1.
J Med Primatol
; 53(4): e12726, 2024 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-39073161
RESUMO
Historically, to generate Simian Retrovirus (SRV) positive control materials, we performed in vivo passage by inoculating uninfected rhesus macaques with whole blood from an SRV-1 infected (antibody and PCR positive) macaque. However, recent attempts using this approach have failed. This study reports observations and explores why it has become more difficult to transmit SRV via in vivo passage.