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1.
BMC Res Notes ; 17(1): 128, 2024 May 06.
Artigo em Inglês | MEDLINE | ID: mdl-38711110

RESUMO

The elemental composition of chemical elements can vary between healthy and diseased tissues, providing essential insights into metabolic processes in physiological and diseased states. This study aimed to evaluate the calcium (Ca) and phosphorus (P) levels in the bones of rats with/without streptozotocin-induced diabetes and/or exposure to infrasound. X-ray fluorescence spectroscopy was used to determine the concentrations of Ca and P in Wistar rat tibiae samples.The results showed a significant decrease in bone P concentration in streptozotocin-induced diabetic rats compared to untreated animals. Similarly, the Ca/P ratio was higher in the streptozotocin-induced diabetic group. No significant differences were observed in bone Ca concentration between the studied groups or between animals exposed and not exposed to infrasound.Moreover, streptozotocin-induced diabetic rats had lower bone P concentration but unaltered bone Ca concentration compared to untreated rats. Infrasound exposure did not impact bone Ca or P levels. The reduced bone P concentration may be associated with an increased risk of bone fractures in diabetes.


Assuntos
Cálcio , Diabetes Mellitus Experimental , Fósforo , Ratos Wistar , Estreptozocina , Animais , Diabetes Mellitus Experimental/metabolismo , Diabetes Mellitus Experimental/induzido quimicamente , Fósforo/metabolismo , Cálcio/metabolismo , Ratos , Masculino , Espectrometria por Raios X , Tíbia/metabolismo , Som/efeitos adversos , Osso e Ossos/metabolismo , Intolerância à Glucose/metabolismo
2.
BMC Oral Health ; 24(1): 265, 2024 Feb 23.
Artigo em Inglês | MEDLINE | ID: mdl-38389070

RESUMO

BACKGROUND: Dental anxiety is very much common among the patients and could be due to different factors like the behavior of the dentist, past experiences, Needle phobia, or word of mouth from other patients. According to recent studies, a strong association between sound and anxiety has been found, so this observational study has been conducted to find out the link between the activation of anxiety with the sound of a handpiece between experienced patients, who have already gone through the dental treatments and non-experienced patients. METHODS: Total of 297 participants were part of this study. These participants were divided into 2 groups according to the experienced and non-experienced dental patients. The researcher first filled out the CORAH Dental Anxiety Scale (DAS) form to mark the anxiety level of the patients, and then noted the readings of the heart rate in 3 intervals which were before during, and after the treatment with the pulse oximeter. Later the data was analysed using the SPSS independent t-test. RESULTS: Results show that patients in group 1 who have gone through the dental treatment before were less anxious and had a lesser effect on their heart rate than the patient who were having the treatment for the first time who were in group 2. Another interesting factor was noticed that in both the groups female were found to be more anxious than male participants. Participants with younger age were found to be more anxious than older age patient in both groups CONCLUSIONS: The sound of the handpiece can provoke anxiety in the patient, affecting the heart and increasing the heart rate. Participants who were experienced were found to be less anxious than the participants who were inexperienced.


Assuntos
Ansiedade ao Tratamento Odontológico , Transtornos Fóbicos , Som , Feminino , Humanos , Masculino , Ansiedade ao Tratamento Odontológico/etiologia , Ansiedade ao Tratamento Odontológico/fisiopatologia , Ansiedade ao Tratamento Odontológico/psicologia , Frequência Cardíaca , Transtornos Fóbicos/etiologia , Transtornos Fóbicos/fisiopatologia , Transtornos Fóbicos/psicologia , Som/efeitos adversos , Agulhas/efeitos adversos
4.
Sci Rep ; 12(1): 1973, 2022 02 07.
Artigo em Inglês | MEDLINE | ID: mdl-35132140

RESUMO

Experimental research has shown that beaked whales exhibit strong avoidance reactions to naval active sonars used during antisubmarine warfare training exercises, including cessation of echolocation and foraging activity. Behavioural responses to sonar have also been linked to strandings and mortality. Much of the research on the responses of beaked whales and other cetaceans to naval active sonar has occurred on or near U.S. naval training ranges, and the impacts of sonar in other regions remain poorly understood, particularly as these impacts, including mortality, are likely to go unobserved in offshore areas. In September 2016 the multinational naval exercise 'CUTLASS FURY 2016' (CF16) was conducted off eastern Canada. We used passive acoustic recordings collected in the region to quantify the occurrence and characteristics of sonar signals, measure ambient noise levels, and assess changes in the acoustic activity of beaked and sperm whales. The number of hours per day with echolocation clicks from Cuvier's beaked whales and sperm whales were significantly reduced during CF16, compared to the pre-exercise period in 2016 (sperm whales) and to control data from 2015 (both species). Clicks from an unidentified Mesoplodont beaked whale species, sporadically detected prior to CF16, were absent during the exercise and for 7 days afterward. These results suggest that beaked and sperm whales ceased foraging in the vicinity of CF16 and likely avoided the affected area. Such disturbance may have energetic, health, and fitness consequences.


Assuntos
Ecolocação , Som/efeitos adversos , Cachalote/fisiologia , Cachalote/psicologia , Guerra , Baleias/fisiologia , Baleias/psicologia , Animais , Aprendizagem da Esquiva , Canadá , Mergulho , Comportamento Alimentar
5.
Medicine (Baltimore) ; 100(41): e27509, 2021 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-34731137

RESUMO

BACKGROUND: Tinnitus is a common otological symptom and can be debilitating. Sound therapy has increased in popularity due to its potential for increased efficacy and fewer and milder side effects, but the available evidence is limited by the lack of randomized controlled trials comparing different sound therapies for tinnitus. Network meta-analysis (NMA) is a useful tool to compare multiple treatments when there is limited or no direct evidence available. The aim of this paper is to evaluate the efficacy and acceptability of different sound therapies for tinnitus. METHODS AND ANALYSIS: A literature search was conducted to identify articles in EMBASE, PubMed/MEDLINE, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Chinese Biomedical Literature, and Wanfang and Weipu from inception to April 1, 2021. The Tinnitus Handicap Inventory, Tinnitus Questionnaire, and effective rate were used to assess perceived tinnitus suppression after treatment. We used Review Manager 5.4 for the standard meta-analysis; R 4.0.4 and Stata 15.1 were used for the NMA and the publication bias and sensitivity analyses. RESULTS: The effect estimates of the direct comparisons (when available) were very similar to those of the NMA. Overall, sound stimulation alone performed better than medication alone, educational consultation alone, and no treatment. Combination therapy, such as sound stimulation plus educational consultation and sound stimulation plus drug therapy, yielded significantly better outcomes with regard to the alleviation of tinnitus than individual treatments. CONCLUSION: This is the first NMA to evaluate and compare the effectiveness of different sound therapies for the management of tinnitus. It may help inform the selection of sound therapy and the development of guidelines in clinical practice. Future studies of sound therapy with larger sample sizes involving multiple medical centers are needed to improve the current evidence.


Assuntos
Estimulação Acústica , Avaliação Educacional , Som , Zumbido , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estimulação Acústica/métodos , China/epidemiologia , Avaliação Educacional/métodos , Metanálise em Rede , Aceitação pelo Paciente de Cuidados de Saúde , Padrões de Prática Médica , Sensibilidade e Especificidade , Som/efeitos adversos , Zumbido/terapia , Resultado do Tratamento , Metanálise como Assunto , Revisões Sistemáticas como Assunto
6.
Laryngoscope ; 131(11): E2792-E2801, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-33864634

RESUMO

OBJECTIVES/HYPOTHESIS: The purpose of this study was to characterize the clinical features, tremor variability, and factors related to octanoic acid (OA) treatment response in essential voice tremor (EVT). STUDY DESIGN: Prospective, double blind, placebo-controlled, crossover study with secondary analysis. METHODS: Clinical tremor features in 16 individuals with EVT were comprehensively assessed, and correlations with acoustic tremor severity were determined. Intrasubject and intersubject variability measures were analyzed from 18 repeated measures for each acoustic tremor variable. Clinical correlates of treatment response were evaluated, and cumulative effects over a 2-week period of OA drug dosing were assessed. RESULTS: Participants with EVT were 90% female with a mean age of 70.31 (±8.68) years at the time of testing. Neurologist-rated body tremor beyond the vocal tract region was present in 69% of participants, and multiple vocal tract regions contributed to the voice tremor. The mean frequency of amplitude tremor was 4.67 Hz (±0.88). Respiratory tremor was evident in 50% of participants. Participants experienced moderate voice-related disability as assessed on the Voice Handicap Index-10 (19.38, ±8.50), and increased speaking effort. Acoustic tremor severity was significantly associated with severity of tremor affecting vocal tract structures. Overall intrasubject consistency was strong (single measures intraclass correlation coefficient = 0.701, P < .01), with high intersubject variability. Acoustic tremor severity was significantly, positively associated with treatment response, and results suggested a cumulative OA benefit for magnitude of amplitude tremor. CONCLUSIONS: This study identified common clinical correlates of EVT and demonstrated positive associations between acoustic tremor severity, severity of affected vocal tract structures, and response to treatment. LEVEL OF EVIDENCE: 2 Laryngoscope, 131:E2792-E2801, 2021.


Assuntos
Caprilatos/uso terapêutico , Tremor Essencial/tratamento farmacológico , Distúrbios da Voz/fisiopatologia , Voz/efeitos dos fármacos , Idoso , Caprilatos/administração & dosagem , Estudos de Casos e Controles , Estudos Cross-Over , Método Duplo-Cego , Tremor Essencial/diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Fenótipo , Placebos/administração & dosagem , Estudos Prospectivos , Índice de Gravidade de Doença , Som/efeitos adversos , Resultado do Tratamento , Tremor/diagnóstico , Voz/fisiologia
7.
Integr Zool ; 16(4): 477-498, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33818895

RESUMO

The underwater soundscape is an important ecological element affecting numerous aquatic animals, in particular dolphins, which must identify salient cues from ambient ocean noise. In this study, temporal variations in the soundscape of Jiaotou Bay were monitored from February 2016 to January 2017, where a population of Indo-Pacific humpback dolphins (Sousa chinensis) has recently been a regular sighting. An autonomous acoustic recorder was deployed in shallow waters, and 1/3-octave band sound pressure levels (SPLs) were calculated with central frequencies ranging from 25 Hz to 40 kHz, then were grouped into 3 subdivided bands via cluster analysis. SPLs at each major band showed significant differences on a diel, fishing-related period, seasonal, and tidal phase scale. Anthropogenic noise generated by passing ships and underwater explosions were recorded in the study area. The fish and dolphin acoustic activities both exhibited diel and seasonal variations, but no tidal cycle patterns. A negative significant relationship between anthropogenic sound detection rates and dolphin detection rates were observed, and fish detection rates showed no effect on dolphin detection rates, indicating anthropogenic activity avoidance and no forced foraging in dolphins in the study area. The results provide fundamental insight into the acoustic dynamics of an important Indo-Pacific humpback dolphin habitat within a coastal area affected by a rapid increase in human activity, and demonstrate the need to protect animal habitat from anthropogenic noises.


Assuntos
Golfinhos/fisiologia , Peixes/fisiologia , Som/efeitos adversos , Acústica , Animais , Comportamento Animal , China , Monitoramento Ambiental/métodos , Explosões , Pesqueiros , Atividades Humanas , Navios , Vocalização Animal
8.
PLoS One ; 16(2): e0244599, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33626054

RESUMO

Soundscape ecology is an emerging field in both terrestrial and aquatic ecosystems, and provides a powerful approach for assessing habitat quality and the ecological response of sound-producing species to natural and anthropogenic perturbations. Little is known of how underwater soundscapes respond during and after severe episodic disturbances, such as hurricanes. This study addresses the impacts of Hurricane Irma on the coral reef soundscape at two spur-and-groove fore-reef sites within the Florida Keys USA, using passive acoustic data collected before and during the storm at Western Dry Rocks (WDR) and before, during and after the storm at Eastern Sambo (ESB). As the storm passed, the cumulative acoustic exposure near the seabed at these sites was comparable to a small vessel operating continuously overhead for 1-2 weeks. Before the storm, sound pressure levels (SPLs) showed a distinct pattern of low frequency diel variation and increased high frequency sound during crepuscular periods. The low frequency band was partitioned in two groups representative of soniferous reef fish, whereas the high frequency band represented snapping shrimp sound production. Daily daytime patterns in low-frequency sound production largely persisted in the weeks following the hurricane. Crepuscular sound production by snapping shrimp was maintained post-hurricane with only a small shift (~1.5dB) in the level of daytime vs nighttime sound production for this high frequency band. This study suggests that on short time scales, temporal patterns in the coral reef soundscape were relatively resilient to acoustic energy exposure during the storm, as well as changes in the benthic habitat and environmental conditions resulting from hurricane damage.


Assuntos
Acústica , Recifes de Corais , Animais , Crustáceos/fisiologia , Tempestades Ciclônicas , Ecossistema , Peixes/fisiologia , Florida , Som/efeitos adversos
9.
Curr Biol ; 31(7): 1555-1562.e4, 2021 04 12.
Artigo em Inglês | MEDLINE | ID: mdl-33567289

RESUMO

Geophysical exploration of the seabed is typically done through seismic surveys, using airgun arrays that produce intense, low-frequency-sound pulses1 that can be heard over hundreds of square kilometers, 24/7.2,3 Little is known about the effects of these sounds on free-ranging fish behavior.4-6 Effects reported range from subtle individual change in activity and swimming depth for captive fish7,8 to potential avoidance9 and changes in swimming velocity and diurnal activity patterns for free-swimming animals.10 However, the extent and duration of behavioral responses to seismic surveys remain largely unexplored for most fish species.4 In this study, we investigated the effect of a full-scale seismic survey on the movement behavior of free-swimming Atlantic cod (Gadus morhua). We found that cod did not leave the detection area more than expected during the experimental survey but that they left more quickly from 2 days to 2 weeks after the survey. Furthermore, during the exposure, cod decreased their activity, with time spent being "locally active" (moving small distances, showing high body acceleration) becoming shorter, and time spent being "inactive" (moving small distances, having low body acceleration) becoming longer. Additionally, diurnal activity cycles were disrupted with lower locally active peaks at dusk and dawn, periods when cod are known to actively feed.11,12 The combined effects of delayed deterrence and activity disruption indicate the potential for seismic surveys to affect energy budgets and to ultimately lead to population-level consequences.13.


Assuntos
Efeitos Antropogênicos , Gadus morhua , Som/efeitos adversos , Animais , Movimento
10.
Iran J Med Sci ; 46(1): 61-67, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33487793

RESUMO

Background: Misophonia is an unpleasant condition, in which the feeling of excessive anger is triggered by specific sounds. The main objective of the present study was to investigate the effectiveness of cognitive-behavioral therapy (CBT) on anger in female students with misophonia. Methods: A study based on a non-concurrent multiple baseline design was conducted in 2018 at the School of Education and Psychology, Shahid Chamran University of Ahvaz, Ahvaz, Iran. Three female students aged 20-22 years were recruited using the multi-stage random sampling method. The study was conducted in three stages, namely baseline, intervention, and follow-up sessions. The Novaco anger questionnaire was used during the baseline sessions, intervention sessions (sessions three, six, and eight), and six weeks follow-up (two, four, and six weeks after the last intervention session). Data were analyzed using visual analysis, reliability change index (RCI), and recovery percentage formula. Results: CBT reduced the feeling of anger after the intervention and follow-up sessions. The recovery percentage at the end of the intervention sessions were 43.82, 42.28, and 9.09 for the first, second, and third participants, respectively. Conclusion: The findings of the present study confirm the effectiveness of CBT in reducing the feeling of anger in female students with misophonia.


Assuntos
Terapia de Controle da Ira/normas , Ira , Terapia Cognitivo-Comportamental/normas , Som/efeitos adversos , Terapia de Controle da Ira/métodos , Terapia de Controle da Ira/estatística & dados numéricos , Terapia Cognitivo-Comportamental/métodos , Terapia Cognitivo-Comportamental/estatística & dados numéricos , Feminino , Humanos , Irã (Geográfico) , Reprodutibilidade dos Testes , Inquéritos e Questionários , Adulto Jovem
11.
Proc Natl Acad Sci U S A ; 117(50): 31603-31613, 2020 12 15.
Artigo em Inglês | MEDLINE | ID: mdl-33257581

RESUMO

We report on in vitro wound-healing and cell-growth studies under the influence of radio-frequency (rf) cell stimuli. These stimuli are supplied either by piezoactive surface acoustic waves (SAWs) or by microelectrode-generated electric fields, both at frequencies around 100 MHz. Employing live-cell imaging, we studied the time- and power-dependent healing of artificial wounds on a piezoelectric chip for different cell lines. If the cell stimulation is mediated by piezomechanical SAWs, we observe a pronounced, significant maximum of the cell-growth rate at a specific SAW amplitude, resulting in an increase of the wound-healing speed of up to 135 ± 85% as compared to an internal reference. In contrast, cells being stimulated only by electrical fields of the same magnitude as the ones exposed to SAWs exhibit no significant effect. In this study, we investigate this effect for different wavelengths, amplitude modulation of the applied electrical rf signal, and different wave modes. Furthermore, to obtain insight into the biological response to the stimulus, we also determined both the cell-proliferation rate and the cellular stress levels. While the proliferation rate is significantly increased for a wide power range, cell stress remains low and within the normal range. Our findings demonstrate that SAW-based vibrational cell stimulation bears the potential for an alternative method to conventional ultrasound treatment, overcoming some of its limitations.


Assuntos
Estimulação Acústica/métodos , Som/efeitos adversos , Vibração/uso terapêutico , Cicatrização/efeitos da radiação , Estimulação Acústica/efeitos adversos , Estimulação Acústica/instrumentação , Animais , Linhagem Celular , Linhagem Celular Tumoral , Movimento Celular/efeitos da radiação , Proliferação de Células/efeitos da radiação , Terapia Combinada/efeitos adversos , Terapia Combinada/instrumentação , Terapia Combinada/métodos , Cães , Eletrodos , Humanos , Células Madin Darby de Rim Canino , Estresse Oxidativo/efeitos dos fármacos , Espécies Reativas de Oxigênio
13.
J Mother Child ; 24(1): 33-38, 2020 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-33074179

RESUMO

OBJECTIVE: The aim of the study was to analyse the sound environment and the range of sound levels recorded in the delivery room immediately after the birth of a newborn. MATERIALS AND METHODS: The research method was open observation combined with recording measurements of the sound intensity levels. The material was collected by means of an observation questionnaire. The research was conducted in 11 maternity hospitals in Warsaw. A total of 304 vaginal labours were analysed. RESULTS: The average sound level in the delivery room after the birth of a newborn was 58.03 ± 7.66 dB, and the sound intensity ranged from 40.30 dB to 78.0 dB. Staff conversations were the most common sources of noise. A statistically significant relationship between the number of people in the delivery room and sound intensity was observed. The number of people positively correlated with the average sound level (R=0.520, p<0.001). CONCLUSIONS: Based on the tests, it was found that the average sound level in the delivery room exceeded the recommended standards. The noise was mainly caused by the activity of staff. The present study indicates the need for staff education and the use of noise reduction procedures.


Assuntos
Salas de Parto/normas , Exposição Ambiental/efeitos adversos , Monitoramento Ambiental/métodos , Ruído Ocupacional/efeitos adversos , Ruído/prevenção & controle , Feminino , Humanos , Recém-Nascido , Ruído/efeitos adversos , Gravidez , Som/efeitos adversos
14.
Hosp Pract (1995) ; 48(5): 258-265, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32729755

RESUMO

BACKGROUND/OBJECTIVE: Patients with aneurysmal subarachnoid hemorrhage (aSAH) may be at risk for complications related to excessive environmental noise. Our ICU utilizes a variety of universal interventions to minimize ambient noise levels, but patients with aSAH additionally have specific orders intended to further minimize physiologic stress and noise exposure. It is unknown whether such orders can have a supplementary reductive effect on noise exposure. METHODS: Sound levels were measured for at least three consecutive days in the rooms of 17 patients with aSAH and implemented 'subarachnoid precautions' orders. Sound levels were similarly recorded in the rooms of 11 geographically-proximate, critically-ill control patients without aSAH. RESULTS: Linear mixed models were used to assess the difference in measurements between groups. Observations were combined into fifteen-minute windows, then group means and their differences were calculated and plotted to help identify what times of the day had significant differences. aSAH patients consistently experienced lower sound levels than control patients, with a statistically significant difference (p < 0.05) in mean sound levels at 62 of 96 intervals throughout the day. Overall, the mean sound level for aSAH patients was always between 62-63dBA, while the mean sound level experienced by control patients ranged between 64-66dBA. CONCLUSIONS: Implementation of patient-specific orders can have a supplementary reductive effect on noise exposure for aSAH patients in an intensive care unit that already utilizes universal noise abatement interventions.


Assuntos
Estado Terminal/terapia , Unidades de Terapia Intensiva/normas , Ruído/efeitos adversos , Guias de Prática Clínica como Assunto , Som/efeitos adversos , Hemorragia Subaracnóidea/complicações , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
15.
Bioelectromagnetics ; 41(7): 500-510, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32726484

RESUMO

The hypothesis being tested was that the exposure of female workers to the electromagnetic field (EMF) emitted by an induction hob (IHb) meeting public exposure limitations (evaluated according to EN/IEC 62233) is also compliant with European Directive 2013/35/EU on workers' protection. The electric field induced in three female models in a realistic ergonomically comfortable posture near IHb was evaluated using numerical models of 25 kHz EMF sources (IHb covered by cooking vessels). It was found that, in analyzed ergonomically comfortable exposure situations, the electric field induced in the user's body may exceed public and workers' limits when the vessels do not match the dimensions of IHb's heating zone. This can even be the case when IHb complies with Conformité Européenne labeling requirements (i.e. EMF exposure falls below public limits 30 cm away from IHb edge). In the 36 exposure scenarios analyzed, statistically significant differences were found when the distances from IHb and vessel dimension, and the height and body mass index of models in exposure scenarios varied, but not between the use of models of pregnant and nonpregnant women. The use of IHb complying with European requirements on general public protection does not ensure that EMF exposure to workers complies with the relevant limits. Adequate protection measures need to address these occupational environmental hazards. © 2020 Bioelectromagnetics Society.


Assuntos
Campos Eletromagnéticos/efeitos adversos , Ergonomia , Campos Magnéticos , Exposição Ocupacional/análise , Exposição à Radiação/análise , Som/efeitos adversos , Feminino , Humanos , Modelos Biológicos , Exposição Ocupacional/efeitos adversos , Postura , Exposição à Radiação/efeitos adversos
16.
Int J Occup Med Environ Health ; 33(4): 389-408, 2020 Jun 16.
Artigo em Inglês | MEDLINE | ID: mdl-32406875

RESUMO

For several decades, low-frequency ultrasound (<100 kHz) has been widely used in industry, medicine, commerce, military service and the home. The objective of the study was to present the current state of the art on the harmful effects of low-frequency airborne ultrasound on people, especially in occupational settings. The scientific literature search was performed using accessible medical and other databases (WOS, BCI, CCC, DRCI, DIIDW, KJD, MEDLINE, RSCI, SCIELO and ZOOREC), and the obtained results were then hand-searched to eliminate non-relevant papers. This review includes papers published in 1948-2018. The potential effects of the low-frequency airborne ultrasound have been classified as auditory and non-auditory effects, including subjective, physiological, and thermal effects. In particular, already in the 1960-1970s, it was demonstrated that ultrasonic exposure, when sufficiently intense, appeared to result in a syndrome involving nausea, headache, vomiting, disturbance of coordination, dizziness, and fatigue, and might cause a temporary or permanent hearing impairment. However, since that time, not too much work has been done. Further studies are needed before any firm conclusions can be drawn about the auditory and non-auditory effects of low-frequency airborne ultrasound. Int J Occup Med Environ Health. 2020;33(4):389-408.


Assuntos
Som/efeitos adversos , Ondas Ultrassônicas/efeitos adversos , Perda Auditiva Provocada por Ruído , Humanos , Exposição Ocupacional/efeitos adversos
17.
PLoS One ; 15(2): e0229323, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32092095

RESUMO

Recent research using the Avon Longitudinal Study of Parents and Children (ALSPAC) demonstrated an association between maternal grandmother smoking in pregnancy and the autistic traits of impaired social communication and repetitive behaviour in granddaughters but not grandsons, but of paternal grandmother smoking and early development of myopia in the grandchild. Here we investigate whether grandmaternal smoking in pregnancy is associated with intolerance to loud sounds. ALSPAC collected information during the index pregnancy from the study parents on the smoking habits, social and other features of their own parents. Maternal report when the child was aged 6 and 13 included hating loud sounds; at age 11 the child was tested for volume preference for listening to music through headphones. Statistical analysis compared results for grandchildren in relation to whether a parent had been exposed in utero to maternal smoking, adjusted for their grandparents' social and demographic attributes. We hypothesised that there would be sex differences in the effects of grandmaternal prenatal smoking, based on previous intergenerational studies. For 6-year-old children maternal report of intolerance to loud noise was more likely in grandsons if the maternal grandmother had smoked [adjusted odds ratio (AOR) 1.27; 95% confidence interval (CI) 1.03,1.56; P = 0.025], but less likely in girls [AOR 0.82; 95%CI 0.63,1.07] Pinteraction <0.05. If the paternal grandmother had smoked the grandchildren were less likely to be intolerant, especially girls. The objective measure of choice of volume for music through headphones showed that grandsons of both maternal and paternal smoking grandmothers were less likely to choose high volumes compared with granddaughters (P<0.05). In line with our prior hypothesis of sex differences, we showed that grandsons were more intolerant of loud sounds than granddaughters particularly at age 6, and this was confirmed by objective measures at age 11.


Assuntos
Transtorno do Espectro Autista/etiologia , Doença Ambiental/etiologia , Avós , Relação entre Gerações , Som/efeitos adversos , Fumar Tabaco , Adolescente , Transtorno do Espectro Autista/epidemiologia , Criança , Inglaterra/epidemiologia , Doença Ambiental/epidemiologia , Feminino , Humanos , Estudos Longitudinais , Masculino , Ruído/efeitos adversos , Gravidez , Efeitos Tardios da Exposição Pré-Natal/epidemiologia , Efeitos Tardios da Exposição Pré-Natal/etiologia , Fatores de Risco , Comportamento Social , Fumar Tabaco/efeitos adversos , Fumar Tabaco/epidemiologia
18.
Cochrane Database Syst Rev ; 1: CD010333, 2020 01 27.
Artigo em Inglês | MEDLINE | ID: mdl-31986231

RESUMO

BACKGROUND: Infants in the neonatal intensive care unit (NICU) are subjected to stress, including sound of high intensity. The sound environment in the NICU is louder than most home or office environments and contains disturbing noises of short duration and at irregular intervals. There are competing auditory signals that frequently challenge preterm infants, staff and parents. The sound levels in NICUs often exceed the maximum acceptable level of 45 decibels (dB), recommended by the American Academy of Pediatrics. Hearing impairment is diagnosed in 2% to 10% of preterm infants versus 0.1% of the general paediatric population. Noise may cause apnoea, hypoxaemia, alternation in oxygen saturation, and increased oxygen consumption secondary to elevated heart and respiratory rates and may, therefore, decrease the amount of calories available for growth. Elevated levels of speech are needed to overcome the noisy environment in the NICU, thereby increasing the negative impacts on staff, newborns, and their families. High noise levels are associated with an increased rate of errors and accidents, leading to decreased performance among staff. The aim of interventions included in this review is to reduce sound levels to 45 dB or less. This can be achieved by lowering the sound levels in an entire unit, treating the infant in a section of a NICU, in a 'private' room, or in incubators in which the sound levels are controlled, or reducing the sound levels that reaches the individual infant by using earmuffs or earplugs. By lowering the sound levels that reach the neonate, the resulting stress on the cardiovascular, respiratory, neurological, and endocrine systems can be diminished, thereby promoting growth and reducing adverse neonatal outcomes. OBJECTIVES: Primary objective To determine the effects of sound reduction on growth and long-term neurodevelopmental outcomes of neonates. Secondary objectives 1. To evaluate the effects of sound reduction on short-term medical outcomes (bronchopulmonary dysplasia, intraventricular haemorrhage, periventricular leukomalacia, retinopathy of prematurity). 2. To evaluate the effects of sound reduction on sleep patterns at three months of age. 3. To evaluate the effects of sound reduction on staff performance. 4. To evaluate the effects of sound reduction in the neonatal intensive care unit (NICU) on parents' satisfaction with the care. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library), MEDLINE, EMBASE, CINAHL, abstracts from scientific meetings, clinical trials registries (clinicaltrials.gov; controlled-trials.com; and who.int/ictrp), Pediatric Academic Societies Annual meetings 2000 to 2014 (Abstracts2ViewTM), reference lists of identified trials, and reviews to November 2014. SELECTION CRITERIA: Preterm infants (< 32 weeks' postmenstrual age (PMA) or < 1500 g birth weight) cared for in the resuscitation area, during transport, or once admitted to a NICU or a stepdown unit. DATA COLLECTION AND ANALYSIS: We performed data collection and analyses according to the Cochrane Neonatal Review Group. MAIN RESULTS: One small, high quality study assessing the effects of silicone earplugs versus no earplugs qualified for inclusion. The original inclusion criteria in our protocol stipulated an age of < 48 hours at the time of initiating sound reduction. We made a deviation from our protocol and included this study in which some infants would have been > 48 hours old. There was no significant difference in weight at 34 weeks postmenstrual age (PMA): mean difference (MD) 111 g (95% confidence interval (CI) -151 to 374 g) (n = 23). There was no significant difference in weight at 18 to 22 months corrected age between the groups: MD 0.31 kg, 95% CI -1.53 to 2.16 kg (n = 14). There was a significant difference in Mental Developmental Index (Bayley II) favouring the silicone earplugs group at 18 to 22 months corrected age: MD 14.00, 95% CI 3.13 to 24.87 (n = 12), but not for Psychomotor Development Index (Bayley II) at 18 to 22 months corrected age: MD -2.16, 95% CI -18.44 to 14.12 (n =12). AUTHORS' CONCLUSIONS: To date, only 34 infants have been enrolled in a randomised controlled trial (RCT) testing the effectiveness of reducing sound levels that reach the infants' ears in the NICU. Based on the small sample size of this single trial, we cannot make any recommendations for clinical practice. Larger, well designed, conducted and reported trials are needed.


Assuntos
Recém-Nascido Prematuro/crescimento & desenvolvimento , Recém-Nascido de muito Baixo Peso/crescimento & desenvolvimento , Som/efeitos adversos , Estresse Fisiológico , Dispositivos de Proteção das Orelhas , Avaliação de Desempenho Profissional , Pessoal de Saúde/psicologia , Humanos , Recém-Nascido , Unidades de Terapia Intensiva Neonatal , Ruído , Ensaios Clínicos Controlados Aleatórios como Assunto
19.
Adv Exp Med Biol ; 1232: 113-119, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31893402

RESUMO

The prefrontal cortex (PFC) is sensitive to the stress exposure and involved in stress coping. And the effects of gum chewing on the stress have been studied using NIRS. However, when measuring NIRS on PFC during gum chewing, blood flows in shallow tissues (scalp, skin, muscle) might be affected. A NIRS used in the present study first, which has a short distance (1 cm) and the usual (3 cm) source-detector (S-D) regression, can allow eliminating shallow tissues effect of gum chewing. The aim of this study was to investigate the hypothesis that gum chewing activates the right prefrontal cortex (PFC) in stress coping against negative sounds (NS) from the International Affective Digitized Sounds-2 (IADS) as a mental stress task. NS showed activation in the right PFC. There was a significant difference between NS, and NS with Gum, where NS with Gum showed an increased PFC activity, increased alpha wave appearance rate, a higher value in heart rate level, and a higher VAS score indicating 'pleasant'. Gum chewing activated right PFC activity while exposed to negative sounds from IADS as a mental stress task.


Assuntos
Goma de Mascar , Mastigação , Som , Estresse Psicológico , Adaptação Psicológica , Adulto , Feminino , Humanos , Masculino , Córtex Pré-Frontal/fisiologia , Córtex Pré-Frontal/efeitos da radiação , Som/efeitos adversos , Estresse Psicológico/terapia , Adulto Jovem
20.
J Appl Anim Welf Sci ; 23(2): 193-208, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30806084

RESUMO

Drive hunts are a method to herd, capture and kill small cetaceans (whales and dolphins) in coastal waters of some countries including Japan and the Faroe Islands. In Japan, these methods are often associated with the acquisition of live dolphins for international marine parks and aquaria. During the hunts, dolphins are herded by a flotilla of fishing vessels and loud underwater noise created by fishermen banging hammers on metal poles. The prolonged and strenuous chase and use of sound barriers to herd, capture, and restrain the dolphins can result in acute stress and injury. The authors review physiological and behavioral data pertaining to chase, encirclement, and live capture of dolphins and draw comparisons between chase and capture data for marine and terrestrial species. This analysis raises substantial welfare concerns associated with the hunts and acquisition of dolphins from such capture operations. The authors assert that this data detailing the negative impacts of chase, herding and handling (capture) of small cetaceans renders these hunts inherently inhumane and should inform policy relating to the collection and management of dolphins in the wild.


Assuntos
Bem-Estar do Animal , Golfinhos/fisiologia , Animais , Golfinhos/lesões , Golfinhos/psicologia , Japão , Som/efeitos adversos , Estresse Fisiológico , Estresse Psicológico
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