A review of Patient Reported Outcome Measures (PROMs) for characterizing Long COVID (LC)-merits, gaps, and recommendations.

BACKGROUND: Individuals may experience a range of symptoms after the clearance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This condition is termed long COVID (LC) or Post-COVID-19 condition (PCC). Despite the appreciable number of symptoms documented to date, one key challenge remains in the robust characterization of LC outcomes. This review aimed to assess the properties, identify gaps, and provide recommendations for relevant descriptive and evaluative Patient-Reported Outcome Measurement (PROM) instruments that can be used to comprehensively characterize LC. METHODS: To achieve this objective, we identified and reviewed descriptive and evaluative PROM instruments that have been developed and validated to date with people living with LC. Our review assessed their properties, identified gaps, and recommended PROMs suitable for characterizing LC. To ensure a comprehensive and robust characterization of LC, we next identified, reviewed, and selected (with the input of patient partners) PROMs associated with the most frequently reported LC symptoms. The evaluation criteria included psychometric evidence, mode of delivery, cost, and administration time. RESULTS: Traditional matrix mapping revealed Post-COVID Functional Status Scale (PCFS) as a choice instrument for capturing LC outcomes largely because of the comprehensive domains it covered, and the number of psychometric evidence reported in literatures. This instrument can be effectively paired with the Fatigue Severity Scale (FSS), Montreal Cognitive Assessment (MoCA), Patient Health Questionnaire (PHQ-9), Headache Impact Test (HIT), Pittsburgh Sleep Quality Index (PSQI), and DePaul Symptom Questionnaire (DSQ-PEM) to characterize fatigue, cognitive impairment, depression/anxiety, headache, sleeplessness, and post-exertional malaise respectively. CONCLUSION: Our paper identified appropriate PROM instruments that can effectively capture the diverse impacts of LC. By utilizing these validated instruments, we can better understand and manage LC.

Some individuals who once contracted the virus responsible for COVID-19 may continue to experience a range of symptoms persisting for more than 3 months. These symptoms include fatigue, difficulty sleeping, anxiety and difficulty breathing amongst others. This condition is known by many as Long COVID (LC). To understand the health outcomes of patients faced with this condition, standardized Patient Reported Outcome Measurement instruments (PROMs) are pivotal. PROMs are standardized questionnaires completed by patients to measure their symptoms, perceptions of health status, and/or functional well-being. In this paper, we have examined standardized instruments suitable for measuring LC outcomes. We conducted a comprehensive strength and weakness analysis of each instrument reviewed, guided by specific criteria. Based on our strength and weakness analyses, we identified several potential instruments that can be used to reports patients' outcomes concerning LC. The data collected from PROMs provides valuable insights for healthcare practitioners and policy makers, enabling the enhancement of patient-centric care and serving as an instrument for systemic transformation.

Development and Validity Evidence of the Myths of Romantic Love Multidimensional Scale (MRL-MS) in Young Chileans

Romantic love myths refer to culturally shared beliefs about love, falling in love and relationships. Their study and evaluation are of utmost importance, given that they have been recognized as a risk factor in dating violence with serious implications for the well-being and mental health of young people. The aim of the present study was therefore to develop a scale to evaluate beliefs about romantic love, establishing evidence of reliability and validity for the interpretation of the scores obtained. An instrumental cross-sectional design was carried out, applying the Multidimensional Romantic Love Myths Scale (MRL-MS) to a sample of 1001 Chilean young people between 18 and 25 years of age. As a result, a scale composed of 40 items assessing 8 interrelated dimensions was obtained, with evidence of validity based on internal structure, adequate levels of reliability, and evidence of metric and scalar invariance between sexes. Finally, the limitations of the study are discussed and possible applications and guidelines for future research are proposed.

Los mitos del amor romántico refieren a creencias culturalmente compartidas sobre el amor, el enamoramiento y las relaciones de pareja. Su estudio y evaluación son de suma importancia, dado que se han reconocido como un factor de riesgo en la violencia en el noviazgo con graves implicancia en el bienestar y salud mental de los jóvenes. Por tanto, el objetivo del presente estudio es desarrollar una escala que permita evaluar las creencias sobre el amor romántico, estableciendo evidencias de fiabilidad y validez para la interpretación de las puntuaciones obtenidas. Se llevó a cabo un diseño transversal de tipo instrumental, aplicando la Escala Multidimensional Mitos del Amor Romántico (MRL-MS) a una muestra de 1001 jóvenes chilenos entre 18 y 25 años. Como resultado, se obtuvo una escala compuesta por 40 ítems que evalúan 8 dimensiones interrelacionadas, con evidencia de validez basada en la estructura interna, adecuados niveles de fiabilidad, y evidencias de invarianza métrica y escalar entre sexos. Finalmente, se discuten las limitaciones del estudio y se proponen posibles aplicaciones y directrices para futuras investigaciones.

The Development and Psychometric Evaluation of the HIV Stigmatizing Attitudes Scale (HSAS) in Tanzania.

HIV stigmatizing attitudes are embedded in social context, making it important to develop culturally specific tools for accurate measurement. The goal of this study was to develop and evaluate the psychometric properties of the HIV Stigmatizing Attitudes Scale (HSAS) in Moshi, Tanzania. Items were adapted based on a scale developed by Visser et al. which was one of the first to measure HIV stigmatizing attitudes in the general population (i.e., people not living with HIV). Items were translated into Swahili and modified with iterative feedback. The HSAS was administered to participants (N = 1494) in an HIV stigma reduction intervention study at two antenatal care clinics in Moshi, Tanzania. The HSAS was found to have strong domain coherence and high reliability based on Cronbach's alpha, Omega 6 coefficient values, and the composite reliability coefficient, and high validity based on content-oriented evidence, relations to other variables, and response process. Factor analysis revealed a two-factor structure (Moral Judgment and Interpersonal Distancing), consistent with the original Visser scale. The HSAS provides a robust way to measure HIV stigma in the Tanzanian context and can be culturally adapted to other settings.

A measure of functioning in adults With ADHD: Psychometric properties of the general life functioning scale-parent version.

OBJECTIVE: The General Life Functioning Scale (GLF) was developed to provide a complementary alternative to existing measures of impairment. We examined the psychometric properties of the GLF-Parent version (GLF-P), given the known value of informant ratings. METHODS: The GLF-P was administered to parents of adults with attention-deficit/hyperactivity disorder (ADHD) diagnosed in childhood and a nonADHD comparison group in the Pittsburgh ADHD Longitudinal Study. GLF-P ratings described 334 participants (ADHD = 186; comparison = 148) rated at age 25 (Mage = 24.80 years, SDage = 0.46, range = 24-26) and 401 participants (ADHD = 237; comparison = 164) rated at age 30 (Mage = 29.30, SDage = 0.64, range = 28-33). Exploratory (EFA) and confirmatory (CFA) factor analyses were used. RESULTS: EFAs suggested and CFAs confirmed a five-factor solution. We found measurement invariance across diagnostic and age groups, satisfactory internal consistency, construct validity, and known-group validity. CONCLUSION: Psychometric results suggest the GLF-P as a helpful adjunctive measure of functioning. Further research is needed to determine the utility of the GLF across diverse settings.

Medo de Ficar Solteiro: Evidências Psicométricas e de Validade de uma Medida / Miedo a Estar Sola: Evidencias Psicométricas y de Validez de una Medida / Psychometric and Validity Evidence of the Fear of Being Single Scale

Resumo O medo de ficar solteiro pode ocasionar alterações na qualidade de vida dos indivíduos, podendo afetar o bem-estar e a autoestima. Esta pesquisa teve por objetivo validar a Escala Medo de Ficar Solteiro (EMFS) para o Brasil, apresentando evidências de sua qualidade psicométrica por meio de dois estudos. Estudo 1 contou com 172 participantes (Idade M = 23,69, DP = 7,77; 64,5% mulheres) e reproduziu a estrutura unifatorial do modelo original, com seis itens. O Estudo 2 contou com 220 participantes (Idade M = 21,90, DP = 5,64; 59,5% mulheres) e confirmou a estrutura por meio de uma AFC, com índices satisfatórios (CFI = 0,96; TLI = 0,94), além de fornecer evidência quanto a invariância fatorial do instrumento em relação ao status de relacionamento dos participantes. Adicionalmente, apresentou-se validade convergente por meio de correlações significativas com solidão e escore de satisfação com a vida, além de ter sido observada diferença entre homens e mulheres quanto ao medo de ficar solteiro. Por fim, a medida apresentou índices adequados de confiabilidade (alfa de Cronbach, α = 0,88) e confiabilidade composta (CC = 0,82). Concluindo, a medida apresentou evidências satisfatórias para o seu uso no contexto brasileiro.

Resumen El miedo a estar soltero puede conducir a modificaciones en la calidad de vida de los individuos, que pueden afectar su bienestar y autoestima. Esta investigación tuvo como objetivo validar la Escala Miedo a Estar Soltero (EMES) en Brasil, presentando evidencias de su calidad psicométrica a través de dos estudios. Estudio 1 contó con 172 participantes (Edad M = 23.69, DE = 7,77; 64,5% mujeres) y se replica la estrutura unifactorial del instrumento, con seis ítems. Estudio contó con 220 participantes (Edad M = 21.90, DE = 5,6; 59,5% mujeres) y confirmó la estructura mediante una AFC, con índices satisfactorios (CFI = .96; TLI = .94), y proporcionó evidencia de la invariancia factorial del instrumento, en relación al estado de relacionamento dos Participantes. Además, sí presenta validez convergente a través de correlaciones significativas con la soledad y la pontuación de satisfacción con la vida, y se ha observado diferencia entre hombres y mujeres cuando el miedo a estar soltero. Por último, la medida mostró niveles adecuados de fiabilidad (alfa de Cronbach, α= 0,88) y fiabilidad compuesta (CC = 0,82). En conclusión, la medida presenta pruebas satisfactorias para su uso en el contexto brasileño.

Abstract The fear of being single can lead to changes in the quality of life of individuals, which may affect their well-being and self-esteem. This research aimed to validate the Fear of Being Single Scale (FBSS) for Brazil, presenting evidence of its psychometric quality through two studies. Study 1 had 172 participants (Age M = 23.69, SD = 7.77; 64.5% women) and replicated the one-factor structure of the instrument, with six items. Study 2 had 220 participants (Age M = 21.90, SD = 5.64; 59.5% women) and confirmed the structure using a CFA, with satisfactory indices (CFI = .96; TLI = .94), and provided evidence for the factorial invariance of the instrument, in relation to participants' relationship status. Additionally, convergent validity was presented through significant correlations with loneliness and life satisfaction scores, and a difference was also observed between men and women regarding the fear of being single. Finally, the scale showed adequate levels of reliability (Cronbach's alpha, α = 0.88) and composite reliability (CR = 0.82). In conclusion, the scale presented satisfactory evidence for its use in a Brazilian context.