Systematic Review of Clinimetric Instruments to determine the severity of Non-segmental Vitiligo.

This systematic review of measurement instruments for vitiligo outcomes included validation articles published from 2011 to May 2018. According to the PRISMA statement, the search was carried out in EMBASE (via OvidSP); MEDLINE (via OvidSP and PubMed). The COSMIN taxonomy will be used to define the measurement properties. Inclusion criteria were original studies reporting measuring properties. Exclusion criteria were clinical trials using scales whose measurement properties were not assessed, studies of cross-cultural adaptation, scales focused on other aspects of the disease such as quality of life, satisfaction, disease's burden. Fourteen studies were identified, which described 15 instruments to measure vitiligo outcomes. Nine of them, measured properties related to the severity of the disease: Vitiligo extent score (VES), Self-Assessment Vitiligo Extent Score (SA-VES), Self-Assessed Vitiligo Area Scoring Index (SAVASI), Vitiligo Area Scoring Index (VASI), Vitiligo European Task Force assessment (VETFa), Vitíligo Noticeability Scale (VNS), Koebner's phenomenon in vitiligo score (K-VSCOR), Vitiligo Extent Tensity Index (VETI), Potential Repigmentation Index (PRI). The most effective tool to asses affected Body Surface Area (BSA) is VES. The VASI is useful to stratify by severity. There is not enough evidence to recommend the use of SAVASI. The VETFa does not offer any difference to calculate the affected BSA compared with the rule of 9's. The VNS and K-VSCOR lack of reliability evidence.

[Frontal fibrosing alopecia (FFA): Report on four cases and review of the literature]. / Alopecia frontal fibrosante (AFF): reporte de cuatro casos y revisión de la literatura.

Frontal fibrosing alopecia was recently described by Kossard, et al. as a progressive symmetrical recession of the frontal-temporal-parietal hairline affecting particularly postmenopausal women. Besides affecting the scalp, there are some cases in the literature with partial or total loss of the eyebrows, also involving the trunk, and superior extremities. Because the clinical, histological, and immunochemical findings are indistinguishable from those seen in lichen planopilaris, frontal fibrosing alopecia is now considered a localized variant of lichen planopilaris. We report four cases of Mexican postmenopausal women with this kind of dermatosis evaluated at the Dermatological Center Dr. Ladislao de la Pascua.

[Nail changes associated with distal renal tubular acidosis in pediatric patients]. / Cambios ungueales asociados a acidosis tubular renal (ATR) distal en pacientes pediátricos.

Renal tubular acidosis is a disease prevalent in childhood, responsible for a decrease in growth due inadequate acid-base levels regulation. It is well known that systemic conditions can generate or accompany nail changes by different pathophysiologic mechanisms, however no one has ever found or reported any association of onychopathy with renal tubular acidosis so far. That is why we would like to share our experience on this topic.