1.
Zhonghua Nei Ke Za Zhi
; 30(7): 426-8, 457, 1991 Jul.
Artigo
em Chinês
| MEDLINE
| ID: mdl-1684317
RESUMO
The cell surface phenotype of peripheral blood lymphocytes in patients with systemic lupus erythematosus (SLE) was studied with the anti-T4+, T8+ and T4+2H4+ monoclonal antibodies by flow cytometry. 13 patients with active SLE had a markedly low percentage of T4+2H4+ cells but had normal percentage of T8+ cells. Our results reveal that the influence of T cell to B cell is not only because of the quantity of T cells, also because of the function of T cells. The abnormality of T4+2H4+ cells may be important in the pathogenesis of SLE.