Ultra-high-sensitive plasmonic sensor based on asymmetric hexagonal nano-ring resonator for cancer detection.

A highly sensitive sensor based on two metal-insulator-metal waveguides coupled to an asymmetric hexagonal nano-ring resonator detecting cancerous cells is proposed. This novel design is utilized to facilitate the sensing of human cells. The sensing mechanism of the presented optical structure can act as a refractive index measurement in biological, chemical, biomedical diagnosis, and bacteria detection, which leads to achieving high sensitivity in the structure. The main goal is to achieve the highest sensitivity concerning the optimum design. As a result, the sensitivity of the designed topology reaches a maximum value of about 1800 nm/RIU (nm/refractive index unit) by controlling the angle of the resonator. It is evident that the sensitivity parameter is improved, and the reason for the increase in sensitivity is due to the asymmetry of the resonator, which has an 81 % increase in sensitivity compared to the symmetrical resonator, especially for blood cancer cells. The maximum quality factor obtains 131.65 with a FOM of 90.4 (RIU-1). The sensing performance of this proposed structure is numerically investigated using the finite difference time domain (FDTD) method with the perfectly matched layer (PML). Accordingly, the suggested high sensitivity sensor makes this structure a promising therapeutic candidate for sensing applications that can be used in on-chip optical devices to produce highly complex integrated circuits.

Design, Fabrication, and Dynamic Analysis of a MEMS Ring Resonator Supported by Twin Circular Curve Beams.

In this paper, we present a compressive study on the design and development of a MEMS ring resonator and its dynamic behavior under electrostatic force when supported by twin circular curve beams. Finite element analysis (FEA)-based modeling techniques are used to simulate and refine the resonator geometry and transduction. In proper FEA or analytical modeling, the explicit description and accurate values of the effective mass and stiffness of the resonator structure are needed. Therefore, here we outlined an analytical model approach to calculate those values using the first principles of kinetic and potential energy analyses. The natural frequencies of the structure were then calculated using those parameters and compared with those that were simulated using the FEA tool ANSYS. Dynamic analysis was performed to calculate the pull-in voltage, shift of resonance frequency, and harmonic analyses of the ring to understand how the ring resonator is affected by the applied voltage. Additional analysis was performed for different orientations of silicon and assessing the frequency response and frequency shifts. The prototype was fabricated using the standard silicon-on-insulator (SOI)-based MEMS fabrication process and the experimental results for resonances showed good agreement with the developed model approach. The model approach presented in this paper can be used to provide valuable insights for the optimization of MEMS resonators for various operating conditions.

3D Bulk Metamaterials with Engineered Optical Dispersion at Terahertz Frequencies Utilizing Amorphous Multilayered Split-Ring Resonators.

A 3D bulk metamaterial (MM) containing amorphous multilayered split-ring resonators is proposed, fabricated, and evaluated. Experimentally, the effective refractive index is engineered via the 3D bulk MM, with a contrast of 0.118 across the frequency span from 0.315 to 0.366 THz and the index changing at a slope of 2.314 per THz within this frequency range. Additionally, the 3D bulk MM exhibits optical isotropy with respect to polarization. Moreover, the peak transmission and optical dispersion are tailored by adjusting the density of the split-ring resonators. Compared to reported conventional approaches for constructing bulk MMs, this approach offers advantages in terms of the potential for large-scale manufacturing, the ability to adopt any shape, optical isotropy, and rapid optical dispersion. These features hold promise for dispersive optical devices operating at THz frequencies, such as high-dispersive prisms for high-resolution spectroscopy.

Controllable Pseudospin Topological Add-Drop Filter Based on Magnetic-Optical Photonic Crystals.

We propose a controllable topological add-drop filter based on magnetic-optical photonic crystals. This add-drop filter is composed of two straight waveguides and a hexagonal photonic crystal ring resonator. The waveguide and ring resonator are constructed by three different honeycomb magnetic-optical photonic crystals. The expanded lattice is applied with an external magnetic field so that it breaks time-reversal symmetry and the analogous quantum spin Hall effect simultaneously. While the standard one and the compressed one are not magnetized and trivial, the straight waveguide supports pseudospin-down (or pseudospin-up) one-way states when the expanded lattice is applied with an external magnetic field of +H (or -H). The ring resonator possesses multiple resonant modes which can be divided into travelling modes and standing modes. By using the travelling modes, we have demonstrated the function of the add-drop filter and realized the output port control by changing the direction of the magnetic field. Moreover, a large tunable power ratio from near 0 to 52.6 is achieved by adjusting the strength of the external magnetic field. The structure has strong robustness against defects due to the topological protection property. These results have potential in wavelength division multiplexing systems and integrated topological optical devices.

Non-Destructive Sensor for Glucose Solution Concentration Detection Using Electromagnetic Technology.

In this paper, a sensor using a complementary split ring resonator (CSRR) is proposed for non-destructive testing of blood glucose. By depicting the complementary split ring structure on the ground, the electromagnetic field strength between the split rings can be enhanced effectively. The structure size of the sensor by CSRR is determined by simulation, so that the insertion loss curve of the device has a resonance point at the frequency of 3.419 GHz. With a special holder created by three-dimensional (3D) printing technology, the test platform was established when the concentration of the solution varied from 0 mg/mL to 20 mg/mL. The experimental results indicate that there is an obvious linear relationship between the insertion loss S21 and the glucose concentration at the resonant frequency. Similarly, the measured real part and imaginary part of the S21 both vary with glucose concentration linearly. Based on the above experimental results, the feasibility of the sensor using a CSRR proposed in this paper for non-destructive detection of blood glucose is preliminarily verified.

Racetrack Ring Resonator-Based on Hybrid Plasmonic Waveguide for Refractive Index Sensing.

In this study, a comprehensive numerical analysis is conducted on a hybrid plasmonic waveguide (HPWG)-based racetrack ring resonator (RTRR) structure, tailored specifically for refractive index sensing applications. The sensor design optimization yields remarkable results, achieving a sensitivity of 275.7 nm/RIU. Subsequently, the boundaries of sensor performance are pushed even further by integrating a subwavelength grating (SWG) structure into the racetrack configuration, thereby augmenting the light-matter interaction. Of particular note is the pivotal role played by the length of the SWG segment in enhancing device sensitivity. It is observed that a significant sensitivity enhancement can be obtained, with values escalating from 377.1 nm/RIU to 477.7 nm/RIU as the SWG segment length increases from 5 µm to 10 µm, respectively. This investigation underscores the immense potential of HPWG in tandem with SWG for notably enhancing the sensitivity of photonic sensors. These findings not only advance the understanding of these structures but also pave the way for the development of highly efficient sensing devices with unprecedented performance capabilities.

Trenched microwave resonator integrated with porous PDMS for detection and classification of VOCs with enhanced performance.

Microwave resonators combined with polymer absorption layers are widely used in volatile organic compound (VOC) detection based on their variable resonant frequencies. However, the response time is limited due to the polymer's slow volumetric absorption of VOC molecules. By constructing a porous structure in Polydimethylsiloxane (PDMS), resulting in reduced the response time to as short as 71.1%. To mitigate the sensitivity decline caused by the porous PDMS, a trenched-substrate complementary split-ring resonator (CSRR) is proposed for enhancing the interaction between the electromagnetic fields (EMFs) and the porous PDMS with VOCs. The removal of the substrate beneath CSRR's sensing region enhances the effective EMF, increasing frequency and amplitude sensitivities up to 175.5% and 137.8%, respectively. Responses to four common VOCs by the sensor show a maximum sensitivity of 217 Hz/ppm and a minimum limit of detection of 295 ppm. Additionally, resonant parameters and extracted lumped parameters are utilized to establish two decision-tree-based VOC classification models, achieving high accuracies of 98.71% and 99.59%, respectively. And the latter one fully utilizing responses throughout the swept band, proves superior in identifying similar substances. This sensor technology helps promote the sensitive detection and accurate classification of diverse VOCs.

A CMOS-integrated terahertz near-field sensor based on an ultra-strongly coupled meta-atom.

Recently, plasmonic-based sensors operating in the terahertz frequency range have emerged as perspective tools for rapid and efficient label-free biosensing applications. In this work, we present a fully electronic approach allowing us to achieve state-of-the-art sensitivity by utilizing a near-field-coupled electronic sensor. We demonstrate that the proposed concept enables the efficient implementation and probing of a so-called ultra-strongly coupled sub-wavelength meta-atom as well as a single resonant circuit, allowing to limit the volume of material under test down to a few picoliter range. The sensor has been monolithically integrated into a cost-efficient silicon-based CMOS technology. Our findings are supported by both numerical and analytical models and validated through experiments. They lay the groundwork for near-future developments, outlining the perspectives for a terahertz microfluidic lab-on-chip dielectric spectroscopy sensor.

A Multiplex "Disposable Photonics" Biosensor Platform and Its Application to Antibody Profiling in Upper Respiratory Disease.

Photonic technologies promise to deliver quantitative, multiplex, and inexpensive medical diagnostic platforms by leveraging the highly scalable processes developed for the fabrication of semiconductor microchips. However, in practice, the affordability of these platforms is limited by complex and expensive sample handling and optical alignment. We previously reported the development of a disposable photonic assay that incorporates inexpensive plastic micropillar microfluidic cards for sample delivery. That system as developed was limited to singleplex assays due to its optical configuration. To enable multiplexing, we report a new approach addressing multiplex light I/O, in which the outputs of individual grating couplers on a photonic chip are mapped to fibers in a fiber bundle. As demonstrated in the context of detecting antibody responses to influenza and SARS-CoV-2 antigens in human serum and saliva, this enables multiplexing in an inexpensive, disposable, and compact format.

Two-Layer Inkjet-Printed Microwave Split-Ring Resonators for Detecting Analyte Binding to the Gold Surface.

This work focuses on demonstrating the working principle of inkjet-printed Au nanoparticle (NP) two-layer Gigahertz (2.6 GHz) microwave split-ring resonators (SRRs) as a novel platform for the detection of analytes on flexible substrates. In contrast to the standard fabrication of split-ring resonator biosensors using printed circuit board technology, which results in a seven-layer system, the resonators in this work were fabricated using a two-layer system. A ground plane is embedded in the SRR measurement setup. In this method, a microwave electromagnetic wave is coupled into the Au SRR via an inkjet-printed Cu-NP stripline that is photonically sintered. This coupling mechanism facilitates the detection of analytes by inducing resonance shifts in the SRR. In this study, the functionality of the printed sensors was demonstrated using two different Au functionalization processes, firstly, with HS-PEG7500-COOH, and, secondly, with protein G with an N-terminal cysteine residue. The sensing capabilities of the printed structures are shown by the attachment of biomolecules to the SRR and the measurement of the resulting resonance shift. The experiments show a clear shift of the resonance frequency in the range of 20-30 MHz for both approaches. These results demonstrate the functionality of the simplified printed two-layer microwave split-ring resonator for use as a biosensor.

Highly Sensitive Microwave Sensors Based on Open Complementary Square Split-Ring Resonator for Sensing Liquid Materials.

This paper presents high-sensitivity sensors based on an open complementary square split-ring resonator and a modified open complementary split-ring resonator operating at 4.5 GHz and 3.4 GHz, respectively. The sensors are designed for the detection of multiple liquid materials, including distilled water, methanol, and ethanol. The liquid under test is filled in a glass container loaded using a pipette. Compared to the conventional OCSSRR, the modified OCSSRR with multiple rings exhibits a higher frequency shift of 1200 MHz, 1270 MHz, and 1520 MHz for ethanol, methanol, and distilled water, respectively. The modified sensor also demonstrates a high sensitivity of 308 MHz/RIU for ethanol concentration which is the highest among the existing microwave sensors. The sensors in this manuscript are suitable for multiple liquid-material-sensing applications.

A Microwave Differential Dielectric Sensor Based on Mode Splitting of Coupled Resonators.

This study explores the viability of using the avoided mode crossing phenomenon in the microwave regime to design microwave differential sensors. While the design concept can be applied to any type of planar electrically small resonators, here, it is implemented on split-ring resonators (SRRs). We use two coupled synchronous SRRs loaded onto a two-port microstrip line system to demonstrate the avoided mode crossing by varying the distance between the split of the resonators to control the coupling strength. As the coupling becomes stronger, the split in the resonance frequencies of the system increases. Alternatively, by controlling the strength of the coupling by materials under test (MUTs), we utilize the system as a microwave differential sensor. First, the avoided mode crossing is theoretically investigated using the classical microwave coupled resonator techniques. Then, the system is designed and simulated using a 3D full-wave numerical simulation. To validate the concept, a two-port microstrip line, which is magnetically coupled to two synchronous SRRs, is utilized as a sensor, where the inter-resonator coupling is chosen to be electric coupling controlled by the dielectric constant of MUTs. For the experimental validation, the sensor was fabricated using printed circuit board technology. Two solid slabs with dielectric constants of 2.33 and 9.2 were employed to demonstrate the potential of the system as a novel differential microwave sensor.

Numerical analysis of a highly sensitive SOI MRR refractive index sensor with performance enhancement using graphene and gold.

This study proposes a simulation-based design for a Silicon-On-Insulator (SOI) ring resonator with a Figure of Merit (FOM) of 56.15 and a high sensitivity of up to 730 nm/RIU. The Finite-Difference Time-Domain (FDTD) technique was used to assess and evaluate the design quantitatively. Our design demonstrates higher sensitivity compared to many recent studies conducted on SOI-based sensors. The device structure follows a conventional ring resonator arrangement with a single waveguide, incorporating a 2D graphene layer on top of the SiO2 wafer and a gold nano-disc positioned at the center of the ring. Our findings highlight the device's susceptibility to refractive index variations, making it a desirable choice for various sensing applications. We have investigated the sensor's capabilities for sensing different concentrations of milkmilk. Graphene and gold materials enhance the device's response to light and provide comparatively higher sensitivity. The suggested design can serve as a blueprint for device fabrication, considering the practicality of implementing an SOI-based device using standard techniques for silicon processing.

Development of double-layer metamaterial with high effective medium ratio values for S- and C-band applications.

This study introduces a compact double negative metamaterial (DNM) composed of three split rings connected slab resonator (TSRCSR) based double-layer design with a high 13.9 EMR (effective medium ratio) value. A double-layer patch is introduced to achieve the novel double negative properties, including negative behaviours of effective medium parameters, including refractive index, permittivity, and permeability with a high effective medium ratio for the miniaturised size of the introduced unconventional material that is highly suitable for microwave S and C band covering applications. The popular low-loss Rogers RT5880 (thickness 1.575 mm) substrate and copper resonator materials are utilized to develop the metamaterial unit cell that offers triple resonance between frequencies from 1 to 8 GHz. Therefore, the proposed metamaterial exhibits resonance peaks at 2.75, 5.2, and 6.3 GHz, suitable for radar, communication satellite, and long-distance telecommunication applications, respectively. The commercially available simulator known as Computer Simulation Technology (CST) is adopted to develop and simulate the 8 × 8 mm2 metamaterial design. The simulation results of the introduced TSRCSR design structure were verified by adopting the Ansys High-Frequency Structure Simulator (HFSS). Furthermore, it was then proved with the help of equivalent circuit model findings gained from the Advanced Design Structure (ADS) software. On the other hand, the analytical results were further validated by measuring the TSRCSR design utilizing a Vector Network Analyzer (VNA). These analyses become one of the novelties of this work, where the compact TSRCSR metamaterial successfully gained small discrepancies in transmission coefficient values when compared to both analytical and measurement results. The proposed metamaterial is highly suggested for communication devices for its extensive effective characteristics and compactness.

Whispering-Gallery Mode Micro-Ring Resonator Integrated with a Single-Core Fiber Tip for Refractive Index Sensing.

A micro-ring resonator structure was fabricated via the two-photon polymerization technique directly on a single-mode fiber tip and tested for refractive index sensing application. The micro-ring structure was used to excite whispering-gallery modes, and observations of the changes in the resonance spectrum introduced by changes in the refractive index of the environment served as the sensing principle. The proposed structure has the advantages of a very simple design, allowing for measurements in reflection mode, relatively easy and fast fabrication and integration with a single tip of a standard single-mode fiber, which allowed for quick and convenient measurements in the optical setup. The performance of the structure was characterized, and the resonant spectrum giving high potential for refractive index sensing was measured. Future perspectives of the research are addressed.

Correlation of Transmission Properties with Glucose Concentration in a Graphene-Based Microwave Resonator.

Carbon-based materials, such as graphene, exhibit interesting physical properties and have been recently investigated in sensing applications. In this paper, a novel technique for glucose concentration correlation with the resonant frequency of a microwave resonator is performed. The resonator exploits the variation of the electrical properties of graphene at radio frequency (RF). The described approach is based on the variation in transmission coefficient resonating frequency of a microstrip ring resonator modified with a graphene film. The graphene film is doctor-bladed on the ring resonator and functionalised in order to detect glucose. When a drop with a given concentration is deposited on the graphene film, the resonance peak is shifted. The graphene film is modelled with a lumped element analysis. Several prototypes are realised on Rogers Kappa substrate and their transmission coefficient measured for different concentrations of glucose. Results show a good correlation between the frequency shift and the concentration applied on the film.

A Miniature Eight-Port Antenna Array Based on Split-Ring Resonators for 5G Sub-6 GHz Handset Applications.

In this article, a miniature eight-port multiple-input multiple-output (MIMO) antenna array is proposed for fifth-generation (5G) sub-6 GHz handset applications. The individual antenna element comprises a radiator shaped like the Chinese character "" (phonetically represented as "Wang") and three split-ring resonators (SRR) on the metal frame. The size of the individual antenna element is only 6.8 × 7 × 1 mm3 (47.6 mm3). The proposed antenna element has a -10 dB impedance bandwidth of 1.7 GHz (from 3.3 GHz to 5 GHz) that can cover 5G New Radio (NR) sub-6 GHz bands N77 (3.3-4.2 GHz), N78 (3.3-3.8 GHz), and N79 (4.4-5 GHz). The evolution design, the current distribution, the effects of single-handed holding, and the analysis of the parameters are deduced to study the approach used to design the featured antenna. The measured total efficiencies are from 40% to 80%, the isolation is better than 12 dB, the calculated envelope correlation coefficient (ECC) is less than 0.12, and the calculated channel capacity (CC) ranges from 35 to 38 bps/Hz. The presented antenna array is a good alternative to 5G mobile handsets with wideband operation, a metal frame, and minimized spacing.

Theoretical and experimental study on the detection limit of the micro-ring resonator based ultrasound point detectors.

Combining the diffusive laser excitation and the photoacoustic signals detection, photoacoustic computed tomography (PACT) is uniquely suited for deep tissue imaging. A diffraction-limited ultrasound point detector is highly desirable for maximizing the spatial resolution and the field-of-view of the reconstructed volumetric images. Among all the available ultrasound detectors, micro-ring resonator (MRR) based ultrasound detectors offer the lowest area-normalized limit of detection (nLOD) in a miniature form-factor, making it an ideal candidate as an ultrasound point detector. However, despite their wide adoption for photoacoustic imaging, the underlying signal transduction process has not been systematically studied yet. Here we report a comprehensive theoretical model capturing the transduction of incident acoustic signals into digital data, and the associated noise propagation process, using experimentally calibrated key process parameters. The theoretical model quantifies the signal-to-noise ratio (SNR) and the nLOD under the influence of the key process variables, including the quality factor (Q-factor) of the MRR and the driving wavelength. While asserting the need for higher Q-factors, the theoretical model further quantifies the optimal driving wavelength for optimizing the nLOD. Given the MRR with a Q-factor of 1 × 105, the theoretical model predicts an optimal SNR of 30.1 dB and a corresponding nLOD of 3.75 × 10-2 mPa mm2/Hz1/2, which are in good agreement with the experimental measurements of 31.0 dB and 3.39 × 10-2 mPa mm2/Hz1/2, respectively. The reported theoretical model can be used in guiding the optimization of MRR-based ultrasonic detectors and PA experimental conditions, in attaining higher imaging resolution and contrast. The optimized operating condition has been further validated by performing PACT imaging of a human hair phantom.

Electrical Detection of Ultrastrong Coherent Interaction between Terahertz Fields and Electrons Using Quantum Point Contacts.

Light-matter interaction in the ultrastrong coupling regime is attracting considerable attention owing to its applications to coherent control of material properties by a vacuum fluctuation field. However, electrical access to such an ultrastrongly coupled system is very challenging. In this work, we have fabricated a gate-defined quantum point contact (QPC) near the gap of a terahertz (THz) split-ring resonator (SRR) fabricated on a GaAs two-dimensional (2D) electron system. By illuminating the system with external THz radiation, the QPC shows a photocurrent spectrum which exhibits significant anticrossing that arises from coupling between the cyclotron resonance of the 2D electrons and the SRR. The observed photocurrent signal can be explained by energy-selective transmission/reflection of the quantum Hall edge channels at the QPC. Furthermore, at the same gate voltage and magnetic field conditions under which the anticrossing signal was observed, the QPC exhibits anomalous conductance modulation even in the dark environment.

Design and Demonstration of a Microelectromechanical System Single-Ring Resonator with Inner Ring-Shaped Spring Supports for Inertial Sensors.

This paper presents a novel single-ring resonator design and experimentally demonstrates its dynamic behavior. The proposed ring resonator design is simple and has a solid anchor at its center connected to an outside ring via inner ring-shaped springs. The mode shapes and frequency of the ring resonator were determined numerically and compared with analytical approaches, and the minimum split frequency was observed for the n = 3 mode of vibration. Numerical and analytical methods were used to determine the resonance frequencies, pull-in voltage, resonance frequency shift and harmonic response of the ring resonator for different silicon orientations. The split frequency in the n = 3 mode of vibration increases by the applied DC bias voltage almost by the same amount for all types of silicon. When an AC voltage with a 180-degree phase is applied to two opposite electrodes, the ring has two resonance frequencies in mode n = 2, and when the AC voltage applied to two opposite electrodes is in the same phase, the ring has one resonance frequency regardless of the crystal orientation of silicon. Prototypes were fabricated using a double silicon-on-insulator-based wafer fabrication technique and were tested to verify the resonator performance.