Simplification of Deep Neural Network-Based Object Detector for Real-Time Edge Computing.

This paper presents a method for simplifying and quantizing a deep neural network (DNN)-based object detector to embed it into a real-time edge device. For network simplification, this paper compares five methods for applying channel pruning to a residual block because special care must be taken regarding the number of channels when summing two feature maps. Based on the comparison in terms of detection performance, parameter number, computational complexity, and processing time, this paper discovers the most satisfying method on the edge device. For network quantization, this paper compares post-training quantization (PTQ) and quantization-aware training (QAT) using two datasets with different detection difficulties. This comparison shows that both approaches are recommended in the case of the easy-to-detect dataset, but QAT is preferable in the case of the difficult-to-detect dataset. Through experiments, this paper shows that the proposed method can effectively embed the DNN-based object detector into an edge device equipped with Qualcomm's QCS605 System-on-Chip (SoC), while achieving a real-time operation with more than 10 frames per second.

Clustering analysis of tumor metabolic networks.

BACKGROUND: Biological networks are representative of the diverse molecular interactions that occur within cells. Some of the commonly studied biological networks are modeled through protein-protein interactions, gene regulatory, and metabolic pathways. Among these, metabolic networks are probably the most studied, as they directly influence all physiological processes. Exploration of biochemical pathways using multigraph representation is important in understanding complex regulatory mechanisms. Feature extraction and clustering of these networks enable grouping of samples obtained from different biological specimens. Clustering techniques separate networks depending on their mutual similarity. RESULTS: We present a clustering analysis on tissue-specific metabolic networks for single samples from three primary tumor sites: breast, lung, and kidney cancer. The metabolic networks were obtained by integrating genome scale metabolic models with gene expression data. We performed network simplification to reduce the computational time needed for the computation of network distances. We empirically proved that networks clustering can characterize groups of patients in multiple conditions. CONCLUSIONS: We provide a computational methodology to explore and characterize the metabolic landscape of tumors, thus providing a general methodology to integrate analytic metabolic models with gene expression data. This method represents a first attempt in clustering large scale metabolic networks. Moreover, this approach gives the possibility to get valuable information on what are the effects of different conditions on the overall metabolism.