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1.
J Neuroeng Rehabil ; 21(1): 105, 2024 Jun 21.
Artigo em Inglês | MEDLINE | ID: mdl-38907255

RESUMO

BACKGROUND: The ankle is usually highly effective in modulating the swing foot's trajectory to ensure safe ground clearance but there are few reports of ankle kinetics and mechanical energy exchange during the gait cycle swing phase. Previous work has investigated ankle swing mechanics during normal walking but with developments in devices providing dorsiflexion assistance, it is now essential to understand the minimal kinetic requirements for increasing ankle dorsiflexion, particularly for devices employing energy harvesting or utilizing lighter and lower power energy sources or actuators. METHODS: Using a real-time treadmill-walking biofeedback technique, swing phase ankle dorsiflexion was experimentally controlled to increase foot-ground clearance by 4 cm achieved via increased ankle dorsiflexion. Swing phase ankle moments and dorsiflexor muscle forces were estimated using AnyBody modeling system. It was hypothesized that increasing foot-ground clearance by 4 cm, employing only the ankle joint, would require significantly higher dorsiflexion moments and muscle forces than a normal walking control condition. RESULTS: Results did not confirm significantly increased ankle moments with augmented dorsiflexion, with 0.02 N.m/kg at toe-off reducing to zero by the end of swing. Tibialis Anterior muscle force incremented significantly from 2 to 4 N/kg after toe-off, due to coactivation with the Soleus. To ensure an additional 4 cm mid swing foot-ground clearance, an estimated additional 0.003 Joules/kg is required to be released immediately after toe-off. CONCLUSION: This study highlights the interplay between ankle moments, muscle forces, and energy demands during swing phase ankle dorsiflexion, offering insights for the design of ankle assistive technologies. External devices do not need to deliver significantly greater ankle moments to increase ankle dorsiflexion but, they should offer higher mechanical power to provide rapid bursts of energy to facilitate quick dorsiflexion transitions before reaching Minimum Foot Clearance event. Additionally, for ankle-related bio-inspired devices incorporating artificial muscles or humanoid robots that aim to replicate natural ankle biomechanics, the inclusion of supplementary Tibialis Anterior forces is crucial due to Tibialis Anterior and Soleus co-activation. These design strategies ensures that ankle assistive technologies are both effective and aligned with the biomechanical realities of human movement.


Assuntos
Articulação do Tornozelo , Tornozelo , Músculo Esquelético , Tecnologia Assistiva , Humanos , Fenômenos Biomecânicos , Masculino , Adulto , Feminino , Articulação do Tornozelo/fisiologia , Tornozelo/fisiologia , Músculo Esquelético/fisiologia , Caminhada/fisiologia , Marcha/fisiologia , Adulto Jovem , Pé/fisiologia , Desenho de Equipamento , Biorretroalimentação Psicológica/instrumentação , Biorretroalimentação Psicológica/métodos , Cinética
2.
J Funct Morphol Kinesiol ; 9(2)2024 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-38651426

RESUMO

The aim of this study was to analyze lower leg muscle forces during strength exercises such as back squats, good mornings and split squats, with a particular emphasis on females. By focusing on females, who are more vulnerable to anterior cruciate ligament injuries, we aimed to better understand muscle engagement and its role in injury prevention. Eight participants were monitored during exercises with a barbell load of 25% of body weight and, during the back squat, an additional 50% load. The analysis was conducted using personalized musculoskeletal models, electromyography (EMG) and Vicon motion capture systems to assess various muscle groups, including the m. gluteus maximus and m. gluteus medius, as well as the hamstring and quadriceps muscles. The back squat produced the highest forces for the quadriceps muscles, particularly the rectus femoris (>25 N/kg), as well as in the back leg during the split squat (>15 N/kg). The gluteal muscles were most active during good mornings and in the front leg of the split squat, especially the m. gluteus maximus medial part (>20 N/kg). The hamstrings generated the highest muscle forces in the front leg of the split squat, with the greatest forces observed in the m. semimembranosus. Our research highlights how musculoskeletal modeling helps us to understand the relationship among muscles, joint angles and anterior cruciate ligament injury risks, especially in strength training females. The results emphasize the need for personalized exercise guidance and customized models to make strength training safer and more effective.

3.
J Biomech ; 166: 112055, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38522362

RESUMO

Glenohumeral biomechanics after rotator cuff (RC) tears have not been fully elucidated. This study aimed to investigate the muscle compensatory mechanism in weight-bearing shoulders with RC tears and asses the induced pathomechanics (i.e., glenohumeral translation, joint instability, center of force (CoF), joint reaction force). An experimental, glenohumeral simulator with muscle-mimicking cable system was used to simulate 30° scaption motion. Eight fresh-frozen shoulders were prepared and mounted in the simulator. Specimen-specific scapular anthropometry was used to test six RC tear types, with intact RC serving as the control, and three weight-bearing loads, with the non-weight-bearing condition serving as the control. Glenohumeral translation was calculated using instantaneous helical axis. CoF, muscle forces, and joint reaction forces were measured using force sensors integrated into the simulator. Linear mixed effects models (RC tear type and weight-bearing) with random effects (specimen and sex) were used to assess differences in glenohumeral biomechanics. RC tears did not change the glenohumeral translation (p > 0.05) but shifted the CoF superiorly (p ≤ 0.005). Glenohumeral translation and joint reaction forces increased with increasing weight bearing (p < 0.001). RC and deltoid muscle forces increased with the presence of RC tears (p ≤ 0.046) and increased weight bearing (p ≤ 0.042). The synergistic muscles compensated for the torn RC tendons, and the glenohumeral translation remained comparable to that for the intact RC tendons. However, in RC tears, the more superior CoF was close to where glenoid erosion occurs in RC tear patients with secondary osteoarthritis. These findings underscore the importance of early detection and precise management of RC tears.


Assuntos
Lesões do Manguito Rotador , Articulação do Ombro , Humanos , Ombro/fisiologia , Manguito Rotador/fisiologia , Articulação do Ombro/fisiologia , Fenômenos Biomecânicos , Suporte de Carga , Cadáver , Amplitude de Movimento Articular/fisiologia
4.
Sensors (Basel) ; 24(3)2024 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-38339749

RESUMO

Estimation of vivo muscle forces during human motion is important for understanding human motion control mechanisms and joint mechanics. This paper combined the advantages of the convolutional neural network (CNN) and long-short-term memory (LSTM) and proposed a novel muscle force estimation method based on CNN-LSTM. A wearable sensor system was also developed to collect the angles and angular velocities of the hip, knee, and ankle joints in the sagittal plane during walking, and the collected kinematic data were used as the input for the neural network model. In this paper, the muscle forces calculated using OpenSim based on the Static Optimization (SO) method were used as the standard value to train the neural network model. Four lower limb muscles of the left leg, including gluteus maximus (GM), rectus femoris (RF), gastrocnemius (GAST), and soleus (SOL), were selected as the studying objects in this paper. The experiment results showed that compared to the standard CNN and the standard LSTM, the CNN-LSTM performed better in muscle forces estimation under slow (1.2 m/s), medium (1.5 m/s), and fast walking speeds (1.8 m/s). The average correlation coefficients between true and estimated values of four muscle forces under slow, medium, and fast walking speeds were 0.9801, 0.9829, and 0.9809, respectively. The average correlation coefficients had smaller fluctuations under different walking speeds, which indicated that the model had good robustness. The external testing experiment showed that the CNN-LSTM also had good generalization. The model performed well when the estimated object was not included in the training sample. This article proposed a convenient method for estimating muscle forces, which could provide theoretical assistance for the quantitative analysis of human motion and muscle injury. The method has established the relationship between joint kinematic signals and muscle forces during walking based on a neural network model; compared to the SO method to calculate muscle forces in OpenSim, it is more convenient and efficient in clinical analysis or engineering applications.


Assuntos
Extremidade Inferior , Dispositivos Eletrônicos Vestíveis , Humanos , Músculo Esquelético/fisiologia , Redes Neurais de Computação , Caminhada/fisiologia
5.
J Biomech ; 162: 111867, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37992597

RESUMO

Recent developments in musculoskeletal (MS) modeling have been geared towards model customization. Personalization of the spine profile could affect estimates of spinal loading and stability, particularly in the upright standing posture where large inter-subject variations in the lumbar lordosis have been reported. This study investigates the biomechanical consequences of changes in the spinal profile. In 31 participants (healthy and with back pain), (1) the spine external profile was measured, (2) submaximal contractions were recorded in a dynamometer to calibrate the EMG-driven MS model and finally (3) static lifting in the upright standing challenging spine stability while altering load position and magnitude were considered. EMG signals of 12 trunk muscles and angular kinematics of 17 segments were recorded. For each participant, the MS model was constructed using either a generic or a personalized spinal profile and 17 biomechanical outcomes were computed, including individual muscle forces, ratios of muscle group forces, spinal loading and stability parameters. According to the ANOVA results and corresponding effect sizes, personalizing the spine profile induced medium and large effects on about half MS model outcomes related to the trunk muscle forces and negligible to small effects on spinal loading and stability as more aggregate outcomes. These effects are explained by personalized spine profiles that were a little more in extension as well as more pronounced spine curvatures (lordosis and kyphosis). These findings suggest that spine profile personalization should be considered in MS spine modeling as it may impact muscle force prediction and spinal loading.


Assuntos
Lordose , Humanos , Eletromiografia , Postura/fisiologia , Coluna Vertebral/fisiologia , Tronco/fisiologia , Músculo Esquelético/fisiologia , Fenômenos Biomecânicos , Suporte de Carga/fisiologia , Vértebras Lombares/fisiologia
6.
J Thorac Cardiovasc Surg ; 167(4): e78-e89, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37160219

RESUMO

OBJECTIVE: Estimating neochord lengths during mitral valve repair is challenging, because approximation must be performed largely based on intuition and surgical experience. Little data exist on quantifying the effects of neochord length misestimation. We aimed to evaluate the impact of neochord length on papillary muscle forces and mitral valve hemodynamics, which is especially pertinent because increased forces have been linked to aberrant mitral valve biomechanics. METHODS: Porcine mitral valves (n = 8) were mounted in an ex vivo heart simulator, and papillary muscles were fixed to high-resolution strain gauges while hemodynamic data were recorded. We used an adjustable system to modulate neochord lengths. Optimal length was qualitatively verified by a single experienced operator, and neochordae were randomly lengthened or shortened in 1-mm increments up to ±5 mm from the optimal length. RESULTS: Optimal length neochordae resulted in the lowest peak composite papillary muscle forces (6.94 ± 0.29 N), significantly different from all lengths greater than ±1 mm. Both longer and shorter neochordae increased forces linearly according to difference from optimal length. Both peak papillary muscle forces and mitral regurgitation scaled more aggressively for longer versus shorter neochordae by factors of 1.6 and 6.9, respectively. CONCLUSIONS: Leveraging precision ex vivo heart simulation, we found that millimeter-level neochord length differences can result in significant differences in papillary muscle forces and mitral regurgitation, thereby altering valvular biomechanics. Differences in lengthened versus shortened neochordae scaling of forces and mitral regurgitation may indicate different levels of biomechanical tolerance toward longer and shorter neochordae. Our findings highlight the need for more thorough biomechanical understanding of neochordal mitral valve repair.


Assuntos
Implante de Prótese de Valva Cardíaca , Insuficiência da Valva Mitral , Animais , Suínos , Músculos Papilares/cirurgia , Insuficiência da Valva Mitral/cirurgia , Fenômenos Biomecânicos , Cordas Tendinosas/cirurgia , Implante de Prótese de Valva Cardíaca/métodos
7.
J Biomech ; 159: 111794, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37690366

RESUMO

The study aims to investigate the effects of different loads and speed during running on inter- and intra-individual muscle force amplitudes, variabilities and coordination patterns. Nine healthy participants ran on an instrumentalized treadmill with an empty weight vest at two velocities (2.6 m/s and 3.3 m/s) or while carrying three different loads (4.5, 9.1, 13.6 kg) at 2.6 m/s while kinematics and kinetics were synchronously recorded. The major lower limb muscle forces were estimated using a musculoskeletal model. Muscle force amplitudes and variability, as well as coordination patterns were compared at the group and at the individual level using respectively statistical parametric mapping and covariance matrices combined with multidimensional scaling. Increasing the speed or the load during running increased most of the muscle force amplitudes (p < 0.01). During the propulsion phase, increasing the load increased muscle force variabilities around the ankle joint (modification of standard deviation up to 5% of body weight (BW), p < 0.05) while increasing the speed decreased variability for almost all the muscle forces (up to 10% of BW, p < 0.05). Each runner has a specific muscle force coordination pattern signature regardless of the different experimental conditions (p < 0.05). Yet, this individual pattern was slightly adapted in response to a change of speed or load (p < 0.05). Our results suggest that adding load increases the amplitude and variability of muscle force, but an increase in running speed decreases the variability. These findings may help improve the design of military or trail running training programs and injury rehabilitation by progressively increasing the mechanical load on anatomical structures.


Assuntos
Músculos , Corrida , Humanos , Extremidade Inferior/fisiologia , Articulação do Tornozelo/fisiologia , Corrida/fisiologia , Fenômenos Biomecânicos
8.
Bioengineering (Basel) ; 10(9)2023 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-37760108

RESUMO

In vitro biomechanical experiments utilizing cadaveric specimens are one of the most effective methods for rehearsing surgical procedures, testing implants, and guiding postoperative rehabilitation. Applying dynamic physiological muscle force to the specimens is a challenge to reconstructing the environment of bionic mechanics in vivo, which is often ignored in the in vitro experiment. The current work aims to establish a hardware platform and numerical computation methods to reproduce dynamic muscle forces that can be applied to mechanical testing on in vitro specimens. Dynamic muscle loading is simulated through numerical computation, and the inputs of the platform will be derived. Then, the accuracy and robustness of the platform will be evaluated through actual muscle loading tests in vitro. The tests were run on three muscles (gastrocnemius lateralis, the rectus femoris, and the semitendinosus) around the knee joint and the results showed that the platform can accurately reproduce the magnitude of muscle strength (errors range from -6.2% to 1.81%) and changing pattern (goodness-of-fit range coefficient ranges from 0.00 to 0.06) of target muscle forces. The robustness of the platform is mainly manifested in that the platform can still accurately reproduce muscle force after changing the hardware combination. Additionally, the standard deviation of repeated test results is very small (standard ranges of hardware combination 1: 0.34 N~2.79 N vs. hardware combination 2: 0.68 N~2.93 N). Thus, the platform can stably and accurately reproduce muscle forces in vitro, and it has great potential to be applied in the future musculoskeletal loading system.

9.
J Neuroeng Rehabil ; 20(1): 130, 2023 09 26.
Artigo em Inglês | MEDLINE | ID: mdl-37752507

RESUMO

Different research fields, such as biomechanics, medical engineering or neurosciences take part in the development of biomechanical models allowing for the estimation of individual muscle forces involved in motor action. The heterogeneity of the terminology used to describe these models according to the research field is a source of confusion and can hamper collaboration between the different fields. This paper proposes a common language based on lexical disambiguation and a synthesis of the terms used in the literature in order to facilitate the understanding of the different elements of biomechanical modeling for force estimation, without questioning the relevance of the terms used in each field or the different model components or their interest. We suggest that the description should start with an indication of whether the muscle force estimation problem is solved following the physiological movement control (from the nervous drive to the muscle force production) or in the opposite direction. Next, the suitability of the model for force production estimation at a given time or for monitoring over time should be specified. Authors should pay particular attention to the method description used to find solutions, specifying whether this is done during or after data collection, with possible method adaptations during processing. Finally, the presence of additional data must be specified by indicating whether they are used to drive, assist, or calibrate the model. Describing and classifying models in this way will facilitate the use and application in all fields where the estimation of muscle forces is of real, direct, and concrete interest.


Assuntos
Engenharia , Músculos , Humanos , Fenômenos Biomecânicos , Idioma
10.
Comput Biol Med ; 165: 107376, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37611422

RESUMO

Accurate predictions of spinal loads in subject-specific musculoskeletal models require precise body segment parameters, including segment mass and center of mass (CoM) locations. Existing upper body models often assume a constant percentage of total body mass to calculate segmental masses, disregarding inter-individual variability and limiting their predictive capacity. This study evaluated the sensitivity of subject-specific upper body musculoskeletal model predictions to body mass scaling methods. The upper body segmental masses and corresponding CoM of six male subjects with varying body mass indices were computed using two mass scaling methods: the constant-percentage-based (CPB) scaling method, commonly used in AnyBody software; and our recently developed body-shape-based (BSB) method. Subsequently, these values were used by a validated musculoskeletal model to predict the muscle and disc forces in upright and flexed postures. The discrepancies between the results of the two scaling methods were compared across subjects and postures. Maximum deviations in thorax masses reached up to 7.5% of total body weight (TBW) in overweight subjects, while maximum CoM location differences of up to 35 mm were observed in normal weight subjects. The root mean squared errors (RMSE) of the CPB results, calculated with the BSB results as baseline, showed that the muscle and shear forces of the two scaling methods were quite similar (<4.5% of TBW). Though, there were small to moderate differences in compressive forces (6.5-16.0% of TBW). Thus, the compressive forces predicted with CPB method should be used with caution, particularly for overweight and obese subjects.


Assuntos
Sobrepeso , Coluna Vertebral , Humanos , Masculino , Suporte de Carga/fisiologia , Fenômenos Biomecânicos , Postura/fisiologia , Músculo Esquelético/fisiologia
11.
Comput Biol Med ; 164: 107292, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37544250

RESUMO

BACKGROUND: Distal radius fractures (DRFs) treated with volar locking plates (VLPs) allows early rehabilitation exercises favourable to fracture recovery. However, the role of rehabilitation exercises induced muscle forces on the biomechanical microenvironment at the fracture site remains to be fully explored. The purpose of this study is to investigate the effects of muscle forces on DRF healing by developing a depth camera-based fracture healing model. METHOD: First, the rehabilitation-related hand motions were captured by a depth camera system. A macro-musculoskeletal model is then developed to analyse the data captured by the system for estimating hand muscle and joint reaction forces which are used as inputs for our previously developed DRF model to predict the tissue differentiation patterns at the fracture site. Finally, the effect of different wrist motions (e.g., from 60° of extension to 60° of flexion) on the DRF healing outcomes will be studied. RESULTS: Muscle and joint reaction forces in hands which are highly dependent on hand motions could significantly affect DRF healing through imposed compressive and bending forces at the fracture site. There is an optimal range of wrist motion (i.e., between 40° of extension and 40° of flexion) which could promote mechanical stimuli governed healing while mitigating the risk of bony non-union due to excessive movement at the fracture site. CONCLUSION: The developed depth camera-based fracture healing model can accurately predict the influence of muscle loading induced by rehabilitation exercises in distal radius fracture healing outcomes. The outcomes from this study could potentially assist osteopathic surgeons in designing effective post-operative rehabilitation strategies for DRF patients.


Assuntos
Fraturas do Rádio , Fraturas do Punho , Humanos , Fraturas do Rádio/cirurgia , Fixação Interna de Fraturas , Articulação do Punho , Músculo Esquelético , Placas Ósseas , Amplitude de Movimento Articular , Resultado do Tratamento
12.
Int J Numer Method Biomed Eng ; 39(4): e3680, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36606738

RESUMO

Heavy deadlift is used as a physical fitness screening tool in the U.S. Army. Despite the relevance of such a screening tool to military tasks performed by Service Members, the biomechanical impact of heavy deadlift and its risk of low-back injury remain unknown. A kinematics-driven musculoskeletal model of spine was implemented to investigate biomechanics of the lower back in a volunteer (23 years old, height of 1.82 m, and body mass of 98.8 kg) during a 68 kg deadlift. In search of protective mechanisms, effects of model personalization and variations in trunk musculature and lumbopelvic rhythm were also investigated. The net moment, compression and shear forces at the L5-S1 reached peaks of 684 Nm, 17.2 and 4.2 kN, respectively. Geometrical personalization and changes in lumbopelvic rhythm had the least effects on predictions while increases in muscle moment arms (40%) had the largest effects that caused, respectively, 32% and 36% decrease in the maximum compressive and shearing forces. Initiating wrapping of back muscles at farther distances from the spine had opposing effects on spinal loads; peak compression at the L5-S1 decreased by 12% whereas shear increased by 19%. Despite mechanisms considered, spinal loads during heavy deadlift exceed the existing evidence concerning the threshold of injury for spinal segments, suggesting the vulnerability to injury. Chronic exposure to such high-spinal loads may lead to (micro) fractures, degeneration, pathoanatomical changes and finally low-back pain.


Assuntos
Postura , Coluna Vertebral , Humanos , Adulto Jovem , Adulto , Postura/fisiologia , Coluna Vertebral/fisiologia , Tronco/fisiologia , Músculo Esquelético/fisiologia , Fenômenos Biomecânicos/fisiologia , Suporte de Carga/fisiologia , Vértebras Lombares
13.
Comput Methods Programs Biomed ; 230: 107351, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36709556

RESUMO

The aim of this study was to investigate the influence of the muscle force contribution and loading cycle discretization on the predicted micromotion and interfacial bone strains in the implanted acetabulum. To this end, a patient specific finite element model of the hemipelvis was developed, based on the CT-scan and gait analysis results, collected as part of the authors' previous work. Outcomes of this study suggests that the acetabular cup micromotion and interfacial bone strains can be predicted just using the joint contact force. This helps to reduce the complexity of the finite element models by ignoring the contribution of muscle forces and the associated challenges of mapping these forces to the pelvis. However, the gait cycle needs to be adequately discretised to capture the micromotion at the bone-implant interface. BACKGROUND AND OBJECTIVE: The Dalstra load case, which includes muscle forces, has been widely adopted in the literature for studying the mechanical environment in the intact and implanted acetabulum. To simplify the modelling approach, some researchers ignore the contribution of muscle forces. The Dalstra load case is also divided into eight separate load steps (five in the stance phase and three in the swing phase), however, it is unclear whether this adequately captures the micromotions, for a cementless acetabular cup, during a simulated activity. The aim of this study was to investigate the influence of the muscle force contribution and loading cycle discretization on the predicted micromotion and interfacial bone strains. METHODS: In this work, a patient specific finite element model of the hemipelvis was developed, based on the CT-scan and gait analysis results, collected as part of the authors' previous work. Finite element simulations were performed using the joint contact and muscle forces derived from two sources. The first approach was used the load case proposed by Dalstra et al. The second approach used joint contact and muscle forces predicted by a musculoskeletal model. Additionally, the musculoskeletal load case was discretised into 50 equal load steps and the results compared with the equivalent Dalstra load steps. RESULTS: The results showed that the contribution of the muscle forces resulted in minor differences in both the magnitude and distribution of the predicted acetabular micromotion (up to 4.01% in the mean acetabular micromotion) and interfacial bone strains (up to 10.34% in the mean interfacial bone strains). The degree of gait cycle discretisation had a significant influence on the acetabular micromotion with a difference of 20.89% in the mean acetabular micromotion. CONCLUSION: Outcomes of this study suggests that the acetabular cup micromotion and interfacial bone strains can be predicted just using the joint contact force. This helps to reduce the complexity of the finite element models by ignoring the contribution of muscle forces and the associated challenges of mapping these forces to the pelvis. However, the gait cycle needs to be adequately discretised to capture the micromotion at the bone-implant interface.


Assuntos
Acetábulo , Prótese de Quadril , Humanos , Acetábulo/fisiologia , Análise de Elementos Finitos , Marcha/fisiologia , Músculos
14.
Sports Biomech ; 22(8): 1041-1062, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32623961

RESUMO

In order to address gaps in the literature, this study assessed the reproducibility (i.e., difference between and within sessions) of joint and muscle forces using wearable sensors during stationary cycling. Seventeen male cyclists performed two sessions on a cycle ergometer cycling at a combination of three power outputs (1.5, 2.5 and 3.5 W/kg) and three pedalling cadences (60, 80 and 100 rpm) in two sessions (2-7 days apart). The first trial from each session was repeated at the end of the session for assessment of within-session reproducibility. Three-dimensional (3D) full-body motion and 3D bilateral pedal forces were collected using an inertial motion tracking system and a pair of instrumented pedals, respectively. Joint angles, muscle forces and knee joint forces were computed using OpenSim. Poor to excellent agreement (ICCs = 0.31-0.99) was observed and differences were trivial to small and non-significant between trials within-session. Poor to excellent agreement (ICCs = 0.05-0.97) was observed and differences were trivial to large between sessions. Variability can be attributed to changes in muscle recruitment strategies (within and between-sessions) and to repositioning of sensors (between-sessions).


Assuntos
Articulação do Joelho , Dispositivos Eletrônicos Vestíveis , Humanos , Masculino , Reprodutibilidade dos Testes , Fenômenos Biomecânicos , Articulação do Joelho/fisiologia , , Ciclismo/fisiologia
15.
J Clin Med ; 11(24)2022 Dec 14.
Artigo em Inglês | MEDLINE | ID: mdl-36556031

RESUMO

There is increasing interest in reverse total shoulder arthroplasty (RTSA) as a reliable treatment for arthritic, rotator cuff deficient shoulders. Humeral and glenoid version are controversial parameters that can influence internal and external rotation, muscular forces, and implant stability as outcomes of RTSA. The aim of this study was to obtain an overview of the current knowledge on the effect of both humeral component version and glenoid component version and give recommendations on their most optimal degree for RTSA. A comprehensive quantitative review of the published literature on the effect of humeral version and glenoid version in RTSA was performed, to identify its influence on the range of movement, muscle forces, and intrinsic stability of the reverse prosthesis. Eleven studies were included: nine were biomechanical studies, one was a clinical-radiographic study, and one was an implant design consideration. Anterior stability can be improved by implanting the humeral component in neutral or with some anteversion. Glenoid component retroversion has been proven to reduce the likelihood of subluxation, while increasing ER and ROM at the same time. The study was conducted considering 5° anteversion; neutral; and 5°, 10°, and 20° retroversion of the glenoid component. Although a final opinion has not been yet expressed on the matter, the general consensus tends to agree on restoring 0° to 20° of retroversion of the humeral and glenoid component to yield the best outcomes.

16.
Circ Cardiovasc Interv ; 15(12): e011928, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-36538583

RESUMO

BACKGROUND: Recent studies have linked mitral valve prolapse to localized myocardial fibrosis, ventricular arrhythmia, and even sudden cardiac death independent of mitral regurgitation or hemodynamic dysfunction. The primary mechanistic theory is rooted in increased papillary muscle traction and forces due to prolapse, yet no biomechanical evidence exists showing increased forces. Our objective was to evaluate the biomechanical relationship between prolapse and papillary muscle forces, leveraging advances in ex vivo modeling and technologies. We hypothesized that mitral valve prolapse with limited hemodynamic dysfunction leads to significantly higher papillary muscle forces, which could be a possible trigger for cellular and electrophysiological changes in the papillary muscles and adjacent myocardium. METHODS: We developed an ex vivo papillary muscle force transduction and novel neochord length adjustment system capable of modeling targeted prolapse. Using 3 unique ovine models of mitral valve prolapse (bileaflet or posterior leaflet prolapse), we directly measured hemodynamics and forces, comparing physiologic and prolapsing valves. RESULTS: We found that bileaflet prolapse significantly increases papillary muscle forces by 5% to 15% compared with an optimally coapting valve, which are correlated with statistically significant decreases in coaptation length. Moreover, we observed significant changes in the force profiles for prolapsing valves when compared with normal controls. CONCLUSIONS: We discovered that bileaflet prolapse with the absence of hemodynamic dysfunction results in significantly elevated forces and altered dynamics on the papillary muscles. Our work suggests that the sole reduction of mitral regurgitation without addressing reduced coaptation lengths and thus increased leaflet surface area exposed to ventricular pressure gradients (ie, billowing leaflets) is insufficient for an optimal repair.


Assuntos
Insuficiência da Valva Mitral , Prolapso da Valva Mitral , Humanos , Animais , Ovinos , Prolapso da Valva Mitral/diagnóstico por imagem , Insuficiência da Valva Mitral/etiologia , Músculos Papilares , Valva Mitral , Resultado do Tratamento , Prolapso , Fibrose
17.
Sensors (Basel) ; 22(18)2022 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-36146352

RESUMO

This two-experiment study aimed to examine the effects of different habitual foot placement angles and also the effects of manipulating the foot placement angle on the kinetics, three-dimensional kinematics and muscle forces of the squat. In experiment 1, seventy lifters completed squats at 70% of their one repetition maximum using a self-preferred placement angle. They were separated based on their habitual foot angle into three groups HIGH, MEDIUM and LOW. In experiment 2, twenty lifters performed squats using the same relative mass in four different foot placement angle conditions (0°, 21°, 42° and control). Three-dimensional kinematics were measured using an eight-camera motion analysis system, ground reaction forces (GRF) using a force platform, and muscle forces using musculoskeletal modelling techniques. In experiment 1, the impulse of the medial GRF, in the descent and ascent phases, was significantly greater in the HIGH group compared to LOW, and in experiment 2 statistically greater in the 42° compared to the 21°, 0° and control conditions. Experiment 2 showed that the control condition statistically increased quadriceps muscle forces in relation to 0°, whereas the 0° condition significantly enhanced gluteus maximus, gastrocnemius and soleus forces compared to control. In experiment 1, patellofemoral joint stress was significantly greater in the HIGH group compared to LOW, and in experiment 2, patellar and patellofemoral loading were statistically greater in the control compared to the 42°, 21°, 0° and control conditions. Owing to the greater medial GRF's, increased foot placement angles may improve physical preparedness for sprint performance and rapid changes of direction. Reducing the foot angle may attenuate the biomechanical mechanisms linked to the aetiology of knee pathologies and to promote gluteus maximus, gastrocnemius and soleus muscular development. As such, though there does not appear to be an optimal foot placement angle, the observations from this study can be utilised by both strength and conditioning and sports therapy practitioners seeking to maximise training and rehabilitative adaptations.


Assuntos
, Postura , Fenômenos Biomecânicos , Humanos , Articulação do Joelho/fisiologia , Extremidade Inferior , Masculino , Músculo Esquelético/fisiologia , Postura/fisiologia
18.
Int J Numer Method Biomed Eng ; 38(11): e3646, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-36054682

RESUMO

About a third of knee joint disorders originate from the patellofemoral (PF) site that makes stair ascent a difficult activity for patients. A detailed finite element model of the knee joint is coupled to a lower extremity musculoskeletal model to simulate the stance phase of stair ascent. It is driven by the mean of measurements on the hip-knee-ankle moments-angles as well as ground reaction forces reported in healthy individuals. Predicted muscle activities compare well to the recorded electromyography data. Peak forces in quadriceps (3.87 BW, body weight, at 20% instance in our 607 N subject), medial hamstrings (0.77 BW at 20%), and gastrocnemii (1.21 BW at 80%) are estimated. Due to much greater flexion angles-moments in the first half of stance, large PF contact forces (peak of 3.1 BW at 20% stance) and stresses (peak of 4.83 MPa at 20% stance) are estimated that exceed their peaks in level walking by fourfold and twofold, respectively. Compared with level walking, ACL forces diminish in the first half of stance but substantially increase later in the second half (peak of 0.76 BW at 75% stance). Under nearly similar contact forces at 20% of stance, the contact stress on the tibiofemoral (TF) medial plateau reaches a peak (9.68 MPa) twice that on the PF joint suggesting the vulnerability of both joints. Compared with walking, stair ascent increases peak ACL force and both peak TF and PF contact stresses. Reductions in the knee flexion moment and/or angle appear as a viable strategy to mitigate internal loads and pain.


Assuntos
Articulação do Joelho , Caminhada , Humanos , Fenômenos Biomecânicos , Articulação do Joelho/fisiologia , Caminhada/fisiologia , Músculo Esquelético/fisiologia , Ligamentos , Marcha/fisiologia
19.
Sports (Basel) ; 10(9)2022 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-36136391

RESUMO

This two-experiment study aimed to explore habitual and manipulated stance widths on squat biomechanics. In experiment one, 70 lifters completed back squats at 70%, 1 repetition maximum (1RM), and were split into groups (NARROW < 1.06 * greater trochanter width (GTW), MID 1.06−1.18 * GTW and WIDE > 1.37 * GTW) according to their self-selected stance width. In experiment two, 20 lifters performed squats at 70%, 1RM, in three conditions (NARROW, MID and WIDE, 1.0, 1.25 and 1.5 * GTW). The three-dimensional kinematics were measured using a motion capture system, ground reaction forces (GRF) using a force platform, and the muscle forces using musculoskeletal modelling. In experiment two, the peak power was significantly greater in the NARROW condition, whereas both experiments showed the medial GRF impulse was significantly greater in the WIDE stance. Experiment two showed the NARROW condition significantly increased the quadriceps forces, whereas both experiments showed that the WIDE stance width significantly enhanced the posterior-chain muscle forces. The NARROW condition may improve the high mechanical power movement performance and promote the quadriceps muscle development. Greater stance widths may improve sprint and rapid change-of-direction performance and promote posterior-chain muscle hypertrophy. Whilst it appears that there is not an optimal stance width, these observations can be utilized by strength and conditioning practitioners seeking to maximize training adaptations.

20.
J Biomech ; 141: 111214, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35843182

RESUMO

The aim of this study was to analyse the kinematics and kinetics of the lower extremities in the sagittal plane, when running under unstable surface conditions. It was hypothesized that 1) a greater effect of the unstable surface would occur in the gastrocnemius, soleus, and tibialis anterior muscles, contributing to plantar- and dorsi-flexion, compared to muscles involved in hip and knee movements, and 2) the step-to-step absolute variability would be larger in the unstable condition. Eleven male-subjects completed running trials on stable and unstable surfaces in a laboratory setup. Inverse kinematic and dynamic analyses were conducted to calculate kinematics and moments at the lower extremity joints. Additionally, muscle force and activation related variables were calculated for six lower limb muscles using musculoskeletal modelling. Furthermore, the individual SD was calculated for all the variables as a measurement of absolute step-to-step variability. The unstable surface led to a decrease in joint ROM of the knee and ankle by 8.3% and 11.4%, and a decrease of 13.3% on average in force development of the ankle plantar-flexor, which also was reflected by decreasing muscle peak forces of Soleus and Gastrocnemius of 10.3% and 10.8%. Furthermore, an increase of force of Biceps Femoris and activation of Vastus Lateralis were found during the unstable condition. The step-to-step variability increased up to 158% when changing to the unstable condition. In conclusion, the findings revealed for the first time, lower ankle muscle forces mostly reflecting biomechanical adjustments to the surface conditions as well as larger absolute variability when running on the unstable surface.


Assuntos
Corrida , Articulação do Tornozelo/fisiologia , Fenômenos Biomecânicos , Eletromiografia , Humanos , Articulação do Joelho/fisiologia , Extremidade Inferior/fisiologia , Masculino , Músculo Esquelético/fisiologia , Corrida/fisiologia
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