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1.
Sensors (Basel) ; 23(6)2023 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-36991735

RESUMO

We investigate the in-network processing of a skyline join query in wireless sensor networks (WSNs). While much research was conducted on processing skyline queries in WSNs, skyline join queries were dealt with only in traditional centralized or distributed database environments. However, such techniques cannot be applied to WSNs. Carrying out join filtering, as well as skyline filtering using them in WSNs, is infeasible due to limited memory in senor nodes and to excessive energy consumption in wireless communications. In this paper, we propose a protocol to process a skyline join query in WSNs energy efficiently with only a small amount of memory in each sensor node. It uses a synopsis of skyline attribute value ranges, which is a very compact data structure. The range synopsis is used both in the search of anchor points for skyline filtering and in 2-way semijoins for join filtering. We describe the structure of a range synopsis and present our protocol. To optimize our protocol, we solve some optimization problems. Through implementation and a set of detailed simulations, we show the effectiveness of our protocol. The range synopsis is confirmed to be compact enough for our protocol to work well with the limited memory and energy in each sensor node. For the correlated and random distributions, our protocol significantly outperforms other possible protocols, confirming the effectiveness of an in-network skyline as well as the join filtering capabilities of our protocol.

2.
Biosystems ; 224: 104836, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36640942

RESUMO

New tools and software in systems biology require testing and validation on reaction networks with desired characteristics such as number of reactions or oscillating behaviors. Often, there is only a modest number of published models that are suitable, so researchers must generate reaction networks with the desired characteristics, a process that can be computationally expensive. To reduce these computational costs, we developed a data base of synthetic reaction networks to facilitate reuse. The current database contains thousands of networks generated using directed evolution. The network are of two types: (1) those with oscillations in species concentrations and (2) those for which no oscillation was found using directed evolution. To facilitate access to networks of interest, the database is queryable by the number of species and reactants, the presence or absence of autocatalytic and degradation reactions, and the network behavior. Our analysis of the data revealed some interesting insights, such as the population of oscillating networks possess more autocatalytic reactions compared to random control networks. In the future, this database will be expanded to include other network behaviors.


Assuntos
Software , Biologia de Sistemas , Bases de Dados Factuais , Césio
3.
Artigo em Inglês | MEDLINE | ID: mdl-38567025

RESUMO

Given a road network and a set of trajectory data, the anomalous behavior detection (ABD) problem is to identify drivers that show significant directional deviations, hard-brakings, and accelerations in their trips. The ABD problem is important in many societal applications, including Mild Cognitive Impairment (MCI) detection and safe route recommendations for older drivers. The ABD problem is computationally challenging due to the large size of temporally-detailed trajectories dataset. In this paper, we propose an Edge-Attributed Matrix that can represent the key properties of temporally-detailed trajectory datasets and identify abnormal driving behaviors. Experiments using real-world datasets demonstrated that our approach identifies abnormal driving behaviors.

4.
Gene ; 535(2): 124-30, 2014 Feb 10.
Artigo em Inglês | MEDLINE | ID: mdl-24316489

RESUMO

Kashin-Beck disease (KBD) is a special type of endemic osteoarthritis. It has been suggested that alterations in selenium metabolism and apoptosis play a role in KBD. However, the underlying molecular mechanism remains largely unclear. We performed a microarray analysis using RNA isolated from cartilages of KBD patients and healthy controls, through Significance Analysis of Microarray (SAM) software. Functional gene networks and crucial molecules associated with differentially expressed genes were investigated via Ingenuity Pathway Analysis (IPA) and hub gene analysis. Quantitative real-time PCR was used to check the validation of chip test. We identified 52 up-regulated apoptosis-related genes and 26 down-regulated selenium-related genes between KBD and controls, and these genes associated with the "MYC-mediated apoptosis signaling pathway". We confirmed the results from array studies with quantitative real-time PCR analysis. Our results suggest that abnormal regulation of selenium metabolism and apoptosis through the MYC mediated signaling pathway contributes to the pathogenesis of KBD, but the relationship between apoptosis gene and selenium gene was not found.


Assuntos
Apoptose/genética , Cartilagem Articular/metabolismo , Regulação da Expressão Gênica , Doença de Kashin-Bek/genética , Osteoartrite/genética , Selênio/metabolismo , Transcriptoma , Adulto , Estudos de Casos e Controles , Feminino , Perfilação da Expressão Gênica , Redes Reguladoras de Genes , Humanos , Doença de Kashin-Bek/metabolismo , Masculino , Pessoa de Meia-Idade , Osteoartrite/metabolismo , Transdução de Sinais
5.
Sensors (Basel) ; 11(12): 11833-55, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22247695

RESUMO

Underwater sensor networks are emerging as a promising distributed data management system for various applications in underwater environments, despite their limited accessibility and restricted energy capacity. With the aid of recent developments in ubiquitous data computing, an increasing number of users are expected to overcome low accessibility by applying queries to underwater sensor networks. However, when multiple users send queries to an underwater sensor network in a disorganized manner, it may incur lethal energy waste and problematic network traffic. The current query management mechanisms cannot effectively deal with this matter due to their limited applicability and unrealistic assumptions. In this paper, a novel query management scheme involving query result merging is proposed for underwater sensor networks. The mechanism is based on a relational database model and is adjusted to the practical restrictions affecting underwater communication environments. Network simulations will prove that the scheme becomes more efficient with a greater number of queries and a smaller period range.


Assuntos
Água , Telemetria/métodos
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