RESUMO
Introduction: Peripheral ossifying fibroma (POF) is a solitary gingival growth thought to arise from the gingiva, periosteum or the periodontal ligament. It is a slow-growing, benign, progressive lesion that is limited in size. Case description: This article describes a case of ossifying fibroma of a peripheral variant that occurred in a 26-year-old female in the anterior region of the lower jaw and presented as a growth on the gingiva. Since it was difficult to diagnose clinically, a pathological evaluation was mandatory. Upon pathological confirmation of the diagnosis, the lesion was surgically excised up to the periosteum. This was deemed to be the required treatment yet, since the recurrence rate is high for POF (8% to 20%), the patient must be followed up yearly to check for recurrence.
Introduction: Le fibrome ossifiant périphérique (FOP) est une excroissance gingivale solitaire dont on pense qu'elle provient des gencives, du périoste ou du ligament parodontal. Il s'agit d'une lésion progressive, bénigne et à croissance lente dont la taille est limitée. Description du cas: Cet article décrit le cas d'une variante périphérique du fibrome ossifiant survenue chez une femme de 26 ans, dans la région antérieure de sa mâchoire inférieure et se présentant comme une excroissance sur la gencive. Comme il était difficile d'établir un diagnostic clinique, une évaluation pathologique a été nécessaire. Après confirmation pathologique du diagnostic, la lésion a été excisée jusqu'au périoste lors d'une opération chirurgicale. On a jugé ce traitement nécessaire, puisque le taux de récidive du FOP est élevé (entre 8 % et 20 %). La patiente doit faire l'objet d'un suivi annuel pour rechercher toute récidive éventuelle.
Assuntos
Fibroma Ossificante , Neoplasias Gengivais , Humanos , Feminino , Fibroma Ossificante/cirurgia , Fibroma Ossificante/patologia , Fibroma Ossificante/diagnóstico , Fibroma Ossificante/diagnóstico por imagem , Adulto , Neoplasias Gengivais/cirurgia , Neoplasias Gengivais/patologia , Neoplasias Gengivais/diagnóstico , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/diagnóstico por imagem , Neoplasias Mandibulares/diagnósticoRESUMO
Telangiectatic osteosarcoma (TOS) is a rare variant of osteosarcoma that typically affects young individuals and long bones. The case under discussion was seen in the mandible of a 57-year-old female and had rapidly grown in size within a week. Microscopically, the tumour was characterised by large vascular cavities surrounded by anaplastic cells. Thin lacy tumour osteoid was observed at various foci. Abundant multinucleated osteoclastic giant cells along with areas of necrosis were also noted. The tumour cells were positive for SATB2, while negative for Cytokeratin AE1/3, CD 34. Ki-67 positivity was observed in more than 50% of tumour cells. A diagnosis of high grade telangiectatic osteosarcoma was thus made.
Assuntos
Neoplasias Mandibulares , Osteossarcoma , Telangiectasia , Humanos , Osteossarcoma/patologia , Osteossarcoma/química , Feminino , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico , Diagnóstico Diferencial , Pessoa de Meia-Idade , Telangiectasia/patologiaRESUMO
Odontoma is the most common odontogenic tumour derived from both epithelial and mesenchymal components of the tooth-forming apparatus. It is commonly diagnosed in the second and third decades of life when a radiograph is taken for some other purpose, as most cases are asymptomatic. This case involves a young boy, with the chief complaint of pain and swelling in the lower left back region. An intraoral examination revealed a carious and hypoplastic left permanent mandibular first molar. Although the molar was suspected as the source of his symptoms, radiographic imaging revealed multiple odontomas and missing second and third molar tooth buds. This case highlights the pathological effects of odontomas on surrounding teeth, including the malformation of the first molar and aplasia of the second and third molars. The sole management depends on the early diagnosis, histopathological examination to rule out malignancy and conservative surgical excision of these tissues.
Assuntos
Odontoma , Humanos , Masculino , Odontoma/patologia , Odontoma/cirurgia , Odontoma/diagnóstico , Odontoma/diagnóstico por imagem , Dente Molar/patologia , Dente Molar/diagnóstico por imagem , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico por imagem , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/diagnóstico , Criança , Diagnóstico DiferencialRESUMO
Odontome gelten zusammen mit den Amelo- blastomen als die häufigsten odontogenen Tumoren. Sie entstehen während der embryo- nalen Zahnkeimentwicklung durch fehlerhaft differenziertes Keimgewebe und werden daher auch als Hamartome bezeichnet. Somit sind sie also strenggenommen keine klassischen Neoplasien.
Assuntos
Odontoma , Humanos , Odontoma/cirurgia , Odontoma/diagnóstico , Odontoma/patologia , Adolescente , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico , Neoplasias Maxilares/cirurgia , Neoplasias Maxilares/patologia , Neoplasias Maxilares/diagnóstico , Masculino , Diagnóstico Diferencial , FemininoRESUMO
Salivary gland neoplasms account for 3% of all head and neck tumours. Pleomorphic adenoma (PA) is the most common salivary gland tumour that mainly occurs in the parotid gland, followed by minor salivary glands of the oral cavity, however, the occurrence of PA inside the jaw bones is exceedingly rare and very few cases have been reported in the literature. Inside jaw bones these lesions tend to imitate large osteolytic lesions encompass a diagnostic challenge. An exhaustive review of the literature revealed only 10 cases of central pleomorphic adenoma. We present a rare case of primary PA that occurred inside the mandible and was provisionally diagnosed as ameloblastoma.
Assuntos
Adenoma Pleomorfo , Ameloblastoma , Neoplasias Mandibulares , Humanos , Masculino , Adenoma Pleomorfo/diagnóstico , Adenoma Pleomorfo/patologia , Ameloblastoma/diagnóstico , Ameloblastoma/patologia , Diagnóstico Diferencial , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/patologia , AdultoRESUMO
BACKGROUND: A central giant cell granuloma (CGCG) is a benign, proliferative, intraosseous, and non-odontogenic lesion occurring primarily in children and young adults. On the histological level, it is characterized by numerous multinucleated giant cells scattered randomly throughout a sea of spindle-shaped mesenchymal stromal cells which are dispersed throughout the fibrovascular connective tissue stroma containing areas of haemorrhage. When it comes to radiographic features, CGCG can have an array of variations, ranging from well-defined expansile lesions to ill-defined and destructive lesions, with or without expansion. CASE PRESENTATION: This case report reviews an 11-year-old Caucasian patient with a chief complaint of slow-growing swelling involving the right posterior mandibular region. The cone beam computed tomography (CBCT) revealed an ill-defined mixed lesion mimicking both fibro-osseous lesion and hemangioma. However, microscopic examination revealed multinucleated giant cells in a fibrous stroma suggestive of central giant cell granuloma. CONCLUSION: Our intent in reporting this case is to highlight the importance of thorough clinical, radiographical and histopathological examination for accurate diagnosis and therapeutic interventions as well as to emphasize the importance of taking different possibilities into consideration when examining bony swellings in the head and neck region.
Assuntos
Tomografia Computadorizada de Feixe Cônico , Granuloma de Células Gigantes , Hemangioma , Criança , Humanos , Masculino , Diagnóstico Diferencial , Granuloma de Células Gigantes/diagnóstico por imagem , Granuloma de Células Gigantes/patologia , Granuloma de Células Gigantes/diagnóstico , Hemangioma/diagnóstico por imagem , Hemangioma/diagnóstico , Hemangioma/patologia , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Doenças Mandibulares/diagnóstico por imagem , Doenças Mandibulares/patologia , Doenças Mandibulares/diagnóstico , Neoplasias Mandibulares/diagnóstico por imagem , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnósticoRESUMO
Rhabdomyosarcoma with TFCP2-related fusions (TFCP2-RMS) is a rare entity that commonly affects young adults with a predilection for skeletal involvement. We herein report a 40-year-old female patient with TFCP2-RMS who was misdiagnosed as fibrous dysplasia or low-grade central osteosarcoma of the mandible by referring institutions. Histologically, the tumor showed dominant spindle cells and focal epithelioid cells with marked immature woven bone formation. Immunophenotypically, in addition to the characteristic expression of myogenic markers, ALK, and cytokeratins, tumor cells also unusually expressed osteogenic markers, such as MDM2 and SATB2. Through fluorescence in situ hybridization, the tumor cells showed EWSR1::TFCP2 gene fusion and no MDM2 gene amplification. This is a rare case of TFCP2-RMS, which was misdiagnosed as low-grade central osteosarcoma due to its presenting immunophenotype of MDM2 and SATB2, as well as extensive osteoid matrix formation.
Assuntos
Erros de Diagnóstico , Neoplasias Mandibulares , Osteossarcoma , Rabdomiossarcoma , Fatores de Transcrição , Humanos , Feminino , Adulto , Osteossarcoma/diagnóstico , Osteossarcoma/genética , Osteossarcoma/patologia , Fatores de Transcrição/genética , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/genética , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/diagnóstico por imagem , Rabdomiossarcoma/genética , Rabdomiossarcoma/diagnóstico , Rabdomiossarcoma/patologia , Proteínas de Ligação a DNA/genética , Diagnóstico Diferencial , Hibridização in Situ Fluorescente , Rearranjo Gênico , Biomarcadores Tumorais/genética , Displasia Fibrosa Óssea/genética , Displasia Fibrosa Óssea/diagnóstico , Displasia Fibrosa Óssea/patologia , Tomografia Computadorizada por Raios X , Radiografia PanorâmicaRESUMO
We report a rarely occurring hematologic neoplasm in a young adult. Hematologic neoplasms were first described in 2008 and are now included in both accepted tumor classification systems, i.e., International Consensus Classification and World Health Organization. This hematologic neoplasm shows a characteristic ALK positivity in immunohistochemical examination and correspondingly, ALK fusion genes in the molecular analysis. Pathologists should be aware of this entity, particularly as it is challenging to differentiate from other more frequent neoplasms of the same disease group or mesenchymal neoplasm with ALK aberration.
Assuntos
Osteólise , Humanos , Diagnóstico Diferencial , Osteólise/patologia , Osteólise/diagnóstico , Osteólise/diagnóstico por imagem , Osteólise/etiologia , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/genética , Masculino , Adulto , Quinase do Linfoma Anaplásico/genética , Adulto Jovem , FemininoRESUMO
OBJECTIVE: To describe a novel presentation of paraneoplastic hypercalcemia caused by a canine salivary carcinoma. ANIMAL: A 6-year-old intact male Husky with hypercalcemia and a spontaneous salivary carcinoma, stage III. CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES: The dog presented with polyuria, polydipsia, and hypercalcemia. Physical examination revealed a 37 X 43-mm firm mass in the ventrolateral aspect of the right-hand side of the neck, caudal to the temporomandibular joint. Incisional biopsy was suspicious of metastatic carcinoma to the mandibular lymph node. A full-body CT scan found a large, heterogenous, contrast-enhancing mass on the right ventrolateral neck that appeared to be originating from either the mandibular lymph node or right mandibular salivary gland. Parathyroid hormone-related protein was considered within normal reference intervals, and both parathyroid glands appeared ultrasonographically normal. TREATMENT AND OUTCOME: The patient was treated with a marginal surgical excision of the mass, without immediate complications. Histopathology confirmed the presence of a salivary carcinoma with narrow margins of excision and invasion of the mandibular lymph node. Twenty-four hours after surgery, ionized calcium returned to normal reference values and clinical signs completely resolved. CLINICAL RELEVANCE: Hypercalcemia is an urgent pathology with important systemic implications requiring prompt diagnosis and intervention. In this case report, we identify the first salivary carcinoma associated with a paraneoplastic hypercalcemia, including this pathology as a new differential diagnosis. The hypercalcemia resolved with marginal surgical excision, but interestingly the parathyroid hormone-related protein was not overexpressed, meaning that this neoplasia could mediate hypercalcemia by another pathophysiological mechanism.
Assuntos
Doenças do Cão , Hipercalcemia , Neoplasias das Glândulas Salivares , Animais , Hipercalcemia/veterinária , Hipercalcemia/etiologia , Doenças do Cão/diagnóstico , Doenças do Cão/patologia , Masculino , Cães , Neoplasias das Glândulas Salivares/veterinária , Neoplasias das Glândulas Salivares/complicações , Neoplasias das Glândulas Salivares/patologia , Neoplasias das Glândulas Salivares/diagnóstico , Síndromes Paraneoplásicas/veterinária , Síndromes Paraneoplásicas/diagnóstico , Carcinoma/veterinária , Carcinoma/complicações , Neoplasias Mandibulares/veterinária , Neoplasias Mandibulares/complicações , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnósticoRESUMO
Ewing sarcoma (ES) usually arises from long bones and affects the head and neck region in only 1%-4% of cases. We reported clinical, radiographic, cytomorphologic, and histomorphologic findings of the ES in the mandible, because of its rarity and radiologically misinterpreted as a parotid gland tumor. A 26-year-old male patient presented with a history of painfull cheek swelling. On magnetic resonance imaging, a mass measuring 50 × 48 × 45 mm was found eroding mandible and pushing back the parotid gland. Aspiration cytology was performed with suspicion of parotid gland tumor. Small, nucleated cells with nuclear indentation, inconspicuous nucleoli, and occasionally rosette-like arrangement were observed. Neuroendocrine immune markers were positive on cell block. It was diagnosed as small round cell neoplasm with neuroendocrine differentiation and biopsy was suggested. The differential diagnosis considered soft tissue and parotid gland tumors. The small round cell tumor morphology was seen on biopsy specimen and immunostaining was applied. The diagnosis for this case was ES of the mandible. ES of the mandible is unusual. Although the histogenesis is still unknown, various cells have been proposed as cells of origin namely, endothelial, hematopoietic, fibroblastic, mesenchymal stem cells or neural derived mesenchymal stem cells. Small cell morphology, CD99, CD56, neuron specific enolase, and synaptophysin expressions confirmed the diagnosis of ES. The differentiation of the ES from other small cell tumors may be difficult and requires awareness for histological and immunohistochemical features. It should be kept in mind that the diagnosis can be challenging due to uncommon locations and radiological misinterpreted.
Assuntos
Sarcoma de Ewing , Humanos , Masculino , Sarcoma de Ewing/patologia , Sarcoma de Ewing/diagnóstico , Adulto , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico , Diagnóstico Diferencial , Mandíbula/patologia , Biomarcadores Tumorais/metabolismoRESUMO
BACKGROUND: Adenoid ameloblastoma with dentinoid (AAD) is a hybrid odontogenic tumor comprising histopathological presentation of ameloblastoma (AM) and adenomatoid odontogenic tumor (AOT) along with extracellular dentinoid material. CASE PRESENTATION: A 35-year-old female reported an asymptomatic swelling in the left mandibular posterior region. Histopathological examination revealed composite features of AM with AOT along with dentinoid material, which stained positively with Van Gieson and trichrome stains. CONCLUSION: The present case report serves to add further to the modicum of literature reports pertaining to AAD, which may gain recognition as a distinct entity in future World Health Organization (WHO) classification of odontogenic tumors.
Assuntos
Ameloblastoma , Humanos , Feminino , Adulto , Ameloblastoma/patologia , Ameloblastoma/diagnóstico , Tumores Odontogênicos/patologia , Tumores Odontogênicos/diagnóstico , Tumores Odontogênicos/classificação , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico , Mandíbula/patologia , Mandíbula/diagnóstico por imagemRESUMO
Ameloblastoma is the most common benign odontogenic tumor with local invasion and high recurrence, which generally occurs in the jaw bones. Hypercalcemia is a common paraneoplastic syndrome that is commonly observed in patients with malignancies but rarely encountered in patients with benign tumors. Thus far, not many cases of ameloblastoma with hypercalcemia have been reported, and the pathogenic mechanism has not been studied in depth. This paper presents a case report of a 26-year-old male diagnosed with giant ameloblastoma of the mandible, accompanied by rare hypercalcemia. Additionally, a review of the relevant literature is conducted. This patient initially underwent marsupialization, yet this treatment was not effective, which indicated that the selection of the appropriate operation is of prime importance for improving the prognosis of patients with ameloblastoma. The tumor not only failed to shrink but gradually increased in size, accompanied by multiple complications including hypercalcemia, renal dysfunction, anemia, and cachexia. Due to the contradiction between the necessity of tumor resection and the patient's poor systemic condition, we implemented a multi-disciplinary team (MDT) meeting to better evaluate this patient's condition and design an individualized treatment strategy. The patient subsequently received a variety of interventions to improve the general conditions until he could tolerate surgery, and finally underwent the successful resection of giant ameloblastoma and reconstruction with vascularized fibular flap. No tumor recurrence or distance metastasis was observed during 5 years of follow-up. Additionally, the absence of hypercalcemia recurrence was also noted.
Assuntos
Ameloblastoma , Hipercalcemia , Neoplasias Mandibulares , Masculino , Humanos , Adulto , Ameloblastoma/complicações , Ameloblastoma/cirurgia , Ameloblastoma/diagnóstico , Hipercalcemia/etiologia , Neoplasias Mandibulares/complicações , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/diagnóstico , Recidiva Local de Neoplasia/patologia , Mandíbula/patologiaAssuntos
Cementoma , Fibroma Ossificante , Neoplasias Mandibulares , Osteossarcoma , Humanos , Fibroma Ossificante/diagnóstico , Fibroma Ossificante/cirurgia , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/cirurgia , Osteossarcoma/diagnóstico , Osteossarcoma/cirurgia , Relatos de Casos como AssuntoRESUMO
Ameloblastic carcinoma (AC) is a rare odontogenic malignant epithelial neoplasm of maxillofacial skeleton with a distinct predisposition of the mandible. It can occur in a wide range of age groups, with a sex predilection in males. It can arise either as a de novo lesion or from preexisting ameloblastoma. AC has a high propensity for local recurrence as well as distant metastasis (chiefly lungs), thus requiring an aggressive surgical approach and a strict surveillance. Owing to the rarity of publications describing AC, little is known about this entity in pediatric patients. We report a case of transformation of ameloblastoma into AC in a 10-year-old child.
Assuntos
Ameloblastoma , Carcinoma , Neoplasias Mandibulares , Tumores Odontogênicos , Masculino , Humanos , Criança , Ameloblastoma/diagnóstico , Ameloblastoma/cirurgia , Ameloblastoma/patologia , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/patologia , Tumores Odontogênicos/diagnóstico , Tumores Odontogênicos/cirurgia , Tumores Odontogênicos/patologia , Mandíbula/patologiaRESUMO
OBJECTIVE: Mandibular tumors in the pediatric population are rare. These malignancies are variable in their histology, and combined with their rarity, has made it difficult to describe their clinical course, and treatment guidelines. The aim of this paper is to describe the experience of Boston Children's Hospital, a pediatric tertiary referral center, with treating malignant mandibular malignancies, as well as provide multi-disciplinary team approach in managing this clinical entity. METHODS: A retrospective search was performed for mandibular malignancies in pediatric patients between 1995 and 2020 via the pathological database at Boston Children's Hospital. Only patients with malignant solid mandibular neoplasms were included, leaving 15 patients for final analysis. RESULTS: The median age at presentation was 10.1 ± 10.3 years. Nine of 15 patients (60%) presented with jaw mass which was the most common clinical presentation. The most commonly identified histological diagnosis was rhabdomayosarcoma and osteosarcoma (n = 4, 26% each). A mandibulectomy was performed in 12 (80%) cases. Reconstruction of the mandible was performed using a fibular free flap in 6 (40%) cases, and a plate in 3 (20%) cases. Mean follow-up was 4.6 ± 4.9 years. CONCLUSION: Malignant tumors most commonly present with a jaw mass, however asymptomatic and incidental presentations follow closely and pathologies can vary greatly. Surgical resection and reconstruction is often indicated, multidisciplinary tumor board review is required to determine when children are best treated with neo-/adjuvant treatment with chemo- and radiotherapy.
Assuntos
Retalhos de Tecido Biológico , Neoplasias Mandibulares , Procedimentos de Cirurgia Plástica , Humanos , Criança , Adolescente , Adulto Jovem , Adulto , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/cirurgia , Estudos Retrospectivos , Mandíbula/patologia , Transplante ÓsseoRESUMO
Background: Osteoma is a benign bone tumor that rarely affects animals. The most common bones involved with this tumor included the mandible, maxillofacial bones, and nasal sinuses. Definitive diagnosis is based on pathology findings which allow for differentiation with other bone lesions. Case Description: The patient, a 5-year-old intact male Mongrel dog presented with a huge mandibular mass that involved both the right and left mandible, and led to dental occlusion. The radiography was performed and depicted the intense mass with a well-demarcated edge, a short transitional zone between normal and abnormal bone, and a smooth rounded radiopaque appearance. The investigation according to the fine needle aspiration showed the presence of oval to spindle shape cells with poorly malignancy criteria, fatty cells, reactive osteoblasts, and osteoclasts based on a population of spindle-shaped cells, and low numbers of degenerated neutrophils, bacteria, and few macrophages. Then, the radiographic assessments and cytology findings demonstrated the osteoma and were referred for surgical intervention. A unilateral mandibulectomy was performed, and the lesion was sent to the histopathology laboratory. The histopathology evaluation showed osteocyte proliferation without malignancy features. The osteoblast cells also showed no atypical proliferation that endorses the osteoma tumor. Conclusion: Although mandibular and maxillofacial bone resection in small animals have different tolerations, this patient became a candidate for surgery for future better nutrition and prevention of facial deformity and dental malocclusion. Follow-up after osteoma is one of the most necessary post-operation treatments to check the regeneration of the mass. There are considerable data in this report that should regard this tumor as a possible differential diagnosis for mandibular tumors.
Assuntos
Doenças do Cão , Neoplasias Mandibulares , Osteoma , Cães , Masculino , Animais , Osteotomia Mandibular/veterinária , Osteotomia Mandibular/efeitos adversos , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/veterinária , Mandíbula/cirurgia , Mandíbula/patologia , Osteoma/diagnóstico , Osteoma/cirurgia , Osteoma/veterinária , Radiografia , Doenças do Cão/diagnóstico por imagem , Doenças do Cão/cirurgiaRESUMO
Introduction: Ameloblastic fibro-odontoma (AFO) is a benign odontogentic tumor without an aggressive behavior, unlike the similar ameloblastic fibroma. Case Presentation: A 9-year-old boy, with tooth eruption failure, underwent enucleation and curettage of a well-defined variable radiolucent and radio-opaque right mandible lesion. There was odontogenic epithelium with peripheral palisading in a loose myxoid stroma as well as a disorganized component of dentin, enamel, and cementum, features of an AFO. Conclusion: AFO is an odontogenic mixed tumor of epithelium and mesenchyme.
Assuntos
Neoplasias Mandibulares , Odontoma , Masculino , Humanos , Criança , Odontoma/diagnóstico , Odontoma/cirurgia , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/patologia , Epitélio/patologia , Cabeça/patologia , Tecido Conjuntivo/patologiaRESUMO
INTRODUCTION: Ossifying fibromas are rare, non-aggressive benign tumours of the bone, commonly involving the posterior mandible in middle-aged individuals with a female predilection. FINDINGS: Clinical manifestations include asymptomatic expansion of the mandible with infrequent maxillary lesions, pain, malocclusion, and compromised quality of life including aesthetic perception. Owing to multiplicity of features, tendency of recurrence, and possibility of malignant transformation, the diagnosis, treatment, and post-operative management of ossifying fibroma are always a challenge. TAKEAWAY LESSONS: Study aims to report a clinical case of extensive swelling involving the coronoid process and condyle on the right side to crossing the mid-line of the mandible with compromised functions and aesthetics. The article describes the clinical, histopathological, and radiological features of the case. The possible treatment and challenges encountered are discussed.
Assuntos
Fibroma Ossificante , Neoplasias Mandibulares , Humanos , Fibroma Ossificante/patologia , Fibroma Ossificante/diagnóstico , Fibroma Ossificante/diagnóstico por imagem , Fibroma Ossificante/cirurgia , Neoplasias Mandibulares/patologia , Neoplasias Mandibulares/diagnóstico por imagem , Neoplasias Mandibulares/diagnóstico , Neoplasias Mandibulares/cirurgia , Feminino , Radiografia Panorâmica , AdultoRESUMO
Ameloblastic fibroma (AF) is a benign mixed epithelial and mesenchymal odontogenic tumor. This was previously grouped in odontogenic tumor showing odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation. This report describes a case of ameloblastic fibroma in a 37-yearold male who came with the complain of swelling in the left side of lower jaw since one year. Enucleation of the mass followed by reconstruction was done six years back. However, after two years of initial treatment; radiographic findings suggested recurrence. Histopathological examination confirmed the diagnosis of ameloblastic fibroma. Patient had no clinical and radiographic evidence of recurrence in three and six months' follow-up. Because of the higher proliferative capacity and malignant degree of the mesenchymal component in the recurrent neoplasm, sarcomatous transformation may occur. Hence, a long term clinical and radiographical follow-up is essential due to its transformation into ameloblastic fibrosarcoma.