1.
Chemistry
; 23(2): 282-285, 2017 01 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27801951
RESUMO
An ultra-remote intramolecular (point-to-point) asymmetric control through 38â bonds (1,39-asymmetric induction) has been achieved by using the principle of direct supramolecular orientation of catalytic and reactive moieties in asymmetric autocatalysis. We found the highly stereoselective diisopropylzinc addition reaction using designed molecules possessing pyrimidine sites at each terminal of a conformationally flexible simple methylene chain.