Peritonite encapsulante esclerosante em cão (Canis familiaris): relato de caso / Sclerosing encapsulating peritonitis in dog (Canis familiaris): case report

Um cão SRD, com cinco anos e histórico de ascite de evolução lenta com estruturas palpáveis foi submetido a exames clínicos, os quais foram inconclusivos. A laparotomia exploratória revelou que a cavidade abdominal estava repleta de líquido serossanguinolento e de múltiplos nódulos de diferentes tamanhos, com superfície irregular, aderidos aos peritônios visceral e parietal, sugestivos de neoplasia maligna. A eutanásia, seguida da necropsia para a coleta de amostras para o diagnóstico histopatológico, foi indicada. O exame anatomopatológico revelou nódulos sésseis e resistentes ao corte, constituídos de tecido conjuntivo fibroso e trabéculas ósseas em arranjo de osso esponjoso e osteoclastos em atividade. O diagnóstico definitivo foi peritonite encapsulante esclerosante.(AU)

A 5-year-old dog with chronic ascites was submitted to several clinical exams, which were inconclusive. Laparotomy revealed abdominal serosanguinous fluid and multiple nodules of several sizes with irregular surface, with visceral and parietal adhesion to the peritoneum, resembling malignant neoplasia. Euthanasia followed by necropsy and collection of samples to histopathological diagnosis was performed. Pathological exam revealed sessile nodules resistant to cut and the microscopy evaluation showed fibrous connective tissue and trabecular bone with sponge bone arrangement associated with active osteoclasts. The definitive diagnosis was sclerosing encapsulating peritonitis.(AU)

IMAGING DIAGNOSIS-SCLEROSING ENCAPSULATING PERITONITIS IN A DOG.

An approximately 5-month-old American Staffordshire terrier was presented with a history of recurrent peritoneal effusion. Abdominal radiographs and ultrasound showed a loculated effusion in the ventral abdomen with dorsal displacement of abdominal organs, hepatomegaly and rounding of liver and splenic margins. Computed tomography demonstrated centrally located gastrointestinal segments surrounded by a thin soft tissue band and a thickened peritoneal lining. At necropsy a fibrous membrane continuous with liver and splenic capsules encapsulated all abdominal organs. Microscopically the abdominal wall and fibrous capsule consisted of an irregular thick layer of hypocellular connective tissue. The final diagnosis was sclerosing encapsulating peritonitis.

Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog.

A 6-month-old male miniature pinscher dog developed chronic ascites, formation of fibrous membrane covering the abdominal organs, and numerous adhesions between the intestinal loops. The membrane and adhesions were surgically removed twice, but the dog died 1 month after initial presentation. Necropsy revealed recurrence of the membrane and intestinal adhesions. The fibrous membrane was composed of a thick layer of mature collagenous connective tissue, covered by immature collagenous connective tissue with mild lymphoplasmacytic infiltration, prominent neovascularization, and fibrin exudation. Similar fibrotic lesions were observed in the serosa of the liver, spleen, stomach and intestines. These findings are consistent with encapsulating peritoneal fibrosis reported in humans and dogs. The dog also had a maldeveloped liver, which is characterized by disorganized hepatic lobules and disarranged hepatic cords.