálica , Isquemia Encefálica/complicações , Isquemia Encefálica/imunologia , Isquemia Encefálica/patologia , Citocinas/fisiologia , Descoberta de Drogas , Endotelina-1/metabolismo , Regulação da Expressão Gênica , Humanos , Malondialdeído/metabolismo , Microglia/classificação , Microglia/imunologia , Terapia de Alvo Molecular , Doenças Neuroinflamatórias/etiologia , Doenças Neuroinflamatórias/fisiopatologia , Fármacos Neuroprotetores/uso terapêutico , Óxido Nítrico/metabolismo , Oxirredução , Espécies Reativas de Oxigênio/metabolismo , Receptores de Citocinas/fisiologiaRESUMO
Titanium alloy nanoparticle has a variety of applications in the manufacturing of soap and plastic, microsensors, aerospace design material, nano-wires, optical filters, implantation of surgical, and many biological treatments. Therefore, this research article discussed the influence of nonlinear radiation on magneto Williamson fluid involving titanium alloy particles through a thin needle. The arising system of partial differential equations is exercised by the similarity transformations to get the dimensional form of ordinary differential equations. The dual nature of solutions is obtained by implementing bvp4c. The study of stability has been carried out to check which of the results are physically applicable and stable. Influences of pertinent constraints on the flow field are discussed with the help of graphical representations and the method validation is shown in Table 1. The results imply that more than one result is established when the moving needle and the free-stream travel in the reverse directions. Moreover, the magnetic parameter accelerates the severance of boundary-layer flow, while the separation delays in the absence of the nanoparticle. The velocity gradient of nanofluid decays owing to the Williamson parameter in both branches of the outcome, while the temperature shrinks in the first or upper branch solution (stable one) and uplifts in the second or lower branch solution (unstable one). The size of the needle decreases the velocity in the upper solution and accelerates in the lower solution. The patterns of streamlines are more complicated due to the reverse direction of the free stream and thin needle.
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Ferroliquids are an example of a colloidal suspension of magnetic nanomaterials and regular liquids. These fluids have numerous applications in medical science such as cell separation, targeting of drugs, magnetic resonance imaging, etc. The hybrid nanofluid is composed by scattering the magnetic nanomaterial of more than one type nanoparticles suspended into the base fluid. It has different scientific applications such as heat dissipation, dynamic sealing, damping, etc. Owing to the vast ferrofluid applications, the time-dependent squeezed flow of hybrid ferroliquids under the impact of non-linear radiation and mixed convection within two disks was explored for the first time in this analysis. Here, the cobalt and magnetite ferrofluids are considered and scattered in a 50%:50% mixture of water-EG (ethylene glycol). The similarity technique is used to reduce the leading PDEs into coupled non-linear ODEs. The transmuted equations together with recommended boundary restrictions are numerically solved via Matlab solver bvp4c. The opposing and assisting flows are considered. The impacts of an emerging parameter on fluid velocity and temperature field of hybrid ferroliquids are examined through the different graphical aids. The results showed that the opposite trend is scrutinized due to the magnetic influence on the temperature and velocity in the case of assisting and opposing flows. The velocity augments due to the volume fraction of nanoparticles in the assisting flow and declines in the opposing flow, while the opposite direction is noticed in the temperature field.
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The mathematical modeling and numerical simulation are conferred to offer the novel perception of binary chemical reaction with an activation energy aspect on magneto flow comprising Cross liquid inspired by a moving wedge. The influences of Soret and Dufour are also presented. The similarity procedure is utilized to modify the leading PDEs into a non-linear system of ODEs and then analyzed through a significant technique namely bvp4c based on the collocation method. The impacts of varying distinct parameters under the temperature and the velocity distribution are explored and discussed with the support of the graphs. The outcomes indicate that the multiple results are attained for a specific amount of shrinking/stretching constraint. Furthermore, the Weissenberg number reduces the skin factor and speed up the heat and mass transport rate in the lower and upper branch solutions. Also, an assessment of current results with earlier published literature is made in the limiting case.