An unusual presentation of calcifying odontogenic cyst with literature review.

The calcifying odontogenic cyst (COC) is an uncommon developmental odontogenic cyst, the oral counterpart of Malherbe's cutaneous calcifying epithelioma (pilomatricoma). This article presents two unique cases of calcifying odontogenic cysts each exhibiting distinctive histopathological features and its literature review. One case with an unexpected finding of cholesterol granuloma (CG), a rare occurrence in non-inflammatory cysts within an unusual location between two maxillary central incisors. One more instance involves the presence of a compound odontome in conjunction with COC. The cases underscore the clinical and histopathological diversity of COC and highlight the importance of radiological and histopathological assessments for accurate diagnosis. The unexpected association of COC with cholesterol granuloma challenges traditional diagnostic expectations. Additionally, the second case suggests that COCs may warrant sub-categorization to better understand their varied presentations and biological behavior. This article contributes to the expanding knowledge of COC, emphasizing the significance of documenting rare cases to enhance comprehension of its nature, pathogenesis, and oral cavity origin.

Rare Variant of a Giant Compound Odontoma of the Maxilla: A Case Report.

Benign odontogenic tumors that produce features resembling teeth are known as compound odontomas. This case report describes a unique case of a compound odontoma presenting in the patient's maxillary, the front region. This example highlights how crucial it is to diagnose and treat odontomas as soon as possible in order to avoid possible consequences like tooth displacement or failed eruption. It also emphasizes how important imaging methods are to accurately localizing and planning surgery for odontogenic tumors. The effective handling of this case offers important insights into the multidisciplinary approach needed for odontoma patient diagnosis, treatment, and follow-up.

Gigantic Multiple Odontomas of Jaws in a Pediatric Patient: A Rare Case.

Odontomas are mixed epithelial and mesenchymal tumor-like malformations (hamartoma) composed of dental hard and soft tissue, causing delayed teeth eruption. Multiple case reports have been published in the literature describing solitary, localized odontoma features in pediatric patients along with their treatment planning. This report presents clinical and radiographic features of gigantic multiple odontomas involving both jaws in a five-year-old boy.

The Enigma Unveiled: Expansile Compound-complex Odontoma in the Anterior Maxilla of a Teenager.

Aim and objective: The objective of this case report is to offer insight into an expansive compound-complex odontoma located in the anterior maxilla of a 15-year-old male. The focus is placed on the importance of early detection and the progressive comprehension of odontomas. Background: Odontomas are common odontogenic lesions that are frequently discovered during examinations for delayed tooth eruption. There are two distinct classifications for odontomas-compound odontomas and complex odontomas. With its own each set of characteristics. A timely diagnosis is critical for avoiding complications. Case description: A male individual aged 15 years exhibited an expansive compound-complex odontoma located in the anterior maxilla. The clinical examination showed delayed tooth eruption and asymptomatic swelling. The radiographic images showed a radiopaque mass with tooth-like structures and radiolucent borders affecting the surrounding dentition. A surgical excision procedure was conducted, followed by a subsequent histopathological examination confirming the diagnosis of compound-complex odontoma. The patient continued orthodontic treatment after a 1-year follow-up without recurrence. Clinical significance: This case emphasizes the importance of regular dental exams in detecting odontomas early. This observation also highlights the growing understanding of odontomas as hamartomatous odontogenic malformations and the challenges of diagnosing them clinically. Additional molecular investigations are required to facilitate the classification and elucidation of genetic factors. How to cite this article: Alhazmi YA. The Enigma Unveiled: Expansile Compound-complex Odontoma in the Anterior Maxilla of a Teenager. Int J Clin Pediatr Dent 2024;17(1):82-85.

Diminutive compound odontoma in a child: a case report with emphasis on early detection.

The odontoma is regarded as a hamartomatous process of the jaws. Most are discovered as an incidental radiographic finding, averaging 15 mm in size. This report describes a case of a diminutive odontoma that was surgically removed before the onset of eruptive and pathologic consequences. A compilation of documented complications and syndromes associated with odontomas is also presented.

Clinicoradiopathologic Analysis of Odontomas: A Retrospective Study of 242 Cases.

Odontomas are considered hamartomatous lesions and are one of the two most common odontogenic tumors of the jaw. Odontomas are classified as compound or complex. Recently, ameloblastic fibro-odontoma (AFO) and ameloblastic fibro-dentinoma were reclassified as developing odontomas. Though clinically odontomas are usually asymptomatic, they have adverse effects on adjacent teeth such as tooth impaction, delayed eruption, displacement of teeth, over-retention of teeth, and can give rise to odontogenic cysts within the jaw. We sought to evaluate the clinicoradiopathologic presentations of odontomas by collecting and analyzing the clinical, radiographic, and pathologic data of odontomas diagnosed in our institution from 2013 to 2022. Over this 10-year period, there were 242 patients with a histopathological and/or radiographic diagnosis of odontoma. There was no gender predilection and ages ranged from 3 to 101 years (median, 14 years). The second decade of life was the most prevalent (57.4%). There was no jaw predilection; however, the anterior jaw was the most common location. Ninety-four (38.8%) cases presented with clinical findings. The most common finding was tooth impaction (n = 83). Nine (3.7%) cases were histopathologically confirmed to be associated with other lesions such as dentigerous cysts (n = 8) and nasopalatine duct cyst (n = 1). The median age (25 years) of patients diagnosed with odontomas associated with cysts was older than patients with odontomas (14 years) without associated cysts. Compound odontomas were the most common type of odontoma compared to complex and AFOs with 71.4%, 26.6%, and 2%, respectively. The majority of compound odontomas involved the anterior jaw (69.3%) and mandible (54.9%) while the majority of complex odontomas involved the posterior jaw (59.6%) and maxilla (54.7%). The four AFOs were in the posterior jaw and 75% involved the maxilla. The median age (12 years) of patients diagnosed with AFO was the youngest compared to patients diagnosed with compound (13 years) and complex (16 years). In conclusion, we analyzed the clinical, radiographic, and pathologic features of 242 new cases of odontomas. Our study reaffirms that odontomas frequently affect the pediatric population and can disrupt their dentition. Based on the result of this study, our clinical recommendation to prevent problems to adjacent teeth from odontomas is for dentists to be apt in the diagnose of odontomas to ensure that they are surgically removed in a timely manner.

Compound Odontoma and Dentigerous Cyst Associated With an Unerupted Maxillary Canine Tooth in a Weimaraner Dog: A Case Report.

A 7-month-old, male, Weimaraner dog was presented for maxillary swelling. Clinical evaluation including radiographs and computed tomography revealed a large cystic lesion, unerupted right maxillary canine tooth, and mass presumed to be a compound odontoma. The cyst and mass were expansile and occupied a large portion of the nasal cavity displacing anatomical structures of the maxilla. The mass was excised via curettage through an intraoral surgical approach and the unerupted tooth and cystic lining were removed. Histopathology supported dentigerous cyst and compound odontoma. This case confirms the first report of concurrent development of dentigerous cyst and compound odontoma in a dog with successful treatment and 18-month follow-up with no recurrence.

Calcifying odontogenic cyst associated with compound odontoma - A rare entity.

Calcifying odontogenic cyst (COC) or Gorlin's cyst categorized as a distinct entity by Gorlin et al. in 1962. It is a rare benign developmental cystic lesion that accounts for less than 1% of all odontogenic cysts. It can occur in association with various types of odontogenic tumors such as odontomas. COC is a hybrid lesion of the jaw presenting a manifold variety of clinical behaviors and histopathological characteristics including cystic, solid (neoplastic), and aggressive forms. COC exhibits diversity in terms of its clinical presentations, histopathologic features, and biological behavior. Normally, it presents as asymptomatic, slow developing lesion affecting the maxilla and mandible equally with strong predilection for the anterior segment. Radiographically, these lesions usually present as a unilocular, well-defined radiolucency with radiopaque structures within the lesion, either as irregular calcifications or tooth-like densities. The distinct features of COC as solid or cystic lesions presents with an ameloblastomous component admixed with varying proportions of ghost cells and spherical calcifications. Here, we report an article of calcifying odontogenic cyst associated with compound odontoma in a young patient with lesion in the anterior mandible with review of the various terminologies and classification and histopathology.

Radiographic characteristics of odontomas in patients in the National Taiwan University Children's Hospital.

Background/purpose: Odontoma is the most common odontogenic tumor. A literature review revealed limited data for odontomas in Taiwan. This study evaluated the radiographic characteristics of odontomas in 1280 patients in the National Taiwan University Children's Hospital (NTUCH). Materials and methods: This retrospective study analyzed the odontomas based on examination of mainly panoramic radiographs and related radiographs of 1280 patients in the NTUCH. Chi-square test was used for trend analysis. Results: Among 1280 patients (710 boys and 570 girls), a total of 16 patients with odontomas (10 boys and 6 girls) were identified. There were 14 compound and 2 complex odontomas. The mean age of the patients was 10.38 years with the majority of odontomas occurring in the first (37.5%) and second decade (62.5%) of life. Odontomas had a marked predilection for the mandible (56.25%) and for the anterior region of the jaws (75%), particularly for the anterior maxilla (43.75%). Ten odontomas (62.5%) were associated with the impacted corresponding permanent teeth. The sagittal position of odontomas and vertical relation of odontomas to the corresponding permanent teeth were significantly correlated with the eruption rate of corresponding permanent teeth (P < 0.05). Conclusion: The odontomas occur most commonly in male patients with a male to female ratio of 1.67:1. The incidence of odontomas in our 1280 patients is 1.25%. The age range of patients with odontomas is 6-17 years. The most frequent location of odontomas is the anterior maxillary region. Odontoma is frequently associated with an impacted corresponding permanent tooth.

A spontaneous compound odontoma in an adult Sprague Dawley rat (Rattus norvegicus).

Reports of compound odontomas in rats are very rare. A 14-month-old adult male Sprague Dawley rat was found to have a hard mass associated with the caudal aspect of the left mandible. After 2 weeks of observation, the rat was euthanized due to the mass growing significantly in size and the rat losing >20% of its body weight. Grossly, the mass was well-circumscribed, 3.7 × 3 × 1.2 cm, hard and heterogeneously coloured white, tan and red. The mass was restricted to the mandibular bone and did not involve surrounding subcutaneous tissue. On cut surface, the mass was a similar colour and brittle. Histologically, there were numerous proto-teeth embedded in ossified stroma. Each proto-tooth had a central mesenchyme pulp surrounded by columnar odontoblasts and dentine matrix. The dentine was often bordered by enamel matrix, which was occasionally bounded by ameloblasts. These histological findings were consistent with a compound odontoma. This is the first report of a spontaneous compound odontoma in the caudal mandible of a rat.

Management of Mandibular Compound Odontoma With Numbness in the Lower Jaw.

Odontomas are considered to be among the more common odontogenic tumors in the oral cavity. Several authors classify them as hamartomas instead of actual tumors. Odontomes' precise etiology is still unknown. The majority of odontomas are found during routine radiography studies and are asymptomatic. Odontomes typically cause disruptions to the teeth's eruption, most frequently deflection or delayed eruption. Here, the reported study details the surgical management of a mandibular compound odontoma in a patient who presented with a complaint of numbness in his lower jaw.

Characteristics, Diagnosis and Treatment of Compound Odontoma Associated with Impacted Teeth.

Compound odontoma is a malformation typical of young adults below the age of 20, with a slight preference for the male gender and the anterior region of the maxilla. Clinically asymptomatic, it can be detected during a radiological investigation in connection with the persistence of deciduous dental elements and the impaction of definitive ones. The treatment of choice is excisional surgery and recurrence is a rare event. The need for orthodontic therapy for impacted elements is usually not necessary because in most cases, odontomas are small, circumscribed lesions the size of a permanent tooth. In this article, the diagnostic and therapeutic surgical excision procedure is presented in three patients at developmental age with large compound odontomas associated with at least one retained canine, and in two of the cases, with serious transmigration to the impacted tooth elements.

Odontoma mandibular inusual y su resolución: reporte de un caso / Unusual mandibular odontoma and its resolution: report of a case

Objetivo: El odontoma es una lesión hamartomatosa benigna formada por tejido dentario (cemento, esmalte, pul­ pa). Según su grado de diferenciación podrá ser clasificado en sus dos variantes: compuesto y complejo en una relación 2:1. El objetivo de este artículo es presentar un odontoma mixto de gran tamaño de localización mandibular y su resolución quirúrgica. Caso clínico: Se describe el caso de un paciente mascu­ lino de 16 años de edad, portador de ortodoncia, que presenta un odontoma mixto de gran tamaño de localización mandibular y su resolución quirúrgica utilizando planificación 3D y confección de placa de titanio customizada (AU)

Aim: Odontoma is a benign hamartomatous lesion formed by dental tissue (cementum, enamel, pulp). According to its degree of differentiation, it can be classified in its two variants: compound and complex in a 2:1 ratio. The objective of this article is to present a large mixed odontoma of mandi­ bular location and its surgical resolution. Clinical case: A 16-year-old male patient with ortho­ dontics, who presents a large mixed odontoma with mandibu­ lar location and its surgical resolution using 3D planning and customized titanium plate fabrication (AU)

A Rare Case of Peripheral Compound Odontoma and Review of the Literature.

Peripheral or extraosseous odontogenic tumors are rare oral soft tissue enlargements which demonstrate the same histologic features of their intraosseous counterparts but emerge in gingiva and mucosa. In this paper we report a case of peripheral odontoma in a 12-years-old female patient presented asymptomatic swelling in the palatal site. After the clinical and radiographic examination, excisional biopsy was applied to the lesion located entirely in the soft tissue of maxillary incisors. Histopathologically presence of tooth-like structures containing dentin with regular canals and partly enamel matrix were observed. Our aim is to present the extremely rare case of peripheral odontoma and to review the literature for demonstrating the frequency and clinicopathologic features of this entity.

Compound Odontoma of the Anterior Maxilla Associated with Displaced Lateral Incisor: A Case Report.

INTRODUCTION: Odontomas are the most common odontogenic tumors worldwide and are usually chance findings seen on routine dental examinations. However, on progression, they may be associated with adjacent tooth displacement. CASE DESCRIPTION: We report a case of an 11-year-old girl who presented at the Lagos University Teaching Hospital (LUTH) pediatric dental clinic with a complaint of painless enlargement of the left anterior maxilla of 2-years duration. The swelling was located between teeth 21 and 22 and was associated with distal displacement and mesial angulation of tooth 22. Clinical, radiographic and histopathologic investigations revealed a compound odontoma. Surgical exposure and enucleation was done to remove the tumor. The patient's postoperative course and 6 months follow-up were uneventful. CONCLUSION: This report elucidates the importance of routine dental check-ups and minimally traumatic management of odontomas in pediatric dental patients to prevent adverse effects of odontomas, thereby, minimizing the interventions needed after surgical enucleation.

INTRODUCTION: Les odontomes sont les tumeurs odontogènes les plus courantes dans le monde et sont habituellement des découvertes fortuites observées lors des examens dentaires de routine. Cependant, lors de leur progression, ils peuvent être associés à un déplacement des dents adjacentes. DESCRIPTION DU CAS: Nous rapportons le cas d'une jeune fille de 11 ans qui s'est présentée à la clinique dentaire pédiatrique du Lagos University Teaching Hospital (LUTH) pour se plaindre d'un élargissement indolore du maxillaire antérieur gauche depuis deux ans. Le gonflement était situé entre les dents 21 et 22 et était associé à un déplacement distal et à une angulation mésiale de la dent 22. Les examens cliniques, radiographiques et histopathologiques ont révélé un odontome composé. Une exposition chirurgicale et une énucléation ont été effectuées pour retirer la tumeur. L'évolution postopératoire du patient et son suivi à 6 mois se sont déroulés sans incident. CONCLUSION: Ce rapport met en évidence l'importance des contrôles dentaires de routine et de la prise en charge des odontomes par des moyens peu traumatisants chez les patients pédiatriques afin de prévenir les effets indésirables des odontomes et de minimiser ainsi les interventions nécessaires après l'énucléation chirurgicale. Mots clés: Odontome composé, maxillaire antérieur, incisive latérale déplacée.

Compound Odontoma Removed by Endoscopic Intraoral Approach: Case Report.

A 12-year-old Japanese boy was referred to our hospital for evaluation of a radiopaque area on the left side of the mandible. Radiographic and computed tomographic examinations revealed a radiopaque lesion located on the lingual side, along with permanent tooth eruption. Several small tooth-like structures were noted within the lesion and the mandibular left second premolar was inclined in a mesial direction. An odontoma was clinically diagnosed and surgical removal by an endoscopic intraoral approach under general anesthesia was planned. Reports of oral surgery using an endoscopic approach have been presented, though none for an odontoma. With the expectation that removal of the odontoma would improve dentition in this case, we planned future management. A minimally invasive surgical removal procedure by an endoscopic intraoral approach from the lingual side was performed and good early recovery was noted. The resected tumor consisted of several small tooth-like structures. Histopathological diagnosis was a compound odontoma. One-year follow-up findings showed that the post-surgical course was good.

Delayed Eruption of Permanent Lower Lateral Incisor in Relation to Compound Odontoma: A Case Report.

AIM: To report a delayed tooth eruption following late surgical removal of a compound odontoma in a 10-year-old child. BACKGROUND: Odontomas are the most common odontogenic tumors. They are usually asymptomatic and discovered during routine radiographic examinations or during an assessment of delayed tooth eruption. Odontomas are classified into compound or complex based on the microscopic structure of dental tissues. Early diagnosis and surgical removal of odontomas is the keyword for favorable results. CASE DESCRIPTION: This paper describes a case of compound odontomas in a 10-year-old boy that prevented eruption of the permanent mandibular lateral incisor. Extraction of mandibular primary lateral incisors and surgical excision of the compound odontomas was performed. After 3 years of follow-up, at the age of 13 years, the permanent lateral incisor erupted and approached the occlusal plane. CONCLUSION: Late surgical removal of odontomas resulted in a delayed eruption of the affected teeth. CLINICAL SIGNIFICANCE: Surgical removal of odontomas and regular follow-up to monitor the eruption of the affected teeth should be considered for the teeth with an open apex before considering orthodontic traction.

Impactación dentaria por odontoma compuesto: reporte de caso y revisión de literatura / Dental impactation caused by odontoma: case report and literature review

Resumen Actualmente los odontomas son los tumores odontogénicos más frecuentes. Son considerados hamartomas, compuestos por células epiteliales odontogénicas y mesenquimatosas diferenciadas, y muestra tejidos dentales en su estructura. Se presenta una revisión de la literatura seguido por un reporte de caso de un odontoma compuesto en el maxilar inferior de un paciente de 13 años asociado a la inclusión del segundo molar inferior derecho (4.7). Se realizó la exéresis del tumor y la correspondiente biopsia para confirmar el diagnóstico.

Abstract At present time odontomas are the most common odontogenic tumors. They are hamartomas, composed of epithelial odontogenic and mesenchymal cells, presenting dental tissue in their structure. A literature review followed by a case report are presented. The case report presents a compound odontoma in the inferior maxillary of a 13-year-old patient, associated with the inclusion of the second right inferior molar (4.7). The exeresis followed by the biopsy of the tumor were performed to confirm the clinical diagnosis.