Hipopituitarismo como debut de absceso hipofisiario / Hypopituitarism as debut of pituitary abscess

We present a case of a 20 years old woman who consults for amenorrhea and mild hyperprolactinemia. Within the functional study hypopituitarism was discover and MRI showed a cystic lesion with “ring” enhancement. Transsphenoidal resection was performed, showing purulent material. Cultures were positive for MSSA and Neisseria cinerea. Antibiotic treatment was started completing 21 days. She evolved without relapse but did not recovered pituitary function.

Panhipopituitarismo y diabetes insípida secundarios a hipofisitis linfocitaria en una paciente con trisomia 12p / Panhypopituitarism and diabetes insipidus secondary to a lymphocytic hypophysitis in one patient with trisomy 12p

Lymphocytic hypophysitis (LH) is an uncommon inflammatory disease of the hypophysis. It's female to male ratio of appearance is 9:1. Pregnant women are more affected during the third trimester of pregnancy or postpartum. Clinical and radiological presentation can simulate a hypophyseal adenoma. We report a nonpregnant 13 years old adolescent, with a trisomy 12p, with panhypopituitarism, diabetes insipidus and a selar tumor. It was necessary to differentiate between a germinoma and a LH. The latter was confirmed with the hypophyseal biopsy.