RESUMO
BACKGROUND/OBJECTIVES: Pediatric vulvar disease has not been widely explored in the medical literature. Few studies focus on vulvar disease in skin of color. The vulvar disease can be distressing for young patients given the sensitive location, and providers may lack experience in diagnosing and managing vulvar dermatoses. We sought to characterize the conditions seen, diagnostic challenges encountered, and the racial and ethnic factors associated with vulvar diseases in our multidisciplinary pediatric dermatology-gynecology vulvar clinic at Children's National. METHODS: Medical records of 220 patients who presented to our multidisciplinary pediatric dermatology-gynecology clinic were reviewed retrospectively. RESULTS: Lichen sclerosus (LS) (36%, n = 80), inflammatory vulvitis (11%, n = 23), and vitiligo (9%, n = 19) were the three most frequent conditions observed. These conditions were often misdiagnosed as one another. There was a mean delay in diagnosis after symptom onset in LS patients of 16.43 months. CONCLUSIONS: LS, inflammatory vulvitis, and vitiligo are common vulvar diseases among pediatric patients. Accurate diagnosis is important because LS must be treated aggressively to prevent sequelae. Further studies are warranted to help differentiate LS and vitiligo with consideration of skin tone.
Assuntos
Dermatologia , Líquen Escleroso e Atrófico , Vitiligo , Doenças da Vulva , Líquen Escleroso Vulvar , Vulvite , Feminino , Criança , Humanos , Estudos Retrospectivos , Vitiligo/diagnóstico , Líquen Escleroso e Atrófico/diagnóstico , Doenças da Vulva/diagnóstico , Doenças da Vulva/terapia , Doenças da Vulva/complicações , Vulvite/complicações , Líquen Escleroso Vulvar/complicaçõesRESUMO
Fibroma mole, ou pólipo fibroepitelial, é uma lesão de proporções geralmente reduzidas, de cor hiperpigmentada ou igual à da pele, localizando-se frequentemente na face, pescoço, tronco e regiões intertriginosas. É um tumor classificado como benigno e pode acometer tanto homens quanto mulheres em idade reprodutiva e depois da quarta década de vida. Ocorre principalmente em obesos, diabéticos e durante a gestação. Com menor frequência, podem alcançar dimensões que excedem 5 cm. Seu crescimento pode ser lento ou rápido e comumente são assintomáticos, mas podem promover sangramentos por conta de ulcerações decorrentes de traumas repetidos. Apresentamos neste relato um fibroma mole, gigante, de localização vulvar, com 11 cm de comprimento, 11 cm de largura e 5 cm de espessura, pesando 500 g.
Giant soft vulvar fibroma is a fibroepithelial polyp lesion with generally reduced proportions, with a hyperpigmented color or similar to that of the skin, frequently located on the face, neck, trunk and intertriginous regions. It is a tumor classified as benign, can affect both men and women, of reproductive age and after the fourth decade, mainly obese, diabetic and during pregnancy. However, less frequently, they can reach dimensions that exceed 5 cm, may have a slow or accelerated evolution. They are commonly asymptomatic, but bleeding may be present due to ulcerations resulting from repeated trauma. In the current study, we describe a giant soft fibroma with a vulvar location measuring 11 cm in length, 11 cm in width, 5 cm in thickness and weighing 500 grams.
Assuntos
Humanos , Feminino , Adulto , Fibroma/cirurgia , Fibroma/etiologia , Procedimentos Cirúrgicos em Ginecologia , Vulva/patologia , Doenças da Vulva/complicações , Neoplasias Vulvares , Ferimentos e Lesões/complicações , Relatos de Casos , Células Estromais/patologia , Neoplasias Fibroepiteliais/reabilitaçãoRESUMO
OBJECTIVE: The aim of the study is to determine intraoperative and postoperative surgical outcomes for the treatment of vulvovaginal agglutination secondary to lichen planus (LP) following a standard protocol using intraoperative dilator placement and postoperative intravaginal steroid use. MATERIALS AND METHODS: This was a retrospective chart review of patients who underwent surgical management of vulvovaginal agglutination due to LP following a protocol that included surgical lysis of vulvovaginal adhesions, intraoperative dilator placement and removal 48 hours later, and high-potency intravaginal corticosteroid and regular dilator use thereafter. Demographic and clinical data were abstracted from the medical record and analyzed using descriptive statistics. RESULTS: Thirty-four patients, with mean age 51.2 ± 11 years and body mass index 32.8 ± 8.5 kg/m 2 , underwent lysis of vulvovaginal adhesions between 1999 and 2021 with 8 different surgeons at a single institution. The mean preoperative, immediate postoperative, and 6-week postoperative vaginal lengths were 2.8 ± 1.8 cm ( n = 18), 8.0 ± 1.9 cm ( n = 21), and 7.9 ± 2.2 cm ( n = 16), respectively. The mean estimated blood loss intraoperatively was 16 ± 15 mL. No patients had a documented surgical site infection or reoperation within 30 days after surgery. Of patients who had it documented ( n = 26), 70% (18/26) reported postoperative sexual activity. Where documented, 100% (18/18) reported preoperative dyspareunia, while 17% (3/18) did postoperatively. Six percent (2/34) had recurrent severe agglutination and 3% (1/34) underwent reoperation. CONCLUSIONS: Lysis of vulvovaginal adhesions, intraoperative dilator placement, and postoperative intravaginal corticosteroids with dilator use is a safe and effective treatment option to restore vaginal length for those with vulvovaginal LP.
Assuntos
Líquen Plano , Doenças da Vulva , Feminino , Humanos , Adulto , Pessoa de Meia-Idade , Doenças da Vulva/cirurgia , Doenças da Vulva/complicações , Estudos Retrospectivos , Líquen Plano/tratamento farmacológico , Líquen Plano/cirurgia , Resultado do Tratamento , AglutinaçãoRESUMO
BACKGROUND: Nonsexually acquired genital ulcers have been described among girls who are prepubertal after various viral illnesses due to mucosal inflammation from an immunologic response. Until recently, nonsexually acquired genital ulcers have only been associated with viral infections. CASE: We present a case of an adolescent girl developing nonsexually acquired genital ulcers after both her first and second coronavirus disease 2019 (COVID-19) vaccine doses. Her course followed an expected timeline for severity and resolution of ulcers. CONCLUSIONS: Aphthous ulcers may arise from inflammatory effects of COVID-19 vaccination. Clinical monitoring after COVID-19 vaccination from all formulations should include assessment for nonsexually acquired genital ulcers if vaginal pain is reported.
Assuntos
Vacinas contra COVID-19 , COVID-19 , Estomatite Aftosa , Viroses , Doenças da Vulva , Adolescente , Feminino , Humanos , COVID-19/prevenção & controle , Vacinas contra COVID-19/efeitos adversos , Estomatite Aftosa/complicações , Úlcera/diagnóstico , Úlcera/etiologia , Vacinação , Viroses/complicações , Doenças da Vulva/complicaçõesRESUMO
Lipschutz ulcers, or non-sexually acquired genital ulcers, typically occur in older children and young adults. A diagnosis of Lipschutz ulcers can only be made after excluding common infectious and non-infectious causes of mucosal ulcers. Herein, we present the case of a 4-month-old girl with painful ulceration of the labia consistent with Lipschutz ulcers.
Assuntos
Úlcera , Doenças da Vulva , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Dor/etiologia , Úlcera/complicações , Úlcera/diagnóstico , Doenças da Vulva/complicações , Doenças da Vulva/diagnósticoRESUMO
BACKGROUND: In this case report, we presented a rare case of maternal death with massive vulvar edema and Covid-19 diagnosis. CASE PRESENTATION: The case was a 20-year-old woman who was referred to with pain and massive vulvar edema by passing 7 days from her labor. The laboratory tests showed leukocytosis, lymphopenia, and elevated C-reactive protein levels. The high-resolution computed tomography was in favor of Covid-19 changes. Finally, she died because of respiratory distress, ON the 8th day postpartum. CONCLUSION: Given the increasing prevalence of Covid-19, it is important and vital to be aware of its potential complications and then to try prevent and manage them, especially during high-risk periods such as pregnancy and postpartum.
Assuntos
COVID-19/complicações , Edema/complicações , Edema/diagnóstico por imagem , Morte Materna , Período Pós-Parto , SARS-CoV-2/genética , Doenças da Vulva/complicações , Doenças da Vulva/diagnóstico por imagem , COVID-19/sangue , COVID-19/virologia , Teste para COVID-19/métodos , Evolução Fatal , Feminino , Humanos , Linfopenia , Gravidez , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Tomografia Computadorizada por Raios X/métodos , Adulto JovemRESUMO
Vulvar epidermolytic hyperkeratosis is a benign entity that mimics other malignant and inflammatory vulvar dermatoses clinically and histologically requiring careful clinical pathologic correlation for diagnosis.
Assuntos
Hiperceratose Epidermolítica/patologia , Doenças da Vulva/patologia , Corticosteroides/uso terapêutico , Idoso , Inibidores de Calcineurina/uso terapêutico , Doença Crônica , Diagnóstico Diferencial , Feminino , Humanos , Hiperceratose Epidermolítica/complicações , Prurido/tratamento farmacológico , Prurido/etiologia , Doenças da Vulva/complicações , Neoplasias Vulvares/diagnósticoAssuntos
Adenocarcinoma de Células Claras/patologia , Episiotomia , Períneo , Neoplasias Vulvares/patologia , Adenocarcinoma de Células Claras/complicações , Adenocarcinoma de Células Claras/metabolismo , Adenocarcinoma de Células Claras/cirurgia , Ácido Aspártico Endopeptidases/metabolismo , Endometriose/complicações , Feminino , Humanos , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Fator de Transcrição PAX8/metabolismo , Doenças da Vulva/complicações , Neoplasias Vulvares/complicações , Neoplasias Vulvares/metabolismo , Neoplasias Vulvares/cirurgiaRESUMO
We present a case of 26-year female who presented with acute urinary retention and vulvar mass. She denies any urinary complaints in the past except for occasional straining for voiding. Imaging revealed a prolapsed ureterocele, it was successfully managed with incision and excising a flap of ureterocele due to the risk of postoperative protrusion of the redundant ureterocele. On follow-up at 6 months she was voiding well without any complaints.
Assuntos
Ureterocele/diagnóstico por imagem , Ureterocele/cirurgia , Doenças da Vulva/complicações , Doenças da Vulva/cirurgia , Adulto , Feminino , Humanos , Imageamento por Ressonância Magnética , Prolapso , Retalhos Cirúrgicos , Retenção Urinária/complicações , Doenças da Vulva/diagnóstico por imagemRESUMO
RATIONALE: Voiding difficulty is more common in males, although it is not uncommon in females. Female voiding difficulty can be caused by iatrogenic, anatomic, and neurogenic factors, and specifically urethra stricture, impaired detrusor contractility, primary bladder neck obstruction, and detrusor-external sphincter dyssynergia. Labial adhesion is a rare cause of female voiding difficulty.The incidence of labial fusion has been reported to be 0.6% to 1.4% in children; however, the incidence in the elderly has yet to be fully elucidated. PATIENT CONCERNS: We present the case of a postmenopausal and sexually inactive 76-year-old female patient who had nearly total vaginal and urethral occlusion due to labial adhesion. She had no underlying diseases and came to our clinic with a 10-month history of voiding difficulty, postmicturition dribbling, and involuntary urinary leakage when getting up. DIAGNOSIS: A genital examination revealed nearly total fusion of the labia minor with only a 3-mm pinhole opening at the posterior end. INTERVENTIONS: Treatment included surgical separation, the local application of estrogen cream, and self-dilatation. She also received an antimuscarinic agent to treat overactive bladder secondary to bladder outlet obstruction which was caused by labial adhesion. OUTCOMES: No surgical complications occurred. Moreover, no labial adhesion or voiding dysfunction was found immediately after the surgery or after 6 months of follow-up. LESSONS SUBSECTIONS: Genital examinations are a basic but very important noninvasive skill for physicians. This case report highlights that genital examinations should be a priority for patients with gynecological or urological symptoms.
Assuntos
Estrogênios/administração & dosagem , Obstrução do Colo da Bexiga Urinária , Bexiga Urinária Hiperativa , Procedimentos Cirúrgicos Urogenitais/métodos , Doenças da Vulva , Idoso , Feminino , Humanos , Antagonistas Muscarínicos/uso terapêutico , Pós-Menopausa , Resultado do Tratamento , Uretra/patologia , Uretra/fisiopatologia , Obstrução do Colo da Bexiga Urinária/etiologia , Obstrução do Colo da Bexiga Urinária/fisiopatologia , Obstrução do Colo da Bexiga Urinária/cirurgia , Bexiga Urinária Hiperativa/tratamento farmacológico , Bexiga Urinária Hiperativa/etiologia , Micção , Cremes, Espumas e Géis Vaginais/administração & dosagem , Doenças da Vulva/complicações , Doenças da Vulva/diagnóstico , Doenças da Vulva/fisiopatologia , Doenças da Vulva/cirurgiaRESUMO
OBJECTIVE: Breastfeeding-related hypoestrogenic state has been reported as a possible risk factor for postpartum dyspareunia. This study aimed to evaluate the prevalence and characteristics of postpartum vulvovaginal atrophy according to 3 different diagnostic methods and to estimate its association with postpartum dyspareunia and daily vulvovaginal symptoms. METHODS: This is a prospective cohort study of puerperal women attending a routine postpartum checkup. Participants completed a questionnaire and underwent a gynecological examination. Atrophy was diagnosed separately according to gynecologist impression, vaginal pH measurement (≥5.1), and cytologic vaginal maturation index. Patients were followed up with a telephone survey 2-3 months later, inquiring about symptoms possibly associated with atrophy. RESULTS: Of 117 participants, vaginal atrophy was diagnosed in 48% by gynecological examination, 62% by a pH level of 5.1 or greater, and 40.2% had cytological atrophy. Of the 35.9% of women who had resumed sexual intercourse (42/117), 69% reported dyspareunia. No significant association was found between dyspareunia and atrophy parameters. There was no difference in the rates of dyspareunia among women who were exclusively breastfeeding (21/27 = 78%), partially breastfeeding (4/7 = 57%), or not breastfeeding (4/8, 50%). Atrophy was more common in breastfeeding women according to the 3 criteria (gynecological examination: 57.6% vs 16.7%, p = .006; pH: 70% vs 22%, p < .001; vaginal maturation index: 51.1% vs 0%, p < .001). Of the 117 participants, 47% reported daily vulvovaginal symptoms. Those with daily symptoms reported more dyspareunia as compared with those without daily symptoms (85% vs 52%, p = .025). CONCLUSIONS: A high prevalence of atrophy was observed in puerperal women in association with breastfeeding. There was no significant association between atrophy and dyspareunia or daily vulvovaginal symptoms.
Assuntos
Aleitamento Materno/efeitos adversos , Dispareunia/epidemiologia , Doenças Vaginais/epidemiologia , Doenças da Vulva/epidemiologia , Adulto , Atrofia/patologia , Dispareunia/complicações , Feminino , Humanos , Israel/epidemiologia , Período Pós-Parto , Prevalência , Estudos Prospectivos , Fatores de Risco , Vagina/patologia , Doenças Vaginais/complicações , Doenças Vaginais/patologia , Vulva/patologia , Doenças da Vulva/complicações , Doenças da Vulva/patologia , Adulto JovemAssuntos
Glândulas Vestibulares Maiores/microbiologia , Parametrite/microbiologia , Infecções Estreptocócicas/complicações , Doenças da Vulva/complicações , Doenças da Vulva/microbiologia , Adulto , Antibacterianos/uso terapêutico , Glândulas Vestibulares Maiores/cirurgia , Drenagem , Feminino , Humanos , Oxigenoterapia Hiperbárica , Parametrite/terapia , Infecções Estreptocócicas/tratamento farmacológico , Doenças da Vulva/cirurgiaRESUMO
OBJECTIVE: To estimate the impact of vulvovaginal atrophy (VVA) on sexual function in a clinical population of postmenopausal women. METHODS: Women 45 to 75 years old and more than 12 months after the last menstruation, who attended menopausal/gynecological centers in Italy and Spain, were included. Women with at least one VVA symptom completed the following questionnaires: Day-to-Day Impact of Vaginal Aging (DIVA), Female Sexual Function Index (FSFI), and Female Sexual Distress Scale revised (FSDS-R). A physical gynecological examination was performed to confirm the VVA diagnosis. Data were analyzed by chi-square and Student's t tests. RESULTS: In all, 2,160 evaluable women were included in the study. VVA was confirmed in 90% of the included participants. The negative impact on sexual function was significantly higher in women with than in women without confirmed VVA, as evaluated with the sexual function component (DIVA-C) of the DIVA questionnaire (Pâ=â0.013). Statistically significant differences (Pâ<â0.0005) were also detected in the scores of overall FSDS-R, the overall FSFI, and of all the FSFI subdomains (desire, arousal, lubrication, orgasm, satisfaction, and pain). CONCLUSION: For postmenopausal women with at least one VVA symptom, the presence of physician-confirmed VVA is associated with significant impaired sexual function, as shown by unadjusted analyses. Given the impact on quality of life and the prevalence of VVA, further research to improve and reduce VVA is warranted.
Assuntos
Atrofia/diagnóstico , Dispareunia/etiologia , Disfunções Sexuais Fisiológicas/etiologia , Doenças Vaginais/diagnóstico , Doenças da Vulva/diagnóstico , Idoso , Atrofia/complicações , Estudos de Casos e Controles , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Pós-Menopausa , Inquéritos e Questionários , Doenças Vaginais/complicações , Doenças da Vulva/complicaçõesRESUMO
Los tumores vulvares son un desafío diagnóstico en la práctica clínica por las múltiples etiologías subyacentes. CASO CLÍNICO: Adolescente de 13 años que presentó dos nódulos vulvares de un mes de evolución, asociados a leve dolor. Ecografía preoperatoria sospecha un quiste de inclusión epidérmica, el que se confirmó con biopsia excisional.
Vulvar tumors are a diagnostic challenge in clinical practice due to the multiple underlying etiologies. CLINICAL CASE: A 13-year-old adolescent who presented two vulvar nodules of one month of evolution, associated with mild pain. Preoperative ultrasound suspected an epidermal inclusion cyst, which was confirmed with excisional biopsy.
Assuntos
Humanos , Feminino , Adolescente , Doenças da Vulva/complicações , Doenças da Vulva/diagnóstico , Cisto Epidérmico/complicações , Cisto Epidérmico/diagnóstico , Doenças da Vulva/cirurgia , Cisto Epidérmico/cirurgiaRESUMO
Lichen sclerosus (LS) is a chronic inflammatory dermatosis commonly visualized in the anogenital region with porcelain-white atrophic patches that extend to the perianal region in a figure-of-eight configuration. While LS is known to increase lower urinary tract symptoms and incontinence in postmenopausal women, the age distribution is bimodal and literature on the LS impact in prepubertal girls remains limited. There is an association with autoimmune conditions and the pathogenesis is thought to be autoimmune with an underlying genetic predisposition. Lack of familiarity among pediatric urology providers may lead to a significant diagnostic and treatment delay, resulting irreversible genital skin changes.
Assuntos
Líquen Escleroso e Atrófico/complicações , Sintomas do Trato Urinário Inferior/etiologia , Doenças da Vulva/complicações , Criança , Feminino , Glucocorticoides/uso terapêutico , Humanos , Líquen Escleroso e Atrófico/tratamento farmacológico , Sintomas do Trato Urinário Inferior/tratamento farmacológico , Doenças da Vulva/tratamento farmacológicoAssuntos
Prurido/etiologia , Doenças da Vulva/diagnóstico , Adulto , Feminino , Humanos , Líquen Escleroso e Atrófico/complicações , Líquen Escleroso e Atrófico/diagnóstico , Pessoa de Meia-Idade , Micoses/complicações , Micoses/diagnóstico , Gravidez , Psoríase/complicações , Psoríase/diagnóstico , Doenças da Vulva/complicaçõesAssuntos
Líquen Escleroso e Atrófico/complicações , Vagina/patologia , Doenças da Vulva/complicações , Líquen Escleroso Vulvar/patologia , Idoso , Atrofia , Constrição Patológica/etiologia , Constrição Patológica/cirurgia , Dispareunia/etiologia , Feminino , Humanos , Resultado do Tratamento , Vulva , Líquen Escleroso Vulvar/cirurgiaRESUMO
Vulvovaginal atrophy (VVA) has an impact on the quality of life (QoL) of women. This post hoc analysis of the EVES study provides an overview of the QoL in postmenopausal Italian women in relation with VVA severity. We included 1066 women attending menopause/gynaecologic centres. A face-to-face survey (including QoL and sexual life questionnaires), joining an objective gynaecological examination to confirm VVA, were performed. The 65.5% of the participants presented severe vaginal, vulvar and/or urinary symptoms; an 86.9% had an objective confirmed VVA. Women with severe symptoms presented with significantly worse QoL scores than the women without. We found there were moderately significant correlations between vaginal and vulvar symptoms' severity and lower overall DIVA QoL scores (p<.0005, in both cases). Women with a confirmed VVA presented worse QoL scores than women without confirmation. Our data suggest a clear relationship between VVA severity and a decrease in QoL in postmenopausal Italian women.IMPACT STATEMENTWhat is already known on this subject? Vulvovaginal atrophy (VVA) appears as a common chronic disorder in postmenopausal women that, as soon as the oestrogen levels decrease, becomes a severe condition affecting their quality of life (QoL).What do the results of this study add? We provide new insight about QoL related to VVA severity in Italian postmenopausal women. Our local data demonstrates that QoL in Italian women suffering from menopause is directly related to the severity of vaginal and vulvar symptoms. The same correlation exists for urinary symptoms. QoL is also reduced in patients with an objectively confirmed VVA diagnosis.What are the implications of these findings for clinical practice and/or further research? The implications of our findings involve the need for a better management, not only of the physical aspects of VVA, but also of the non-physical dimensions. Clinicians should ask for the impact of VVA on QoL aspects, making postmenopausal women aware about the possible affected spheres. Medical personnel should conduct future campaigns in the Italian general population, not only in those asking for medical help, to make all women conscious about this silent disorder affecting physical and non-physical dimensions and in order to treat it at early stages.