Percutaneous imaging-guided cryoablation for lung cancer.

Percutaneous cryoablation under imaging guidance has been proved to be a safe and effective method for ablation and debulking of tumors, providing radical cure or palliation, as the case may be, for patients with different stages of disease. The local control rate is high with cryoablation, and the complications are usually controllable, making it a reasonable choice in lung cancer treatment. In this paper the technique and mechanism of action of cryoablation are summarized, and studies performed on the application of percutaneous cryoablation in various stages of lung cancer are reviewed. Its emerging application in the treatment of pure ground-glass nodules (GGNs) is also introduced.

A novel strategy of vascular reconstruction after radical resection of an inferior vena cava leiomyosarcoma.

BACKGROUND: Vascular reconstruction after resection of a inferior vena cava (IVC) leiomyosarcoma remains a major challenge. In this study we describe a case of successful vascular reconstruction using a novel approach. METHODS: A patient underwent the surgical resection of an IVC tumor. The caudal stump of the IVC was then anastomosed to an 18-mm Dacron graft with bilateral 8-mm arms, which were anastomosed to the bilateral renal veins, respectively. RESULTS: Complete resolution of abdominal pain was achieved and the patient did well throughout the 12-month follow-up. No recurrent clinical symptoms were observed. Renal function was well maintained. CONCLUSIONS: This novel vascular reconstruction approach may be a feasible, effective surgical strategy for preservation of renal function for IVC leiomyosarcoma.

Effects of laser irradiation of acupuncture points Shenshu on ovariectomized rats.

BACKGROUND AND OBJECTIVE: The effect of laser acupuncture on obesity in postmenopausal women remains unknown. The aim of this study was to investigate the effects of this form of treatment using an animal model. MATERIALS AND METHODS: Seventy-seven female Sprague-Dawley rats were assigned into seven groups: normal control (Normal), sham-operation control (Sham), ovariectomized (OVX) control rats (OVX), OVX rats treated with estrogen (OVX + E), and three groups of ovariectomized rats treated with laser acupuncture (OVX + L). Bilateral ovaries were removed to decrease estrogen levels. After 2 wk, semiconductor laser irradiation was administered to bilateral Shenshu (BL 23) acupoints of rats in the three OVX + L groups at 12, 30, and 60 J/cm(2), respectively. Changes in body weight and pituitary estrogen receptor (ER) mRNA expression were analyzed. Morphological differences in the uterus and pituitary glands were also observed. RESULTS: The OVX group exhibited marked weight gain and a significant decrease in pituitary ERα mRNA expression. Semiconductor laser irradiation at 30 J/cm(2) reduced body weight and increased ERα expression compared with the control, whereas irradiation at 12 or 60 J/cm(2) presented slightly weaker effects. Significant differences in pituitary ERß mRNA were not observed due to lack of optical density data. CONCLUSIONS: The semiconductor laser irradiation of bilateral Shenshu (BL 23) acupoints can exert beneficial effects on OVX rats through reducing body weight and increasing pituitary ERα expression, and 30 J/cm(2) was the most effective dose among those used.