Assuntos
COVID-19/complicações , Coinfecção , Infecções por Vírus Epstein-Barr/complicações , Pitiríase Rósea/complicações , Infecções por Roseolovirus/complicações , Ativação Viral , Adolescente , Anticorpos Antivirais/sangue , Infecções por Vírus Epstein-Barr/virologia , Herpesvirus Humano 4/imunologia , Herpesvirus Humano 6/imunologia , Herpesvirus Humano 7/imunologia , Humanos , Masculino , Infecções por Roseolovirus/virologiaAssuntos
Anetodermia/etiologia , Impetigo/complicações , Pitiríase Rósea/complicações , Adulto , Humanos , MasculinoRESUMO
Pityriasis rosea is a common acute exanthema of unknown aetiology, which causes severe anxiety. In this study, the demographic data of pityriasis rosea patients, who presented to our clinic between 2013 and 2017, were prospectively recorded. The patients with a confirmed pityriasis rosea diagnosis were followed up for 4 years in order to investigate the recurrence rate. Of the clinically suspected patients, having a typical history of pityriasis rosea manifestations, a herald patch, and/or secondary coloured squamous lesions, 400 were confirmed by biopsy to have pityriasis rosea. The 4-year follow-up was completed in 212 patients, of whom 136 (64.2%) were female and 76 (35.8%) were male. The recurrence rate was determined as 25.9% at the end of the 4-year follow-up period.
Assuntos
Pitiríase Rósea/complicações , Pitiríase Rósea/patologia , Prurido/etiologia , Adulto , Biópsia , Feminino , Seguimentos , Humanos , Hipersensibilidade/complicações , Masculino , Estudos Prospectivos , Recidiva , Índice de Gravidade de Doença , Pele/patologia , Fatores de TempoRESUMO
RESUMEN A pesar de que la Pitiriasis Rosada se considera una condición cutánea benigna, en el marco del embarazo, hay estudios que relacionan la aparición de esta patología con complicaciones asociadas en el feto. Metodología: Se realiza un reporte de caso, prospectivo, a una mujer de 36 años chilena que presentó esta patología durante la semana 12 de gestación. El objetivo fue describir, la evolución y control y contrastar su evolución con la evidencia científica actual sobre esta temática. Resultados: Paciente presenta placas eritematodescamativas concordantes con diagnóstico de pitiriasis rosada (superficie afectada menos al 50% de su cuerpo), sin presentar enantema, ni síntomas sistémicos. Tuvo un recién nacido sano a las 38 semanas de gestación, sin presentar ningún efecto adverso de los que relaciona la literatura analizada. Conclusiones: Distintos estudios han estudiado los posibles efectos adversos en el feto en madres que han presentado Pitiriasis Rosada en el embarazo, sin embargo, en este reporte de caso no se presentaron complicaciones asociadas. Faltan estudios realizados en mayor cantidad de pacientes.
ABSTRACT Although Pityriasis Rosea is considered a benign cutaneous condition, in the context of pregnancy, there are studies that relate the appearance of this pathology with associated complications in the fetus. Methodology: A prospective case report was made to a 36-year-old Chilean woman who presented this pathology during the twelve weeks of pregnancy. The objective was to describe, the evolution and control and to contrast its evolution with the current scientific evidence on this subject. Results: Patient presents concordant erythematous-desquamative plaques with diagnosis of Pityriasis Rosea (surface affected less than 50% of his body), without presenting enanthem, nor systemic symptoms. Had a healthy newborn at 38 weeks of gestation, without presenting any adverse effect related to the analyzed literature. Conclusions: Different studies have studied the possible adverse effects on the fetus in mothers who have presented pityriasis rosea in pregnancy, however in this case report there were no associated complications. Missing studies in a greater number of patients.
Assuntos
Humanos , Feminino , Gravidez , Recém-Nascido , Adulto , Pitiríase Rósea/complicações , Pitiríase Rósea/diagnóstico , Pitiríase Rósea/prevenção & controle , Complicações na Gravidez , Pitiríase Rósea/patologia , Pitiríase Rósea/virologia , Herpesvirus Humano 6/isolamento & purificação , Herpesvirus Humano 7/isolamento & purificaçãoRESUMO
Pityriasis Rosea (PR) is a common skin disorderencountered in daily practice. Although its etiologyhas not been established, there has been widespreadresearch into possibilities. The lack of its characteristicmanifestations, specifically the herald patch andtruncal involvement, can lead to pitfalls in diagnosis.Whereas other conditions in the differential diagnosisshould be considered, PR can at times also manifest inan atypical manner. We wish to illustrate three casesof PR including those that presented with aphthousulcers, vesicles, and an inverse pattern.
Assuntos
Pitiríase Rósea/diagnóstico , Dermatopatias Vesiculobolhosas/diagnóstico , Estomatite Aftosa/diagnóstico , Administração Cutânea , Administração Oral , Corticosteroides/uso terapêutico , Antivirais/uso terapêutico , Emolientes/uso terapêutico , Antagonistas dos Receptores Histamínicos/uso terapêutico , Humanos , Pitiríase Rósea/complicações , Pitiríase Rósea/terapia , Dermatopatias Vesiculobolhosas/etiologia , Dermatopatias Vesiculobolhosas/terapia , Estomatite Aftosa/etiologia , Estomatite Aftosa/terapia , Terapia UltravioletaRESUMO
Pityriasis rosea is a dermatological disease with a well-documented clinical appearance, but less is known about causes and treatment. Bell's palsy is a neurological condition leading to acute idiopathic hemifacial paralysis. Recent studies indicate that human herpesvirus (HHV) 6-7 reactivation may be a contributing factor to both conditions. We report a case of the 2 concurrent diagnoses that supports a common contributing factor and suggests further awareness and research into the role HHV 6-7 may play in the aetiology of both conditions.
Assuntos
Paralisia de Bell/complicações , Pitiríase Rósea/complicações , Infecções por Roseolovirus/complicações , Aciclovir/uso terapêutico , Antivirais/uso terapêutico , Paralisia de Bell/tratamento farmacológico , Paralisia de Bell/virologia , Criança , Feminino , Glucocorticoides/uso terapêutico , Herpesvirus Humano 6 , Herpesvirus Humano 7 , Humanos , Pitiríase Rósea/tratamento farmacológico , Pitiríase Rósea/virologia , Prednisona/uso terapêutico , Infecções por Roseolovirus/tratamento farmacológico , Infecções por Roseolovirus/virologiaRESUMO
Itch in children is a very common symptom and is mainly related to a skin disease rather than an underlying systemic disorder. The most common dermatoses include atopic dermatitis, contact dermatitis, insect bites, scabies, and pediculosis capitis. There are specific diagnostic patterns which require the evaluation of a careful history and dermatological examination. For dermatological treatment, we have to consider that children, especially infants, show differences in physiology and pathophysiology, and also in pharmacokinetics and pharmacodynamics compared with adults.
Assuntos
Antipruriginosos/uso terapêutico , Antagonistas dos Receptores Histamínicos/uso terapêutico , Prurido/terapia , Acrodermatite/complicações , Acrodermatite/terapia , Varicela/complicações , Varicela/terapia , Criança , Pré-Escolar , Dermatite Atópica/complicações , Dermatite Atópica/terapia , Dermatite de Contato/complicações , Dermatite de Contato/terapia , Epidermólise Bolhosa/complicações , Epidermólise Bolhosa/terapia , Exantema/complicações , Exantema/terapia , Humanos , Lactente , Mordeduras e Picadas de Insetos/complicações , Inseticidas/uso terapêutico , Infestações por Piolhos/complicações , Infestações por Piolhos/tratamento farmacológico , Mastocitose/complicações , Mastocitose/tratamento farmacológico , Neurofibromatose 1/complicações , Neurofibromatose 1/terapia , Permetrina/uso terapêutico , Pitiríase Rósea/complicações , Pitiríase Rósea/terapia , Prurido/etiologia , Escabiose/complicações , Escabiose/tratamento farmacológico , Dermatoses do Couro Cabeludo/complicações , Dermatoses do Couro Cabeludo/tratamento farmacológico , Higiene da PeleRESUMO
Pityriasis rosea (PR) is an acute exanthematous skin disease that is likely due to reactivation of human herpesviruses (HHVs) 6b and 7. In contrast to herpes simplex and zoster (alphaherpesviruses), HHV-6b and -7 (betaherpesviruses) are not found predominantly in skin lesions. This difference in virion location may decrease the possibility of causing central nervous system infection through skin contamination, but the risk for hematogenous spread likely remains the same. This article uses the first-known epidural placement through active PR to illustrate risk-benefit considerations when deciding between neuraxial and general anesthesia for obstetric patients with PR.
Assuntos
Anestesia Epidural/métodos , Anestesia Obstétrica/métodos , Recesariana/métodos , Vértebras Lombares , Pitiríase Rósea/diagnóstico , Complicações na Gravidez/diagnóstico , Adulto , Feminino , Humanos , Pitiríase Rósea/complicações , Pitiríase Rósea/cirurgia , Gravidez , Complicações na Gravidez/cirurgiaAssuntos
Herpes Zoster/epidemiologia , Pitiríase Rósea/epidemiologia , Psoríase/complicações , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Herpes Zoster/complicações , Humanos , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Pitiríase Rósea/complicações , Prevalência , Adulto JovemRESUMO
Pityriasis rosea (PR) is an acute, self-limiting exanthematous disease, associated with the reactivation of the human herpesvirus 6 (HHV-6) and/or human herpesvirus 7 (HHV-7) that usually lasts 6-8 weeks. We studied, from a clinical and virological point of view, 12 patients in whom the features of PR lasted longer than 12 weeks, defining this form of the disease as persistent PR (PPR). As in typical PR, in most of the PPR patients the disease begins with a herald patch, but compared to typical PR, systemic symptoms and oral lesions are more common. Moreover, in PPR we found a persistent reactivation of HHV-6 and/or HHV-7 with higher viral loads than in typical PR, accounting for the unusual persistence of the illness, the more frequent and severer systemic symptoms and the oral lesions. In conclusion, we describe an unusual persistent form of PR, whose prevalence has probably been underestimated so far and which should be added to the other variants of PR.
Assuntos
Infecções por Herpesviridae/imunologia , Herpesvirus Humano 6/imunologia , Herpesvirus Humano 7/imunologia , Pitiríase Rósea/virologia , Adulto , Feminino , Infecções por Herpesviridae/complicações , Infecções por Herpesviridae/virologia , Humanos , Masculino , Pitiríase Rósea/complicações , Pitiríase Rósea/imunologia , Carga Viral , Adulto JovemRESUMO
BACKGROUND: Macrolides are prescribed in the treatment of pityriasis rosea despite conflicting results of the limited number of studies evaluating their role in its treatment. AIM: A randomized double-blind placebo-controlled trial was conducted to evaluate the effect of azithromycin on the clinical course of pityriasis rosea. METHODS: Seventy patients of pityriasis rosea were given either azithromycin (n=35) or placebo (n=35) and were followed-up at 2, 4 and 6 weeks. Pruritus was assessed in both groups using the visual analogue scale (VAS) . Change in the pityriasis rosea severity score (PRSS) and in the VAS were recorded as outcome measures and were compared statistically. RESULTS: The decrease in PRSS from baseline through 2, 4 and 6 weeks within both treatment (P<0.001) and placebo (P<0.001) arms was found to be statistically significant; however, this change was not significantly different in the two groups (P=0.179). Similarly, the decrease in VAS was found to be statistically significant within both groups (P<0.001); however, the change was comparable between the two groups (P<0.937). Analysis by Fisher's exact test did not find a significant difference between the two groups for PRSS and VAS. CONCLUSION: Azithromycin is not effective in pityriasis rosea and the use of macrolides for this disease should not be encouraged in clinical practice.
Assuntos
Antibacterianos/uso terapêutico , Azitromicina/uso terapêutico , Pitiríase Rósea/tratamento farmacológico , Adolescente , Adulto , Método Duplo-Cego , Feminino , Humanos , Masculino , Pitiríase Rósea/complicações , Estudos Prospectivos , Prurido/etiologia , Índice de Gravidade de Doença , Adulto JovemAssuntos
Hepatite C Crônica/complicações , Pitiríase Rósea/complicações , Adulto , Antivirais/uso terapêutico , Biópsia , DNA Viral/sangue , Quimioterapia Combinada , Feminino , Hepacivirus/genética , Hepatite C Crônica/diagnóstico , Hepatite C Crônica/tratamento farmacológico , Herpesvirus Humano 6/genética , Herpesvirus Humano 7/genética , Humanos , Interferon-alfa/uso terapêutico , Pitiríase Rósea/patologia , Pitiríase Rósea/virologia , Polietilenoglicóis/uso terapêutico , RNA Viral/sangue , Proteínas Recombinantes/uso terapêutico , Recidiva , Ribavirina/uso terapêutico , Ativação ViralAssuntos
Betametasona/administração & dosagem , Antagonistas dos Receptores Histamínicos/administração & dosagem , Pitiríase Rósea , Prurido/etiologia , Pele/patologia , Administração Oral , Administração Tópica , Adulto , Antipruriginosos/administração & dosagem , Diagnóstico Diferencial , Gerenciamento Clínico , Humanos , Masculino , Pitiríase Rósea/complicações , Pitiríase Rósea/diagnóstico , Pitiríase Rósea/tratamento farmacológico , Pitiríase Rósea/fisiopatologia , Prurido/tratamento farmacológico , Prurido/fisiopatologia , Remissão Espontânea , Resultado do TratamentoAssuntos
Herpes Simples/complicações , Herpesvirus Humano 2 , Pitiríase Rósea/complicações , Complicações Infecciosas na Gravidez/diagnóstico , Adulto , Feminino , Herpes Simples/virologia , Herpesvirus Humano 2/patogenicidade , Humanos , Pitiríase Rósea/etiologia , Gravidez , Complicações Infecciosas na Gravidez/virologiaRESUMO
BACKGROUND: Few researchers have specifically evaluated how the quality of life of patients with pityriasis rosea (PR) and tinea versicolor (TV) are affected. There are even less studies exploring the psychological status of these patients. The objective of this study was to investigate and compare quality of life and psychological status of patients with PR and TV. METHOD: Thirty-six patients with pityriasis rosea and 43 patients with tinea versicolor (N = 79) were selected for the study. All patients were required to complete Dermatology Life Quality Index (DLQI) and Hospital Anxiety and Depression (HAD), Hospital Anxiety and Depression-Depression (HAD-D), and Hospital Anxiety and Depression-Anxiety (HAD-A) scales. RESULTS: Both groups did not differ from each other with regard to DLQI, HAD-D, HAD-A, and total HAD scores (p > 0.05). With regard to cutoff points of HAD-A, 11 patients in the PR group and 15 patients in the TV group had anxiety. The number of patients with depression in pityriasis rosea and tinea versicolor groups were 11 and 13 respectively. Depression and anxiety scores were highly correlated with DLQI scores in both patients with PR and TV. CONCLUSIONS: Results of the present study indicate that patients with PR and TV are at risk for psychopathology. Uncertainties about the etiology and length of recovery period in PR and location of disease to visible parts and recurrent nature of the disease in TV groups might have affected the patients' psychological status.