Topological Transformation of Hydrogen-Terminated Germanium to Germanium Nanosheets for Fast Lithium Storage.

Germanium has been recognized as a promising anode material for lithium-ion batteries (LIBs) due to its high theoretical capacity and excellent lithium-ion diffusivity. Nonetheless, it is challenging to enhance both the high-rate performance and long-term cycling stability simultaneously. This study introduces a novel heterostructure composed of germanium nanosheets integrated with graphene (Ge NSs@Gr). These nanosheets undergo an in situ phase transformation from a hydrogen-terminated multilayer germanium compound termed germanane (GeH) derived via topochemical deintercalation from CaGe2. This approach mitigates oxidation and prevents restacking by functionalizing the exfoliated germanane with octadecenoic organic molecules. The resultant germanium nanosheets retain their structural integrity from CaGe2 and present an exposed, active (111) surface that features an open crystal lattice, facilitating swift lithium-ion migration conducive to lithium storage. The composite material delivers a substantial reversible capacity of 1220 mA h g-1 at a current density of 0.2 C and maintains a capacity of 456 mA h g-1 even at an ultrahigh current density of 10 C over extended cycling. Impressively, a capacity of 316 mA h g-1 remains after 5000 cycles. The exceptional high-rate performance and durable cycling stability underscore the Ge NSs@Gr anode's potential as a highly viable option for LIBs.

Predicting histological grade in pediatric glioma using multiparametric radiomics and conventional MRI features.

Prediction of glioma is crucial to provide a precise treatment plan to optimize the prognosis of children with glioma. However, studies on the grading of pediatric gliomas using radiomics are limited. Meanwhile, existing methods are mainly based on only radiomics features, ignoring intuitive information about tumor morphology on traditional imaging features. This study aims to utilize multiparametric magnetic resonance imaging (MRI) to identify high-grade and low-grade gliomas in children and establish a classification model based on radiomics features and clinical features. A total of 85 children with gliomas underwent tumor resection, and part of the tumor tissue was examined pathologically. Patients were categorized into high-grade and low-grade groups according to World Health Organization guidelines. Preoperative multiparametric MRI data, including contrast-enhanced T1-weighted imaging, T2-weighted imaging, T2-weighted fluid-attenuated inversion recovery, diffusion-weighted images, and apparent diffusion coefficient sequences, were obtained and labeled by two radiologists. The images were preprocessed, and radiomics features were extracted for each MRI sequence. Feature selection methods were used to select radiomics features, and statistically significant clinical features were identified using t-tests. The selected radiomics features and conventional MRI features were used to train the AutoGluon models. The improved model, based on radiomics features and conventional MRI features, achieved a balanced classification accuracy of 66.59%. The cross-validated areas under the receiver operating characteristic curve for the classifier of AutoGluon frame were 0.8071 on the test dataset. The results indicate that the performance of AutoGluon models can be improved by incorporating conventional MRI features, highlighting the importance of the experience of radiologists in accurately grading pediatric gliomas. This method can help predict the grade of pediatric glioma before pathological examination and assist in determining the appropriate treatment plan, including radiotherapy, chemotherapy, drugs, and gene surgery.

Unveiling the bifunctional roles of Cetyltrimethylammonium bromide in construction of Nb2CTx@MoSe2 heterojunction for fast potassium storage.

Exploring robust electrode materials which could permit fast and reversible insertion/extraction of large K+ is a crucial challenge for potassium-ion batteries (PIBs). Smart interfacial design could facilitate electron/ion transport as well as assure the integrity of electrode. Herein, Cetyltrimethylammonium bromide (CTAB) was found to play bifunctional roles in construction of Nb2CTx@MoSe2 heterostructure. Firstly, functionalization of CTAB on the surface of Nb2CTx could influence the subsequent growth of MoSe2 by electrostatic effect, stereochemical effect and the synergetic Lewis acid-base interaction, leading to the formation of Nb2CTx@MoSe2 with tiled heterostructure. Secondly, the interlayer spacing of Nb2CTx was expanded from 0.77 to 1.21 nm owing to the pillar effect of CTAB. As excepted, the capacity retention was 80 % from 100 mA g-1 (406 mA h g-1) to 1000 mA g-1 concerning rate capability and the specific capacity maintained at 240 mA h g-1 (at 2000 mA g-1) over 300 cycles. The calculated DK values from Galvanostatic intermittent titration technique (GITT) measurement of the titled C-T-Nb2CTx@MoSe2@C electrode is two orders of magnitude larger than the traditional T-Nb2CTx@MoSe2@C electrode, further confirming intimate interface between MoSe2 and Nb2CTx could provide convenient potassium-ion transport channels and fast diffusion kinetics. Finally, ex-situ characterizations at different charging and discharging voltage stages, including ex-situ XRD/Raman/HRTEM/XPS have been carried out to reveal the potassium storage mechanism. This work provides a facile strategy for the regulation of interface engineering by the assist of CTAB which could extend to other MXenes-TMDs (Transition metal dichalcogenides) hybrid electrodes.

Design of Linear-Polymer-Coated Graphene Nanosheets with π-Conjugated Structure and Multi-Active-Center for Long-Lifespan and High-Rate Li-Storage Performance.

Organic material holds immense potential for Li-ion batteries (LIBs) due to their eco-friendly nature, high structural designability, abundant sources, and high theoretical capacity. However, the limited redox-active sites, low electronic conductivity, sluggish ionic diffusion, and high solubility hinder their practical application. Here, we reported the use of a linear polymer called poly(naphthalenetetracarboxylic dianhydride-pyrene-4,5,9,10-tetraone)-coated graphene nanosheets (NPT/rGO) as a cathode material for LIBs. The NPT polymer has a rotation angle of approximately 63° between each plane, which helps in exposing the active sites and preventing structural pulverization during cycling. The highly conjugated skeleton of the polymer, along with graphene, forms a synergistic effect through a π-π interaction. This combination enhances the conductivity and restricts solubility. Additionally, the linear structure of NPT and the two-dimensional rGO substrates work together to enhance charge transfer and ion diffusion rates, resulting in faster reaction kinetics. Consequently, NPT/rGO exhibits excellent electrochemical performance in terms of high capacity, superior cyclic stability, and good rate capability for LIBs. Moreover, through the combination of experimental investigations and theoretical simulations, a multiple electron reaction mechanism, an efficient Li-ion storage behavior, and a reversible dynamic evolution have been revealed. This study introduces a rational molecular design approach to enhance the electrochemical performance of polyimide derivatives, thereby contributing to the advancement of cutting-edge organic electrode materials for LIBs.

Co-culture of STRO1 + human gingival mesenchymal stem cells and human umbilical vein endothelial cells in 3D spheroids: enhanced in vitro osteogenic and angiogenic capacities.

Stem cell spheroid is a promising graft substitute for bone tissue engineering. Spheroids obtained by 3D culture of STRO1+ Gingival Mesenchymal Stem Cells (sGMSCs) (sGMSC spheroids, GS) seldom express angiogenic factors, limiting their angiogenic differentiation in vivo. This study introduced a novel stem cell spheroid with osteogenic and angiogenic potential through 3D co-culture of sGMSCs and Human Umbilical Vein Endothelial Cells (HUVECs) (sGMSC/HUVEC spheroids, GHS). GHS with varying seeding ratios of sGMSCs to HUVECs (GHR) were developed. Cell fusion within the GHS system was observed via immunofluorescence. Calcein-AM/PI staining and chemiluminescence assay indicated cellular viability within the GHS. Furthermore, osteogenic and angiogenic markers, including ALP, OCN, RUNX2, CD31, and VEGFA, were quantified and compared with the control group comprising solely of sGMSCs (GS). Incorporating HUVECs into GHS extended cell viability and stability, initiated the expression of angiogenic factors CD31 and VEGFA, and upregulated the expression of osteogenic factors ALP, OCN, and RUNX2, especially when GHS with a GHR of 1:1. Taken together, GHS, derived from the 3D co-culture of sGMSCs and HUVECs, enhanced osteogenic and angiogenic capacities in vitro, extending the application of cell therapy in bone tissue engineering.

Air-Stable and Low-Cost High-Voltage Hydrated Eutectic Electrolyte for High-Performance Aqueous Aluminum-Ion Rechargeable Battery with Wide-Temperature Range.

Aqueous aluminum-ion batteries (AAIBs) are considered as a promising alternative to lithium-ion batteries due to their large theoretical capacity, high safety, and low cost. However, the uneven deposition, hydrogen evolution reaction (HER), and corrosion during cycling impede the development of AAIBs, especially under a harsh environment. Here, a hydrated eutectic electrolyte (AATH40) composed of Al(OTf)3, acetonitrile (AN), triethyl phosphate (TEP), and H2O was designed to improve the electrochemical performance of AAIBs in a wide temperature range. The combination of molecular dynamics simulations and spectroscopy analysis reveals that AATH40 has a less-water-solvated structure [Al(AN)2(TEP)(OTf)2(H2O)]3+, which effectively inhibits side reactions, decreases the freezing point, and extends the electrochemical window of the electrolyte. Furthermore, the formation of a solid electrolyte interface, which effectively inhibits HER and corrosion, has been demonstrated by X-ray photoelectron spectroscopy, X-ray diffraction tests, and in situ differential electrochemical mass spectrometry. Additionally, operando synchrotron Fourier transform infrared spectroscopy and electrochemical quartz crystal microbalance with dissipation monitoring reveal a three-electron storage mechanism for the Al//polyaniline full cells. Consequently, AAIBs with this electrolyte exhibit improved cycling stability within the temperature range of -10-50 °C. This present study introduces a promising methodology for designing electrolytes suitable for low-cost, safe, and stable AAIBs over a wide temperature range.

Evidence that a Novel Chalcone Derivative, Compound 27, Acts on the Epithelium Via the PI3K/AKT/Nrf2-Keap1 Signaling Pathway, to Mitigate LPS-Induced Acute Lung Injury in Mice.

Acute lung injury (ALI) is a highly heterogeneous clinical syndrome and an important cause of mortality in critically ill patients, with limited treatment options currently available. Chalcone, an essential secondary metabolite found in edible or medicinal plants, exhibits good antioxidant activity and simple structure for easy synthesis. In our study, we synthesized a novel chalcone derivative, compound 27 (C27). We hypothesized that C27 could be a potential treatment for acute respiratory distress syndrome (ARDS). Therefore, the protective effects of C27 on lung epithelial cells during ALI and the underlying molecular mechanisms were investigated. In vivo, Intratracheal instillation of LPS (10 mg/kg) was used to induce acute lung injury in mice. In vitro, the bronchial epithelial cell line (Beas-2b) was treated with 30 µM tert-butyl hydroperoxide (t-BHP) to simulate oxidative stress. Our findings demonstrate that pretreatment with C27 reduces LPS-induced oxidative destruction and cellular apoptosis in lung tissues of mice. Furthermore, it significantly attenuates t-BHP-induced cellular reactive oxygen species (ROS) generation, mitochondrial damage, and apoptosis in vitro. Mechanistically, the signaling pathway involving Nrf2-Keap1 and the downstream antioxidative proteins were activated by C27 in vivo. Additionally, PI3K inhibitor LY294002 and Nrf2 inhibitor ML385 abolished the effect of C27 in vitro, indicating that the protective effect of C27 is mediated via the PI3K/AKT/Nrf2-Keap1 pathway. Our study provides evidence that C27 protects against LPS-induced ALI by mitigating oxidative stress via activation of the PI3K/AKT/Nrf2-Keap1 signaling pathway. Therefore, we hypothesize that C27 represents a viable alternative for ALI therapy.

Plant growth-promoting rhizobacteria Pseudomonas aeruginosa HG28-5 improves salt tolerance by regulating Na+/K+ homeostasis and ABA signaling pathway in tomato.

Salinity stress badly restricts the growth, yield and quality of vegetable crops. Plant growth-promoting rhizobacteria (PGPR) is a friendly and effective mean to enhance plant growth and salt tolerance. However, information on the regulatory mechanism of PGPR on vegetable crops in response to salt stress is still incomplete. Here, we screened a novel salt-tolerant PGPR strain Pseudomonas aeruginosa HG28-5 by evaluating the tomatoes growth performance, chlorophyll fluorescence index, and relative electrolyte leakage (REL) under normal and salinity conditions. Results showed that HG28-5 colonization improved seedling growth parameters by increasing the plant height (23.7%), stem diameter (14.6%), fresh and dry weight in the shoot (60.3%, 91.1%) and root (70.1%, 92.5%), compared to salt-stressed plants without colonization. Likewise, HG28-5 increased levels of maximum photochemical efficiency of PSII (Fv/Fm) (99.3%), the antioxidant enzyme activities as superoxide dismutase (SOD, 85.5%), peroxidase (POD, 35.2%), catalase (CAT, 20.6%), and reduced the REL (48.2%), MDA content (41.3%) and ROS accumulation in leaves of WT tomatoes under salt stress in comparison with the plants treated with NaCl alone. Importantly, Na+ content of HG28-5 colonized salt-stressed WT plants were decreased by15.5% in the leaves and 26.6% in the roots in the corresponding non-colonized salt-stressed plants, which may be attributed to the higher K+ concentration and SOS1, SOS2, HKT1;2, NHX1 transcript levels in leaves of colonized plants under saline condition. Interestingly, increased abscisic acid (ABA) content and upregulation of ABA pathway genes (ABA synthesis-related genes NCED1, NCED2, NCED4, NECD6 and signal genes ABF4, ABI5, and AREB) were observed in HG28-5 inoculated salt-stressed WT plants. ABA-deficient mutant (not) with NCED1 deficiency abolishes the effect of HG28-5 on alleviating salt stress in tomato, as exhibited by the substantial rise of REL and ROS accumulation and sharp drop of Fv/Fm in the leaves of not mutant plants. Notably, HG28-5 colonization enhances tomatoes fruit yield by 54.9% and 52.4% under normal and saline water irrigation, respectively. Overall, our study shows that HG28-5 colonization can significantly enhance salt tolerance and improved fruit yield by a variety of plant protection mechanism, including reducing oxidative stress, regulating plant growth, Na+/K+ homeostasis and ABA signaling pathways in tomato. The findings not only deepen our understanding of PGPR regulation plant growth and salt tolerance but also allow us to apply HG28-5 as a microbial fertilizer for agricultural production in high-salinity areas.

Electropolymerized Bipolar Poly(2,3-diaminophenazine) Cathode for High-Performance Aqueous Al-Ion Batteries with An Extended Temperature Range of -20 to 45 °C.

Achieving reversible insertion/extraction in most cathodes for aqueous aluminum ion batteries (AAIBs) is a significant challenge due to the high charge density of Al3+ and strong electrostatic interactions. Organic materials facilitate the hosting of multivalent carriers and rapid ions diffusion through the rearrangement of chemical bonds. Here, a bipolar conjugated poly(2,3-diaminophenazine) (PDAP) on carbon substrates prepared via a straightforward electropolymerization method is introduced as cathode for AAIBs. The integration of n-type and p-type active units endow PDAP with an increased number of sites for ions interaction. The long-range conjugated skeleton enhances electron delocalization and collaborates with carbon to ensure high conductivity. Moreover, the strong intermolecular interactions including π-π interaction and hydrogen bonding significantly enhance its stability. Consequently, the Al//PDAP battery exhibits a large capacity of 338 mAh g-1 with long lifespan and high-rate capability. It consistently demonstrates exceptional electrochemical performances even under extreme conditions with capacities of 155 and 348 mAh g-1 at -20 and 45 °C, respectively. In/ex situ spectroscopy comprehensively elucidates its cation/anion (Al3+/H3O+ and ClO4 -) storage with 3-electron transfer in dual electroactive centers (C═N and -NH-). This study presents a promising strategy for constructing high-performance organic cathode for AAIBs over a wide temperature range.

Elastic MXene conductive layers and electrolyte engineering enable robust potassium storage.

The precisely engineered structures of materials greatly influence the manifestation of their properties. For example, in the process of alkali metal ion storage, a carefully designed structure capable of accommodating inserted and extracted ions will improve the stability of material cycling. The present study explores the uniform distribution of self-grown carbon nanotubes to provide structural support for the conductive and elastic MXene layers of Ti3C2Tx-Co@NCNTs. Furthermore, a compatible electrolyte system has been optimized by analyzing the solvation structure and carefully regulating the component in the solid electrolyte interphase (SEI) layer. Mechanistic studies demonstrate that the decomposition predominantly controlled by FSI- leads to the formation of a robust inorganic SEI layer enriched with KF, thus effectively inhibiting irreversible side reactions and major structural deterioration. Confirming our expectations, Ti3C2Tx-Co@NCNTs exhibits an impressive reversible capacity of 260 mA h g-1, even after 2000 cycles at 500 mA g-1 in 1 M KFSI (DME), surpassing most MXene-based anodes reported for PIBs. Additionally, density functional theory (DFT) calculations verify the superior electronic conductivity and lower K+ diffusion energy barriers of the novel superstructure of Ti3C2Tx-Co@NCNTs, thereby affirming the improved electrochemical kinetics. This study presents systematic evaluation methodologies for future research on MXene-based anodes in PIBs.

A covalent organic framework as a dual-active-center cathode for a high-performance aqueous zinc-ion battery.

Organic electrode materials have shown significant potential for aqueous Zn ion batteries (AZIBs) due to their flexible structure designability and cost advantage. However, sluggish ionic diffusion, high solubility, and low capacities limit their practical application. Here, we designed a covalent organic framework (TA-PTO-COF) generated by covalently bonding tris(4-formylbiphenyl)amine (TA) and 2,7-diaminopyrene-4,5,9,10-tetraone (PTO-NH2). The highly conjugated skeleton inside enhances its electron delocalization and intermolecular interaction, leading to high electronic conductivity and limited solubility. The open channel within the TA-PTO-COF provides ionic diffusion pathways for fast reaction kinetics. In addition, the abundant active sites (C[double bond, length as m-dash]N and C[double bond, length as m-dash]O) endow the TA-PTO-COF with a large reversible capacity. As a result, the well-designed TA-PTO-COF cathode delivers exceptional capacity (255 mA h g-1 at 0.1 A g-1), excellent cycling stability, and a superior rate capacity of 186 mA h g-1 at 10 A g-1. Additionally, the co-insertion mechanism of Zn2+/H+ within the TA-PTO-COF cathode is revealed in depth by ex situ spectroscopy. This study presents an effective strategy for developing high-performance organic cathodes for advanced AZIBs.

Design of a bipolar organic small-molecule cathode with mesoporous nanospheres structure for long lifespan and high-rate Li-storage performance.

Organic small-molecule compounds have become promising cathode materials for high-performance lithium-ion batteries (LIBs) due to their high theoretical capacity, efficient utilization of active sites, low cost, and sustainability. However, severe dissolution and poor electronic conductivity limit their further practical applications. Herein, we have synthesized an insoluble organic small molecule, ferrocenyl-3-(λ1-azazyl) pyrazinyl [2,3-f] [1,10] phenanthrolino-2-amine (FCPD), by grafting ferrocene onto pyrazino[2,3-f] [1,10] phenanthroline-2,3-diamine (PPD). The combination of ferrocene (p-type Fe2+ moiety) and PPD (n-type C[double bond, length as m-dash]N groups) in a bipolar manner endows the target FCPD cathode with an increased theoretical capacity and a wide voltage window. The highly conjugated π-π aromatic skeleton inside enhances FCPD's electron delocalization and promotes strong interaction between FCPD units. Additionally, the mesoporous structure within the FCPD can provide numerous electroactive sites, contact area, and ion diffusion channels. Benefiting from the bipolar feature, aromatic, and mesoporous structure, the FCPD cathode demonstrates a large capacity of 250 mA h g-1 at 0.1 A g-1, a long lifespan of 1000 cycles and a high-rate capability of 151 mA h g-1 at 5 A g-1 along with a wide voltage window (1.2-3.8 V). Additionally, in situ synchrotron FT-IR and ex situ XPS reveal its dual ion storage mechanism in depth. Our findings provide essential insights into exploring the molecular design of advanced organic small molecules.

A novel technique to harvest bone autografts with mild local hyperthermia and enhanced osteogenic bone quality: a preclinical study in dogs.

BACKGROUND: Guided bone regeneration (GBR) involves collecting bone autografts with high bio-quality and efficiency. The current non-irrigated low-speed drilling has been limited for broader application in bone autograft harvest due to its low efficiency, inability to conduct buccal cortical perforation, and dependence on simultaneous implant placement. Increasing the drilling speed helps improve the efficiency but may incur thermal-mechanical bone damage. Most studies have addressed thermal reactions during bone drilling on non-vital models, which is irrelevant to clinical scenarios. Little has been known about bone's in vivo thermal profiles under non-irrigated higher-speed drilling and its influences on the resulting bone chips. AIM: A novel technique for bone harvest and cortical perforation via in-situ non-irrigated higher-speed drilling was proposed and investigated for the first time. METHODS: The third mandible premolars of eight beagles were extracted and healed for three months. Sixteen partial edentulous sites (left and right) were randomized into four groups for bone autograft harvest without irrigation: chisel, 50 rpm drilling, 500 rpm drilling, and 1000 rpm drilling. Bone chips were harvested on the buccal plates of the missing tooth. An infrared camera and an implantable thermocouple collaboratively monitored in vivo real-time bone temperature at the drilling sites. In vitro performances of cells from bone chips, including cell number, viability, proliferation, migration, ALP activity, in vitro mineralization, mRNA transcriptional level of osteogenic genes and heat shock protein 70 (HSP-70), and HSP-70 expression at the protein level were also studied. RESULTS: 500 rpm produced mild local hyperthermia with a 2-6 °C temperature rise both on the cortical surface and inside the cortical bone. It also held comparable or enhanced cell performances such as cell number, viability, proliferation, migration, ALP activity, in vitro mineralization, and osteogenic genes expression. CONCLUSIONS: In-situ non-irrigated higher-speed drilling at 500 rpm using a screw drill is versatile, efficient, and thermal friendly and improves the bio-quality of bone chips. Our novel technique holds clinical translational potential in GBR application.

Architecting carbon-coated Mo2CTx/MoSe2 heterostructures enables robust potassium storage.

Herein, carbon-coated MoSe2 decorated Mo2CTx MXene heterostructures (MoSe2/Mo2CTx@C) have been fabricated. Mo2CTx works as a dual-function electron/ion conductor, which not only provides high conductivity and mechanical strength, but also prevents the severe self-aggregation of few layered MoSe2 nanosheets. The high reversible capacities of 405 mA h g-1 at 100 mA g-1 after 150 cycles and 258 mA h g-1 at 2000 mA g-1 after 400 cycles could be achieved for a potassium-ion battery.

Nanostructured Porous Polymer with Low Volume Expansion, Structural Distortion, and Gradual Activation for High and Durable Lithium Storage.

Organic compounds exhibit great potential as sustainable, tailorable, and environmentally friendly electrode materials for rechargeable batteries. However, the intrinsic defects of organic electrodes, including solubility, low ionic conductivity, and restricted electroactivity sites, will inevitably decrease the cycling life and capacity. We herein designed and prepared nanostructured porous polymers (NPP) with a simple one-pot method to overcome the above defects. Theoretical calculations and experimental results demonstrate that the as-synthesized NPP exhibited low volume expansion, molecular-structural distortion, and a gradual function activation process during cycling, thus exhibiting superior, high, and durable lithium storage. The gradual molecular distortion during the lithium storage processes provides more redox-active sites for Li storage, increasing the Li-storage capacity. Ex situ spectrum studies reveal the redox reaction mechanism of Li storage and demonstrate a gradual activation process during the repeated charging/discharging until the full storage of 18 Li ions is achieved. Additionally, a real-time observation on the NPP anode by in situ transmission electron microscope reveals a slight volume expansion during the repeating lithiation and delithiation processes, ensuring its structural integrity during cycling. This quantitative work for high-durability lithium storage could be of immediate benefit for designing organic electrode materials.

Field investigation combined with modeling uncovers the ecological heterogeneity of Aedes albopictus habitats for strategically improving systematic management during urbanization.

BACKGROUND: Aedes albopictus is an invasive vector of serious Aedes-borne diseases of global concern. Habitat management remains a critical factor for establishing a cost-effective systematic strategy for sustainable vector control. However, the community-based characteristics of Ae. albopictus habitats in complex urbanization ecosystems are still not well understood. METHODS: A large-scale investigation of aquatic habitats, involving 12 sites selected as representative of four land use categories at three urbanization levels, was performed in Guangzhou, China during 2015-2017. The characteristics and dynamics of these Ae. albopictus habitats were assessed using habitat-type composition, habitat preference, diversity indexes and the Route index (RI), and the temporal patterns of these indexes were evaluated by locally weighted scatterplot smoothing models. The associations of RI with urbanization levels, land use categories and climatic variables were inferred using generalized additive mixed models. RESULTS: A total of 1994 potential habitats and 474 Ae. albopictus-positive habitats were inspected. The majority of these habitats were container-type habitats, with Ae. albopictus showing a particularly higher habitat preference for plastic containers, metal containers and ceramic vessels. Unexpectedly, some non-container-type habitats, especially ornamental ponds and surface water, were found to have fairly high Ae. albopictus positivity rates. Regarding habitats, the land use category residential and rural in Jiangpu (Conghua District, Guangzhou) had the highest number of Ae. albopictus habitats with the highest positive rates. The type diversity of total habitats (H-total) showed a quick increase from February to April and peaked in April, while the H-total of positive habitats (H-positive) and RIs peaked in May. RIs mainly increased with the monthly average daily mean temperature and monthly cumulative rainfall. We also observed the accumulation of diapause eggs in the winter and diapause termination in the following March. CONCLUSIONS: Ecological heterogeneity of habitat preferences of Ae. albopictus was demonstrated in four land use categories at three urbanization levels. The results reveal diversified habitat-type compositions and significant seasonal variations, indicating an ongoing adaptation of Ae. albopictus to the urbanization ecosystem. H-positivity and RIs were inferred as affected by climatic variables and diapause behavior of Ae. albopictus, suggesting that an effective control of overwintering diapause eggs is crucial. Our findings lay a foundation for establishing a stratified systematic management strategy of Ae. albopictus habitats in cities that is expected to complement and improve community-based interventions and sustainable vector management.

The clinical significance and application of the peri-implant phenotype in dental implant surgery: a narrative review.

Background and Objective: In recent years, the concept of the peri-implant phenotype has become a new standard for the clinical evaluation of the soft and hard tissues surrounding dental implants. Improving this phenotype enhances the likelihood of achieving long-term favorable results and is a necessary consideration during implant planning. Stable peri-implant tissue support is also crucial for the functional and aesthetic value of implant restoration. Herein, the authors review the clinical significance of the peri-implant phenotype and assess the timing of treatment strategies for improving peri-implant phenotype elements. Methods: A literature search was performed to retrieve papers on peri-implant tissue management and clinical outcomes published up to November 24th, 2022 in PubMed, Web of Science, EMBASE, and Scopus. Key Content and Findings: The optimal time to improve peri-implant bone thickness (PBT) is with augmentation procedures before implant surgery or at the same time as first-stage surgery. Similarly, issues associated with keratinized mucosa width (KMW) and mucosal thickness (MT) should be addressed before final restoration. The establishment of supracrestal tissue height (STH) depends on the MT and implant depth of the patient. Furthermore, special attention should be paid to the effect of the peri-implant phenotype on the prognosis of immediate implant placement in the aesthetic zone. Conclusions: The long-term success of implant restoration depends on careful planning that considers appropriate interventions for improving the peri-implant phenotype at different stages of treatment to reduce iatrogenic variables.

A liquid metal-fluoropolymer artificial protective film enables robust lithium metal batteries at sub-zero temperatures.

Batteries that are both high-energy-density and durable at sub-zero temperatures are highly desirable for deep space and subsea exploration and military defense applications. Our design incorporates a casting membrane technology to prepare a gallium indium liquid metal (LM)/fluoropolymer hybrid protective film on a lithium metal anode. The LM not only spontaneously forms a passivation alloy layer with lithium but also reduces the nucleation potential barrier and homogenizes the Li+ flux on the surface of the lithium anode. The fluoropolymer's polar functional groups (-C-F-) effectively induce targeted dispersion of gallium indium seeds, and the unique pit structure on the surface provides oriented sites for lithium plating. By implementing these strategies optimally, the protected lithium metal anode remains in operation at a current density of 20 mA cm-2 with an over-potential of about 50.4 mV after 500 h, and the full cells have a high capacity retention rate of up to 98.5% at a current density of 0.5 C after 100 cycles. Furthermore, the battery shows improved low temperature performance at -30 °C, validating the potential of the protective film to enable battery operation at sub-zero temperatures.

Cold-Chain-Food-Related COVID-19 Surveillance in Guangzhou between July 2020 and December 2022.

OBJECTIVE: To monitor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA contamination in samples linked to imported cold-chain food and assess the situation from the implementation of a centralized supervision warehouse system in Guangzhou, Guangdong Province, China. METHODS: Swabs of workers and frozen-food-related samples were collected between July 2020 and December 2023 in Guangzhou, Guangdong Province. SARS-CoV-2 RNA was extracted and analyzed by a real-time quantitative polymerase chain reaction using the commercially available SARS-CoV-2 nucleic acid test kit. The risk level and food source were monitored simultaneously. RESULTS: A total of 283 positive cold-chain events were found in Guangzhou since the first cold-chain-related event of the coronavirus disease 2019 pandemic was identified in July 2020. Most positive samples were a low-to-medium risk, and the cycle threshold value was >30. No live virus was detected, and no staff came into direct contact with a live virus. In total, 87.63% of positive events were identified through sampling and testing at the centralized food warehouse. CONCLUSION: Cold-chain food has a relatively low risk of transmitting SARS-CoV-2. Centralized food storage can be used as an effective method to control this risk, and this measure can also be used for other food-related, contact-transmitted diseases.

Concentration-Gradient Nb-Doping in a Single-Crystal LiNi0.83Co0.12Mn0.05O2 Cathode for High-Rate and Long-Cycle Lithium-Ion Batteries.

Single-crystalline nickel-rich layered oxides are promising cathode materials for building high-energy lithium-ion batteries because of alleviated particle cracking and irreversible phase transitions upon cycling, compared with their polycrystalline counterparts. Under a high state of charge, parasitic reactions tend to occur at the cathode-electrolyte interface, which could result in sluggish Li-ion diffusion kinetics and quickly faded electrochemical performance of cathodes. In this work, a concentration-gradient niobium-doping strategy was applied to modify the single-crystal LiNi0.83Co0.12Mn0.05O2 cathode, with Nb concentration decreasing linearly from the surface to the core of the particle. As a result, the Nb-rich surface functions as an electrochemically active protective layer against electrolyte corrosion and transition metal dissolution, while the Nb-deficient core contributes to a higher capacity. The linear concentration gradient also minimizes structural transition from the surface to the core and helps to maintain structural integrity during repeated Li (de)intercalation. In addition, Nb-doping also assists to alleviate Li+/Ni2+ mixing and increases the interlayer distance to enable faster Li-ion diffusion kinetics. By taking these advantages, the Nb-doped cathode materials (containing 1.0 atom% Nb) demonstrate a high reversible capacity, a high capacity retention, and improved rate capabilities. This work provides a general and facile approach to improve the storage performance of layered-oxide cathode materials by rationally tuning the bulk structure and interface with the electrolyte.