Skeletal Bone Structure and Repair in Small Mammals, Birds, and Reptiles.

Bone strength depends on its structure, its composition, and the forces it is subjected to. Bone structure varies greatly between species and these differences may have clinical implications in their assessment or treatment. Fractures occur when the magnitude of the sum of forces affecting it exceeds its ultimate strength. The aim of bone healing is to recover the normal structure of the bone to maintain its normal function, but the mechanisms of bone healing differ greatly among species. This article provides a basic reference for the bone structure of small mammals, birds, and reptiles.

Eye Removal Surgeries in Exotic Pets.

This article covers considerations and techniques of eye removal surgeries in exotic pets. After issues including surgical indications, anesthesia, patient preparation, and instrumentation are explored, surgical techniques are described. Enucleation/exenteration and modified evisceration are discussed, with species-specific nuances of small mammals, birds, reptiles, snakes, amphibians, and fish highlighted.

Exotic Mammal Laparoscopy.

Laparoscopy is an evolving field in veterinary medicine, and there is an increased interest in using laparoscopic techniques in nondomestic mammals, including zoo animals, wildlife, and exotic pets. The aim of this article is to summarize the approach to laparoscopic procedures, including instrumentation, patient selection and preparation, and surgical approaches, and to review the current literature on laparoscopy in exotic mammals.

Endoscopic Ovariectomy of Exotic Mammals Using a Three-Port Approach.

Laparoscopic ovariectomy has been advocated as the preferred sterilization method for dogs for some time. The same arguments and benefits can be extended for many zoologic mammals, including carnivores, suids, primates, lagomorphs, and large rodents. This article summarizes the benefits, equipment options, surgical technique, recovery, and complications associated with this sterilization procedure.

OVARIECTOMY IN A COMMON HIPPOPOTAMUS (HIPPOPOTAMUS AMPHIBIUS).

Common hippopotami (Hippopotamus amphibius) introduced to Colombia in the 80s have since spread into livestock areas. Measures such as breeding control are needed to prevent further uncontrolled population growth. A young female hippopotamus was moved to a university veterinary hospital and anesthetized. Laparoscopic ovariectomy was attempted, but because of the difficulty of inserting the trocars in an apparently lax peritoneum, lateral laparotomy was performed. Both ovaries were transected with the use of an ultrasonic hemostatic device and clamping. Patient recovery was completely successful and the wound healed with few complications. To the authors' knowledge, this is the first report describing a successful ovariectomy in a hippopotamus.

Surgical castration of the male common hippopotamus (Hippopotamus amphibius).

In a prospective, clinical, surgery study we report here for the first time, in detail, on the surgical castration of 10 captive adult male common hippopotami (Hippopotamus amphibius). The successful procedures, a species-specific modification of standard equine castration techniques, provide valuable insight into the spatially dynamic nature of the common hippopotamus testis. The use of ultrasonography to locate the testis before and during the procedures and species-specific positioning during surgery greatly facilitated this distinctive procedure. Additionally, this surgical method provides an important additional tool for captive management of the common hippopotamus. Castration of individual males not only facilitates population control but can potentially also be employed to limit intermale aggression.

[Fractures and luxations in small mammals]. / Frakturen und Luxationen beim Kleinsäuger.

Most traumata in small mammals occur at home. Diagnosis and therapy can be compared with that in the dog and cat, but species-specific differences have to be considered. For fracture treatment a butterfly-cast can be sufficient for stabilization in special cases. In most cases satisfying results can be obtained with a "tie-in-fixator" treatment. Dislocations of the elbow joint are treated by reduction or stabilization through suture techniques or temporary arthrodesis.

An isolated cryptic peptide influences osteogenesis and bone remodeling in an adult mammalian model of digit amputation.

Biologic scaffolds composed of extracellular matrix (ECM) have been used successfully in preclinical models and humans for constructive remodeling of functional, site-appropriate tissue after injury. The mechanisms underlying ECM-mediated constructive remodeling are not completely understood, but scaffold degradation and site-directed recruitment of progenitor cells are thought to play critical roles. Previous studies have identified a cryptic peptide derived from the C-terminal telopeptide of collagen IIIα that has chemotactic activity for progenitor cells. The present study characterized the osteogenic activity of the same peptide in vitro and in vivo in an adult murine model of digit amputation. The present study showed that the cryptic peptide increased calcium deposition, alkaline phosphatase activity, and osteogenic gene expression in human perivascular stem cells in vitro. Treatment with the cryptic peptide in a murine model of mid-second phalanx digit amputation led to the formation of a bone nodule at the site of amputation. In addition to potential therapeutic implications for the treatment of bone injuries and facilitation of reconstructive surgical procedures, cryptic peptides with the ability to alter stem cell recruitment and differentiation at a site of injury may serve as powerful new tools for influencing stem cell fate in the local injury microenvironment.

Endoscopic intubation of exotic companion mammals.

Rabbits, guinea pigs, chinchillas and many other small exotic mammals are not intubated routinely, because intubation requires specialized equipment and is difficult to perfect. Using a face mask for these species solely on the basis that they are unable to regurgitate ignores the numerous other benefits of airway control. This article summarizes the many advantages of endotracheal intubation and the various methods of intubation that have been reported. It introduces endoscopic intubation as a method that overcomes many of the difficulties associated with other methods and describes the equipment needed, how to intubate with an endoscope, how to confirm proper endotracheal tube placement, and possible complications. Over-the-endoscope intubation is discussed in detail, as it appears to provide the most versatile and reliable method of intubating exotic companion mammals.

Anatomy of large animal spines and its comparison to the human spine: a systematic review.

Animal models have been commonly used for in vivo and in vitro spinal research. However, the extent to which animal models resemble the human spine has not been well known. We conducted a systematic review to compare the morphometric features of vertebrae between human and animal species, so as to give some suggestions on how to choose an appropriate animal model in spine research. A literature search of all English language peer-reviewed publications was conducted using PubMed, OVID, Springer and Elsevier (Science Direct) for the years 1980-2008. Two reviewers extracted data on the anatomy of large animal spines from the identified articles. Each anatomical study of animals had to include at least three vertebral levels. The anatomical data from all animal studies were compared with the existing data of the human spine in the literature. Of the papers retrieved, seven were included in the review. The animals in the studies involved baboon, sheep, porcine, calf and deer. Distinct anatomical differences of vertebrae were found between the human and each large animal spine. In cervical region, spines of the baboon and human are more similar as compared to other animals. In thoracic and lumbar regions, the mean pedicle height of all animals was greater than the human pedicles. There was similar mean pedicle width between animal and the human specimens, except in thoracic segments of sheep. The human spinal canal was wider and deeper in the anteroposterior plane than any of the animals. The mean human vertebral body width and depth were greater than that of the animals except in upper thoracic segments of the deer. However, the mean vertebral body height was lower than that of all animals. This paper provides a comprehensive review to compare vertebrae geometries of experimental animal models to the human vertebrae, and will help for choosing animal model in vivo and in vitro spine research. When the animal selected for spine research, the structural similarities and differences found in the animal studies must be kept in mind.

The use of surgical lasers in exotic and avian practice.

Use of diode laser energy with fiberoptic endoscopic delivery in exotic animal and avian practice offers a minimally invasive method for performing specific surgical procedures. Trauma and blood loss are minimized, but the absorption characteristics of the diode laser wavelengths (805/980 nm) must be considered to avoid potential postoperative complications due to collateral photothermal coagulative necrosis.