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Medicine (Baltimore) ; 100(12): e25266, 2021 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-33761727

RESUMO

INTRODUCTION: The objective is to analyze the clinical diagnosis and treatment of children with rescindable posterior encephalopathy syndrome (PRES) and intracranial hemorrhage (ICH) to improve the pediatrician's understanding of PRES combined with ICH in children. PATIENT CONCERNS AND DIAGNOSIS: After liver transplantation, the patient developed symptoms of epilepsy and coma. Meanwhile, massive necrosis of acute cerebral infarction and small hemorrhage was observed in the left cerebellar hemisphere and left occipital lobe, respectively. The above symptoms were initially diagnosed as PRES. INTERVENTIONS AND OUTCOMES: After adjusting the anti-rejection drug regimen, it was found that the child's neurological symptoms were relieved, and the limb motor function gradually recovered during follow-up. Imaging examination showed significant improvement on abnormal signals in brain. CONCLUSION: In general, children with PRES may further develop ICH and contribute to a poor prognosis. Early diagnosis, detection of risk factors and timely adjustment of medication regimen are the keys to prevent irreversible brain damage.


Assuntos
Ductos Biliares/anormalidades , Atresia Biliar/cirurgia , Infarto Cerebral , Terapia de Imunossupressão , Hemorragias Intracranianas , Síndrome da Leucoencefalopatia Posterior , Risco Ajustado/métodos , Atresia Biliar/diagnóstico , Atresia Biliar/etiologia , Encéfalo/diagnóstico por imagem , Dano Encefálico Crônico/etiologia , Dano Encefálico Crônico/prevenção & controle , Infarto Cerebral/diagnóstico , Infarto Cerebral/etiologia , Pré-Escolar , Diagnóstico Precoce , Humanos , Terapia de Imunossupressão/efeitos adversos , Terapia de Imunossupressão/métodos , Hemorragias Intracranianas/diagnóstico , Hemorragias Intracranianas/etiologia , Transplante de Fígado/métodos , Imageamento por Ressonância Magnética/métodos , Masculino , Síndrome da Leucoencefalopatia Posterior/diagnóstico , Síndrome da Leucoencefalopatia Posterior/etiologia , Síndrome da Leucoencefalopatia Posterior/fisiopatologia , Síndrome da Leucoencefalopatia Posterior/terapia , Tomografia Computadorizada por Raios X/métodos
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