Exploration and Research on Smart Sports Classrooms in Colleges in the Information Age.

Smart classrooms, made possible by the growing use of Internet information technology in the sphere of education, as one of the important foundations for the realization of smart education, have become the current hot direction of the development of educational information innovation and intend to propose some ideas and directions for smart sports teaching research in IA colleges and universities. The smart classroom is an intelligent and efficient classroom created by the "Internet +" way of thinking and the new generation of information technologies such as big data and cloud computing. This article puts forward the exploratory research methods of smart sports classrooms in colleges and universities in the IA, methods, such as document retrieval, expert interviews, questionnaire surveys, and practical research, and field investigation method, which are used in the exploration and research of college smart sports classrooms in the IA experiment. According to the findings of this study, 96.34 percent of students have a positive attitude toward the smart sports classroom teaching model, which is favorable to the growth of smart sports classroom teaching.

Metabolomic mechanisms of short chain chlorinated paraffins toxicity in rats.

Short chain chlorinated paraffins (SCCPs) have received increased interest worldwide since they were added to the list of controlled POPs in Annex A of the Stockholm Convention in 2017. Although many toxicological studies have already shown that SCCPs are hepatotoxic, nephrotoxic, and thyrotoxic to rodents, there have been few studies to date that have characterized changes in the metabolic pathways targeted by SCCPs. In this study, a UPLC-Q-TOF-MS based plasma metabolomics approach was used to investigate the toxicity of SCCPs in rats. Liver and kidney injury occurred rapidly after high-dose SCCP exposure, and the most relevant pathways affected were energy metabolism, amino acid metabolism, glycerophospholipid metabolism, nucleotide metabolism, and vitamin B metabolism. Exposure to SCCPs inhibited the tricarboxylic acid cycle and accelerated degradation. Fluctuating levels of phospholipids and nucleotides may have contributed to the neurotoxicity of SCCPs. In addition, the down regulation of folic acid induced by SCCPs may have led to malformations during the early development of laboratory animals. These results suggested that high exposure levels of SCCPs may have serious health risks and more research is needed to assess the health status of relevant occupational groups.