Effects of a Bio-Electromagnetic Energy Regulation Blanket on Thoracolumbar Epaxial Muscle Pain in Horses.

Back pain and inflammation of the epaxial musculature is a significant problem in all equine athletes. Treatment of back pain can be challenging and often requires a multimodal approach. In humans, bio-electromagnetic energy regulation therapy (BEMER) has been reported to be effective in pain modulation. With its increased use in people comes a similar robust application in veterinary medicine unfortunately, there is unsubstantiated evidence for this type of therapy in horses. Objectives of this study were to assess analgesic responses and biomechanical outcome variables using a bio-electromagnetic energy regulation therapy blanket, and to evaluate serum biomarkers as a method to monitor the treatment effects in horses with thoracolumbar epaxial muscle pain. Cohort study of 8 horses treated for 3 consecutive days. Horses with naturally-occurring thoracolumbar epaxial muscle pain were used in this study. Objective outcome variables were recorded daily for 5 days, which included spinal evaluation, mechanical nociceptive thresholds, electromyography, kinematics, kinetics, and serum biomarkers. BEMER blanket therapy significantly improved thoracolumbar epaxial muscle nociceptive thresholds. Center of pressure displacement as a measure of postural stability was significantly improved as well as significant gains in spinal flexibility were demonstrated at study completion. A significant treatment effect was not appreciated in measures of muscle tone, ground reaction forces or serum biomarkers. Limitations include the lack of a control group and a definitive structural diagnosis of thoracolumbar epaxial muscle pain. The BEMER blanket produced significant clinical and biomechanical effects in horses with back pain.

Impacts of DigestaWell NRG Supplementation on Post Exercise Muscle Soreness in Unconditioned Horses, a Pilot Study.

Exercising horses are commonly plagued by muscle fatigue and soreness, which can result in reduced performance ability. In the present study, ten unconditioned horses were fed 200g per day DigestaWell NRG, a commercial dietary supplement containing Yucca schidigera and Trigonella foenum-graecum, two herbs shown in other species to reduce post-exercise muscle pain and soreness. A control, unsupplemented group contained ten horses of similar age, breed, and gender. Horses completed a 50 minutes, ridden standardized exercise test of moderate intensity immediately prior to (Period1) and after 28 days of supplementation (Period2). Muscle soreness and tightness were evaluated 24 hours prior to and after each exercise test and used to determine the percent increase in post-exercise muscle soreness and tightness. Blood samples were collected before, and at 10 and 30 minutes, and 1, 4, and 24 hours post exercise. Plasma was analyzed for glucose, lactate, non-esterified fatty acid, tumor necrosis factor-α, and interleukin-1ß concentrations. Data were analyzed by repeated measures ANOVA using SAS Enterprise Guide v. 7.1. No changes in plasma parameters were indicated between periods for unsupplemented horses (P > 0.1) during Period2, excepting glucose, which was greater during Period2 (P = 0.018). Supplemented horses had lesser concentrations of tumor necrosis factor-α (P = 0.016) and lactate (P = 0.058) during Period2 than during Period1. During Period2, supplemented horses experienced a smaller percent increase in post exercise muscle soreness (P = 0.031). DigestaWell NRG supplementation may benefit unconditioned horses undergoing moderate intensity exercise through reducing lactate production and inflammation.

Effects of Overcheck Use on Stress Parameters and Welfare Implications in Driving Horses.

Three sequential studies were performed to evaluate the effects of tying horses while wearing overchecks (strap from the bridle to backpad). In an observational study, horses (n = 305) wore high (HC), low (LC), or no overchecks (NC) with frequencies of 29.2%, 51.8% and 19.0% respectively. Study 1 (Latin square, n = 6) consisted of a 90-min tie test (90TT) with treatments (HC, LC, NC) x periods (1-3). Horses wearing HC had higher plasma cortisol (P < 0.01) when compared to LC and NC. Muscle soreness (MSS) and tightness (MTS) were evaluated pre and 24 hr post 90TT and were higher (P < 0.01) 24 hrs after 90TT regardless of treatment. In study 2, in order to determine if acclimation to tying with overchecks could reduce the cortisol response in study 1, horses (n = 6) were tied 60 minutes/day for 2 weeks followed by a 60-min TT (60TT). Neither plasma cortisol nor heart rate were elevated above baseline levels, suggesting adaptation to novel stressors. Tying with restrictive HC appears to be a stressor, which may be reduced if an adaptation period is provided.

Comparison of Lactate Dehydrogenase Activity in Hive and Forager Honeybees May Indicate Delayed Onset Muscle Soreness - Preliminary Studies.

Active skeletal muscles produce lactate. H+ is generated during lactate neutralization in the Cori cycle, which leads to muscle acidosis and soreness (the so-called Delayed Onset Muscle Soreness, DOMS) in vertebrates. The aim of the study was to determine the activities/concentrations of compounds involved in the Cori cycle in worker and forager bees. Muscles, fat bodies, and hemolymph from 1- and 14-day-old workers and foragers were collected and assayed for the protein, lactate, glucose, NAD+, and NADH concentrations and lactate dehydrogenase (LDH) activity. Both lactate concentration and LDH activity in the hemolymph, muscles, and fat bodies increased with age. The concentrations of NAD+ and NADH in the tissues decreased with ageing/senescence, whereas protein concentrations increased until day 14 of bee's life and then decreased in foragers. The concentration of glucose decreased in the hemolymph and muscles and increased in the fat bodies. Elevated lactate concentrations in foragers may indicate transition from the aerobic to the anaerobic phase and development of metabolic acidosis that may eventually lead to muscle damage/soreness and shorter lifespan. When analyzing flight dynamics, load mass, and bee behavior, changes in the concentrations of Cori cycle compounds should be taken into account.

Pressure algometry measurement of canine muscular pain near the thoracolumbar junction: evaluation of a modified technique.

OBJECTIVE: To evaluate the utility of pressure algometry for measuring muscular pain in dogs by using a modified technique intended to prevent the development of a learned apprehension response. STUDY DESIGN: Prospective randomized clinical trial. ANIMALS: Sixty-three client-owned dogs with a history of restricted comfort or mobility. METHOD: Pressure algometry was used to measure the mechanical nociceptive threshold (MNT) in eight locations around the thoracolumbar junction. Dogs were assigned to one of two groups: group A dogs (n = 22) were placed on a restricted exercise program, while group B dogs (n = 25) were placed on a restricted exercise program and were administered combined acupuncture and manual therapy treatment (CAMT). After data collection in groups A and B was complete, animals were recruited for a third (control) group, C (n = 16), that had no exercise restriction or treatment. Algometry measurements were performed on four occasions over 28 days using a technique intended to prevent the dogs from developing a learned apprehension response. Measurements from eight locations were pooled and analyzed for changes over time. RESULTS: Increases in MNTs over time at all locations tested were identified in groups A and B. In group C there were no significant changes in MNT or evidence of a learned apprehension response. CONCLUSION AND CLINICAL RELEVANCE: MNTs in dogs without exercise restriction or CAMT were consistently repeatable and unchanged over time, indicating that there was no learned apprehension response to pressure algometry using the modified technique. Therefore, the increasing MNT values with time in dogs administered exercise restriction with or without CAMT suggests improved muscular comfort of the thoracolumbar region. Although further research is needed, use of this modified technique should improve the utility of pressure algometry for measuring muscular pain in dogs.