Investigating the association between the lunar cycle and sleep, physiological, cognitive, and physical performance in children with Down syndrome.

BACKGROUND: Children with Down syndrome (DS) offer a compelling context within the fieldof human biology for examining potential lunar influences. While the exact mechanisms governing lunar effects are still under investigation, a growing body of scientific inquiry suggests possible connections between lunar phases and physiological, physical, and cognitive parameters. This investigation holds promise for uncovering the intricate interplay between lunar cycles (LCs) and the unique biology of children with DS. This study investigated the potential influence of the LC on physiological, physical, and cognitive parameters in children with DS, focusing on sleep patterns, physical performance, and cognitive abilities. MATERIALS AND METHODS: Seventeen children with DS participated in this study. Sleep data, physical performance metrics, and cognitive test results were collected throughout the LC, including the new moon (NM), first quarter, full moon (FM), and third quarter. Statistical analyses were conducted to assess the differences in these parameters across lunar phases. RESULTS: Significant differences were observed in sleep patterns, with reduced total sleep time (P < 0.01) and sleep efficiency (P < 0.001) during the FM phase. Heart rates (HRs) before (P < 0.001) and after (P < 0.01) exercise also displayed pronounced changes during LC. Additionally, the reaction time (RT) exhibited a significant difference (P < 0.01) across the lunar phases. However, physical performance metrics, including squat jump (SJ), sprint, and 6-minute walk distance (6MWD), did not show significant variations. CONCLUSION: This study suggests that LC may have a moderating effect on sleep patterns, HR, and cognitive performance in children with DS. These findings have practical implications for caregivers and educators and highlight the importance of considering lunar-associated variations in planning schedules and interventions for children with DS.

Factors influencing migration of short-finned eels (Anguilla australis) over 3 years from a wetland system, Lake Condah, south-east Australia, downstream to the sea.

Anguillid eel populations are under threat globally. A particularly vulnerable life-cycle stage is the migration of mature adult eels downstream from freshwater habitats through estuaries into the sea to spawn. This study investigated the factors associated with downstream migration of the short-finned eel Anguilla australis (Richardson 1841) from a coastal wetland (Lake Condah) in south-east Australia, using acoustic telemetry. Migration was associated with time of the year, higher water level and river flows, decreasing water temperature, and darker moon phases. Larger individuals and those in better condition were more likely to migrate from the wetland. Downstream migration peaked in spring, in contrast to the typical autumn migration period for other temperate anguillids. Variable responses, in comparison to other studies, highlight how migration cues may not be universal. In south-east Australia, short-finned eels may have evolved to migrate in multiple phases by first migrating to the estuary during typical seasonal spring flow pulses (e.g., to avoid being stranded in upland reaches during dry summer periods) and then migrating into the ocean in autumn. More research is needed to unravel these processes and causes, especially considering that the relationship between migration and hydrology may be complex and confounded (e.g., by human-induced disruptions to migratory pathways).

Small tube-nosed seabirds fledge on the full moon and throughout the lunar cycle.

Many seabirds are attracted to anthropogenic light, and the risk is greater for recent fledglings. Moon phase predicts the probability of stranding (fewer birds strand on the full moon), but it remains uncertain whether moon phase is associated with when young seabirds fledge. Fledging behaviour of nocturnal, burrowing seabirds can be difficult to monitor using traditional methods but can provide insight into environmental factors that influence the risk of stranding. We used passive integrated transponder tags to monitor the fledging dates and times of Leach's storm-petrel (Hydrobates leucorhous) chicks across four breeding seasons (2017, 2018, 2021, 2022) at a major colony in Newfoundland and Labrador, Canada. We also assessed whether moon phase and incident illumination related to fledging date and time. The median fledge time was 1.6 h after sunset (0.6-11.7 h). The median fledge date was 10 October, and fledging dates ranged from 13 September to 13 November. Most importantly, moon phase was not associated with the time and date that Leach's storm-petrel chicks fledged. These results suggest that recently fledged storm-petrels are less attracted to anthropogenic light during high levels of natural illumination, which could indicate periods of higher stranding risk and help concentrate conservation efforts.

Assessment of effects of moon phases on hospital outpatient visits: An observational national study.

Objectives: A vast amount of literature has been conducted for investigating the association of different lunar phases with human health; and it has mixed reviews for association and non-association of diseases with lunar phases. This study investigates the existence of any impact of moon phases on humans by exploring the difference in the rate of outpatient visits and type of diseases that prevail in either non-moon or moon phases. Methods: We retrieved dates of non-moon and moon phases for eight years (1st January 2001-31st December 2008) from the timeanddate.com website for Taiwan. The study cohort consisted of 1 million people from Taiwan's National Health Insurance Research Database (NHIRD) followed over eight years (1st January 2001-31st December 2008). We used the two-tailed, paired-t-test to compare the significance of difference among outpatient visits for 1229 moon phase days and 1074 non-moon phase days by using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes from NHIRD records. Results: We found 58 diseases that showed statistical differences in number of outpatient visits in the non-moon and moon phases. Conclusions: The results of our study identified diseases that have significant variations during different lunar phases (non-moon and moon phases) for outpatient visits in the hospital. In order to fully understand the reality of the pervasive myth of lunar effects on human health, behaviors and diseases, more in-depth research investigations are required for providing comprehensive evidence covering all the factors, such as biological, psychological and environmental aspects.

Is there an association between the lunar phases and hospital admission for different episode types in bipolar disorder? A retrospective study in northern China.

The effects of the moon on mental activities remain contentious. Few studies have investigated associations between lunar phases and different types of bipolar disorder (BD) episodes. In the current study, 7,452 patients with BD from three hospitals were enrolled. Patients were divided into two groups on the basis of episode types, and the effects of lunar phase were examined for each type. The cosinor analysis revealed moon-related rhythmicity in admissions for BD in a period of 14.75 days. There were fewer admissions around the new moon and the full moon. There was no significant difference between different groups in acrophase. There was possibly a temporal lag between the onset of BD and hospitalization. Thus, it is too early to draw firm conclusions about the impact of lunar phases on BD. Sleep might be a middle way from moon effect to admissions of BD. These results have implications for future disease prevention strategies and research.

Lunar Cycle, Climate, and Onset of Parturition in Domestic Dromedary Camels: Implications of Species-Specific Metabolic Economy and Social Ecology.

Given energy costs for gestating and caring for male offspring are higher than those of female newborns, external environmental conditions might be regarded as likely to affect the timing of delivery processes differentially depending on the sex of the newborn calf to be delivered. The aim of the present paper is to evaluate the association between environmental stressors such as the moon phase and weather-related factors and the onset of labor in female dromedaries. A binary logistic regression model was developed to find the most parsimonious set of variables that are most effective in predicting the probability for a gravid female dromedary to give birth to a male or a female calf, assuming that higher gestational costs and longer labor times are ascribed to the production of a male offspring. Although the differences in the quantitative distribution of spontaneous onset of labor across lunar phases and the mean climate per onset event along the whole study period were deemed nonsignificant (p > 0.05), a non-negligible prediction effect of a new moon, mean wind speed and maximum wind gust was present. At slightly brighter nights and lower mean wind speeds, a calf is more likely to be male. This microevolutionary response to the external environment may have been driven by physiological and behavioral adaptation of metabolic economy and social ecology to give birth to cooperative groups with the best possible reduction of thermoregulatory demands. Model performance indexes then highlighted the heterothermic character of camels to greatly minimize the impact of the external environment. The overall results will also enrich the general knowledge of the interplay between homeostasis and arid and semi-arid environments.

A Markov Chain Monte Carlo (MCMC) Multivariate Analysis of the Association of Vital Parameter Variation With the Lunar Cycle in Patients Hospitalized With COVID-19.

INTRODUCTION: Over the last three years, the world has been battling a long-drawn pandemic resulting from the coronavirus outbreak. Despite the safety measures, there have been multiple pandemic waves happening throughout the world. Therefore, it is necessary to understand the fundamental characteristics of COVID-19 transmission and pathogenesis to overcome the threat of the pandemic. This study focused on hospitalized COVID-19 patients because of their high mortality rate, which indicates the need to improve inpatient management. METHODS: Based on the cyclic nature of the pandemic, observations were made to examine the influence of lunar phases on six vital parameters of COVID-19 patients. A multivariate analysis was carried out to study the interactions of lunar phase pairwise on COVID-19 statuses and COVID-19 status pairwise on lunar phases by treating six vital parameters as independent entities. RESULTS: The results of multivariate analysis on the data of 215,220 vital values showed that lunar phases are associated with trends in variations in the vital parameters of COVID-19-infected patients. CONCLUSION: In summary, our results show that patients infected with COVID-19 appear to be more susceptible to lunar influence compared to non-COVID-19 patients. Furthermore, this study shows a vital parameter destabilization window (DSW) that can help identify which hospitalized COVID-19 patients can recover. Our pilot study forms the basis for future studies to eventually establish the incorporation of variation of vital signs with the lunar cycle into the standard of care for COVID-19 patients.

Evidence of circalunar rhythmicity in young children's evening melatonin levels.

In adults, recent evidence demonstrates that sleep and circadian physiology change across lunar phases, including findings that endogenous melatonin levels are lower near the full moon compared to the new moon. Here, we extend these results to early childhood by examining circalunar fluctuations in children's evening melatonin levels. We analysed extant data on young children's circadian rhythms (n = 46, aged 3.0-5.9 years, 59% female). After following a strict sleep schedule for 5-7 days, children completed an in-home, dim-light circadian assessment (<10 lux). Salivary melatonin was assessed at regular 20- to 30-min intervals until 1 h past each child's scheduled bedtime. Melatonin levels varied significantly across lunar phases, such that melatonin was lower in participants assessed near the full moon as compared to near the new moon. Significant differences were observed at 50 min (meanfull  = 2.5 pg/ml; meannew  = 5.4 pg/ml) and 10 min (meanfull  = 7.3 pg/ml; meannew  = 15.8 pg/ml) before children's scheduled bedtime, as well as at 20 min (meanfull  = 15.5 pg/ml; meannew  = 26.1 pg/ml) and 50 min (meanfull  = 19.9 pg/ml; meannew  = 34.3 pg/ml) after bedtime. To our knowledge, these are the first data demonstrating that melatonin secretion, a process regulated by the human circadian system, is sensitive to changes in lunar phase at an early age. Future research is needed to understand the mechanisms underlying this association (e.g., an endogenous circalunar rhythm) and its potential influence on children's sleep and circadian health.

Role of tide and lunar phases on the migration pattern of juvenile Hilsa shad (Tenualosa ilisha) within a meso-macrotidal estuary.

Tide and lunar phases often influence the behaviour and life cycle of different fishes, especially migratory species. In the Hooghly River estuary, Hilsa shad is an anadromous fish species that migrates from the adjacent sea to the estuary and rivers for spawning. After spawning, the juveniles remain in the rivers and estuary for few months then start their downstream migration towards the adjacent sea. However, the pattern of their downstream migration has not been studied in detail so far. This study investigates the role of tide and lunar phases on the juvenile Hilsa shad migration pattern. In this study, we have estimated the rate of juveniles migrating through the river channel (no. m-2  h-1 ) during high tide and low tide in all of the lunar phases. The number of juvenile Hilsa shad fishes is found to be much higher during low tides in most of the observations and there is a significant difference (t = 11.904, P < 0.001) between the high tide and low tide catches in the entire study region. Among the eight lunar phases, the number of juveniles is also observed to be higher during the new moon and full moon, and there is also a significant difference in juvenile catch among the lunar phases (F = 64.372, P < 0.001) in the entire stretch of the study area. These observations enabled us to develop a plausible mechanism of the downstream migration of Hilsa shad juveniles.

Effect of meteorological factors and lunar phases on occurrence of psychogenic nonepileptic seizures.

BACKGROUND: Psychogenicnonepilepticseizures (PNES) lack the abnormal electrographical discharges in electroencephalogram seen in epileptic seizures. The notion of the effects of meteorological factors and lunar phases onoccurrence of seizures in patients with PNES has been the subject of very few research studies and the available evidence in the literature is equivocal. In this study, we aimed to study the influence oflunarphases and meteorological factors on the frequency of PNES and its semiological categories. METHODS: We retrospectively reviewed the medical records of patients discharged with a diagnosis of PNES from our epilepsy monitoring unit in a 3-year period. The 119 patients who met the inclusion criteria were categorized into hypermotor, hypomotor, or intact sensorium based on semiology of their seizures. The occurrence of PNES, in total and in each semiological category, was correlated with the daily average temperature, atmospheric pressure, and the 4 lunar phases. RESULTS: There were 31.8% and 11.1% more-than-expected captured seizures when the average daily atmospheric pressure was lower or higher, respectively, of what is generally considered a comfortable atmospheric pressure. No consistent relation was found between the full moon phases and occurrence of PNES. CONCLUSION: A significant association between atmospheric pressure and the occurrence of nonepileptic seizures was found, whereas no consistent increase in PNES was observed during the full moon phases. There is still an open debate about the effect of the lunar phases on human behavior and neurological disorders such as PNES.

Does lunar cycle affect biological parameters in young healthy men?

This study aimed to assess the effects of the lunar cycle on diurnal variation of biological, i.e, hormonal, biochemical, and hematological, profiles of diurnally active healthy men. Blood samples of 20 males were collected on four occasions [full moon (FM) and new moon (NM), in the morning (06:00-07:00 h) and evening (19:00-20:00 h)]. The results showed that melatonin and testosterone levels and neutrophils count were lower during the FM as compared to the NM in the morning (p < .001; d = 4.13, p < .001; d = 3.84, p < .01; d = 0.77, respectively) and evening (p < .001; d = 6.36, p < .001; d = 4.03, p < .05; d = 1.07, respectively) samples. However, cortisol level was higher during the FM compared to the NM, in the morning (p < .001; d = 0.74) and evening (p < .001; d = 3.54). Hemoglobinemia was higher only in the evening during the FM compared to the evening of the NM (p < .01; d = 1.22). In summary, this study confirmed that lunar cycle can affect human biological parameters independently of time of day.

Effects of lunar cycle on fasting plasma glucose, heart rate and blood pressure in type 2 diabetic patients.

The purpose of this study was to investigate the influence of lunar phases on fasting plasma glucose, heart rate, and blood pressure in type 2 diabetic patients. The present cross-sectional study was carried out during four phases, i.e., full moon (FM), first quarter (FQ), new moon (NM), and third quarter (TQ), of the lunar month. The study was conducted on 42 randomly selected patients (22 males and 20 females) from the Diabetes Clinic of Calcutta Medical College. Fasting plasma glucose (FPG) of each subject was determined and heart rate (HR) and blood pressure (BP) were measured at rest and during static exercise conditions, i.e., performance of a standard handgrip dynamometer test. The FPG level during the NM and FM was significantly higher (p < .001) than during the TQ and FQ for both males and females, respectively. The mean HR during static exercise during the NM and FM for both males and females was significantly higher than that during the FQ (p < .05) and TQ (p < .01). It appears from the present study that lunar phases may affect fasting plasma glucose level and cardiovascular functions of aged type 2 diabetic patients both at rest and during exercise.

Lunar cycle and psychiatric hospital admissions for schizophrenia: new findings from Henan province, China.

Objective: Findings on the effect of the lunar cycle on mental illness are conflicting. We investigated the association between the lunar cycle and a number of psychiatric presentations of schizophrenia and determined which subtypes were susceptible to lunar phases.Methods: We evaluated 13,067 patients admitted to Zhumadian Psychiatric Hospital between January 1, 2012, and December 31, 2017 (73 lunar cycles). Patients were retrospectively assigned to lunar phase based on their admission date: new moon +/- 1 day, first quarter +/- 1 day, full moon +/- 1 day, and third quarter +/- 1 day. The International Statistical Classification of Diseases, 10th revision (ICD-10), was used for diagnosis. We used a Chi-squared goodness of fit test to evaluate the distribution of admissions across the lunar phase and R*C Chi-squared tests to compare age, sex, birth season, and clinical subtype distributions by phase. We used multiple logistic regression to further identify the relationship between clinical subtype and lunar phase.Results: Psychiatric admissions for schizophrenia varied significantly across the lunar cycle (χ2 = 36.400, p< .0001), peaking in the first quarter, followed by the full moon, and lowest at the new moon. Using unspecified schizophrenia (F20.9) as reference, people with paranoid schizophrenia (F20.0) were more likely to be admitted in the full moon than in other phases (odds ratio: 1.157, 95% confidence interval: 1.040-1.286) (p < .05); other subtypes showed no admission differences during the four lunar phases (p > .05).Conclusions: Psychiatric admissions for schizophrenia show lunar periodicities. People with schizophrenia tend to be stable in the new moon, but their condition is easily aggravated during the first quarter and full moon. Patients with paranoid schizophrenia are more susceptible to deterioration at the full moon, so merit more attention and care from communities, families, and hospitals.

Impact of lunar phase on outcomes following ST-elevation myocardial infarction.

BACKGROUND: There is a long-held belief in the association between the full moon and extremes of human behaviour and adverse health consequences. Small-scale studies are conflicting; however, most suggest no clear association between lunar phase and occurrence of acute coronary syndromes. AIMS: To evaluate the impact of the lunar phase, and in particular, the full moon phase, on the incidence and outcomes among ST-elevation myocardial infarction (STEMI) cases undergoing percutaneous coronary intervention (PCI). METHODS: We conducted a multi-centre retrospective study from the Melbourne Interventional Group registry, including 7570 STEMI cases from six tertiary centres over a 12-year study period in Victoria, Australia, and performed statistical analysis using Stata software. Primary outcomes studied were the incidence of STEMI, the occurrence of major adverse cardiac and cerebrovascular events and mortality at 1 and 5 years in cases of STEMI undergoing primary or rescue percutaneous coronary intervention during the full moon between 2005 and 2017 in Victoria, Australia. RESULTS: This study demonstrated neither significant difference in STEMI incidence (P = 0.61) nor of major adverse cardiovascular events across all lunar phases. Subgroup analysis confirmed no difference in outcomes during the full moon compared to a composite of other lunar phases.Kaplan-Meier survival estimates showed similar 30-day outcomes across lunar phases (P = 0.35) and when comparing full moon to a composite of other lunar phases (P = 0.45). Similarly, there was no significant difference in survival at 1 and 5 years between lunar phases (P = 0.68) or compared to the full moon phase (P = 0.51). CONCLUSIONS: This study showed no significant difference in the incidence or cardiovascular outcomes and survival in patients with STEMI undergoing primary or rescue percutaneous coronary intervention during the lunar phases.

Correlation between the Lunar Phase and Tail-Lifting Behavior of Lizards (Pogona vitticeps) Exposed to an Extremely Low-Frequency Electromagnetic Field.

We previously showed that the agamid lizard Pogona vitticeps responded to an extremely low-frequency electromagnetic field (ELF-EMF; frequency: 6 and 8 Hz; peak magnetic field: 2.6 µT; peak electric field: 10 V/m) with tail-lifting behavior. In addition, the tail-lifting response to ELF-EMF disappeared when the parietal eyes of the lizards were covered by small round aluminum caps. This result suggests that the parietal eye contributes to light-dependent magnetoreception. In the present study, we set up an ELF-EMF group to evaluate the long-term effect of the ELF-EMF on lizards' behavior and examine our hypothesis that exposure to ELF-EMFs increases the magnetic field sensitivity in lizards. We therefore include the lunar phase (full moon/new moon) and K index as environmental factors related to the geomagnetic field in the analysis. The number of tail lifts per individual per day was the response variable while calendar month, daily mean temperature, daily mean humidity, daily mean atmospheric pressure, full moon, new moon, and K index were the explanatory variables. We analyzed an ELF-EMF group and a control group separately. In a multiple linear regression analysis, the independent determinants associated with the number of tail lifts were the full moon, the temperature, February, March, April, and May in the ELF-EMF group and March, April, May, and June in the control group. The P. vitticeps in the ELF-EMF group responded to the full moon whereas those in the control group did not. In addition, in the ELF-EMF group, the number of tail lifts was higher on days when the K index was higher (P = 0.07) in the first period whereas there was no such tendency in either period in the control group. There is the possibility that the exposure to ELF-EMFs may increase magnetic-field sensitivity in lizards.

Actividad de un "ensamblaje" de murciélagos en el norte de Brasil (Mammalia: Chiroptera) / Activity of a bat assemblage in northern Brazil (Mammalia: Chiroptera)

Resumen La Amazonía es uno de los ecosistemas tropicales más biodiversos del mundo, característica atribuida a la complejidad estructural que le brinda la geología y la gran riqueza de sus suelos. Los murciélagos constituyen uno de los taxones de la clase Mammalia mejor representados en esta región, aun así, existen claros vacíos de conocimiento, principalmente, respecto a su ecología, con lo cual, en el presente estudio se pretende evaluar la influencia que tienen factores ambientales, como la temporada climática, temperatura (máxima y mínima), humedad relativa y porcentaje de fase iluminada de la Luna, en los patrones de actividad (riqueza, abundancia y gremios tróficos) de un ensamblaje de murciélagos en la Amazonía central brasilera. El estudio fue llevado a cabo en dos municipios del estado de Rondônia, empleando ocho redes de niebla, durante 62 noches de muestreo, abarcando las temporadas lluviosa y seca. En total fueron capturados 2 499 individuos de 58 especies, la familia mejor representada fueron los Phyllostomidae, mientras que la especie que registró la mayor frecuencia de capturas fue Carollia perspicillata (N = 859), seguida de C. brevicauda (N = 209). No se presentaron diferencias entre la estructura del ensamblaje considerando la temporada climática (lluviosa-seca), sin embargo, durante la temporada seca se registró un mayor número de especies e individuos (57 especies, N = 1 597), que en la temporada lluviosa (44 especies, N = 902). La abundancia de murciélagos estuvo influenciada principalmente, por la humedad relativa (P = 0.00) y la temperatura (mínima) (P = 0.04), mientras que, las especies respondieron diferencialmente al porcentaje de fase iluminada de la luna. En estos resultados se evidencia la influencia de factores ambientales en los patrones de actividad del ensamblaje de murciélagos en la Amazonía, en donde la ecología de las especies determina el tipo de influencia. Sin embargo, se requieren de estudios llevados a cabo por períodos más prolongados, para determinar si estos patrones se mantienen a lo largo del tiempo.(AU)

Abstract The Amazon is considered one of the most biodiverse tropical ecosystems in the world thanks to the structural complexity that geology offers and the great biological richness of its soils. Further, concerning the Mammalian class, bats are one of the best represented taxa in the region, nevertheless their ecology is poorly studied. This study, evaluates the influence of environmental factors such as the climate season, temperature (maximum and minimum), relative humidity and lunar phase on the activity patterns (abundance and trophic guilds) of an assemblage of bats in the Brazilian central Amazon. This study was carry out in two municipalities of the state of Rondônia using eight mist nets during 62 nights of sampling, covering humid and dry periods. A total of 2 499 individuals of 58 species were captured. The best represented family was the Phyllostomidae, while the species that recorded the highest frequency of captures was Carollia perspicillata (N = 859), followed by C. brevicauda(N = 209). There were no significant differences between the structure of the assemblage considering the climatic season (rain-dry). However, during the dry season a greater number of species and individuals was recorded (57 species, N = 1 597) than in the rainy season (44 species, N = 902). The abundance of bats was influenced mainly by relative humidity (P = 0.00) and minimal temperature (P = 0.04), while the species responded differentially to the lunar phase. These results show the influence of environmental factors on the activity patterns of a bat assemblage in the Amazon, where the factors that influence them depends on the ecology of each species. However, studies carried out for longer periods are required to determine if these patterns are maintained over time.(AU)

No association of moon phase with stroke occurrence.

Stroke occurrence shows strong correlations with sleep disorders and even subtle sleep disturbances have been shown to affect ischemic stroke (IS) occurrence. Chronobiology also exerts effects, like the morning surge in IS occurrence. Lunar cycles have also been shown to affect sleep and other physiological processes, but studies on moon phases and its possible association with occurrence of stroke are rare and nonconclusive. Therefore, we studied the effects of moon phases on stroke hospitalizations and in-hospital mortality nationwide in Finland in 2004-2014. All patients aged ≥18 years with IS or intracerebral hemorrhage (ICH) as primary discharge diagnosis were included. Daily number of admissions was treated as a response variable while moon phase, year and astronomical season were independent variables in Poisson regression modeling. We found no association between moon phases and stroke occurrence. The overall occurrence rates did not vary between different moon phases for IS or ICH (p = 0.61 or higher). There were no differences between moon phases in daily admission rates among men, women, young and old patients for any of the stroke subtypes. There was no difference in in-hospital mortality with regard to moon phase for IS or ICH overall (p = 0.19 or higher), nor in subgroup analyses. There were no significant interactions between moon phase and astronomical season for stroke occurrence or in-hospital mortality. To conclude, in this over a decade-long nationwide study including a total of 46 million person years of follow-up, we found no association between moon phases and occurrence or in-hospital mortality rates of IS or intracerebral hemorrhage.

Lunar cycle may have an effect on Shock Wave Lithotripsy related pain outcome.

OBJECTIVES: We tried to investigate the effects of lunar phase on Shock Wave Lithotripsy (SWL) related pain. In addition, correlation of various clinical parameters with the pain perception during SWL procedure, were also investigated. METHODS: A total of 378 patients who underwent first SWL sessions for renal or ureteral stones were prospectively enrolled in the study. The degree of pain perception during the procedure was evaluated with 10-point visual analog scale (VAS) and pain questionnaires. The date of SWL was allocated to dates and times of lunar phases as: newmoon, waxing crescent, first quarter, waxing gibbus, fullmoon, waning gibbus, last quarter and waning gibbus. RESULTS: Mean VAS scores in first quarter (2,41±1,06) were significantly lower when compared to mean VAS scores in waning crescent (3,58±1,83) and waning gibbus (3,42±1,98) (p=0,005 and 0,041, respectively). No statistically significant differences were observed when other lunar phases were compared between each other. Mean pain scores were not affected from gender, age, body mass index (BMI) and stone characteristics (stone laterality, burden and location). CONCLUSIONS: SWL procedure performed in first quarter of the lunar phase may become less painful. To the best of our knowledge, this is the first study which evaluated the effect of lunar phase on post-SWL pain outcome. Thus, additional randomized studies with larger series may be more informative.

Effect of lunar phase on frequency of psychogenic nonepileptic events in the EMU.

INTRODUCTION: Studies of the effect of a full moon on seizures have yielded mixed results, despite a continuing prevailing belief regarding the association of lunar phase with human behavior. The potential effect of a full moon on psychogenic nonepileptic events has not been as well studied, despite what anecdotal accounts from most epilepsy monitoring unit (EMU) staff would suggest. METHODS: We obtained the dates and times of all events from patients diagnosed with psychogenic nonepileptic events discharged from our EMU over a two-year period. The events were then plotted on a 29.5-day lunar calendar. Events were also broken down into lunar quarters for statistical analysis. RESULTS: We found a statistically significant increase in psychogenic nonepileptic events during the new moon quarter in our EMU during our studied timeframe. CONCLUSION: Our results are not concordant with the results of a similarly designed past study, raising the possibility that psychogenic nonepileptic events are not influenced by lunar phase.

The influence of lunar phases and zodiac sign 'Leo' on perioperative complications and outcome in elective spine surgery.

BACKGROUND: Many people believe that the moon has an influence on daily life, and some even request elective surgery dates depending on the moon calendar. The aim of this study was to assess the influence of 'unfavorable' lunar or zodiac constellations on perioperative complications and outcome in elective surgery for degenerative disc disease. METHODS: Retrospective database analysis including 924 patients. Using uni- and multivariate logistic regression, the likelihood for intraoperative complications and re-do surgeries as well as the clinical outcomes at 4 weeks was analyzed for surgeries performed during the waxing moon, full moon, and dates when the moon passed through the zodiac sign 'Leo.' RESULTS: In multivariate analysis, patients operated on during the waxing moon were 1.54 times as likely as patients who were operated on during the waning moon to suffer from an intraoperative complication (OR 1.54, 95 % CI 1.07-2.21, p = 0.019). In contrast, there was a trend toward fewer re-do surgeries for surgery during the waxing moon (OR 0.51, 95 % CI 0.23-1.16, p = 0.109), while the 4-week responder status was similar (OR 0.73, 95 % CI 0.47-1.14, p = 0.169). A full moon and the zodiac sign Leo did not increase the likelihood for complications, re-do surgeries or unfavorable outcomes. CONCLUSIONS: We found no influence of 'unfavorable' lunar or zodiac constellations on the 4-week responder status or the revision rate that would justify a moon calendar-based selection approach to elective spine surgery dates. However, the fact that patients undergoing surgery during the waxing moon were more likely to suffer from an intraoperative complication is a surprising curiosity and defies our ability to find a rational explanation.