RESUMO
A cross-sectional study on five organized pig farms was conducted to assess the faecal carriage of ESBL and blaNDM carbapenemase-producing E. coli in piglets and pig farmworkers. Faecal samples from piglets (n = 155) and pig farmworkers (n = 21) were processed for isolation and characterization of E. coli. A total of 124 E. coli isolates from piglets and 21 E. coli isolates pig farmworkers were recovered and screening for ESBL production showed that 44.4 % (55/124) of the isolates from piglets and 42.9 % (9/21) of the isolates from farmworkers were ESBL positive. The ESBL positive isolates from piglets and farmworkers harbored blaCTX-M and also co-harbored other beta-lactams, sulphonamide, quinolone and tetracycline resistance genes. Diarrhoeic (50%, 49/98) and crossbred piglets (52.7%, 39/74) harbored a significantly higher number of ESBL producing isolates than non-diarrhoeic (23.1 %, 6/26) and purebred piglets (32%, 16/50) (p < 0.05). Piglets and pig farmworkers harbored nine and two carbapenem-resistant isolates, respectively. Interestingly, two isolates from piglets and one isolate from farmworkers harbored the blaNDM gene. The blaNDM positive E. coli isolated from piglets and farmworkers of the same farm revealed similar antibacterial resistance patterns, resistant genes, sequence (ST-167) and plasmid type (IncX3). In India, carbapenems are not used in food animal treatment, hence carbapenem resistant E. coli in piglets possibly originated from the human contact or common environment and is of public health importance.
Assuntos
Doenças dos Trabalhadores Agrícolas/microbiologia , Infecções por Escherichia coli/veterinária , Escherichia coli/enzimologia , Fezes/microbiologia , Doenças dos Suínos/transmissão , beta-Lactamases/metabolismo , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/epidemiologia , Animais , Antibacterianos/farmacologia , Estudos Transversais , Escherichia coli/classificação , Escherichia coli/genética , Infecções por Escherichia coli/tratamento farmacológico , Infecções por Escherichia coli/epidemiologia , Infecções por Escherichia coli/transmissão , Fazendeiros , Fezes/enzimologia , Feminino , Humanos , Índia/epidemiologia , Masculino , Testes de Sensibilidade Microbiana/veterinária , Suínos , Doenças dos Suínos/epidemiologia , Doenças dos Suínos/microbiologia , Zoonoses/microbiologia , Zoonoses/transmissão , beta-Lactamases/genéticaRESUMO
The patient was a 83-year- old male who worked as a farmer. He had complaints of weight loss, abdominal pain and joint pains for almost 5 months. Twenty days ago, the patient was checked at another hospital for complaints of occasional coughing and bloody sputum. He was treated with a diagnosis of pneumonia. His respiratory complaints were reduced, but there was no relief of his ongoing abdominal pain. Gastroduodenoscopy and colonoscopy were performed to examine for possible etiologies of continuous abdominal pain. Biopsies were taken from duodenal bulbus and second duodenal segment. Intense eosinophilic leukocyte infiltration and Strongyloides stercoralis larvae were observed in pathologic examination. The patient was successfully treated with albendazole 2x400 mg/day for 7+7 day.
Assuntos
Artrite Reumatoide/complicações , Duodeno/parasitologia , Pneumonia/complicações , Strongyloides stercoralis/isolamento & purificação , Estrongiloidíase/complicações , Dor Abdominal , Idoso de 80 Anos ou mais , Doenças dos Trabalhadores Agrícolas/diagnóstico , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/parasitologia , Albendazol/uso terapêutico , Animais , Anti-Helmínticos/uso terapêutico , Artralgia , Biópsia , Duodeno/patologia , Eosinofilia/complicações , Fazendeiros , Humanos , Larva , Masculino , Pneumonia/terapia , Strongyloides stercoralis/crescimento & desenvolvimento , Estrongiloidíase/diagnóstico , Estrongiloidíase/tratamento farmacológicoRESUMO
Mucormycosis has emerged as the third-most common fungal mycosis and is one of the most fatal molds. We herein report a case study of a 30-year-old woman who was a veterinarian, specializing in livestock, who developed disseminated mucormycosis during induction therapy for acute lymphoblastic leukemia. We successfully used a radical approach for treatment, including a surgical procedure and allogeneic transplantation, with continuous administration of antifungal agents. Reports of successful treatments are extremely rare, and our case has had the longest documented remission from disseminated disease. We speculate that our case's occupational environment may represent a risk factor for development of mucormycosis.
Assuntos
Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Antifúngicos/uso terapêutico , Transplante de Células-Tronco Hematopoéticas/métodos , Mucormicose/tratamento farmacológico , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicações , Médicos Veterinários , Doença Aguda , Adulto , Animais , Humanos , Hospedeiro Imunocomprometido , Gado , Masculino , Infecções Oportunistas/tratamento farmacológico , Leucemia-Linfoma Linfoblástico de Células Precursoras/terapia , Transplante Homólogo/métodos , Resultado do TratamentoRESUMO
Cryptococcal meningitis is an opportunistic infection predominantly affecting immunocompromised patients but rarely can affect the immunocompetent. We describe a 53-year-old Caucasian man who presented complaining of a 2-week history of severe bilateral eye pain and diplopia. His only known risk factor was that he lived in a horse farm and recently shot bats and pigeons in his barn. He visited an outside hospital during this time without a diagnosis established. After further deliberation, we obtained a lumbar puncture (LP) which revealed an opening pressure (OP) of 27 cm H2O. Cerebrospinal fluid (CSF) and fungal cultures confirmed the presence of Cryptococcus neoformans The patient was diagnosed with C. neoformans-mediated meningoencephalitis and was initiated on the appropriate induction anti-fungal therapy. This case emphasises the need for clinicians to remain vigilant and consider cryptococcal meningitis in immunocompetent individuals even when classic symptoms of meningitis are absent.
Assuntos
Doenças dos Trabalhadores Agrícolas/diagnóstico , Imunocompetência/fisiologia , Meningite Criptocócica/diagnóstico , Meningoencefalite/diagnóstico , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/microbiologia , Anfotericina B/administração & dosagem , Antifúngicos/administração & dosagem , Cryptococcus neoformans , Diplopia/microbiologia , Quimioterapia Combinada , Dor Ocular/microbiologia , Fluconazol/administração & dosagem , Humanos , Masculino , Meningite Criptocócica/tratamento farmacológico , Meningoencefalite/tratamento farmacológico , Meningoencefalite/microbiologia , Pessoa de Meia-Idade , Infecções Oportunistas/diagnóstico , Infecções Oportunistas/tratamento farmacológico , Doenças RarasRESUMO
INTRODUCTION: Green tobacco sickness occurs from transdermal absorption of chemicals from freshly harvested, green tobacco leaves. Signs and symptoms include nausea, vomiting, headache, and abdominal cramps. Prevalence has shifted from the United States and Europe to China, India, and Brazil. Worldwide 8 million individuals are afflicted, including women and children. Areas covered: Mecamylamine (Inversine®, Vecamyl®), a nicotinic acetylcholine receptor (nAChR) antagonist, should be tested as a remedy for green tobacco sickness. Mecamylamine is approved as an oral tablet for the treatment of hypertension, is safe, and is off-patent. Mecamylamine attenuates many of the effects of nicotine and tobacco including seizures, thereby supporting its use as an effective pharmacotherapy for tobacco dependence. Varenicline (Chantix®) and cytisine (Tabex®) are low efficacy (i.e. intrinsic activity) nAChR agonists, are used as smoking cessation aids, and are viable options to test as remedies against green tobacco sickness. Nicotine immunization strategies may provide further options for future testing. Expert commentary: Efforts to demonstrate reversal and/or prevention of green tobacco sickness by mecamylamine will underscore the importance of nicotine in this illness and highlight a new medication for effective treatment of tobacco poisoning.
Assuntos
Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Mecamilamina/uso terapêutico , Nicotiana/intoxicação , Doenças dos Trabalhadores Agrícolas/epidemiologia , Doenças dos Trabalhadores Agrícolas/fisiopatologia , Humanos , Mecamilamina/farmacologia , Nicotina/administração & dosagem , Nicotina/imunologia , Agonistas Nicotínicos/farmacologia , Agonistas Nicotínicos/uso terapêutico , Antagonistas Nicotínicos/farmacologia , Antagonistas Nicotínicos/uso terapêutico , Folhas de Planta , Vacinas/administração & dosagem , Vacinas/imunologia , Vareniclina/uso terapêuticoRESUMO
Bromoderma is a rare skin disease caused by the ingestion, inhalation, or contact with products containing bromides. We report a case of bromoderma in a 36-year-old farmer, characterized by remission during the spring and exacerbation during the winter. The recognition of the use of products containing bromides during the winter helped us to understand the cause of the clinical condition.
Assuntos
Doenças dos Trabalhadores Agrícolas/induzido quimicamente , Hidrocarbonetos Bromados/efeitos adversos , Exposição Ocupacional , Praguicidas/efeitos adversos , Estações do Ano , Pele/efeitos dos fármacos , Corticosteroides/uso terapêutico , Adulto , Doenças dos Trabalhadores Agrícolas/diagnóstico , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Antibacterianos/uso terapêutico , Biópsia , Luvas Protetoras , Humanos , Masculino , Recidiva , Indução de Remissão , Pele/patologia , Fatores de Tempo , Resultado do TratamentoAssuntos
Doenças dos Trabalhadores Agrícolas/diagnóstico , Cromoblastomicose/diagnóstico , Dermatoses da Mão/diagnóstico , Idoso , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Amputação Cirúrgica , Antifúngicos/uso terapêutico , Carcinoma de Células Escamosas/complicações , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/cirurgia , Cromoblastomicose/complicações , Cromoblastomicose/tratamento farmacológico , Diagnóstico Diferencial , Dedos/cirurgia , Dermatoses da Mão/complicações , Dermatoses da Mão/tratamento farmacológico , Humanos , Masculino , Recidiva Local de Neoplasia/complicações , Recidiva Local de Neoplasia/diagnóstico , Recidiva Local de Neoplasia/cirurgia , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/cirurgia , Microbiologia do SoloRESUMO
A previously healthy 67-year-old farmer presented to an outside hospital after a 2-week history of non-specific respiratory symptoms. A certain diagnosis was not initially apparent, and the patient was discharged home on a regimen for presumed chronic obstructive pulmonary disease exacerbation. He re-presented to the emergency department with shock and hypoxaemic respiratory failure requiring prompt intubation and fluid resuscitation. He was then transferred to our institution due to multiorgan failure. On arrival, the patient demonstrated refractory shock and worsening acute kidney injury, severe anaemia and thrombocytopaenia. The peripheral smear revealed absence of microangiopathic haemolytic anaemia. A closer review of the smear displayed red blood cell inclusion bodies consistent with babesiosis. The patient was started on clindamycin and loaded with intravenous quinidine, and subsequently transitioned to oral quinine. A red cell exchange transfusion was pursued with improvement of the parasite load. The patient was discharged home on clindamycin/quinine and scheduled for outpatient intermittent haemodialysis.
Assuntos
Doenças dos Trabalhadores Agrícolas/diagnóstico , Babesiose/diagnóstico , Insuficiência de Múltiplos Órgãos/parasitologia , Idoso , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Antiprotozoários/uso terapêutico , Babesia microti , Babesiose/tratamento farmacológico , Clindamicina/uso terapêutico , Transfusão de Eritrócitos/métodos , Humanos , Imunocompetência/fisiologia , Masculino , Quinidina/uso terapêutico , Quinina/uso terapêutico , Resultado do TratamentoAssuntos
Doenças dos Trabalhadores Agrícolas/diagnóstico , Dermatoses Faciais/diagnóstico , Esporotricose/diagnóstico , Idoso , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Antifúngicos/administração & dosagem , Dermatoses Faciais/tratamento farmacológico , Feminino , Humanos , Itraconazol/administração & dosagem , Esporotricose/tratamento farmacológicoAssuntos
Doenças dos Trabalhadores Agrícolas/microbiologia , Paracoccidioidomicose/diagnóstico , Doenças Testiculares/microbiologia , Adulto , Doenças dos Trabalhadores Agrícolas/diagnóstico , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Anfotericina B/uso terapêutico , Antifúngicos/uso terapêutico , Biópsia , Humanos , Imageamento por Ressonância Magnética , Masculino , Paracoccidioidomicose/tratamento farmacológico , Doenças Testiculares/diagnóstico , Doenças Testiculares/tratamento farmacológico , Tomografia Computadorizada por Raios X , Combinação Trimetoprima e Sulfametoxazol/uso terapêuticoRESUMO
A remarkable case of onychomycosis by Trichophyton (T.) rubrum combined with nail infestation by Tyrophagus (T.) putrescentiae in an elderly diabetic farmer is described and discussed. Large numbers of eggs and mites in all development stages were present in nail debris, reflecting active reproduction on site. Treatment with ivermectin 0.1% cream and environmental decontamination cleared the mite infestation, while onychomycosis responded well to oral terbinafine and ciclopirox 8% nail lacquer. Such a combination of onychomycosis and mite infestation of the same nail is an exceptional finding reported only twice in the literature.
Assuntos
Dermatoses do Pé/complicações , Infestações por Ácaros/complicações , Unhas/parasitologia , Onicomicose/complicações , Tinha dos Pés/complicações , Trichophyton/isolamento & purificação , Idoso , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/microbiologia , Criação de Animais Domésticos , Antifúngicos/uso terapêutico , Ciclopirox , Diabetes Mellitus Tipo 2/complicações , Suscetibilidade a Doenças , Dermatoses do Pé/microbiologia , Humanos , Ivermectina/uso terapêutico , Masculino , Naftalenos/uso terapêutico , Onicomicose/microbiologia , Permetrina , Piridonas/uso terapêutico , Sapatos , Terbinafina , Tinha dos Pés/microbiologiaAssuntos
Fármacos Dermatológicos/uso terapêutico , Granuloma de Células Gigantes/tratamento farmacológico , Hidroxicloroquina/uso terapêutico , Dermatoses do Couro Cabeludo/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Couro Cabeludo , Resultado do TratamentoRESUMO
BACKGROUND:: Histological and mycological changes during itraconazole use have not been totally established in chromoblastomycosis. OBJECTIVES:: To evaluate tissue modifications in chromoblastomycosis carriers under itraconazole treatment. METHODS:: A histological retrospective study of 20 cases of chromoblastomycosis seen at the university hospital at the south of Brazil, during itraconazole 400 mg daily treatment. Patients were classified into two groups: plaque or tumor lesions, and underwent periodic evaluations every four months during three years. Hematoxylin-eosin stain was used to analyze epidermal modifications, inflammatory infiltrate and fibrosis, and Fontana-Masson stain for parasite evaluation. RESULTS:: Fontana-Masson stain was superior to hematoxylin-eosin stain in fungal count in the epidermis (mean difference=0.14; p<0.05). The most distinct mycosis tissue responses were registered in the dermis. Epidermal thinning, granulomatous infiltrate decrease or disappearance, fibrosis increase and quantitative/morphological changes occurred during treatment. STUDY LIMITATIONS:: Patients could not be located to have their current skin condition examined. CONCLUSION:: Parasitic and tissue changes verified in this study can reflect the parasite-host dynamics under itraconazole action.
Assuntos
Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/microbiologia , Antifúngicos/uso terapêutico , Cromoblastomicose/tratamento farmacológico , Itraconazol/uso terapêutico , Pele/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças dos Trabalhadores Agrícolas/patologia , Biópsia , Cromoblastomicose/microbiologia , Cromoblastomicose/patologia , Feminino , Fungos/fisiologia , Interações Hospedeiro-Parasita/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Nitrato de Prata , Pele/microbiologia , Tela SubcutâneaAssuntos
Antibacterianos/uso terapêutico , Infecções por Mycobacterium não Tuberculosas/tratamento farmacológico , Tenossinovite/tratamento farmacológico , Adulto , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/microbiologia , Combinação Amoxicilina e Clavulanato de Potássio/uso terapêutico , Antibacterianos/administração & dosagem , Claritromicina/uso terapêutico , Contraindicações de Medicamentos , Farmacorresistência Bacteriana , Substituição de Medicamentos , Traumatismos dos Dedos/complicações , Traumatismos dos Dedos/microbiologia , Humanos , Masculino , Infecções por Mycobacterium não Tuberculosas/etiologia , Traumatismos Ocupacionais/microbiologia , Tenossinovite/etiologia , Tenossinovite/microbiologia , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Infecção dos Ferimentos/complicações , Infecção dos Ferimentos/microbiologiaRESUMO
Abstract: Background: Histological and mycological changes during itraconazole use have not been totally established in chromoblastomycosis. Objectives: To evaluate tissue modifications in chromoblastomycosis carriers under itraconazole treatment. Methods: A histological retrospective study of 20 cases of chromoblastomycosis seen at the university hospital at the south of Brazil, during itraconazole 400 mg daily treatment. Patients were classified into two groups: plaque or tumor lesions, and underwent periodic evaluations every four months during three years. Hematoxylin-eosin stain was used to analyze epidermal modifications, inflammatory infiltrate and fibrosis, and Fontana-Masson stain for parasite evaluation. Results: Fontana-Masson stain was superior to hematoxylin-eosin stain in fungal count in the epidermis (mean difference=0.14; p<0.05). The most distinct mycosis tissue responses were registered in the dermis. Epidermal thinning, granulomatous infiltrate decrease or disappearance, fibrosis increase and quantitative/morphological changes occurred during treatment. Study limitations: Patients could not be located to have their current skin condition examined. Conclusion: Parasitic and tissue changes verified in this study can reflect the parasite-host dynamics under itraconazole action.
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Pele/patologia , Cromoblastomicose/tratamento farmacológico , Itraconazol/uso terapêutico , Doenças dos Trabalhadores Agrícolas/microbiologia , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Antifúngicos/uso terapêutico , Nitrato de Prata , Pele/microbiologia , Biópsia , Estudos Retrospectivos , Cromoblastomicose/microbiologia , Cromoblastomicose/patologia , Tela Subcutânea , Doenças dos Trabalhadores Agrícolas/patologia , Fungos/fisiologia , Interações Hospedeiro-Parasita/fisiologiaAssuntos
Doenças dos Trabalhadores Agrícolas/etiologia , Dermatite Alérgica de Contato/etiologia , Jardinagem , Exposição Ocupacional/efeitos adversos , Plantas/efeitos adversos , Clima Tropical , Adulto , Doenças dos Trabalhadores Agrícolas/diagnóstico , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/tratamento farmacológico , Feminino , Glucocorticoides/administração & dosagem , Humanos , Testes do Emplastro , Prednisolona/administração & dosagem , Resultado do Tratamento , Local de TrabalhoAssuntos
Doenças dos Trabalhadores Agrícolas/microbiologia , Proteínas de Bactérias/genética , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Infecções Estafilocócicas/microbiologia , Idoso , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Animais , Antibacterianos/efeitos adversos , Antibacterianos/farmacologia , Antibacterianos/uso terapêutico , Proteínas de Bactérias/efeitos dos fármacos , Bélgica , Farmacorresistência Bacteriana Múltipla , Transferência Genética Horizontal , Humanos , Masculino , Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Staphylococcus aureus Resistente à Meticilina/genética , Testes de Sensibilidade Microbiana , Complicações Pós-Operatórias/tratamento farmacológico , Complicações Pós-Operatórias/microbiologia , Infecções dos Tecidos Moles/tratamento farmacológico , Infecções dos Tecidos Moles/microbiologia , Infecções Estafilocócicas/tratamento farmacológico , Infecções Cutâneas Estafilocócicas/tratamento farmacológico , Infecções Cutâneas Estafilocócicas/microbiologia , Zoonoses/microbiologiaRESUMO
Little is known about the impact of drug resistance on recurrence in TB. We conducted a cohort study to measure the impact of multi-drug resistance (MDR) on TB recurrence over nine years in Henan Province China. We reviewed medical records and conducted field interviews of 100 MDR and 150 non-MDR TB patients who were treated between 2001 and 2002. We compared long-term recurrence rates, risk factors, and outcomes in 2010 for 234 individuals who could be followed up. About one third (29.5%, 69/234) suffered recurrence after completion of treatment. The overall recurrence rate was 35/1,000 patient-years (PY), with a much higher rate (65/1,000 PY) among MDR-TB patients. MDR (HR: 2.75; CI: 1.58-4.79) and patient annual household income less than 10,000 Yuan (HR: 2.05; CI 1.11-3.80) were associated with recurrence. The mean time for recurrence among MDR-TB patients was 5.7 years, compared to 7.2 years among non-MDR-TB patients. Among the recurrence group members, 61.3% died, and 18.8% had failed treatments. We believe that the high TB recurrence rate after 9 years suggests that a high cure rate cannot accurately predict long-term outcome. We recommend that TB surveillance and control should be strengthened with a focus on MDR-TB and directly observed treatment, to reduce TB recurrence and transmission of MDR-TB.
Assuntos
Farmacorresistência Bacteriana Múltipla , Mycobacterium tuberculosis/efeitos dos fármacos , Tuberculose Resistente a Múltiplos Medicamentos/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças dos Trabalhadores Agrícolas/tratamento farmacológico , Doenças dos Trabalhadores Agrícolas/economia , Doenças dos Trabalhadores Agrícolas/epidemiologia , Antituberculosos/farmacologia , Antituberculosos/uso terapêutico , China/epidemiologia , Comorbidade , Feminino , Seguimentos , Humanos , Renda , Masculino , Pessoa de Meia-Idade , Recidiva , Fatores de Risco , Estudos de Amostragem , Fatores Socioeconômicos , Resultado do Tratamento , Tuberculose Resistente a Múltiplos Medicamentos/tratamento farmacológico , Tuberculose Resistente a Múltiplos Medicamentos/economia , Adulto JovemRESUMO
Cutaneous larva migrans (CLM) is a parasitosis frequently seen in persons who have travelled to tropical or subtropical regions and in those who have worked in contact with soil. The disease frequently develops due to Ancylostoma braziliensis and Ancylostoma caninum species. After penetrating the skin and entering the body, the hookworm larva proceeds to bore tunnels through the epidermis, creating pruritic, erythematous, serpiginous lesions. Secondary bacterial infections of the lesions can often be seen, especially on the legs and buttocks. In this article we presented three atypical local cases which have not been declared previously in our country. The first case, a 54-year-old male who was admitted to hospital in August with complaints of an obverse body rash and itching lasting for a week. Eruptions were observed over a small area on the right side of the abdomen, consisting of itchy, raised, erythematous, curvilinear string-like lesions. Moreover, no eosinophilia was detected in the patient, whose culture showed a growth of Streptococcus pyogenes. The patient was clinically diagnosed with CLM accompanied by secondary bacterial infection and treated for three days with 1 g of amoxicillin-clavulanic acid, mupirocin cream and albendazole 400 mg/d. Under this regime, the lesions were seen to decline. The second case, a 38-year-old male was also admitted in August, complaining of itching and redness on his body. The patient, whose blood count values were normal, exhibited itchy, raised, serpiginous string-like lesions located on the left side of his body. The patient, whose bacterial culture was negative, was clinically diagnosed as CLM and treated for three days with albendazole 400 mg/d and the lesions were seen to improve. The third case, a 23-year old male was admitted in September complaining of itching and redness on his neck. An itchy, crescent-shaped erythematous lesion was detected on his neck; bacteriological cultures and blood count were normal. The common feature for all three cases was the story of working in a hazelnut orchard and mowing weeds using a motorized string trimmer (weed whacker). None of them had a history of travel outside the country. Therefore CLM assumed to be occurred due to the aeration of surface earth layer with the force of motorized string trimmer and entrance of the larvae were from the open parts of the body. In conclusion, it should be keep in mind that hookworm larva-related CLM can be encountered in our country, and reporting of the patients with similar findings are necessary to determine the prevalence of this parasitosis in our country.