AA, Bill Wilson, Carl Jung and LSD.

Alcoholics Anonymous (AA) is an established resource for people suffering from alcohol use disorder (AUD). However, Bill Wilson, the co-founder of AA, in his second letter to Jung referred to its low success rate. One evidence-based alternative, dating back to the 1950s, is the clinical use of lysergic acid diethylamide (LSD) for treating AUD. Bill Wilson was a strong advocate of using LSD as a preparation for alcoholics who had difficulty grasping the spiritual aspect of the 12-step programme. Bill Wilson wrote a "secret" four-page letter to Carl Jung detailing his own use of LSD and the success two psychiatrists in Canada had in treating alcoholics and asked for his advice on using LSD to help alcoholics. Aniela Jaffé, a Jungian analyst and co-worker of Jung, replied to Wilson on May 29, 1961, "… as soon as Dr. Jung feels better and has enough strength to begin again his mail, I will show it to him." Jung died a week later. This article quotes Jung's previous hostile opinions on psychedelics and asks: Just as Jung overcame his negative views on groups when giving "complete instructions" on extending the 12-step programme of AA to "general neurotics", might he similarly have changed his mind when he saw the documented success of using LSD with recalcitrant alcoholics?

Alcooliques Anonymes (A.A.) est une ressource reconnue pour les personnes souffrant du Trouble de l'Usage de l'Alcool (TUA). Bill Wilson, co­fondateur des AA, dans sa deuxième lettre à Jung, a fait référence à son faible taux de réussite. Une alternative fondée sur des preuves, et qui remonte aux années 1950, est l'utilisation médicale de l'acide lysergique diéthylamide (LSD) pour le traitement du TUA. Bill Wilson a fortement préconisé l'utilisation du LSD pour la préparation des alcooliques qui avaient des difficultés à saisir l'aspect spirituel du programme en douze étapes. Bill Wilson écrivit à Carl Jung une lettre de quatre pages, « secrète ¼, exposant en détails sa propre utilisation du LSD et le succès de deux psychiatres canadiens dans le traitement de personnes alcooliques avec le LSD. Il demandait conseil à Jung sur l'utilisation du LSD pour aider les alcooliques. Aniela Jaffé, une analyste jungienne et collaboratrice de Jung répondit à Wilson le 29 mai 1961 : « … dès que le Dr Jung se sentira mieux et aura suffisamment de force pour recommencer à s'occuper de son courrier, je lui montrerai. ¼ Jung est mort une semaine plus tard. Cet article cite les opinions antérieures négatives de Jung concernant les drogues psychédéliques et pose la question suivante: tout comme Jung avait dépassé ses perspectives négatives sur les groupes en donnant des « instructions complète ¼ sur l'extension du programme en douze étapes pour les « névrosés de base ¼, aurait­il de la même manière changé d'avis s'il avait vu les résultats probants de l'utilisation du LSD avec les alcooliques récalcitrants?

Alcohólicos Anónimos (A.A.) es un recurso establecido para las personas que padecen Trastorno por Consumo de Alcohol (AUD). Sin embargo, Bill Wilson, cofundador de AA, en su segunda carta a Jung se refirió a su baja tasa de éxito. Una alternativa basada en la evidencia, que se remonta a la década de 1950, es el uso clínico de la dietilamida del ácido lisérgico (LSD) para tratar el AUD. Bill Wilson era un firme defensor del uso del LSD como preparación para los alcohólicos que tenían dificultades para captar el aspecto espiritual del programa de 12 pasos. Bill Wilson escribió una carta "secreta" de cuatro páginas a Carl Jung en la que detallaba su propio uso del LSD y el éxito que habían tenido dos psiquiatras en Canadá en el tratamiento de alcohólicos con LSD y le pedía consejo a Jung sobre el uso del LSD para ayudar a los alcohólicos. Aniela Jaffé, analista Junguiana y compañera de trabajo de Jung, respondió a Wilson el 29 de mayo de 1961: "…tan pronto como el Dr. Jung se sienta mejor y tenga fuerzas suficientes para mirar de nuevo su correo, se lo mostraré". Jung murió una semana después. Este artículo cita las anteriores opiniones hostiles de Jung sobre los psicodélicos y pregunta: Del mismo modo que Jung superó sus opiniones negativas sobre los grupos al dar "instrucciones completas" sobre la extensión del programa de 12 pasos de A.A. a los "neuróticos en general", ¿podría haber cambiado de opinión de forma similar cuando vio el éxito documentado del uso del LSD con alcohólicos recalcitrantes?

Alcohol consumption in elderly people. What is the real magnitude of the problem?

The harmful effects of alcohol consumption have been well studied in the general population, but in the group of people over 80 years of age there is not much information regarding its relevance. It is estimated than 30%-40% of this population consumes alcohol regularly and around 10% engage in high-risk consumption. Furthermore, potential interactions between this substance and commonly consumed drugs in this age group, like oral antidiabetics, anticoagulants and antibiotics, may pose a risk of serious complications. In this sense, the aim of the present work was to analyze the magnitude of alcohol consumption within people over 80 years of age and the impact it has on their health. A narrative review of the available literature on the topic was carried out, which showed that alcohol consumption in people over 80 years of age is common in our environment and is associated with multiple complications and the development of different pathologies. The correct quantification of alcohol consumption in very elderly people must be integrated into the daily clinical practice of Medicine in general and Internal Medicine in particular.

Alcohol use among children and adolescents with chronic pain. Scoping review.

AIM: To examine and map alcohol consumption in children and adolescents with chronic pain (CP). METHOD: A scoping review of international databases (CINAHL, WOS, PubMed, PsycINFO, Scopus, Embase, and MEDLINE) and grey literature was conducted between September 2022 and February 2023. Documents addressing the relationship between alcohol consumption and CP in children and adolescents, published in English and Spanish between 2012 and 2023, were included. Those papers with a population suffering from CP derived from neurodegenerative diseases, chronic infectious diseases or cognitive impairment were excluded. We assessed the level of evidence (LE) and the degree of recommendation (DR) of the studies included in accordance with the Scottish Intercollegiate Guidelines Network. Finally, 11 documents were considered out of the 479 reviewed. RESULTS: The relationship between substance consumption and CP in adolescents is a scarcely investigated topic. While there is a trend towards lower rates of alcohol consumption in youth with pain, there is evidence suggesting an association, particularly in cases of intense pain. The use of various substances, both legal and illegal, for pain management underscores the importance of comprehensively addressing this phenomenon in this population. CONCLUSIONS: Further research is needed to assess the relationship between alcohol consumption in children and adolescents with CP.

Asociación entre obesidad abdominal, consumo de alcohol y actividad física en universitarios panameños / Association between abdominal obesity, alcohol consumption and physical activity in Panamanian college students

Introducción. La obesidad abdominal es considerada un factor de riesgo de enfermedad cardiovascular y diabetes. El consumo excesivo episódico de alcohol y la inactividad física también son factores de riesgo comportamentales asociados a enfermedades no transmisibles. Objetivo: Analizar la asociación entre la obesidad abdominal, el consumo de alcohol y la inactividad física en universitarios panameños. Materiales y métodos: Estudio transversal analítico realizado en 374 estudiantes universitarios panameños en el periodo abril ­ diciembre de 2021. Se implementó el cuestionario para la vigilancia de factores de riesgo de enfermedades no transmisibles de la Organización Mundial de la Salud y se evaluó la circunferencia de cintura. La obesidad abdominal se estableció con una circunferencia de cintura ≥80 cm en mujeres y ≥90 cm en hombres. Se realizaron análisis descriptivos, bivariados y múltiples usando modelos de regresión logística para determinar la asociación entre las variables del estudio. Las pruebas U Mann-Whitney y Chi cuadrado fueron utilizadas para analizar diferencias por sexo. Resultados: Una tercera parte de los universitarios participantes presentaron obesidad abdominal. Las mujeres reportaron mayores niveles de inactividad física (<0,0001) y conducta sedentaria (p=0,0010) que los hombres. Después de ajustar por sexo, edad y nivel socioeconómico, la obesidad abdominal estuvo asociada con la inactividad física (OR: 1,762, IC 95%: 1,040 ­ 2,985, p=0,035) y el consumo excesivo episódico de alcohol (OR 1,114, IC: 1,015 ­ 1,223, p=0,023). Conclusiones: Los universitarios panameños que reportaron bajos niveles de actividad física y consumo excesivo episódico de alcohol tuvieron una mayor probabilidad de registrar obesidad abdominal(AU)

Introduction. Abdominal obesity is considered a risk factor for cardiovascular disease and diabetes. Episodic excessive consumption of alcohol and physical inactivity are behavioral risk factors associated with non-communicable diseases. Objective: To analyze the association between abdominal obesity, alcohol consumption and physical inactivity in Panamanian university students. Materials and methods: Analytical cross-sectional study conducted on 374 Panamanian university students in the period April ­ December 2021. The questionnaire for the surveillance of risk factors for non-communicable diseases of the World Health Organization was implemented and waist circumference was evaluated. Abdominal obesity was established with a waist circumference ≥80 cm in women and ≥90 cm in men. Descriptive, bivariate, and multiple analyzes were performed using logistic regression models to determine the association between the study variables. The Mann-Whitney U and Chi square tests were used to analyze differences by sex. Results: A third of the participating university students had abdominal obesity. Women reported higher levels of physical inactivity (<0,0001) and sedentary behavior (p=0,0010) than men. After adjusting for sex, age and socioeconomic status, abdominal obesity was associated with physical inactivity (OR: 1,762, 95% CI: 1,040 ­ 2,985, p=0,035) and episodic heavy alcohol consumption (OR 1,114, CI: 1,015 ­ 1,223, p=0,023). Conclusions: Students who reported low levels of physical inactivity and binge drinking were more likely to have abdominal obesity(AU)

Effect of the Mediterranean diet in cardiovascular prevention.

The Mediterranean diet is the best evidence-based model for cardiovascular prevention. In addition to 2 major randomized secondary prevention trials (Lyon Heart and CORDIOPREV) and 1 primary prevention trial (PREDIMED) that have demonstrated these benefits, there is an unprecedented body of high-quality prospective epidemiological evidence supporting these beneficial effects. The key elements of this traditional pattern are the abundant use of extra-virgin olive oil and high consumption of foods of natural plant-based origin (fruits, vegetables, nuts, and legumes) and fish, along with a reduction in processed meats, red meats, and ultraprocessed products. Moderate consumption of wine, preferably red wine, with meals is an essential element of this traditional pattern. Although removing wine consumption from the Mediterranean diet has been associated with a reduction in its preventive efficacy, doubts have recently arisen about the possible adverse effect of even low or moderate intake of any alcoholic beverages. A new large Spanish trial, UNATI, which will begin in June 2024, will randomize 10 000 drinkers aged 50 to 75 years to abstention or moderate consumption. UNATI aims to answer these doubts with the best possible evidence.

Trend in mortality from mental and behavioral disorders due to alcohol use in Brazil, 2010-2021 / Tendencias de mortalidad por trastornos mentales y comportamentales relacionados con el consumo de alcohol en Brasil: 2010-2021 / Tendência da mortalidade por transtornos mentais e comportamentais devidos ao uso de álcool no Brasil, 2010-2021

Abstract Objective: To analyze the trend in mortality from mental and behavioral disorders due to alcohol use in Brazil, 2010-2021. Methods: This was an time series study using Mortality Information System data. Annual percentage change (APC) and 95% confidence intervals (95% CI) were calculated using Prais-Winsten linear regression. Results: Mortality showed a stationary trend for Brazil as a whole (APC = 0.6; 95%CI -4.2;3.0), a falling trend in individuals aged 20-29 years in the South (APC = -7.4; 95%CI -10.0;-4.3) and Northeast (APC = -3.4; 95%CI -6.4;-0.4) regions, in people aged 30-39 in the Midwest region (APC = -3,8; 95%CI -7.4;-0.1) and 40-49 in the South (APC = -2.1; 95%CI -3.8;-0.4), North (APC = -3.1; 95%CI -5.7;-0.5) and Midwest (APC = -2.9; 95%CI -5.5;-0.3) regions. Conclusion: Mortality from mental and behavioral disorders due to alcohol use showed a stationary trend nationally and a falling trend in some age groups regionally.

Resumen Objetivo: Analizar la tendencia de mortalidad por trastornos mentales y del comportamiento en decorrencia del consumo de alcohol en Brasil en el período 2010-2021. Métodos: Estudio de series de tiempo ecológicas, con datos del Sistema de Información de Mortalidad; el cambio porcentual anual (APV) y los respectivos intervalos de confianza del 95% (IC95%) se calcularon mediante regresión lineal de Prais-Winsten. Resultados: Hubo una tendencia estacionaria en la mortalidad en Brasil en su conjunto (VPA = 0,6; IC95% -4,2;3,0), una tendencia decreciente en individuos de 20 a 29 años en las regiones del Sur (VPA = -7,4; IC95% -10,0;-4,3) y Noreste (VPA = -3,4; IC95% -6,4;-0,4), en personas de 30 a 39 años en el Centro-Oeste (VPA = -3,8; IC95% -7,4;-0,1) y en adultos de 40 a 49 años en el Sur (VPA = -2,1; IC95% -3,8;-0,4), Norte (VPA = -3,1; IC95% -5,7;-0,5) y Centro-Oeste (VPA = - 2,9; IC95% -5,5;-0,3). Conclusión: La mortalidad por trastornos mentales y del comportamiento a causa del consumo de alcohol presentó una tendencia estacionaria en Brasil y una tendencia decreciente en algunos grupos etarios.

Resumo Objetivo: Analisar a tendência da mortalidade por transtornos mentais e comportamentais devidos ao uso de álcool no Brasil em 2010-2021. Métodos: Estudo de séries temporais, com dados do Sistema de Informação sobre Mortalidade. A variação percentual anual (VPA) e respectivos intervalos de confiança de 95% (IC95%) foram calculados por regressão linear de Prais-Winsten. Resultados: Houve tendência estacionária na mortalidade no Brasil como um todo (VPA = 0,6; IC95% -4,2;3,0), tendência decrescente em indivíduos de 20-29 anos nas regiões Sul (VPA = -7,4; IC95% -10,0;-4,3) e Nordeste (VPA = -3,4; IC95% -6,4;-0,4), em pessoas de 30-39 anos no Centro-Oeste (VPA = -3,8; IC95% -7,4;-0,1) e naqueles com 40-49 anos nas regiões Sul (VPA = -2,1; IC95% -3,8;-0,4), Norte (VPA = -3,1; IC95% -5,7;-0,5) e Centro-Oeste (VPA = -2,9; IC95% -5,5;-0,3). Conclusão: A mortalidade por transtornos mentais e comportamentais devidos ao uso de álcool apresentou tendência estacionária no Brasil e decrescente em algumas faixas etárias.

Teoría de Rango Medio: Factores personales, ambientales y consumo de alcohol / Middle Range Theory: Personal, environmental factors and alcohol consumption / Teoria do Médio Alcance: Fatores pessoais, ambientais e consumo de álcool

El consumo de alcohol se considera un fenómeno complejo y multifactorial que puede estudiarse a través de diversas posturas teóricas, sin embargo, algunas teorías existentes carecen de sufi-cientes elementos para explorar y comprender dicho fenómeno. Por lo anterior, se propone una Teoría de Rango Medio que aborde los factores personales, ambientales y representaciones so-ciales del consumo de alcohol en jóvenes universitarios a partir de la Teoría Cognitiva Social de Bandura y de la conceptualización de la representación social de Moscovici. Para ello, se utilizó el método de Estructura Conceptual-Teórico-Empírico propuesto por Fawcett, compuesto por cinco pasos. La teoría derivada de este método contribuye en la identificación de un fenómeno específico para la disciplina mediante la determinación de conceptos y su relación con el con-sumo de alcohol en jóvenes universitarios. Además, de la incorporación de las representaciones sociales como elemento innovador para la profundización del fenómeno. Esta propuesta puede ser considerada en futuras investigaciones para ser probada y contribuir significativamente en el desarrollo de conocimiento sobre el consumo de alcohol

Alcohol consumption is considered a complex and multifactorial phenomenon that can be studied through various theoretical positions; however, some existing theories lack sufficient elements to explore and understand this phenomenon. Therefore, a Middle Range Theory is proposed that addresses personal, environmental, and social representations of alcohol consumption in young university students based on Bandura's Social Cognitive Theory and Moscovici's conceptualiza-tion of social representation. For this, the method of Conceptual-Theoretical-Empirical Structure proposed by Fawcett was used, consisting of five steps. The theory derived from this method con-tributes to the identification of a specific phenomenon for the discipline by determining concepts and their relationship with alcohol consumption in young university students. In addition, the incorporation of social representations as an innovative element for the deepening of the phenom-enon. This proposal can be considered in future research to be tested and contribute significantly to the development of knowledge about alcohol consumption

O consumo de álcool é considerado um fenômeno complexo e multifatorial que pode ser estu-dado por meio de vários posicionamentos teóricos, porém, algumas teorias existentes carecem de elementos suficientes para explorar e compreender esse fenômeno. Assim, propõe-se uma Teoria de Médio Alcance que aborda as representações pessoais, ambientais e sociais do consu-mo de álcool em universitários com base na Teoria Social Cognitiva de Bandura e na conceitu-ação de representação social de Moscovici. Para isso, foi utilizado o método da Estrutura Con-ceitual-Teórico-Empírica proposto por Fawcett, composto por cinco etapas. A teoria derivada desse método contribui para a identificação de um fenômeno específico da disciplina ao deter-minar conceitos e sua relação com o consumo de álcool em jovens universitários. Além disso, a incorporação das representações sociais como elemento inovador para o aprofundamento do fenômeno. Essa proposta pode ser considerada em pesquisas futuras a serem testadas e contribuir significativamente para o desenvolvimento do conhecimento sobre o consumo de álcool

Prevalence of alcohol, tobacco, and illicit drugs consumption during teenage pregnancy: an observational, prospective, and cross-sectional study.

BACKGROUND: Teenage pregnancy is a significant public health issue in Mexico; its prevalence oscillates around 20% of all pregnancies. Concurrently, alcohol, tobacco, and illicit drug use have become more common in this age group. METHODS: To estimate the prevalence of substance exposure in a population of pregnant teenagers, we conducted a prospective, observational, and cross-sectional study. The protocol was approved by the institutional review board. On informed consent, we asked 420 consecutive pregnant youngsters cared for at the outpatient obstetric service of a tertiary public regional women's and children's hospital in Nuevo León, in northeast Mexico, to answer a previously validated questionnaire to estimate the prevalence of alcohol, tobacco, or illicit drugs use during pregnancy. RESULTS: Of the 420 participants, 317 (75.5%) consumed at least one substance during pregnancy. Alcohol, either alone or in combination, was consumed by 300 (71.7%) participants. Tobacco was used by 117 (27.8%) participants, almost always in combination with other substances, while marijuana and other illicit drugs were consumed by 92 (21.9%) participants. Approximately one-fourth of the participants, 102 (24.1%) reported no substance use during pregnancy. CONCLUSIONS: In this series, the reported prevalence of alcohol, tobacco, and illicit drugs consumption during pregnancy, explored with a validated instrument, is higher than that previously reported in our country. This fact offers a worrying picture of another set of factors adding to the burden of teenage pregnancy.

INTRODUCCIÓN: El embarazo en la adolescencia ha adquirido gran importancia en la salud pública en México; su prevalencia oscila alrededor del 20% de los embarazos. Paralelamente, el consumo de alcohol, tabaco y drogas ilícitas en este periodo es cada vez más común en estas jóvenes. MÉTODOS: Para estimar la prevalencia de exposición a estas substancias en adolescentes embarazadas, se llevó a cabo un estudio prospectivo, observacional y transversal. El protocolo fue aprobado por los Comités de Ética e Investigación. Previo consentimiento informado, se solicito a 420 jóvenes embarazadas atendidas en la clínica prenatal del hospital materno-infantil más grande en Nuevo León, que respondieran un cuestionario previamente validado para estimar la prevalencia del consumo de substancias. RESULTADOS: De 420 participantes, 317 (75.5%) consumieron al menos una de estas sustancias durante el embarazo. El alcohol, solo o en combinación, fue consumido por 300 (71.5%). El tabaco fue usado por 117 (27.8%), casi siempre en combinación con otras sustancias, mientras que la mariguana y otras drogas ilícitas fueron consumidas por 92 (21.9%) participantes. Alrededor de una cuarta parte del grupo estudiado (24.1%) reportó no haber consumido ninguna de estas substancias en su embarazo. CONCLUSIONES: En nuestra serie, la prevalencia de consumo de alcohol, tabaco y drogas ilícitas durante el embarazo, explorada con un instrumento validado, es mayor de la reportada en estimaciones previas en nuestro país. Estos datos ofrecen un panorama preocupante de una serie de factores que se agregan a la carga del embarazo en la adolescencia.

Consumo de substâncias psicoativas entre estudantes de medicina antes e depois do ingresso no curso / Use of psychoactive substances among medicine students before and after admission to course

Introdução: Substâncias psicoativas são capazes de alterar a consciência, o humor ou o pensamento de um indivíduo, resultando em mudanças fisiológicas ou de comportamento. Objetivo: Este estudo avaliou se houve diferença no consumo de 13 substâncias psicoativas por estudantes de medicina, de uma faculdade privada do interior paulista, antes e depois do ingresso no curso. Método: Um questionário estruturado e impresso foi apresentado a ingressantes no curso de medicina, em abril de 2019, e, novamente, em dezembro, ao final do primeiro ano da graduação. Resultados: Na análise dos dados, foi realizado o Teste de Wilcoxon, com o emprego do programa estatístico JASP. No total, 90 estudantes participaram do estudo. Dentre as 13 substâncias consideradas, apenas para o álcool foram encontradas evidências estatísticas que indicaram ter ocorrido um aumento significativo no consumo após o ingresso no curso (W = 1308,00, p < 0,001). Conclusão: A continuidade dos estudos sobre o uso de substâncias lícitas e ilícitas entre os estudantes da instituição de ensino considerada será fundamental para garantir um monitoramento contínuo. Desse modo, a instituição poderá identificar usos abusivos e implementar políticas de prevenção, garantindo o bem-estar de seus alunos

Introduction: Psychoactive substances are capable of altering an individual's consciousness, mood or thinking, resulting in physiological or behavioral changes. Objective: This study assessed whether there was a difference in the consumption of 13 psychoactive substances by medical students at a private college in the interior of São Paulo, before and after enrolling in the course. Method: A structured, printed questionnaire was presented to new medicine students in April 2019, and again in December, at the end of the first year of graduation. Results: In data analysis, the Wilcoxon Test was performed, using the JASP statistical program. In total, 90 students participated in the study. Among the 13 substances considered, only for alcohol was statistical evidence found that indicated that there had been a significant increase in consumption after enrolling in the course (W = 1308.00, p < 0.001). Conclusion: Continuing studies on the use of legal and illicit substances among students at the educational institution considered will be essential to ensure continuous monitoring. In this way, the institution will be able to identify abusive uses and implement prevention policies, ensuring the well-being of its students

Introducción: Las sustancias psicoactivas son capaces de alterar la conciencia, el estado de ánimo o el pensamiento de un individuo, resultando en cambios fisiológicos o de comportamiento. Objetivo: Este estudio evaluó si existía diferencia en el consumo de 13 sustancias psicoactivas por estudiantes de medicina de una facultad privada del interior de São Paulo, antes y después de matricularse en el curso. Método: Se presentó un cuestionario impreso estructurado a los nuevos estudiantes de medicina en abril de 2019, y nuevamente en diciembre, al final del primer año de graduación. Resultados: En el análisis de los datos se realizó la Prueba de Wilcoxon, utilizando el programa estadístico JASP. En total, 90 estudiantes participaron en el estudio. Entre las 13 sustancias consideradas, sólo para el alcohol se encontró evidencia estadística que indicaba que había habido un aumento significativo en el consumo después de la inscripción al curso (W = 1308,00, p < 0,001). Conclusión: Continuar con los estudios sobre el uso de sustancias legales e ilícitas entre los estudiantes de la institución educativa considerada será fundamental para garantizar un seguimiento continuo. De esta manera, la institución podrá identificar usos abusivos e implementar políticas de prevención, asegurando el bienestar de sus estudiantes

Traducción, adaptación cultural y validación de la Escala de Apoyo a Políticas Asociadas al Alcohol en universitarios mexicanos / Tradução, adaptação cultural e validação da Escala de Apoio a Políticas Associadas ao Álcool em universitários mexicanos / Translation, cultural adaptation, and validation of the Support for Public Policies to Reduce Alcohol-Related Problems Scale among Mexican university students

Resumen Marco contextual: La protección de la salud por medio de la prevención y la reducción del consumo de alcohol es una prioridad para la salud pública. Se han identificado algunas escalas para evaluar políticas públicas de alcohol, pero en idioma inglés. Objetivo: Evaluar las propiedades psicométricas de la traducción y adaptación cultural de una escala para evaluar el apoyo a políticas de alcohol en jóvenes universitarios mexicanos. Metodología: Estudio metodológico, con la participación de 367 estudiantes universitarios del sur de México. La validez del constructo se estimó mediante un análisis factorial exploratorio y se verificó la consistencia interna del cuestionario para comprobar su fiabilidad. Resultados: La consistencia interna fue de 0.96. La validez de constructo se realizó mediante el análisis factorial exploratorio y se identificó una estructura de tres factores: la reducción del daño, el mercadeo e información, y el precio y la disponibilidad. Conclusión: La escala mostró fiabilidad y validez adecuada, y puede ser aplicada en español como indicador empírico en estudios referentes a las políticas públicas de alcohol en jóvenes universitarios.

Abstract Background: Health protection through prevention and reduction of alcohol consumption is a public health priority. Some scales have been identified to assess public alcohol policies but in English language. Objective: To evaluate the psychometric properties of the translation and cultural adaptation of a scale to assess support for alcohol policies in young Mexican university students. Methodology: Methodological study, with the participation of 367 university students from southern Mexico. Construct validity was estimated by means of an exploratory factor analysis and the internal consistency of the questionnaire was checked to verify its reliability. Results: Internal consistency was 0.96. Construct validity was performed through exploratory factor analysis, identifying a three factors structure: harm reduction, marketing and information, and price and availability. Conclusion: The scale showed adequate reliability and validity, and can be applied in Spanish as an empirical indicator in studies concerning alcohol public policies in young university students.

Resumo Enquadramento: A proteção da saúde através da prevenção e redução do consumo de álcool é uma prioridade de saúde pública. Foram identificadas algumas escalas para avaliar as políticas públicas em matéria de álcool, mas em língua inglesa. Objetivo: Avaliar as propriedades psicométricas da tradução e adaptação cultural de uma escala para avaliar o apoio às políticas sobre o álcool em jovens estudantes universitários mexicanos. Metodologia: Estudo metodológico, com a participação de 367 estudantes universitários do sul do México. A validade do constructo foi estimada através de uma análise exploratória dos fatores e a consistência interna do questionário foi verificada para verificar a sua fiabilidade. Resultados: A consistência interna foi de 0,96. A validade de constructo foi realizada por médio de análise fatorial exploratória, identificando uma estrutura de três fatores: redução de danos, marketing e informação, e preço e disponibilidade. Conclusão: A escala mostrou fiabilidade e validade adequadas, e pode ser aplicada em espanhol como um indicador empírico em estudos relativos a políticas públicas sobre o álcool em jovens estudantes universitários.

Prevalence of alcohol, tobacco, and illicit drugs consumption during teenage pregnancy: an observational, prospective, and cross-sectional study / Prevalencia del consumo de alcohol, tabaco y drogas ilícitas durante el embarazo en adolescentes: un estudio observacional, prospectivo y transversal

Abstract Background: Teenage pregnancy is a significant public health issue in Mexico; its prevalence oscillates around 20% of all pregnancies. Concurrently, alcohol, tobacco, and illicit drug use have become more common in this age group. Methods: To estimate the prevalence of substance exposure in a population of pregnant teenagers, we conducted a prospective, observational, and cross-sectional study. The protocol was approved by the institutional review board. On informed consent, we asked 420 consecutive pregnant youngsters cared for at the outpatient obstetric service of a tertiary public regional women´s and children´s hospital in Nuevo León, in northeast Mexico, to answer a previously validated questionnaire to estimate the prevalence of alcohol, tobacco, or illicit drugs use during pregnancy. Results: Of the 420 participants, 317 (75.5%) consumed at least one substance during pregnancy. Alcohol, either alone or in combination, was consumed by 300 (71.7%) participants. Tobacco was used by 117 (27.8%) participants, almost always in combination with other substances, while marijuana and other illicit drugs were consumed by 92 (21.9%) participants. Approximately one-fourth of the participants, 102 (24.1%) reported no substance use during pregnancy. Conclusions: In this series, the reported prevalence of alcohol, tobacco, and illicit drugs consumption during pregnancy, explored with a validated instrument, is higher than that previously reported in our country. This fact offers a worrying picture of another set of factors adding to the burden of teenage pregnancy.

Resumen Introducción: El embarazo en la adolescencia ha adquirido gran importancia en la salud pública en México; su prevalencia oscila alrededor del 20% de los embarazos. Paralelamente, el consumo de alcohol, tabaco y drogas ilícitas en este periodo es cada vez más común en estas jóvenes. Métodos: Para estimar la prevalencia de exposición a estas substancias en adolescentes embarazadas, se llevó a cabo un estudio prospectivo, observacional y transversal. El protocolo fue aprobado por los Comités de Ética e Investigación. Previo consentimiento informado, se solicito a 420 jóvenes embarazadas atendidas en la clínica prenatal del hospital materno-infantil más grande en Nuevo León, que respondieran un cuestionario previamente validado para estimar la prevalencia del consumo de substancias. Resultados: De 420 participantes, 317 (75.5%) consumieron al menos una de estas sustancias durante el embarazo. El alcohol, solo o en combinación, fue consumido por 300 (71.5%). El tabaco fue usado por 117 (27.8%), casi siempre en combinación con otras sustancias, mientras que la mariguana y otras drogas ilícitas fueron consumidas por 92 (21.9%) participantes. Alrededor de una cuarta parte del grupo estudiado (24.1%) reportó no haber consumido ninguna de estas substancias en su embarazo. Conclusiones: En nuestra serie, la prevalencia de consumo de alcohol, tabaco y drogas ilícitas durante el embarazo, explorada con un instrumento validado, es mayor de la reportada en estimaciones previas en nuestro país. Estos datos ofrecen un panorama preocupante de una serie de factores que se agregan a la carga del embarazo en la adolescencia.

La carga de la enfermedad por cirrosis hepática en México / Burden of disease due to liver cirrhosis in Mexico

Resumen Antecedentes: La cirrosis hepática es una causa importante de morbilidad y mortalidad en el mundo. En México, constituye una las primeras seis causas de muerte. Objetivo: Analizar los datos epidemiológicos derivados del estudio de Global Burden of Disease y su relación con los factores de riesgo asociados al desarrollo de hepatopatías crónicas en México. Material y métodos: Se realizó el análisis de datos provenientes del Instituto para la Medición y Evaluación de la Salud y del Instituto Nacional de Estadística y Geografía. Resultados: La cirrosis hepática tiene una prevalencia alta en México, con una carga de enfermedad importante traducida en años perdidos de vida saludable, por muerte prematura y por discapacidad. La mortalidad por cirrosis ocupó el sexto lugar (3.6 %) en 2021 y fue la octava causa de años de vida saludable perdidos (2.8 %). De 1990 a 2021, la tasa de mortalidad se incrementó de 26.7 a 34.2 por 100 000 habitantes. Conclusiones: La carga de enfermedad por cirrosis hepática se continúa derivando del consumo de alcohol y de la hepatitis C; la prevalencia de la cirrosis causada por enfermedad hepática esteatósica se ha incrementado en la última década. Existen cambios epidemiológicos en la frecuencia y carga de la hepatopatía crónica que muestra variaciones territoriales en México.

Abstract Background: Liver cirrhosis is a major cause of morbidity and mortality worldwide. In Mexico, it is one of the six leading causes of death. Objective: To analyze epidemiological data derived from the Global Burden of Disease study and their relationship with risk factors associated with the development of chronic liver diseases in Mexico. Material and methods: An analysis of data from the Institute for Health Metrics and Evaluation and the National Institute of Geography and Statistics was carried out. Results: Liver cirrhosis has a high prevalence in Mexico, with significant burden of disease translating into lost years of healthy life, premature death and disability. Mortality due to cirrhosis ranked sixth (3.6%) in 2021 and was the eighth cause of years of healthy life lost (2.8%). From 1990 to 2021, the mortality rate increased from 26.7 to 34.2 per 100,000 population. Conclusions: The burden of disease due to liver cirrhosis continues to be caused by alcohol consumption and hepatitis C; cirrhosis caused by steatotic liver disease has increased in terms of prevalence over the past decade. There are epidemiological changes in the frequency and burden of chronic liver disease that show territorial variations in Mexico.

Intención de consumo de alcohol en adolescentes que cursan estudios en la enseñanza técnica profesional

Introducción: El consumo excesivo de bebidas alcohólicas por los adolescentes, constituye un problema de salud emergente, cuya solución ha devenido en prioridad mundial. El determinante inmediato para la ejecución de una conducta es la intención del individuo, por lo que es un momento preciso para aplicar acciones preventivas. Objetivos: Explorar la intención de consumo de alcohol y su relación con variables sociodemográficas y de consumo. Métodos: Se realizó un estudio descriptivo de corte transversal, con 143 adolescentes entre 15 y 18 años de edad, seleccionados mediante un muestreo aleatorio simple. Se les aplicó el cuestionario de intención de uso de alcohol. Resultados: El 84,6 % de los adolescentes había consumido alcohol; el 45,5 % tenía 18 años de edad y el 57,9 % eran varones. La edad de inicio del consumo fue de 15 años para el 41,3 %. El puntaje medio en la escala actitud fue mayor, de forma significativa, en los consumidores (p= 0,000). La actitud es la dimensión que más contribuyó a la iniciación en el consumo de alcohol (Wald= 14,56; p= 0,000). Conclusiones: Los adolescentes se caracterizan por ser en su mayoría consumidores de bebidas alcohólicas, con predominio del sexo masculino y una edad promedio de inicio del consumo de 15 años. La variable fundamental favorecedora de la intención de consumo de alcohol es la actitud positiva hacia el consumo, frecuentemente reforzada en el ambiente social y familiar.

Introduction: Excessive consumption of alcoholic beverages by adolescents, constitutes an emerging health problem, whose solution has become a global priority. The immediate determinant for the execution of a behavior is the intention of the individual, so it is a precise moment to apply preventive actions. Objectives: To explore the intention to consume alcohol and its relationship with sociodemographic and consumption variables. Methods: A descriptive cross-sectional study was carried out with 143 adolescents between 15 and 18 years of age, selected by simple random sampling. They were administered the alcohol use intention questionnaire. Results: 84.6% of the adolescents had consumed alcohol; 45.5% were 18 years old and 57.9% were male. The age of onset of consumption was 15 years for 41.3%. The mean score on the attitude scale was significantly higher in consumers (p= 0.000). Attitude is the dimension that contributed most to the initiation of alcohol consumption (Wald= 14.56; p= 0.000). Conclusions: Adolescents are characterized by being mostly consumers of alcoholic beverages, with a predominance of male sex and an average age of onset of consumption of 15 years. The fundamental variable favoring the intention to consume alcohol is the positive attitude towards consumption, frequently reinforced in the social and family environment.

Urban and social determinants of alcohol and tobacco consumption among adolescents in Madrid.

OBJECTIVE: This study aims to describe the accessibility to and promotion of alcohol and tobacco around secondary schools in Madrid and its distribution in relation with area-level socioeconomic deprivation; analyze the relationship between this exposure and individual consumption characteristics of students between 14 and 18 years old; and explore other facilitators of this consumption. METHOD: Mixed-methods study conducted in three phases: 1) we collected data on accessibility to and promotion of alcohol and tobacco in the environment using systematic social observation around 55 secondary schools; 2) we administered 2287 questionnaires among the students in these centers to gather information about characteristics and determinants of consumption; and 3) we conducted 20 semi-structured interviews and one discussion group to deepen in the results obtained in surveys and systematic social observation. We will use Geographic Information Systems to integrate and analyze the data from a spatial perspective.

Prevalence of increased alcohol use and alcohol use disorders in adult victims of terrorist attacks: a systematic and meta-analytic review.

Background: Previous studies have reviewed the evidence on the increase in alcohol consumption after a terrorist attack. However, an increase does not necessarily imply the presence of an alcohol use disorder.Objectives: To conduct a systematic and meta-analytic review of the literature on the prevalence of increased alcohol consumption and alcohol use disorders in adult exposed to terrorism.Methods: A search of PsycINFO, MEDLINE and PTSDpubs identified 29 studies published up to March 2023 in which 38 adult samples totaling 282,753 persons exposed to terrorism were assessed. Using inverse variance heterogeneity models, pooled prevalence rates of increased alcohol use and alcohol use disorders were calculated.Results: 6% (95% CI [2.9, 9.5]) of the adults exposed to a terrorist attack increased their alcohol consumption. The prevalence of increased alcohol use varied depending on the degree of exposure (p = .006, R2 = .18) and the procedure for measuring increases (p = .043, R2 = .37). The prevalence of alcohol use disorders in adults exposed to a terrorist attack was 5.5% (95% CI [3.7, 7.5]), a rate that was not higher than that obtained in the general population and varied depending on the type of alcohol disorder (p = .015, R2 = .30).Conclusions: A relevant number of adults exposed to terrorist attacks will subsequently increase their alcohol consumption, but this increase is not associated with an increase in the prevalence of alcohol use disorders. Effects of terrorism on people's health are potentially widespread, but concerns of excessive alcohol use after terrorist attacks may be unwarranted.

Fidelity of implementation of Reptes, an alcohol and cannabis selective prevention program for youngsters.

OBJECTIVE: Implementation fidelity is a key dimension in process evaluation but has been scarcely studied. Reptes is a selective alcohol and cannabis use prevention program performed in vulnerable young people (16-21 years) from different educational and leisure settings. The study aimed to describe the components of this program, its implementation fidelity, and satisfaction among participants and facilitators. METHOD: A descriptive cross-sectional study was conducted. Implementation fidelity was assessed in terms of adherence, dose, participant responsiveness, and quality of the intervention through self-reports completed by 15 facilitators and self-administered questionnaires by 99 youth from the 15 groups completing the program. RESULTS: 70.7% of the groups performed 30 of the 43 planned activities with high use of various teaching methods, except for Information and Communication Technology resources. Fidelity implementation was above 70%. 2/3 groups completed an acceptable intervention and 1/3 completed a qualified intervention. Satisfaction was higher than 7. CONCLUSIONS: Our results show high implementation fidelity and satisfaction compared with those from similar studies.

Motivos para el consumo de tabaco, alcohol y cannabis en el contexto del confinamiento por COVID-19 / Motives for tobacco, alcohol, and cannabis use in the confinement context due to COVID-19 pandemic

Introducción. Las drogas producen importantes consecuencias negativas en las sociedades. La prevalencia de su consumo sigue aumentando debido a que existen diversos motivos que acercan a las personas a consumirlas. Objetivo. Identificar las diferencias en la frecuencia y cantidad del consumo de tabaco, alcohol y cannabis durante y después del confinamiento por la pandemia de COVID-19; así como la influencia del confinamiento en los motivos y los riesgos de desarrollar un consumo problemático. Metodología. Estudio transversal analítico con muestreo no probabilístico en dos momentos. Participaron 520 jóvenes: 246 estudiantes de bachillerato y universidad en el año 2020, durante el confinamiento y 274, en 2022. Se evaluaron datos sociodemográficos, motivos de consumo y consumo problemático. Resultados. El consumo de cannabis durante el confinamiento (41,1 %) fue mayor que en el posconfinamiento (29,6 %; p 0,006). Hubo diferencias entre los grupos de consumo problemático de tabaco durante el confinamiento y los motivos sociales (W 8,178, p 0,017) y de afrontamiento (W 26,456, p < 0,001); también, entre los grupos de consumo problemático de alcohol y los motivos sociales (W 6865,5, p < 0,001); de animación (W 6768,0, p < 0,001); de afrontamiento (W 6176,0, p = 0,002) y de expansión (W 6774,0, p < 0,001). Entre los motivos del consumo problemático de cannabis se destacan los sociales (W 6,404, p 0,041); de animación (W 9,409, p 0,009); de afrontamiento (W 9,265, p 0,010) y de expansión (W 27,692, p < 0,001). Conclusión. El confinamiento incrementó el riesgo de consumir tabaco y cannabis. Los motivos de consumo también aumentaron, excepto las asociadas al consumo de alcohol en universitarios. El consumo problemático de tabaco estuvo motivado por necesidades sociales y de afrontamiento; el de alcohol y cannabis, por necesidades sociales, de animación, de afrontamiento y de expansión

Introduction. Drugs produce significant negative consequences in societies. The prevalence of drug use continues to increase because various reasons lead people to use them. Objective. Identify differences in the frequency and amount of tobacco, alcohol, and cannabis use during and after COVID-19 pandemic confinement, the influence of confinement on motives, and risks for developing problematic use. Methodology. Analytical cross-sectional study with non-probabilistic sampling at two points in time. Five hundred and twenty young people participated: 246 high school and university students during the confinement in 2020, and 274 in 2022. Sociodemographic data, reasons for consumption, and problematic consumption were evaluated. Results. Cannabis use during confinement (41.1 %) was higher than post-confinement (29.6 %; p 0.006). There were differences between the groups of problematic tobacco use during confinement and the social (W 8.178, p 0.017), and coping (W 26.456, p < 0.001) motives; also, between the groups of problematic alcohol consumption and social motives (W 6865.5, p < 0.001); encouragement (W 6768.0, p < 0.001); coping (W 6176.0, p = 0.002) and expansion (W 6774.0, p < 0.001). Among the motives for problematic cannabis use, social (W 6.404, p 0.041); animation (W 9.409, p 0.009); coping (W 9.265, p 0.010), and expansion (W 27.692, p < 0.001) were highlighted. Conclusion.Confinement increased the risk of tobacco and cannabis use. Motives for use also increased, except those associated with alcohol use in university students. Problem tobacco use was motivated by social and coping needs; alcohol and cannabis use was motivated by social, entertainment, coping and expansion needs

Patrones de victimización por violencia en el noviazgo y consumo de alcohol en adolescentes estudiantes del sur de Jalisco, México / Patterns of dating violence victimization and alcohol consumption among adolescent students from southern Jalisco, Mexico

Resumen Estudios sugieren la presencia de patrones de violencia en las relaciones de noviazgo durante la adolescencia. En la población adolescente mexicana se conoce poco sobre los patrones de abuso cara a cara y digital en el noviazgo y cómo pueden ser explicados por el consumo de alcohol. El objetivo de esta investigación fue identificar los patrones de victimización por abuso en las relaciones de noviazgo y determinar si el consumo de alcohol predice los patrones encontrados. Fue un estudio transversal con alcance explicativo. Participaron 398 adolescentes estudiantes (62.8% mujeres) de 15 a 18 años de edad (M = 16.1 años; DT = 1). Se usó un análisis de clases latentes y se encontraron tres clases: 1) violencia generalizada baja (45%), 2) violencia psicológica moderada y control digital alto (38%) y 3) violencia generalizada alta (17%). Se encontró que el consumo de alcohol se asoció con la pertenencia a la clase de violencia psicológica moderada y control digital alto (β = 0.48, p = .022) y con la pertenencia a la clase de violencia generalizada alta (β = 0.66, p = .004). Es importante considerar, en la generación de intervenciones, la existencia de patrones de violencia en el noviazgo en adolescentes y la influencia que tiene el consumo de alcohol sobre estos.

Abstract Studies suggest the existence of patterns of dating violence during adolescence. In the adolescent Mexican population, little is known about the patterns of face-to-face and cyber dating abuse and to what extent they can be explained by alcohol consumption. The aim of this research was to identify patterns of dating abuse victimization and to determine whether alcohol use predicts the patterns found. It was a cross-sectional study with an explanatory scope. A total of 398 adolescent students (62.8% women) from 15 to 18 years of age (M = 16.1 years; SD = 1) participated in the study. Latent class analysis was used, and three classes were found: 1) low generalized violence (45%); 2) moderate psychological violence and high digital control (38%); and 3) high generalized violence (17%). Alcohol consumption was found to be associated with the membership in the moderate psychological violence and high digital control (β = 0.48, p = .022) and were included in the high generalized violence class (β = 0.66, p = .004). It is important to consider, in the generation of interventions, the existence of patterns of violence in dating relationships among adolescents and the influence that alcohol consumption has on them.

Uso de substâncias psicoativas por universitários da área da saúde antes e durante a pandemia da covid-19: prevalência e fatores associados / Use of psychoactive substances by college students in the health sector before and during the COVID-19 pandemic: prevalence and associated factors / Uso de sustancias psicoactivas por los universitarios del área de la salud antes y durante la pandemia del COVID-19: prevalencia y factores asociados

A pandemia do coronavírus criou incertezas sobre os impactos da doença na saúde dos universitários relacionados ao padrão de uso de substâncias psicoativas. O objetivo deste estudo foi estimar a prevalência e os fatores associados ao uso de álcool, tabaco e drogas ilícitas entre universitários da área da saúde antes e durante a pandemia da covid-19. Trata-se de um estudo transversal com inquéritos repetidos. Para determinar o padrão de uso das substâncias psicoativas, utilizou-se o Teste de Triagem do Envolvimento com Álcool, Tabaco e Outras Substâncias (ASSIST). Foi realizada a análise de regressão logística com a medida do desfecho expressa por odds ratio e intervalo de confiança de 95%. Obtiveram-se as seguintes associações para o maior consumo de substâncias psicoativas antes da pandemia: homossexuais/bissexuais e tabaco no mês; não iniciantes no curso e álcool (na vida e no mês) e drogas ilícitas na vida. Ademais, a análise ajustada dos estudantes durante a pandemia demonstrou que a associação foi mantida: homossexuais/bissexuais e tabaco na vida e no mês, álcool no mês e drogas ilícitas na vida. Concluiu-se que a universidade deve buscar a implementação de políticas de assistência estudantil, garantindo aos alunos um bem-estar físico e emocional.

The coronavirus pandemic created uncertainty about the health impacts of the disease on college students related to the pattern of psychoactive substance use. The aim of this study was to estimate the prevalence and factors associated with alcohol, tobacco, and illicit drug use among university health students before and during the COVID-19 pandemic. This is a cross-sectional study, with repeated surveys. To determine the pattern of psychoactive substance use the Alcohol, Smoking and Substance Involvement Screening Test ­ (ASSIST) was used. The logistic regression analysis was performed with the measurement of the outcome expressed by odds ratio and 95% confidence interval. The following associations were obtained for the highest consumption of psychoactive substance before the pandemic: homosexuals/bisexuals and tobacco in the month; non-beginners in the course and alcohol (in life and in the month), and illicit drugs in life. Furthermore, the adjusted analysis of students during the pandemic showed that the association remained: homosexuals/bisexuals and tobacco in life and month, alcohol in month, and illicit drugs in life. In conclusion, the university must seek to implement student assistance policies, guaranteeing students' physical and emotional wellbeing.

La pandemia de coronavirus produjo incertidumbres sobre las repercusiones de la enfermedad en la salud de los estudiantes universitarios relacionadas con el patrón de consumo de sustancias psicoactivas. El objetivo de este estudio es estimar la prevalencia y los factores asociados al consumo de alcohol, tabaco y drogas ilícitas entre los estudiantes universitarios del área de la salud antes y durante la pandemia de COVID-19. Se trata de un estudio transversal, con encuestas repetidas. Para determinar el patrón de consumo de sustancias psicoactivas, se utilizó la Prueba de Detección de Consumo de Alcohol, Tabaco y Sustancias ­ASSIST. Se realizó un análisis de regresión logística con la medida de resultado expresada por odds ratio y un intervalo de confianza del 95%. Se obtuvieron las siguientes asociaciones para el mayor consumo antes de la pandemia: homosexuales/bisexuales y tabaco en el mes; no iniciados en el curso y alcohol (en la vida y en el mes) y drogas ilícitas en la vida. Además, el análisis ajustado de los estudiantes en la pandemia se mantuvo asociado con: homosexuales/bisexuales y tabaco en la vida y el mes, alcohol en el mes y drogas ilícitas en la vida. Se concluye que la universidad debe implementar políticas de asistencia a los estudiantes para garantizarles bienestar físico y emocional.