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1.
Food Funct ; 14(24): 10796-10813, 2023 Dec 11.
Artigo em Inglês | MEDLINE | ID: mdl-37982684

RESUMO

The present study aimed to investigate the influence of the food matrix on the bioaccessibility of free and bound (poly)phenols in different plant-based foods. These plant-based matrices included two fresh raw materials (tomato and red pepper), two minimally processed intermediate ingredients (dehydrated tomato and roasted red pepper), and two final plant-based and spreadable meat products whose main ingredients were tomato and red pepper (tomato pâté and pepper pâté, respectively). All samples underwent harmonized INFOGEST in vitro gastrointestinal digestion to simulate the digestive process. In the six studied matrices, 75 (poly)phenolic compounds were detected, the free fraction, in general, being higher than the bound fraction. The bioaccessibility values fluctuated between 5.83 and 38.38%, while the colon available index ranged from 10.40-298.81%. Among phenolic acids and flavonoids, in general, flavonoids were more bioaccessible than phenolic acids. The highest bioaccessibility values were obtained for fresh raw tomato and tomato pâté, while the lowest values were obtained for roasted red pepper and pepper pâté. In conclusion, except for the tomato pâté, food processing was detrimental to polyphenol bioaccessibility.


Assuntos
Antioxidantes , Produtos da Carne , Fenol , Fenóis/análise , Flavonoides , Digestão
2.
Plants (Basel) ; 9(12)2020 Dec 14.
Artigo em Inglês | MEDLINE | ID: mdl-33327480

RESUMO

Vegetable soups and creams have gained popularity among consumers worldwide due to the wide variety of raw materials (vegetable fruits, tubers, bulbs, leafy vegetables, and legumes) that can be used in their formulation which has been recognized as a healthy source of nutrients (mainly proteins, dietary fiber, other carbohydrates, vitamins, and minerals) and bioactive compounds that could help maintain the body's health and wellbeing. In addition, they are cheap and easy to preserve and prepare at home, ready to eat, so in consequence they are very useful in the modern life rhythms that modify the habits of current consumption and that reclaim foods elaborated with natural ingredients, ecologic, vegans, less invasive production processes, agroindustry coproducts valorization, and exploring new flavors and textures. This review focuses on the nutritional and healthy properties of vegetable soups and creams (depending on the raw materials used in their production) highlighting their content in bioactive compounds and their antioxidant properties. Apart from the effect that some processing steps could have on these compounds, innovation trends for the development of healthier soups and creams adapted to specific consumer requirements have also been explored.

4.
J Neuroimmunol ; 312: 19-23, 2017 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-28886956

RESUMO

We aimed to evaluate the usefulness of sepsis biomarkers to predict stroke-associated infections. Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1), mid-regional pro-adrenomedullin (MR-proADM), presepsin (sCD14), and soluble urokinase-type plasminogen activator receptor (suPAR), were explored in 125 blood samples collected at different time-points. At baseline, MR-proADM was an independent predictor of infection [>0.94pg/mL, OR=3.63 (1.16-11.33), p=0.026], as well as suPAR at 24h [>2185.8pg/mL, OR=5.81 (1.05-32.26), p=0.044]. Both MR-proADM and suPAR were raised in patients with infections throughout the first week after stroke. These results are especially relevant for MR-proADM given its early elevation, which would allow early preventive interventions.


Assuntos
Adrenomedulina/sangue , Infecções/sangue , Infecções/etiologia , Fragmentos de Peptídeos/sangue , Precursores de Proteínas/sangue , Sepse , Acidente Vascular Cerebral/complicações , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Proteína C-Reativa/metabolismo , Estudos de Coortes , Feminino , Humanos , Receptores de Lipopolissacarídeos/sangue , Masculino , Glicoproteínas de Membrana/sangue , Projetos Piloto , Receptores Imunológicos/sangue , Análise de Regressão , Sepse/sangue , Sepse/diagnóstico , Sepse/etiologia , Acidente Vascular Cerebral/sangue , Fatores de Tempo , Receptor Gatilho 1 Expresso em Células Mieloides
5.
Stem Cells Int ; 2016: 8657173, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27525011

RESUMO

Background and Purpose. BM-MNC transplantation improves recovery in experimental models of ischemic stroke. Clinical trials are ongoing to test efficacy in stroke patients. However, whether cell dose is related to outcomes is not known. Methods. We performed a pooling data analysis of two pilot clinical trials with autologous BM-MNCs transplantation in ischemic stroke patients. Cell dose and route were analyzed to evaluate their relation to good outcome (m-Rankin scale [mRS] score 0-2) at 6 months. Results. Twenty-two patients were included. A median of 153 × 10(6) (±121 × 10(6)) BM-MNCs was injected. Intra-arterial route was used in 77.3% of cases. A higher number of cells injected were associated with better outcomes at 180 days (390 × 10(6) [320-422] BM-MNCs injected in those patients with mRS of 0-2 at 6 months versus 130 × 10(6) [89-210] in those patients with mRS 3-6, p = 0.015). In the intra-arterially treated patients, a strong correlation between dose of cells and disability was found (r = -0.63, p = 0.006). A cut point of 310 × 10(6) injected cells predicted good outcome with 80% sensitivity and 88.2% specificity. Conclusions. Similar to preclinical studies, a higher dose of autologous BM-MNC was related to better outcome in stroke patients, especially when more than 310 × 10(6) cells are injected. Further interventional studies are warranted to confirm these data.

6.
J Agric Food Chem ; 57(17): 7719-25, 2009 Sep 09.
Artigo em Inglês | MEDLINE | ID: mdl-19670887

RESUMO

"Horchata" is a vegetable milk obtained from tiger nuts. The solid waste from horchata production was analyzed for physicochemical and microbial properties, aiming to determine its potential use as a fiber source for the food industry. The solid waste contains a high proportion of total dietary fiber (59.71 g/100 g), composed mainly of insoluble dietary fiber (99.8%). It has a high water-holding capacity (8.01 g/g) and oil-holding capacity (6.92 g/g) and a low water absorption (1.79 g/g) and water adsorption (0.23 g/g) capacities, in comparison with other dietary fiber sources. The emulsifying ability was 70.33 mL/100 mL, and the wastes showed high emulsion stability (100 mL/100 mL). The physicochemical properties indicate that tiger nut byproducts are rich in fiber and may be considered a potential ingredient in a healthy diet. However, the microbial quality was poor, meaning that it must be pasteurized prior to its addition to any food product.


Assuntos
Cyperus/química , Fibras na Dieta , Adsorção , Bebidas , Fenômenos Químicos , Fibras na Dieta/microbiologia , Emulsificantes , Indústria Alimentícia , Alimentos Fortificados , Resíduos Industriais , Tubérculos/química , Pós , Água/química
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