Insight into diversity change, variability and co-occurrence patterns of phytoplankton assemblage in headwater streams: a study of the Xijiang River basin, South China.

Phytoplankton has been used as a paradigm for studies of coexistence of species since the publication of the "paradox of the plankton." Although there are a wealth of studies about phytoplankton assemblages of lakes, reservoirs and rivers, our knowledge about phytoplankton biodiversity and its underlying mechanisms in mountain headwater stream ecosystems is limited, especially across regional scales with broad environmental gradients. In this study, we collected 144 phytoplankton samples from the Xijiang headwater streams of the Pearl River across low altitude (< 1,000 m) located in Guangxi province, intermediate altitude (1,000 m < altitude <2,000 m) in Guizhou province and high altitude (> 2,000 m) in Yunnan province of China. Our study revealed high phytoplankton diversity in these streams. Freshwater phytoplankton, including cyanobacteria, Bacillariophyta, Chlorophyta, Rhodophyta, Chrysophyta, Euglenophyta, Glaucophyta, Phaeophyta and Cryptophyta, were all detected. However, phytoplankton alpha diversity exhibited a monotonic decreasing relationship with increasing altitude. High altitudes amplified the "isolated island" effect of headwater streams on phytoplankton assemblages, which were characterized by lower homogeneous selection and higher dispersal limitation. Variability and network vulnerability of phytoplankton assemblages increased with increasing altitudes. Our findings demonstrated diversity, variability and co-occurrence patterns of phytoplankton assemblages linked to environmental factors co-varying with altitude across regional scales.

A re-conceptualisation of the Batwa's right to recognition as a minority and indigenous people in Rwanda: A human rights-based approach.

There have been divergent views by various human rights scholars and actors on how to address the question of vulnerability among indigenous and minority groups in Rwanda. Even though factors influencing vulnerability among these groups have received increasing scholarly attention, findings from these studies fall short of reflecting on the role of identity and discrimination. Whereas the government in Rwanda after the 1994 genocide sought to enhance unity and reconciliation by outlawing all ethnic identities, and instead conflating all vulnerable groups into a nomenclature namely, a Historically Marginalised People (HMP), a divergent group of scholars, human rights activists, the United Nations and African Union's instruments of human rights describe this approach as antithetical to the promotion and protection of the rights of indigenous and minority groups. Using the human rights-based approach, this paper critically interrogates the issue of identity and how it has affected the enjoyment of the rights among the minority and indigenous Batwa people in Rwanda. The study employed a qualitative research design with data collected through Focus Group Discussions (FGDs) as well as in-depth interviews (IDIs). Respondents included members of the Batwa community, officials of selected public institutions, leaders in Non-Governmental Organisations (NGOs), and cooperative societies working towards the promotion of rights of the HMP. Data analysis involved the process of transcription and coding of data and the eventual reflexive thematic analysis. The findings show that the rights of the Batwa community to recognition and self-identity have varied meanings and implications to different members of the community as well as officials from public institutions and other relevant actors. To the existing research, the study affirms that the inconsistencies surrounding the Batwa's identity have accentuated their vulnerability. In terms of policy, the study suggests that in the short run, the Batwa community may require enhanced special temporary social protection measures in order to ameliorate their conundrum arising from identity ambiguity without compromising Rwanda's national unity. Further studies, should consider the role of land, forest and culture in further marginalising the Batwa, as well as quantitative methodology for inferential analysis.

Reevaluating the "deaths of despair" narrative: Racial/ethnic heterogeneity in the trend of psychological distress-related death.

Despite the significant scientific advancement in deciphering the "deaths of despair" narrative, most relevant studies have focused on drug-, alcohol-, and suicide-related (DAS) deaths. This study directly investigated despair as a determinant of death and the temporal variation and racial heterogeneity among individuals. We used psychological distress (PD) as a proxy for despair and drew data from the US National Health Interview Survey-Linked Mortality Files 1997 to 2014, CDC (Centers for Disease Control and Prevention) Multiple Cause of Death database 1997 to 2014, CDC bridged-race population files 1997 to 2014, Current Population Survey 1997 to 1999, and the American Community Survey 2000 to 2014. We used Cox proportional hazards models to estimate mortality hazard ratios of PD and compared age-standardized PD- and DAS-related mortality rates by race/ethnicity and over time. We found that while Whites had a lower prevalence of PD than Blacks and Hispanics throughout the whole period, they underwent distinctive increases in PD-related death and have had a higher PD-related mortality rate than Blacks and Hispanics since the early 2000s. This was predominantly due to Whites' relatively high and increasing vulnerability to PD less the prevalence of PD. Furthermore, PD induced a more pervasive mortality consequence than DAS combined for Whites and Blacks. In addition, PD- and DAS-related deaths displayed a concordant trend among Whites but divergent patterns for Blacks and Hispanics. These findings suggest that 1) DAS-related deaths underestimated the mortality consequence of despair for Whites and Blacks but overestimated it for Hispanics; and 2) despair partially contributed to the DAS trend among Whites but probably not for Blacks and Hispanics.

Age differences in psychological distress during the COVID-19 pandemic: March 2020 - June 2021.

In March 2020, COVID-19 brought illness, lockdowns, and economic turmoil worldwide. Studies from March-April 2020 reported increased psychological distress, especially among younger (vs. older) adults. Here, we examine whether age differences persisted in a 29-wave longitudinal survey conducted with an American national life-span sample over the first 16 months of the pandemic. Socio-emotional selectivity theory (SST) predicts that older age will be consistently associated with lower psychological distress due to life-span changes in motivation, while the strength and vulnerability integration model (SAVI) posits that age differences in psychological distress will diminish under prolonged stress. We find that younger adults consistently reported more psychological distress than older adults, though age differences did decrease over time. Prior diagnosis with anxiety or depression additionally predicted greater psychological distress throughout the study, but did not moderate age differences. We discuss implications for psychological theories of aging and interventions to reduce psychological distress.

Situações de vulnerabilidade vivenciadas por pessoas transexuais / Situaciones de vulnerabilidad que viven las personas transgénero / Situations of vulnerability experienced by transgender people

OBJETIVO: Analisar a percepção de pessoas transexuais sobre as situações preconceituosas vivenciadas no seu cotidiano. MÉTODO: Estudo descritivo, com abordagem qualitativa, realizado presencialmente entre os meses de junho e dezembro de 2018, com 25 pessoas transexuais dos municípios de Petrolina/PE e Juazeiro/BA. A coleta de dados ocorreu por meio de entrevistas semiestruturadas, que foram gravadas e transcritas na íntegra e esses dados analisados por meio da Análise de Conteúdo temática. RESULTADOS: Verificou-se que as pessoas transexuais percebem a ocorrência de situações de violência em seu cotidiano, evidenciada de diversas formas. Ao indagar sobre a violência e o preconceito sofrido, foi mencionado o medo, a visão diferente e preconceituosa das pessoas, as dificuldades no uso de banheiros públicos e a falta de informação quanto à diferenciação dos subgrupos da sigla LGBTQIA+. Quanto às dificuldades enfrentadas, foram citadas as barreiras de acesso à saúde, educação, inserção no mercado de trabalho e relacionamento familiar. CONCLUSÃO: Assim, considerando a complexidade dessa problemática na região estudada e no país como um todo, torna-se fundamental a participação política desses indivíduos em movimentações sociais da diversidade sexual e de gênero, de forma a se buscar a conscientização da sociedade a respeito dessa diversidade e, a partir disso, propor o planejamento e execução de ações que visem diminuir as dificuldades de pessoas transexuais em relação à garantia dos direitos fundamentais.

OBJECTIVE: To analyze the perception of transgender people about the prejudiced situations they experience in their daily lives. METHOD: Descriptive study, with a qualitative approach, carried out in person between June and December 2018, with 25 transgender people from the municipalities of Petrolina/PE and Juazeiro/BA. Data collection took place through semi-structured interviews, which were recorded and transcribed in full and these data were analyzed using thematic Content Analysis. RESULTS: It was found that transgender people perceive the occurrence of situations of violence in their daily lives, evidenced in different ways. When inquiring about the violence and prejudice suffered, fear, the different and prejudiced view of people, the difficulties in using public restrooms and the lack of information regarding the differentiation of subgroups of the acronym LGBTQIA+ were mentioned. As for the difficulties faced, barriers to access to health, education, insertion in the labor market and family relationships were cited. CONCLUSION: Thus, considering the complexity of this problem in the region studied and in the country as a whole, the political participation of these individuals in social movements of sexual and gender diversity becomes essential, in order to seek society's awareness of this diversity and, from this, propose the planning and execution of actions that aim to reduce the difficulties of transgender people in relation to the guarantee of fundamental rights.

OBJETIVO: Analizar la percepción de las personas transgénero sobre las situaciones de prejuicio que viven en su vida cotidiana. MÉTODO: Estudio descriptivo, con enfoque cualitativo, realizado de forma presencial entre junio y diciembre de 2018, con 25 personas transgénero de los municipios de Petrolina/PE y Juazeiro/BA. La recolección de datos ocurrió a través de entrevistas semiestructuradas, que fueron grabadas y transcritas en su totalidad y estos datos fueron analizados mediante el Análisis de Contenido temático. RESULTADOS: Se constató que las personas trans perciben la ocurrencia de situaciones de violencia en su cotidiano, evidenciado de diferentes formas. Al indagar sobre la violencia y los prejuicios sufridos, se mencionó el miedo, la mirada diferente y prejuiciosa de las personas, las dificultades para utilizar los baños públicos y la falta de información respecto a la diferenciación de subgrupos de las siglas LGBTQIA+. En cuanto a las dificultades enfrentadas, se mencionaron las barreras de acceso a la salud, la educación, la inserción en el mercado laboral y las relaciones familiares. CONCLUSIÓN: Así, considerando la complejidad de esta problemática en la región estudiada y en el país en su conjunto, la participación política de estas personas en los movimientos sociales de la diversidad sexual y de género se vuelve fundamental, con el fin de buscar la conciencia de la sociedad sobre esta diversidad y, a partir de ello, proponer la planificación y ejecución de acciones que apunten a reducir las dificultades de las personas transgénero en relación a la garantía de los derechos fundamentales.

Drought and society: Scientific progress, blind spots, and future prospects.

Human activities have increasingly intensified the severity, frequency, and negative impacts of droughts in several regions across the world. This trend has led to broader scientific conceptualizations of drought risk that account for human actions and their interplays with natural systems. This review focuses on physical and engineering sciences to examine the way and extent to which these disciplines account for social processes in relation to the production and distribution of drought risk. We conclude that this research has significantly progressed in terms of recognizing the role of humans in reshaping drought risk and its socioenvironmental impacts. We note an increasing engagement with and contribution to understanding vulnerability, resilience, and adaptation patterns. Moreover, by advancing (socio)hydrological models, developing numerical indexes, and enhancing data processing, physical and engineering scientists have determined the extent of human influences in the propagation of drought hazard. However, these studies do not fully capture the complexities of anthropogenic transformations. Very often, they portray society as homogeneous, and decision-making processes as apolitical, thereby concealing the power relations underlying the production of drought and the uneven distribution of its impacts. The resistance in engaging explicitly with politics and social power-despite their major role in producing anthropogenic drought-can be attributed to the strong influence of positivist epistemologies in engineering and physical sciences. We suggest that an active engagement with critical social sciences can further theorizations of drought risk by shedding light on the structural and historical systems of power that engender every socioenvironmental transformation. This article is categorized under:Climate, History, Society, Culture > Disciplinary Perspectives.

DNA methylation profiles in adults born at extremely low birth weight.

Effects of stresses associated with extremely preterm birth may be biologically "recorded" in the genomes of individuals born preterm via changes in DNA methylation (DNAm) patterns. Genome-wide DNAm profiles were examined in buccal epithelial cells from 45 adults born at extremely low birth weight (ELBW; ≤1000 g) in the oldest known cohort of prospectively followed ELBW survivors (Mage = 32.35 years, 17 male), and 47 normal birth weight (NBW; ≥2500 g) control adults (Mage = 32.43 years, 20 male). Sex differences in DNAm profiles were found in both birth weight groups, but they were greatly enhanced in the ELBW group (77,895 loci) versus the NBW group (3,424 loci), suggesting synergistic effects of extreme prenatal adversity and sex on adult DNAm profiles. In men, DNAm profiles differed by birth weight group at 1,354 loci on 694 unique genes. Only two loci on two genes distinguished between ELBW and NBW women. Gene ontology (GO) and network analyses indicated that loci differentiating between ELBW and NBW men were abundant in genes within biological pathways related to neuronal development, synaptic transportation, metabolic regulation, and cellular regulation. Findings suggest increased sensitivity of males to long-term epigenetic effects of extremely preterm birth. Group differences are discussed in relation to particular gene functions.

Sustained Stress Reduces the Age Advantages in Emotional Experience of Older Adults: Commentary on Carstensen et al. (2020).

Older age is characterized by more positive and less negative emotional experience. Recent work by Carstensen et al. (2020) demonstrated that the age advantages in emotional experience have persisted during the COVID-19 pandemic. In two studies, we replicated and extended this work. In Study 1, we conducted a large-scale test of the robustness of Carstensen and colleagues' findings using data from 23,350 participants in 63 countries. Our results confirm that age advantages in emotions have persisted during the COVID-19 pandemic. In Study 2, we directly compared the age advantages before and during the COVID-19 pandemic in a within-participants study (N = 4,370). We found that the age advantages in emotions decreased during the pandemic. These findings are consistent with theoretical proposals that the age advantages reflect older adults' ability to avoid situations that are likely to cause negative emotions, which is challenging under conditions of sustained unavoidable stress.

Cancer and Life Beyond It: Patient Testimony as a Contribution to Subjective Evidence.

Patient narratives are a very valuable literary and medical resource. They transcribe the experience of illness into the life stories of the subject and the author. A serious case of cancer triggers the very individual experience of vulnerability, suffering, dependence, and even contingency in the no longer 'open' future. Even after overcoming cancer, life is never the same again. Writing about one's own experience of cancer is a hermeneutic feat of strength with ethical and aesthetic implications. In the age of personalized and evidence-based medicine, patient narratives offer a particular and necessary supplement to the objectifying medical perspective, since they constitute expressions of subjective evidence. This article is based on the direct experience of cancer by the co-author of the narrative. The long history of her illness is presented chronologically in her own words and has been translated from Italian to English. This is followed by an essay, published here for the first time, on "the life beyond cancer", on the patient's time without tumors and the consequences of therapies and mutilating operations. Our methodological approach is based on Havi Carel's Phenomenology of Illness. The close reading of this pathography focuses on three aspects: (1) the effect and power of words; (2) the passage from wariness to awareness; and (3) the maintenance of personal quality of life during and after cancer.

Group II metabotropic glutamate receptor activation in the basolateral amygdala mediates individual differences in stress-induced changes in rapid eye movement sleep.

Group II metabotropic glutamate receptors (mGluR2/3s) have been implicated in stress and trauma related disorders including post-traumatic stress disorder (PTSD). PTSD is characterized by flashbacks, anxiety, and sleep disturbances. While many people are exposed to trauma in their lifetime, only a small percentage go on to develop PTSD, indicating individual differences in stress and emotional processing. Wistar strain rats display directionally different rapid-eye movement sleep (REM) responses to footshock stress, with resilient rats having no change or an increase in REM and vulnerable rats having a significant reduction in REM compared to baseline. The basolateral nucleus of the amygdala (BLA) is key in regulating individual differences in stress-induced alterations in sleep. Group II metabotropic glutamate receptors (mGluR2/3s) negatively modulate glutamate and are implicated in fear, fear memory, and sleep. The current study evaluated the effect of mGluR2/3 agonist LY379268 (LY37) in BLA on stress and fear memory induced changes in sleep, EEG spectra, behavioral fear expression and physiological stress. These data indicate that vulnerable rats treated with LY37 have an attenuation of the REM reductions generally seen in vulnerable rats. Furthermore, LY37 altered EEG spectra in the delta (0.5-4.5 Hz) and theta (5-9.5 Hz) frequency. LY37 did not impact behavioral fear expression or physiological stress. Therefore, mGluR2/3s within BLA are implicated in regulating individual differences in sleep responses to fear- and stress-related memories.

Some psychoanalytic reflections: femininity, feminism and fantasy in "APPLE TREE YARD".

This paper examines the interplay between femininity, feminism, and fantasy, based on the analysis of the protagonist of Apple Tree Yard, a British television mini series (2017) adapted by Amanda Coe from the novel of the same name by Louise Doughty (Apple Tree Yard. Farrar, Straus and Giroux, New York, 2013). This examination addresses the following questions: What causes a married, 52-year-old woman, with two grown children to engage in a reckless and perverse affair with a man she does not know? What unconscious fantasies have been evoked by the traumas of her childhood and of her adult life, and how do these unconscious fantasies encroach upon her external reality?

Sex Differences in the Sustained Effects of Ketamine on Resilience to Chronic Stress.

Exposure to stress is recognized to be a triggering factor in several mood disorders, including depression and anxiety. There is very little understanding of why female subjects have a significantly higher risk for these conditions than males. Recent findings in male rodents indicated that prophylactic ketamine can prevent the development of a stress-induced depressive-like phenotype, providing a pharmacological tool to study the mechanisms underlying stress resilience. Unfortunately, none of these studies incorporated female subjects, nor did they provide a mechanistic understanding of the effects of ketamine on stress resilience. Our previous work identified the prefrontal glutamatergic and parvalbumin (PV) systems as potential molecular mechanisms underlying sex differences in susceptibility to stress-induced emotional deregulations. To further address this point, we treated male and female mice with a single dose of ketamine before exposure to a chronic stress paradigm to determine whether stress-resilience induced by a pre-exposure to ketamine is similar in males and females and whether modulation of the prefrontal glutamatergic and PV systems by ketamine is associated with these behavioral effects. Ketamine prevented chronic stress-induced changes in behaviors in males, which was associated with a reduction in expression of PV and the NMDA receptor NR1 subunit. Ketamine did not protect females against the effects of chronic stress and did not change significantly prefrontal gene expression. Our data highlight fundamental sex differences in the sustained effects of ketamine. They also further implicate prefrontal glutamatergic transmission and PV in resilience to chronic stress.

Age Advantages in Emotional Experience Persist Even Under Threat From the COVID-19 Pandemic.

The COVID-19 pandemic is creating unprecedented, sustained, and unavoidable stress for the entire population, and older people are facing particularly heightened risk of contracting the virus and suffering severe complications, including death. The present study was conducted when the pandemic was spreading exponentially in the United States. To address important theoretical questions about age differences in emotional experience in times of crisis, we surveyed a representative sample of 945 Americans between the ages of 18 and 76 years and assessed the frequency and intensity of a range of positive and negative emotions. We also assessed perceived risk of contagion and complications from the virus, as well as personality, health, and demographic characteristics. Age was associated with relatively greater emotional well-being both when analyses did and did not control for perceived risk and other covariates. The present findings extend previous research about age and emotion by demonstrating that older adults' relatively better emotional well-being persists even in the face of prolonged stress.

Psychological impact of COVID-19 in the Swedish population: Depression, anxiety, and insomnia and their associations to risk and vulnerability factors.

BACKGROUND: The 2019 coronavirus disease (COVID-19) pandemic, with its associated restrictions on daily life, is like a perfect storm for poor mental health and wellbeing. The purpose of this study was therefore to examine the impacts of COVID-19 on mental health and wellbeing during the ongoing pandemic in Sweden. METHOD: Standardized measures of depression, anxiety, and insomnia as well as measures of risk and vulnerability factors known to be associated with poor mental health outcomes were administered through a national, online, cross-sectional survey (n = 1,212; mean age 36.1 years; 73% women). RESULT: Our findings show significant levels of depression, anxiety, and insomnia in Sweden, at rates of 30%, 24.2%, and 38%, respectively. The strongest predictors of these outcomes included poor self-rated overall health and a history of mental health problems. The presence of COVID-19 symptoms and specific health and financial worries related to the pandemic also appeared important. CONCLUSIONS: The impacts of COVID-19 on mental health in Sweden are comparable to impacts shown in previous studies in Italy and China. Importantly, the pandemic seems to impose most on the mental health of those already burdened with the impacts of mental health problems. These results provide a basis for providing more support for vulnerable groups, and for developing psychological interventions suited to the ongoing pandemic and for similar events in the future.

Predicting stress resilience and vulnerability: brain-derived neurotrophic factor and rapid eye movement sleep as potential biomarkers of individual stress responses.

STUDY OBJECTIVES: To examine the rapid eye movement sleep (REM) response to mild stress as a predictor of the REM response to intense stress and brain-derived neurotrophic factor (BDNF) as a potential biomarker of stress resilience and vulnerability. METHODS: Outbred Wistar rats were surgically implanted with electrodes for recording electroencephalography (EEG) and electromyogram (EMG) and intraperitoneal Data loggers to record body temperature. Blood was also obtained to measure circulating BDNF. After recovery, rats were exposed to mild stress (novel chamber, NC) and later intense stress (shock training, ST), followed by sleep recording. Subsequently, rats were separated into resilient (Res; n=27) or vulnerable (Vul; n = 15) based on whether or not there was a 50% or greater decrease in REM after ST compared to baseline. We then compared sleep, freezing, and the stress response (stress-induced hyperthermia, SIH) across groups to determine the effects of mild and intense stress to determine if BDNF was predictive of the REM response. RESULTS: REM totals in the first 4 hours of sleep after exposure to NC predicted REM responses following ST with resilient animals having higher REM and vulnerable animals having lower REM. Resilient rats had significantly higher baseline peripheral BDNF compared to vulnerable rats. CONCLUSIONS: These results show that outbred rats display significant differences in post-stress sleep and peripheral BDNF identifying these factors as potential markers of resilience and vulnerability prior to traumatic stress.

Hydrological hazards in Vhembe district in Limpopo Province, South Africa.

This study determined the risks associated with hydrological hazards and vulnerabilities to communities in Vhembe District Municipality, Limpopo province. Risk and vulnerability contribute to poverty, loss of lives and property, environmental and infrastructural destruction, food insecurity and unavailability of water resources. Streamflow and rainfall data were analysed using Log-Pearson Type III distribution and Standardised Precipitation Index (SPI), respectively, to identify return periods and probabilities of occurrence of floods and droughts. Mann-Kendall test was applied to identify trends of floods and droughts. Risk ratings were used to determine risks and vulnerabilities associated with floods and droughts. Standardised Precipitation Index analysis showed that a mild dryness condition dominated dry years in all stations with a range of 22.4% to 59.2% of the years falling within this category. Twenty-five per cent and 75% of rainfall stations depicted downward and upward trends, respectively. Equal number of streamflow stations depicted downward and upward trends. Results generally showed that flood events with return periods of 50, 100 and 200 years are mostly associated with significant and catastrophic consequence levels. This demonstrated high risk and vulnerability of the communities to these hazards. The findings of this study will aid in future planning and development of mitigation strategies associated with hydrological hazards.

Mapping Socioeconomic Exposure for Flood Risk Assessment in Italy.

Detailed spatial representation of socioeconomic exposure and the related vulnerability to natural hazards has the potential to improve the quality and reliability of risk assessment outputs. We apply a spatially weighted dasymetric approach based on multiple ancillary data to downscale important socioeconomic variables and produce a grid data set for Italy that contains multilayered information about physical exposure, population, gross domestic product, and social vulnerability. We test the performances of our dasymetric approach compared to other spatial interpolation methods. Next, we combine the grid data set with flood hazard estimates to exemplify an application for the purpose of risk assessment.

Global Spread of Hemorrhagic Fever Viruses: Predicting Pandemics.

As successive epidemics have swept the world, the scientific community has quickly learned from them about the emergence and transmission of communicable diseases. Epidemics usually occur when health systems are unprepared. During an unexpected epidemic, health authorities engage in damage control, fear drives action, and the desire to understand the threat is greatest. As humanity recovers, policy-makers seek scientific expertise to improve their "preparedness" to face future events.Global spread of disease is exemplified by the spread of yellow fever from Africa to the Americas, by the spread of dengue fever through transcontinental migration of mosquitos, by the relentless influenza virus pandemics, and, most recently, by the unexpected emergence of Ebola virus, spread by motorbike and long haul carriers. Other pathogens that are remarkable for their epidemic expansions include the arenavirus hemorrhagic fevers and hantavirus diseases carried by rodents over great geographic distances and the arthropod-borne viruses (West Nile, chikungunya and Zika) enabled by ecology and vector adaptations. Did we learn from the past epidemics? Are we prepared for the worst?The ultimate goal is to develop a resilient global health infrastructure. Besides acquiring treatments, vaccines, and other preventive medicine, bio-surveillance is critical to preventing disease emergence and to counteracting its spread. So far, only the western hemisphere has a large and established monitoring system; however, diseases continue to emerge sporadically, in particular in Southeast Asia and South America, illuminating the imperfections of our surveillance. Epidemics destabilize fragile governments, ravage the most vulnerable populations, and threaten the global community.Pandemic risk calculations employ new technologies like computerized maintenance of geographical and historical datasets, Geographic Information Systems (GIS), Next Generation sequencing, and Metagenomics to trace the molecular changes in pathogens during their emergence, and mathematical models to assess risk. Predictions help to pinpoint the hot spots of emergence, the populations at risk, and the pathogens under genetic evolution. Preparedness anticipates the risks, the needs of the population, the capacities of infrastructure, the sources of emergency funding, and finally, the international partnerships needed to manage a disaster before it occurs. At present, the world is in an intermediate phase of trying to reduce health disparities despite exponential population growth, political conflicts, migration, global trade, urbanization, and major environmental changes due to global warming. For the sake of humanity, we must focus on developing the necessary capacities for health surveillance, epidemic preparedness, and pandemic response.

Young women with disabilities and access to HIV/AIDS interventions in Uganda.

Sexual health and autonomy, and the often violent ways in which these are suppressed, are critical women's human rights issues. The process of ensuring that women enjoy their sexual and reproductive rights, including sexual health and freedom from HIV, is particularly challenging for persons with disabilities and most especially women with disabilities. This paper applies a human rights and gender lens to the sexuality and HIV-related vulnerabilities of young women with disabilities in Uganda. Widespread misperceptions about the sexual behaviours of women with disabilities, exposure to violence and exclusion from health promotion activities and health services, render women with disabilities, particularly young women with disabilities, disproportionately vulnerable to HIV and impede the full realisation of their sexual and reproductive health and rights. While limited protections exist for people with disabilities in Uganda, and some efforts have been made to provide appropriate services, the availability, accessibility, acceptability and quality of health services for this population group remains low, with a deleterious impact on their health and rights. This article calls for measures that strengthen the ability of young women with disabilities to prevent HIV infection and that promote responsiveness of the health system (as well as services in other sectors) to the sexual and reproductive health needs of this population.

The emotional impact of national music on young and older adults differing in posttraumatic stress disorder symptoms.

In spite of previous evidence regarding the function of national songs as a contextual stimulus, their effect on the emotional state of older adults living with different levels of posttraumatic stress disorder (PTSD) symptoms has not be been examined. Following the 2014 Israel-Gaza conflict, we examined the emotional effects of listening to happy national songs (songs of Independence Day) and sad national songs (Memorial Day songs) on young (N = 144, mean age = 29.4) and older adults (N = 132, mean age = 68.5). Respondents were exposed to happy or sad national songs, and completed measures of exposure to missile attacks, related PTSD symptoms, and positive and negative emotions. Sad national songs were related to higher negative affect among young adults who were lower on PTSD symptoms, but not among their older counterparts. In contrast, sad national songs were related to higher negative affect among older adults who were higher on PTSD symptoms, but not among their young counterparts. These findings support the strength and vulnerability model, as they demonstrate that relative to young adults, older adults are generally more capable to withstand negative stimuli, yet are more sensitive to negative stimuli when they suffer from chronic vulnerability, as in the case of higher level of PTSD symptoms.