Observation of Chirality Transfer in Twisted Few-Layer Graphene.

Chiral materials are the focus of research in a variety of fields such as chiroptical sensing, biosensing, catalysis, and spintronics. Twisted two-dimensional (2D) materials are rapidly developing into a class of atomically thin chiral materials that can be effectively modulated through interlayer twist. However, chirality transfer in chiral 2D materials has not been reported. Here, we show that the chirality from the twist interface of graphene can directly transfer to achiral few-layer graphene and lead to a strong chiroptical response probed with circularly polarized Raman spectroscopy. Distinct Raman optical activity (ROA) for the interlayer shear modes in achiral few-layer graphene is observed, with the degree of polarization reaching as high as 0.5. These findings demonstrate the programmability of chiroptical response through stacking and twist engineering in 2D materials and offer insights into the transfer of chirality in atomically thin chiral materials for optical and electronic applications.

SQUID magnetoneurography: an old-fashioned yet new tool for noninvasive functional imaging of spinal cords and peripheral nerves.

We are engaged in the development and clinical application of a neural magnetic field measurement system that utilizes biomagnetic measurements to observe the activity of the spinal cord and peripheral nerves. Unlike conventional surface potential measurements, biomagnetic measurements are not affected by the conductivity distribution within the body, making them less influenced by the anatomical structure of body tissues. Consequently, functional testing using biomagnetic measurements can achieve higher spatial resolution compared to surface potential measurements. The neural magnetic field measurement, referred to as magnetoneurography, takes advantage of these benefits to enable functional testing of the spinal cord and peripheral nerves, while maintaining high spatial resolution and noninvasiveness. Our magnetoneurograph system is based on superconducting quantum interference devices (SQUIDs) similar to the conventional biomagnetic measurement systems. Various design considerations have been incorporated into the SQUID sensor array structure and signal processing software to make it suitable for detecting neural signal propagation along spinal cord and peripheral nerve. The technical validation of this system began in 1999 with a 3-channel SQUID system. Over the course of more than 20 years, we have continued technological development through medical-engineering collaboration, and in the latest prototype released in 2020, neural function imaging of the spinal cord and peripheral nerves, which could also be applied for the diagnosis of neurological disorders, has become possible. This paper provides an overview of the technical aspects of the magnetoneurograph system, covering the measurement hardware and software perspectives for providing diagnostic information, and its applications. Additionally, we discuss the integration with a helium recondensing system, which is a key factor in reducing running costs and achieving practicality in hospitals.

Quantum Interference Enhancement of the Spin-Dependent Thermoelectric Response.

We investigate the influence of quantum interference (QI) and broken spin-symmetry on the thermoelectric response of node-possessing junctions, finding a dramatic enhancement of the spin-thermopower (Ss), figure-of-merit (ZsT), and maximum thermodynamic efficiency (ηsmax) caused by destructive QI. Using many-body and single-particle methods, we calculate the response of 1,3-benzenedithiol and cross-conjugated molecule-based junctions subject to an applied magnetic field, finding nearly universal behavior over a range of junction parameters with Ss, ZsT, and reaching peak values of 2π/3(k/e), 1.51, and 28% of Carnot efficiency, respectively. We also find that the quantum-enhanced spin-response is spectrally broad, and the field required to achieve peak efficiency scales with temperature. The influence of off-resonant thermal channels (e.g., phonon heat transport) on this effect is also investigated.

Thermoelectric Properties of Porphyrin Nano Rings: A Theoretical and Modelling Investigation.

Propagation of De Broglie waves through nanomolecular junctions is greatly affected by molecular topology changes, which in turn plays a key role in determining the electronic and thermoelectric properties of source|molecule|drain junctions. The probing and realization of the constructive quantum interference (CQI) and a destructive quantum interference (DQI) are well established in this work. The critical role of quantum interference (QI) in governing and enhancing the transmission coefficient T(E), thermopower (S), power factor (P) and electronic figure of merit (ZelT) of porphyrin nanorings has been investigated using a combination of density functional theory (DFT) methods, a tight binding (Hückel) modelling (TBHM) and quantum transport theory (QTT). Remarkably, DQI not only dominates the asymmetric molecular pathways and lowering T(E), but also improves the thermoelectric properties.

Dynamics of Dispersive Measurements of Flux-Qubit States: Energy-Level Splitting Connected to Quantum Wave Mechanics.

Superconducting flux qubits have many advantages as a storage of quantum information, such as broad range tunability of frequency, small-size fabricability, and high controllability. In the flux qubit-oscillator, qubits are connected to SQUID resonators for the purpose of performing dispersive non-destructive readouts of qubit signals with high fidelity. In this work, we propose a theoretical model for analyzing quantum characteristics of a flux qubit-oscillator on the basis of quantum solutions obtained using a unitary transformation approach. The energy levels of the combined system (qubit + resonator) are analyzed in detail. Equally spaced each energy level of the resonator splits into two parts depending on qubit states. Besides, coupling of the qubit to the resonator brings about an additional modification in the split energy levels. So long as the coupling strength and the tunnel splitting are not zero but finite values, the energy-level splitting of the resonator does not disappear. We conclude that quantum nondemolition dispersive measurements of the qubit states are possible by inducing bifurcation of the resonator states through the coupling.

Role of optically pumped magnetometers in presurgical epilepsy evaluation: Commentary of the American Clinical Magnetoencephalography Society.

One of the major challenges of modern epileptology is the underutilization of epilepsy surgery for treatment of patients with focal, medication resistant epilepsy (MRE). Aggravating this distressing failure to deliver optimum care to these patients is the underuse of proven localizing tools, such as magnetoencephalography (MEG), a clinically validated, non-invasive, neurophysiological method used to directly measure and localize brain activity. A sizable mass of published evidence indicates that MEG can improve identification of surgical candidates and guide pre-surgical planning, increasing the yield of SEEG and improving operative outcomes. However, despite at least 10 common, evidence supported, clinical scenarios in MRE patients where MEG can offer non-redundant information and improve the pre-surgical evaluation, it is regularly used by only a minority of USA epilepsy centers. The current state of the art in MEG sensors employs SQUIDs, which require cooling with liquid helium to achieve superconductivity. This sensor technology has undergone significant generational improvement since whole head MEG scanners were introduced around in 1990s, but still has limitations. Further advances in sensor technology which may make ME G more easily accessible and affordable have been eagerly awaited, and development of new techniques should be encouraged. Of late, optically pumped magnetometers (OPMs) have received considerable attention, even prompting some potential acquisitions of new MEG systems to be put on hold, based on a hope that OPMs will usher in a new generation of MEG equipment and procedures. The development of any new clinical test used to guide intracranial EEG monitoring and/or surgical planning must address several specific issues. The goal of this commentary is to recognize the current state of OPM technology and to suggest a framework for it to advance in the clinical realm where it can eventually be deemed clinically valuable to physicians and patients. The American Clinical MEG Society (ACMEGS) strongly supports more advanced and less expensive technology and looks forward to continuing work with researchers to develop new sensors and clinical devices which will improve the experience and outcome for patients, and perhaps extend the role of MEG. However, currently, there are no OPM devices ready for practical clinical use. Based on the engineering obstacles and the clinical tradeoffs to be resolved, the assessment of experts suggests that there will most likely be another decade relying solely on "frozen SQUIDs" in the clinical MEG field.

Atomic-Scale Andreev Probe of Unconventional Superconductivity.

Recent emergence of low-dimensional unconventional superconductors and their exotic interface properties calls for new approaches to probe the pairing symmetry, a fundamental and frequently elusive property of the superconducting condensate. Here, we introduce the unique capability of tunneling Andreev reflection (TAR) to probe unconventional pairing symmetry, utilizing the sensitivity of this technique to specific Andreev reflections. Specifically, suppression of the lowest-order Andreev reflection due to quantum interference but emergence of the higher-order Andreev processes provides direct evidence of the sign-changing order parameter in the paradigmatic FeSe superconductor. TAR spectroscopy also reveals two superconducting gaps, points to a possibility of a nodal gap structure, and directly confirms that superconductivity is locally suppressed along the nematic twin boundary, with preferential and near-complete suppression of the larger energy gap. Our findings therefore enable new, atomic-scale insight into microscopic, inhomogeneous, and interfacial properties of emerging quantum materials.

Manipulating Quantum Interference between σ and π Orbitals in Single-Molecule Junctions via Chemical Substitution and Environmental Control.

Understanding and manipulating quantum interference (QI) effects in single molecule junction conductance can enable the design of molecular-scale devices. Here we demonstrate QI between σ and π molecular orbitals in an ∼4 Å molecule, pyrazine, bridging source and drain electrodes. Using single molecule conductance measurements, first-principles analysis, and electronic transport calculations, we show that this phenomenon leads to distinct patterns of electron transport in nanoscale junctions, such as destructive interference through the para position of a six-membered ring. These QI effects can be tuned to allow conductance switching using environmental pH control. Our work lays out a conceptual framework for engineering QI features in short molecular systems through synthetic and external manipulation that tunes the energies and symmetries of the σ and π channels.

Edge Channel Transmission through a Quantum Point Contact in the Two-Dimensional Topological Insulator Cadmium Arsenide.

Cadmium arsenide (Cd3As2) thin films feature a two-dimensional topological insulator (2D TI) phase for certain thicknesses, which theoretically hosts a set of counterpropagating helical edge states that are characteristic of a quantum spin Hall (QSH) insulator. In devices containing electrostatically defined junctions and for magnetic fields below a critical value, chiral edge modes of the quantum Hall effect can coexist with QSH-like edge modes. In this work, we use a quantum point contact (QPC) device to characterize edge modes in the 2D TI phase of Cd3As2 and to understand how they can be controllably transmitted, which is important for use in future quantum interference devices. We investigate equilibration among both types of modes and find non-spin-selective equilibration. We also demonstrate the effect of the magnetic field on suppressing equilibration. We discuss the potential role of QSH-like modes in a transmission pathway that precludes full pinch-off.

The effect of side substitution and quantum interference on the performance of molecular thermoelectric devices: a brief review.

In recent years, researchers have shown great interest in organic thermoelectric materials that are economical, efficient, lightweight, and environmentally friendly. With advancements in experimental measurement techniques and theoretical calculations, investigations of the thermoelectric properties of molecular devices have become feasible. To regulate the thermoelectric properties of molecular devices, many strategies have been proposed. In this work, we review the theoretical analytical and experimental research methods used to study these properties. We then focus on two tuning strategies, side substitution, and quantum interface effects, which have demonstrated significant improvements in the thermoelectric performance of molecular devices. Finally, we discuss the challenges faced in experimental and theoretical studies and the future prospects of molecular thermoelectric devices.

Generating optical cat states via quantum interference of multi-path free-electron-photons interactions.

The novel quantum effects induced by the free-electron-photons interaction have attracted increasing interest due to their potential applications in ultrafast quantum information processing. Here, we propose a scheme to generate optical cat states based on the quantum interference of multi-path free-electron-photons interactions that take place simultaneously with strong coupling strength. By performing a projection measurement on the electron, the state of light changes significantly from a coherent state into a non-Gaussian state with either Wigner negativity or squeezing property, both possess metrological power to achieve quantum advantage. More importantly, we show that the Wigner negativity oscillates with the coupling strength, and the optical cat states are successfully generated with high fidelity at all the oscillation peaks. This oscillation reveals the quantum interference effect of the multiple quantum pathways in the interaction of the electron with photons, by that various nonclassical states of light are promising to be fast prepared and manipulated. These findings inspire further exploration of emergent quantum phenomena and advanced quantum technologies with free electrons.

Alignment of magnetic sensing and clinical magnetomyography.

Neuromuscular diseases are a prevalent cause of prolonged and severe suffering for patients, and with the global population aging, it is increasingly becoming a pressing concern. To assess muscle activity in NMDs, clinicians and researchers typically use electromyography (EMG), which can be either non-invasive using surface EMG, or invasive through needle EMG. Surface EMG signals have a low spatial resolution, and while the needle EMG provides a higher resolution, it can be painful for the patients, with an additional risk of infection. The pain associated with the needle EMG can pose a risk for certain patient groups, such as children. For example, children with spinal muscular atrophy (type of NMD) require regular monitoring of treatment efficacy through needle EMG; however, due to the pain caused by the procedure, clinicians often rely on a clinical assessment rather than needle EMG. Magnetomyography (MMG), the magnetic counterpart of the EMG, measures muscle activity non-invasively using magnetic signals. With super-resolution capabilities, MMG has the potential to improve spatial resolution and, in the meantime, address the limitations of EMG. This article discusses the challenges in developing magnetic sensors for MMG, including sensor design and technology advancements that allow for more specific recordings, targeting of individual motor units, and reduction of magnetic noise. In addition, we cover the motor unit behavior and activation pattern, an overview of magnetic sensing technologies, and evaluations of wearable, non-invasive magnetic sensors for MMG.

Development of an HTS-SQUID-Based Receiver for Long-Range Magnetic Induction Communication in Extreme Environments.

The communication range of magnetic-induction (MI) technology in extreme environments such as underwater or underground is limited by the dipole-like attenuation behavior of the magnetic field as well as the eddy current induced loss in conductive media, and therefore a highly sensitive receiver is generally required. In this work, we propose the use of a highly sensitive superconducting quantum interference device (SQUID) in MI communication and try to provide a comprehensive investigation on developing a SQUID-based receiver for practical MI applications. A portable receiver scheme integrating a SQUID sensor and a coil-based flux transformer was proposed. The high sensitivity and long-range communication capability of the proposed receiver was experimentally demonstrated by spectroscopic measurements and reception experiments on a receiver prototype. Based on the experimental demonstrations, the sensitivity optimization of the proposed scheme was further investigated by simulation studies, which suggest that a communication distance exceeding 100 m and a channel capacity of ∼20 kb/s in underwater environment could be achieved based upon the optimization of the developed prototype. The results presented in this work have highlighted the potential of deploying SQUID sensors for long-range MI applications in extreme environments.

Eliminating temporal correlation in quantum-dot entangled photon source by quantum interference.

Semiconductor quantum dots, as promising solid-state platform, have exhibited deterministic photon pair generation with high polarization entanglement fidelity for quantum information applications. However, due to temporal correlation from inherently cascaded emission, photon indistinguishability is limited, which restricts their potential scalability to multi-photon experiments. Here, by utilizing quantum interferences to decouple polarization entanglement from temporal correlation, we improve four-photon Greenberger-Horne-Zeilinger (GHZ) state entanglement fidelity from (58.7±2.2)% to (75.5±2.0)%. Our work paves the way to realize scalable and high-quality multi-photon states from quantum dots.

Switching Quantum Interference in Single-Molecule Junctions by Mechanical Tuning.

The charge transport through single-molecule electronic devices can be controlled mechanically by changing the molecular geometrical configuration in situ, but the tunable conductance range is typically less than two orders of magnitude. Herein, we proposed a new mechanical tuning strategy to control the charge transport through the single-molecule junctions via switching quantum interference patterns. By designing molecules with multiple anchoring groups, we switched the electron transport between the constructive quantum interference (CQI) pathway and the destructive quantum interference (DQI) pathway, and more than four orders of magnitude conductance variation can be achieved by shifting the electrodes in a range of about 0.6 nm, which is the highest conductance range ever achieved using mechanical tuning.

Control of Raman Scattering Quantum Interference Pathways in Graphene.

Graphene is an ideal platform to study the coherence of quantum interference pathways by tuning doping or laser excitation energy. The latter produces a Raman excitation profile that provides direct insight into the lifetimes of intermediate electronic excitations and, therefore, on quantum interference, which has so far remained elusive. Here, we control the Raman scattering pathways by tuning the laser excitation energy in graphene doped up to 1.05 eV. The Raman excitation profile of the G mode indicates its position and full width at half-maximum are linearly dependent on doping. Doping-enhanced electron-electron interactions dominate the lifetimes of Raman scattering pathways and reduce Raman interference. This will provide guidance for engineering quantum pathways for doped graphene, nanotubes, and topological insulators.

Resonances and antiresonances in heat generation by spin current in a quantum dot.

We study the heat generation in a quantum dot exposed to a rotating magnetic field and coupled to a normal lead. Both electron-phonon interaction and electron-electron interaction are considered in the dot. We show the emergence of resonances and antiresonances in the heat generation, which we attribute to constructive interference and destructive interference between phonon waves emitted from opposite spin channels in the dot.

Quantum Interference between Fundamentally Different Processes Is Enabled by Shaped Input Wavefunctions.

This work presents a general framework for quantum interference between processes that can involve different fundamental particles or quasi-particles. This framework shows that shaping input wavefunctions is a versatile and powerful tool for producing and controlling quantum interference between distinguishable pathways, beyond previously explored quantum interference between indistinguishable pathways. Two examples of quantum interference enabled by shaping in interactions between free electrons, bound electrons, and photons are presented: i) the vanishing of the zero-loss peak by destructive quantum interference when a shaped electron wavepacket couples to light, under conditions where the electron's zero-loss peak otherwise dominates; ii) quantum interference between free electron and atomic (bound electron) spontaneous emission processes, which can be significant even when the free electron and atom are far apart, breaking the common notion that a free electron and an atom must be close by to significantly affect each other's processes. Conclusions show that emerging quantum wave-shaping techniques unlock the door to greater versatility in light-matter interactions and other quantum processes in general.

Intermixing-Driven Surface and Bulk Ferromagnetism in the Quantum Anomalous Hall Candidate MnBi6 Te10.

The recent realizations of the quantum anomalous Hall effect (QAHE) in MnBi2 Te4 and MnBi4 Te7 benchmark the (MnBi2 Te4 )(Bi2 Te3 )n family as a promising hotbed for further QAHE improvements. The family owes its potential to its ferromagnetically (FM) ordered MnBi2 Te4 septuple layers (SLs). However, the QAHE realization is complicated in MnBi2 Te4 and MnBi4 Te7 due to the substantial antiferromagnetic (AFM) coupling between the SLs. An FM state, advantageous for the QAHE, can be stabilized by interlacing the SLs with an increasing number n of Bi2 Te3 quintuple layers (QLs). However, the mechanisms driving the FM state and the number of necessary QLs are not understood, and the surface magnetism remains obscure. Here, robust FM properties in MnBi6 Te10 (n = 2) with Tc ≈ 12 K are demonstrated and their origin is established in the Mn/Bi intermixing phenomenon by a combined experimental and theoretical study. The measurements reveal a magnetically intact surface with a large magnetic moment, and with FM properties similar to the bulk. This investigation thus consolidates the MnBi6 Te10 system as perspective for the QAHE at elevated temperatures.

Scaling of quantum interference from single molecules to molecular cages and their monolayers.

The discovery of quantum interference (QI) is widely considered as an important advance in molecular electronics since it provides unique opportunities for achieving single-molecule devices with unprecedented performance. Although some pioneering studies suggested the presence of spin qubit coherence and QI in collective systems such as thin films, it remains unclear whether the QI can be transferred step-by-step from single molecules to different length scales, which hinders the application of QI in fabricating active molecular devices. Here, we found that QI can be transferred from a single molecule to their assemblies. We synthesized and investigated the charge transport through the molecular cages using 1,3-dipyridylbenzene (DPB) as a ligand block with a destructive quantum interference (DQI) effect and 2,5-dipyridylfuran (DPF) as a control building block with a constructive quantum interference (CQI) effect using both single-molecule break junction and large area junction techniques. Combined experiments and calculations revealed that both DQI and CQI had been transferred from the ligand blocks to the molecular cages and the monolayer thin film of the cages. Our work introduced QI effects from a ligand to the molecular cage comprising 732 atoms and even their monolayers, suggesting that the quantum interference could be scaled up within the phase-coherent distance.