RESUMO
AIMS: Transcatheter tricuspid edge-to-edge repair (T-TEER) has gained widespread use for the treatment of tricuspid regurgitation (TR) in symptomatic patients with high operative risk. Although secondary TR is the most common pathology, some patients exhibit primary or predominantly primary TR. Characterization of patients with these pathologies in the T-TEER context has not been systematically performed. METHODS AND RESULTS: Patients assigned to T-TEER by the interdisciplinary heart team were consecutively recruited in two European centres over 4 years. Echocardiographic images were evaluated to distinguish between primary and secondary causes of TR. Both groups were compared concerning procedural results. A total of 339 patients were recruited, 13% with primary TR and 87% with secondary TR. Patients with primary TR had a smaller right ventricle (basal diameter 45 vs. 49â mm, P = 0.004), a better right ventricular function (fractional area change 45 vs. 41%, P = 0.001), a smaller right (28 vs. 34â cm2, P = 0.021) and left (52 vs. 67â mL/m2, P = 0.038) atrium, and a better left ventricular ejection fraction (60 vs. 52%, P = 0.005). The severity of TR was similar in primary and secondary TR at baseline (TR vena contracta width pre-interventional 13 ± 4 vs. 14 ± 5â mm, P = 0.19), and T-TEER significantly reduced TR in both groups (TR vena contracta width post-interventional 4 ± 3 vs. 5 ± 5â mm, P = 0.10). These findings remained stable after propensity score matching. Complications were similar between both groups. CONCLUSION: T-TEER confers equally safe and effective reduction of TR in patients with primary and secondary TR.
Assuntos
Implante de Prótese de Valva Cardíaca , Insuficiência da Valva Tricúspide , Prolapso da Valva Tricúspide , Humanos , Insuficiência da Valva Tricúspide/diagnóstico por imagem , Insuficiência da Valva Tricúspide/cirurgia , Insuficiência da Valva Tricúspide/etiologia , Valva Tricúspide/cirurgia , Prolapso da Valva Tricúspide/etiologia , Prolapso da Valva Tricúspide/cirurgia , Volume Sistólico , Estudos de Viabilidade , Resultado do Tratamento , Função Ventricular Esquerda , Implante de Prótese de Valva Cardíaca/métodos , Cateterismo Cardíaco/métodosAssuntos
Neoplasias Cardíacas/diagnóstico , Prolapso da Valva Mitral/diagnóstico , Mixoma/diagnóstico , Prolapso da Valva Tricúspide/diagnóstico , Adulto , Infarto Cerebral/etiologia , Ecocardiografia , Feminino , Neoplasias Cardíacas/complicações , Humanos , Prolapso da Valva Mitral/etiologia , Imagem Multimodal , Mixoma/complicações , Tomografia Computadorizada por Raios X , Prolapso da Valva Tricúspide/etiologiaAssuntos
Insuficiência Cardíaca/terapia , Coração Auxiliar/efeitos adversos , Prolapso da Valva Tricúspide/etiologia , Diagnóstico Diferencial , Ecocardiografia Transesofagiana , Humanos , Imagem Cinética por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Falha de Prótese , Prolapso da Valva Tricúspide/diagnósticoRESUMO
Ebstein's anomaly of the tricuspid valve is a rare lesion comprising less than 1% of patients with congenital heart disease. Among congenital heart lesions, Ebstein's anomaly is one of the most diverse in presentation, severity, and management. In its most severe form, it is also one of the most lethal. In this article we present a case of a patient who developed cardiac symptoms in adulthood. We follow this with a review of the pathology, clinical presentation, evaluation, and management of Ebstein's anomaly.
Assuntos
Anomalia de Ebstein/complicações , Anomalia de Ebstein/cirurgia , Prolapso da Valva Tricúspide/cirurgia , Disfunção Ventricular Direita/cirurgia , Adulto , Feminino , Humanos , Resultado do Tratamento , Prolapso da Valva Tricúspide/diagnóstico , Prolapso da Valva Tricúspide/etiologia , Disfunção Ventricular Direita/diagnóstico , Disfunção Ventricular Direita/etiologiaAssuntos
Carcinoma de Células Renais/diagnóstico por imagem , Neoplasias Cardíacas/diagnóstico por imagem , Neoplasias Renais/diagnóstico por imagem , Idoso , Ecocardiografia , Feminino , Ventrículos do Coração , Humanos , Invasividade Neoplásica , Prolapso da Valva Tricúspide/diagnóstico por imagem , Prolapso da Valva Tricúspide/etiologiaAssuntos
Traumatismos Cardíacos/complicações , Insuficiência da Valva Tricúspide/etiologia , Acidentes de Trânsito , Adulto , Dor no Peito/etiologia , Dispneia/etiologia , Ecocardiografia Transesofagiana , Traumatismos Cardíacos/diagnóstico por imagem , Ventrículos do Coração/lesões , Humanos , Cuidados Intraoperatórios , Masculino , Motocicletas , Insuficiência da Valva Tricúspide/diagnóstico por imagem , Prolapso da Valva Tricúspide/diagnóstico por imagem , Prolapso da Valva Tricúspide/etiologia , Ferimentos não Penetrantes/complicaçõesAssuntos
Cateterismo Venoso Central/efeitos adversos , Cardiopatias/etiologia , Trombose/etiologia , Cateteres de Demora/efeitos adversos , Remoção de Dispositivo , Ecocardiografia , Feminino , Átrios do Coração/diagnóstico por imagem , Átrios do Coração/patologia , Cardiopatias/diagnóstico , Humanos , Pessoa de Meia-Idade , Trombose/diagnóstico , Prolapso da Valva Tricúspide/diagnóstico , Prolapso da Valva Tricúspide/etiologiaAssuntos
Cateterismo Cardíaco/efeitos adversos , Desferroxamina/uso terapêutico , Cardiopatias/etiologia , Quelantes de Ferro/uso terapêutico , Trombose/etiologia , Talassemia beta/tratamento farmacológico , Adolescente , Calcinose/etiologia , Calcinose/cirurgia , Cardiomiopatias/etiologia , Cardiomiopatias/cirurgia , Cateteres de Demora/efeitos adversos , Átrios do Coração , Cardiopatias/diagnóstico por imagem , Cardiopatias/cirurgia , Humanos , Achados Incidentais , Masculino , Trombose/diagnóstico por imagem , Trombose/cirurgia , Prolapso da Valva Tricúspide/etiologia , Prolapso da Valva Tricúspide/cirurgia , Ultrassonografia , Talassemia beta/complicaçõesRESUMO
Two surgical patients are presented with tricuspid valve prolapse. One had severe isolated prolapse of the posterior leaflet at its junction with the anterior leaflet accompanied by chordal elongation that was successfully repaired; the other had mild prolapse of all three leaflets with chordal elongation. Myxomatous degeneration of the tricuspid valve was the suspected underlying pathologic disorder in both patients and was histologically proven in the resected leaflet tissue of patient 1.
Assuntos
Prolapso da Valva Tricúspide/etiologia , Idoso , Feminino , Humanos , Masculino , Valva Tricúspide/patologia , Prolapso da Valva Tricúspide/patologia , Prolapso da Valva Tricúspide/cirurgiaRESUMO
A case of severe tricuspid insufficiency with ruptured chordae tendineae due to nonpenetrating major chest trauma caused by a car accident is described. Electrocardiographic signs of complete right bundle branch block and olosystolic murmur were present and not observed before. Transthoracic echocardiography showed a significant prolapse of the septal tricuspid leaflet with severe tricuspid regurgitation and severe right heart overload, which progressively worsened. Transesophageal echocardiography confirmed the transthoracic echocardiographic findings. It also demonstrated the presence of ruptured chordae tendineae and the coexistence of a severe prolapse of the tricuspid anterior leaflet with flail movement. Although the patient remained asymptomatic, these findings prompted us to refer the case to the surgeon. The patient underwent valvuloplasty with excellent late result. In presence of traumatic tricuspid insufficiency the use of transesophageal echocardiography can be helpful to optimize the anatomic evaluation of the valvular apparatus allowing adequate therapeutic decision.
Assuntos
Cordas Tendinosas/lesões , Ecocardiografia Transesofagiana , Traumatismos Torácicos , Insuficiência da Valva Tricúspide/etiologia , Ferimentos não Penetrantes , Adulto , Feminino , Humanos , Masculino , Ruptura , Insuficiência da Valva Tricúspide/diagnóstico , Insuficiência da Valva Tricúspide/cirurgia , Prolapso da Valva Tricúspide/diagnóstico , Prolapso da Valva Tricúspide/etiologia , Prolapso da Valva Tricúspide/cirurgiaRESUMO
Tricuspid valve prolapse is an infrequent echocardiographic finding that is most commonly associated with mitral valve prolapse. When compared with patients exhibiting isolated prolapse of the mitral valve, patients with tricuspid valve prolapse are somewhat older individuals with a slightly higher frequency of neurologic symptoms, fatigue, weakness, supraventricular arrhythmias (especially atrial fibrillation) and skeletal deformities. Tricuspid valve prolapse may serve as a marker of more-diffuse connective tissue abnormalities, and its identification also should prompt an echocardiographic search for evidence of prolapse and regurgitation of the other heart valves.
Assuntos
Doenças das Valvas Cardíacas/patologia , Prolapso da Valva Tricúspide/patologia , Adulto , Criança , Ecocardiografia , Cardiopatias Congênitas/complicações , Insuficiência Cardíaca/complicações , Humanos , Estenose da Valva Mitral/complicações , Radiografia , Prolapso da Valva Tricúspide/diagnóstico , Prolapso da Valva Tricúspide/diagnóstico por imagem , Prolapso da Valva Tricúspide/etiologiaRESUMO
Echocardiographic findings in six patients with primary pulmonary hypertension are presented. Four of six patients had abnormal septal motion with prolapse of mitral and tricuspid valves. The other two had none of the three echocardiographic abnormalities. It is possible that hemodynamic changes in ventricular pressure gradients across the interventricular septum cause an abnormal septal motion and secondary AV valve prolapse.