Comparative assessment of condylar position in patients with temporomandibular disorder (TMD) and asymptomatic patients using cone-beam computed tomography.

BACKGROUND: Temporomandibular disorders (TMD) are the most common reason of non-dental pain in the orofacial region. A clinical examination of the temporomandibular joint (TMJ) with additional imaging is the most recommended procedure for TMD diagnosis. OBJECTIVES: The objective of this study was to evaluate the association between TMD and the condylar position in the glenoid fossa by examining a group of patients suffering from TMD compared with a control group of patients without TMD. In this study, we used cone-beam computed tomography (CBCT) images for measurements. MATERIAL AND METHODS: Sixty-five symptomatic joints were selected from 48 patients with TMD. Sixtyfive joints were selected from a total of 96 asymptomatic joints in the control group. The superior, anterior and posterior area of the joint, and the steepness of the articular eminence were measured on the CBCT images. The data was analyzed using Pearson's χ2 test. RESULTS: The position of the condyle was significantly more posterior in the joints with TMD, and more anterior and centric in the asymptomatic joints. Statistically, the vertical position of the condyle and the steepness of the articular eminence had no significant relation with the occurrence of TMD. CONCLUSIONS: In this study, we observed that the posterior condylar position is more common in TMD patients, but it is not the reason for diagnosing TMD, and the reason of the posterior position of the condyle should be investigated before any decisions pertaining to treatment are made. In future, studies should focus on evaluating how the position of the condyle will change after the treatment of patients with TMD.

Recombinant Human Bone Morphogenic Protein-2 Combined With Autogenous Bone Graft for Reconstruction of Alveolar Cleft.

Recombinant human bone morphogenic proteins (rhBMPs) have been introduced for reconstruction of alveolar defects. The volume of the bone formed at the cleft region may be related to rhBMP-2 dose. Greater side effects have been reported with increased doses of rhBMP-2. The aim of the present study was to assess the bone at the cleft area using low dose of rhBMP-2 combined with autogenous bone graft for reconstruction of the alveolar cleft. Patients with unilateral cleft lip and palate between the 11 to 14 years old were enrolled. After palatal expansion, autogenous graft was placed at the side of cleft in the control group (n = 6). In the BMP group, the rhBMP-2 was injected into the autogenous bone graft at the defect site (n = 5). Cone beam computed tomography (CBCT) images were taken of all patients immediately and 3 months after graft surgery to compare the density, thickness, and height of the bone graft between the 2 groups. Intermolar and interpremolar widths were also measured. The authors found less diminish of density and height of the bone graft 3 months postsurgery in patients with autogenous bone graft combined with rhBMP-2. However, significant difference in the relapse tendency of transverse dimension of the arch or thickness of the bone graft was not observed between the 2 groups. Thus, low dose rhBMP-2 combined with autogenous bone graft can be promising to reach predictable results after alveolar reconstruction in cleft lip and palate patients.