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1.
BMC Oral Health ; 23(1): 929, 2023 11 27.
Artigo em Inglês | MEDLINE | ID: mdl-38008723

RESUMO

BACKGROUND: The injury of the inferior alveolar nerve (IAN) is one of the most serious complications of impacted mandibular third molars (IMTMs) extraction. The influence of the root orientation of IMTMs on IAN injury is still controversial. A deeper understanding of the risk factors of IAN injury conduces to better prevention of IAN injury. This study aims to explore whether root orientation is an independent risk factor of IAN injury during IMTMs extraction using the statistical strategy of propensity score matching (PSM). METHODS: This retrospective cohort study included 379 patients with 539 cases of high-risk IMTMs screened by panoramic radiography and cone beam computed tomography. The IAN injury incidence after extraction of different groups of IMTMs was analyzed using the chi-square test or Fisher's exact test. The correlation between third molar root orientation and impaction depth/contact degree with IAN was evaluated by the Lambda coefficient. Based on PSM for balancing confounding factors including age, sex, impaction depth, and contact degree, the effect of root orientation on the incidence of IAN injury was further analyzed using Fisher's exact test. RESULTS: There were significant group differences in IAN injury incidence in impaction depth, root orientation, and contact degree of root-IAC before PSM. Root orientation was correlated with impaction depth and contact degree of root-IAC. After PSM, there were 9 cases with IAN injury and 257 cases without IAN injury. There were significant group differences between the buccal and non-buccal groups after PSM, and the risk of IAN injury was higher when the root was located on the buccal side of IAC (OR = 8.448, RR = 8). CONCLUSIONS: Root orientation is an independent risk factor of IAN injury, and the risk is higher when the root is located on the buccal side of IAC. These findings could help better evaluate the risk of inferior alveolar nerve injury before the extraction of IMTMs.


Assuntos
Dente Impactado , Traumatismos do Nervo Trigêmeo , Humanos , Dente Serotino/cirurgia , Estudos Retrospectivos , Pontuação de Propensão , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia , Tomografia Computadorizada de Feixe Cônico/métodos , Dente Impactado/cirurgia , Nervo Mandibular , Mandíbula , Extração Dentária/efeitos adversos , Radiografia Panorâmica/métodos
2.
J Oral Maxillofac Surg ; 81(10): 1279-1285, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37463659

RESUMO

PURPOSE: Coronectomy is an operation to manage impacted third molars (M3s) considered at high risk for mandibular nerve injury but long-term outcomes are still lacking. The purpose of this study was to estimate the risk of late complications occurring within 10 years following lower M3 coronectomy. METHODS: The investigators designed a prospective cohort study and enrolled a sample of 94 patients treated with coronectomy of third mandibular molars at the Unit of Oral and Maxillofacial Surgery of the University of Bologna, from 2009 to 2012. This follow-up study included all of the patients from the original study who completed 10 years of follow-up. The primary outcome variables is postoperative late complication occurring between 5 and 10 years after coronectomy coded as present or absent. Late complications were defined as root exposure, nerve injury, pulpitis, periapical infection, and reoperation. The secondary outcome variable was probing pocket depth. Covariates examined were age, smoking and type of M3 impaction. Descriptive statistical analyses were performed. RESULTS: The inception cohort was composed of 94 subjects who had 116 coronectomies (k) completed. The study cohort was composed of subjects with 10 years of follow-up and included 48 subjects (k = 60) with a mean age of 28.99 ± 8.9 years. Between years 5 and 10 of follow-up, 2 subjects (4%) have complications; all root exposures diagnosed at years 8 or 9 after surgery. In another case root removal was required for orthodontics reason. No case of nerve injury to the inferior alveolar nerve occurred, and no periapical infection was observed around the residual roots. The mean 10-year probing pocket depth was 3.31 ± 0.92 mm (1,66-5,66 mm). There were too few complications to identify risk factors for late complications. CONCLUSIONS: Within all the limitations of this study, the results of this prospective study imply that coronectomy is a useful surgical technique for the treatment of M3s at high neurological risk, to avoid nerve injury to the inferior alveolar nerve. In addition, after coronectomy, retained roots did not develop late infection or periapical infection in the long term. However, in a few cases, removal of retained roots was required at 10 years, due to root migration in the oral cavity. The risk for late complications is uncommon, but persistent.


Assuntos
Dente Impactado , Traumatismos do Nervo Trigêmeo , Humanos , Adulto Jovem , Adulto , Seguimentos , Estudos Prospectivos , Dente Serotino/cirurgia , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia , Incidência , Coroa do Dente/cirurgia , Raiz Dentária/cirurgia , Complicações Pós-Operatórias/epidemiologia , Extração Dentária/efeitos adversos , Dente Impactado/cirurgia , Dente Impactado/complicações , Mandíbula/cirurgia , Nervo Mandibular
3.
PLoS One ; 17(9): e0275515, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36174089

RESUMO

INTRODUCTION: Maxillofacial trauma can be limited to superficial lacerations, abrasions, and facial bone fractures. The objective of this study was to determine the etiology, pattern, and predictors of soft tissue and bony injuries. MATERIALS AND METHODS: This study was conducted in the department of maxillofacial surgery Lady Reading hospital Pakistan from Jan 2019 to June 2021. The nonprobability consecutive sampling technique was used for the selection of patients. All patients were assessed clinically and radiologically. The neurosensory examination was done for any altered sensation, anesthesia, or paresthesia. Motor nerve function was also assessed clinically. Data were analyzed using SPSS version 26. The etiology and pattern of maxillofacial trauma were stratified among age and genders using the chi-square test to see effect modifiers. Tests for regression analysis were also applied. P≤0.05 was considered significant. RESULTS: A total of 253 patients meeting inclusion criteria were included in this study. The majority of these patients were males, 223 (88.1%), while only 30 (11.9%) were females. The mean age for the group was 25.4 ± 12.6 years. RTAs were the most common causes of trauma (63.6%) followed by assault (15.0%), falls (11.5%), FAIs (5.9%), and sports (0.4%). The most vulnerable skeletal part was the mandible (22.9%) followed by Zygoma (7.1%), significantly predicted by RTAs. Soft tissue laceration analysis showed a high frequency of multiple lacerations (38%) significantly predicted by FAIs. The frequency of trigeminal nerve injury was 5.5% (14 patients) and that of the facial nerve was 1.6% (4 patients). The strongest association of nerve injury was with firearm injury (47%), followed by road traffic accidents and sports injuries. CONCLUSION: Road traffic accident was the most common etiological factor and mandible fracture was commonly predicted by RTA. Trigeminal nerve injuries were common, frequency of nerve injuries was highly associated with mandible fracture and was predicted by FAI.


Assuntos
Armas de Fogo , Lacerações , Fraturas Mandibulares , Traumatismos Maxilofaciais , Traumatismos do Nervo Trigêmeo , Ferimentos por Arma de Fogo , Adolescente , Adulto , Causalidade , Criança , Feminino , Humanos , Masculino , Traumatismos Maxilofaciais/epidemiologia , Traumatismos Maxilofaciais/etiologia , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia , Adulto Jovem
4.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 57(3): 258-265, 2022 Mar 09.
Artigo em Chinês | MEDLINE | ID: mdl-35280003

RESUMO

Objective: To evaluate the risk factors of inferior alveolar nerve injury (IANI) after surgical removal of the mandibular third molars (M3) and present a new risk scoring system to predict the probability of IANI. Methods: Patients who underwent extraction of M3 in the Stomatology Hospital, Zhejiang University School of Medicine from April 2017 to December 2019 were involved. The investigators enrolled a sample composed of 949 mandibular third molars. Prediction model was used for univariate and multivariate analysis of gender, age, M3, inferior alveolar canal (IAC), and the contact between M3 and IAC, to assess the risk factors of IANI. Combined with the risk factors determined by the outcomes of prediction model, the risk scoring system was constructed. The diagnostic performance of each cut-off score was examined to conduct a risk stratification of IANI risk scores. The predictive ability and reliability of the model were evaluated. Results: In prediction model, twenty nine cases (4.4%, 29/664) experienced postoperative IANI. Number of root (P<0.01), depth of impaction (P<0.05), contact between M3 and IAC (P<0.01) and their contact position (P<0.05) were statistically significant as contributing risk factors of IANI. Specifically, the incidence of temporary IANI was higher in those who aged under 25 years (P<0.001), while female suffer more permanent injury (P<0.05). Based on the IANI risk scoring system, patients were stratified into low-risk, middle-risk and high-risk groups at cutoff scores of 3 and 4. The area under the receiver operator characteristic curve of the risk scoring system were 0.81 [95%CI (0.70-0.90), P=0.002] and 0.80 [95%CI (0.68-0.92), P=0.007] towards good discrimination. Conclusions: Age, gender, number of root, depth of impaction, and contact between M3 and IAC were risk factors of IANI. IANI risk scoring system might help in preoperative assessment, recognition of high-risk cases and decision-making to reduce IANI.


Assuntos
Dente Serotino , Traumatismos do Nervo Trigêmeo , Idoso , Feminino , Humanos , Mandíbula/cirurgia , Nervo Mandibular , Dente Serotino/cirurgia , Reprodutibilidade dos Testes , Fatores de Risco , Extração Dentária/efeitos adversos , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia
5.
Int J Oral Maxillofac Surg ; 51(2): 251-256, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34074573

RESUMO

An over-representation of women in dental implant-related inferior alveolar nerve injuries (IANIs) is recognized in the literature but has not been investigated. Therefore, a nationwide retrospective register study was conducted to analyse how IANIs compare with other implant-related complications (infection, implant malposition, lack of bone at implant site, mechanical damage, or failed osseointegration) separately in women and men. Financially compensated malpractice claims related to dental implant surgery were collected from the Finnish Patient Insurance Centre for the years 1997-2013, while the total number of nationally placed implants was ascertained from the implant register held by the Finnish Institute for Health and Welfare. In the 242 complications, the following were analysed: age of subject, absolute risk for complication, and aetiological factor of IANI. Statistical tests applied include Mann-Whitney U-test, Chi-squared test, and Fisher's exact test. Women sustaining IANI were more likely older than those having infection, mechanical damage, or failed osseointegration (P<0.05), while no significant differences emerged in men. Women were more likely at risk for IANI (P<0.01) or implant malposition (P<0.05) than men. The results support earlier propositions that women are more vulnerable than men to iatrogenic IANI.


Assuntos
Implantes Dentários , Traumatismos do Nervo Trigêmeo , Implantação Dentária Endóssea/efeitos adversos , Implantes Dentários/efeitos adversos , Falha de Restauração Dentária , Feminino , Humanos , Doença Iatrogênica/epidemiologia , Masculino , Nervo Mandibular , Osseointegração , Estudos Retrospectivos , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia
6.
Aust Dent J ; 66(2): 136-149, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33486775

RESUMO

BACKGROUND: Extraction of mandibular third molars (M3M) close to the inferior alveolar nerve (IAN) has a higher risk of neurological disturbance. This review aims to evaluate the evidence supporting the use of the coronectomy technique compared to complete extraction for such M3Ms. Case studies by a specialist oral and maxillofacial surgeon are included to illustrate clinical practice. METHODS: Three databases (Cochrane Library, Embase, PubMed) were searched (November 2020). Additional articles were sought by hand searching the reference list of included articles. All studies published in English comparing outcomes of coronectomy with complete extraction with at least 50 subjects and 6 months follow-up were included. RESULTS: Of the six included studies, five reported a lower rate of IAN disturbance after coronectomy compared with complete extraction. There were no reported cases of lingual nerve disturbance. Other outcomes of coronectomy such as pain, infection, alveolar osteitis were either similar or lower compared to complete extraction. There were high rates of root migration but low rates of exposure and reoperation. Follow-up protocols varied considerably. CONCLUSIONS: There is medium quality evidence to support the option of coronectomy for high risk M3M cases. Further studies to develop follow-up protocols to assist general dental practice is warranted.


Assuntos
Dente Impactado , Traumatismos do Nervo Trigêmeo , Humanos , Mandíbula/cirurgia , Nervo Mandibular , Dente Serotino/cirurgia , Coroa do Dente/cirurgia , Extração Dentária/efeitos adversos , Dente Impactado/cirurgia , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia
7.
J Oral Rehabil ; 47(10): 1212-1221, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32687637

RESUMO

BACKGROUND: Post-traumatic trigeminal neuropathy (PTN) is a disturbance of function or pathological change of the trigeminal nerve branches following trauma and has an important impact on patient's quality of life (QoL). OBJECTIVES: To provide diagnostic data on PTN and illustrate differences in aetiology, injured nerve, pain distribution, sensory profile and QoL between PTN subgroups. METHODS: 1331 patients with painful or non-painful PTN were retrospectively reviewed in two centres, extracting demographic data, time and cause of trauma, clinical findings including signs and symptoms, basic neurosensory testing, imaging modalities, treatments, and QoL or psychosocial assessment. RESULTS: More females were represented (70%) than males. The inferior alveolar nerve was most frequently damaged (60%) followed by the lingual nerve (28%). Wisdom teeth removal was considered the main cause (48%). Pain was reported in 63% of patients and pain frequency increased with age without clinically significant gender differences. Numbness was reported in 50% of PTN patients. Neurosensory testing showed larger affected dermatome involvement in persistent injuries, with no differences between the non-painful and painful PTN groups. Patient clustering indicated different sensory profile distributions when stratified according to aetiology or affected nerve branch. High interference with lifestyle was reported (78%), and patients suffering from painful PTN had worse QoL and psychosocial outcomes. CONCLUSION: Patients with painful PTN had different clinical profiles and lower QoL scores than those with non-painful PTN. Sensory profiles may provide important prognostic and therapeutic information; however, more research is needed to assess the clustering procedure and link these clusters to therapeutic guidelines.


Assuntos
Qualidade de Vida , Traumatismos do Nervo Trigêmeo , Feminino , Humanos , Masculino , Estudos Retrospectivos , Centros de Atenção Terciária , Traumatismos do Nervo Trigêmeo/complicações , Traumatismos do Nervo Trigêmeo/epidemiologia
8.
J Craniofac Surg ; 30(4): 1113-1117, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31166255

RESUMO

OBJECTIVES: To study the trigeminal nerve neuropathy prevalence after mandibular fractures and follow nerve recovery and to examine associations with clinical features. SUBJECTS: The files of 304 patients treated for 424 mandibular fractures in Hadassah Medical Center between 2001 and 2008 were analyzed. Twenty-five patients with paresthesia were examined by electro-diagnostic conduction test (quantitative sensory testing). RESULTS: The most common fracture sites were the symphysis (28.5%) and condyle (21.4%). A strong correlation between fracture severity and treatment modality was found. Nerve damage occurred in 13.4% of nondisplaced fractures and in 65.3% of >5 mm displaced fractures. Patients who were treated by open reduction internal fixation demonstrated the biggest difference in quantitative sensory testing values between the affected and nonaffected sides. C nerve fibers were the most damaged and least regenerated. There was correlation between damage perception and objective test results. CONCLUSIONS: There is a correlation between fracture type and displacement severity on neurologic deficit and prognosis. The objective neurosensory damage was manifested by higher nerve excitation threshold on the injured side. Patients should be informed on the prognosis of neurologic deficit according to fracture type.


Assuntos
Fraturas Mandibulares/complicações , Doenças do Nervo Trigêmeo/etiologia , Traumatismos do Nervo Trigêmeo/etiologia , Adulto , Eletrodiagnóstico , Feminino , Fixação Interna de Fraturas , Humanos , Escala de Gravidade do Ferimento , Israel/epidemiologia , Masculino , Fraturas Mandibulares/cirurgia , Pessoa de Meia-Idade , Redução Aberta , Doenças do Nervo Trigêmeo/diagnóstico , Doenças do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/diagnóstico , Traumatismos do Nervo Trigêmeo/epidemiologia , Escala Visual Analógica
9.
J Craniofac Surg ; 30(4): 1154-1162, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30839457

RESUMO

The present paper aims to evaluate the long-term incidence and severity of the neurosensory disturbance (NSD) of the inferior alveolar nerve following bilateral sagittal split osteotomy (BSSO) of the mandibular ramus performed with piezosurgery. A retrospective study on patients referred to the Maxillofacial Surgery and Dentistry Clinic of the University of Verona for orthognathic surgery between March 2013 and October 2015 was performed. Inclusion criteria were having undergone BSSO with piezosurgery and follow-up lasting at least 24 months. Exclusion criteria were history of surgical infection, osteosynthesis failure or re-do surgery. The extent of mandibular repositioning movements was retrieved and patients underwent 4 clinical neurosensory tests. Descriptive statistical analysis was performed. 52 patients met the inclusion criteria. Average follow-up was 40 months (range 24-75). 83% of the nerves examined have no or slightly altered sensitivity. Seventy-one percent of patients perceive a moderate to none discomfort and none describes the discomfort as serious (Visual Analogue Scale [VAS] >7). The extent of mandibular repositioning did not have significant influence on the development and severity of the NSD. Resulting data led the Authors to infer that using piezosurgery in BSSO, the severity of the NSD of inferior alveolar nerve is reduced, but the incidence of permanent nerve lesions remains unchanged, compared to historical controls.


Assuntos
Osteotomia Sagital do Ramo Mandibular , Piezocirurgia , Complicações Pós-Operatórias , Traumatismos do Nervo Trigêmeo , Humanos , Osteotomia Sagital do Ramo Mandibular/efeitos adversos , Osteotomia Sagital do Ramo Mandibular/métodos , Osteotomia Sagital do Ramo Mandibular/estatística & dados numéricos , Piezocirurgia/efeitos adversos , Piezocirurgia/estatística & dados numéricos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/fisiopatologia , Estudos Retrospectivos , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/fisiopatologia
10.
Br J Oral Maxillofac Surg ; 56(10): 946-951, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30424986

RESUMO

The osteotomy in a bilateral sagittal split ramus osteotomy (BSSRO) is made in close proximity to the inferior alveolar nerve (IAN), so direct damage to the nerve and irreversible neurosensory deficit may result. The aim of this study was to compare the incidence of injury to the nerve when a conventional osteotomy using an osteotome was made, with that after manual twist splitting. We retrospectively reviewed the casenotes of 769 consecutive patients who had bilateral SSRO either alone or with a simultaneous maxillary procedure by a single surgeon from May 2009 - October 2016. Patients were divided into two groups based on the technique used. Those in the first group had conventional split osteotomy using an osteotome and hammer for splitting (conventional group, 736 sides), and in those in the second group the manual twist technique was used (manual group, 802 sides). Patients who sustained Sunderland fifth degree injuries were identified from an existing record of nerve repairs. Fisher's exact test was used to evaluate the significance of the number of injuries to the nerve in each group. Conventional osteotomy and hammer-assisted SSRO resulted in 8/736 (1.1%) injuries to the IAN, whereas the manual twist splitting technique resulted in 1/802 injuries (0.1%). Our results confirm that the manual twist splitting technique significantly reduces the incidence of injury to the IAN, though the overall incidence was low.


Assuntos
Nervo Mandibular/cirurgia , Procedimentos Cirúrgicos Ortognáticos/efeitos adversos , Osteotomia Sagital do Ramo Mandibular/métodos , Traumatismos do Nervo Trigêmeo/etiologia , Adolescente , Adulto , Feminino , Humanos , Incidência , Masculino , Mandíbula/cirurgia , Procedimentos Cirúrgicos Ortognáticos/métodos , Osteotomia Sagital do Ramo Mandibular/efeitos adversos , Estudos Retrospectivos , Traumatismos do Nervo Trigêmeo/epidemiologia , Adulto Jovem
11.
G Chir ; 39(5): 276-283, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30368265

RESUMO

INTRODUCTION: The aim of this study is to perform a review of the English-language international literature concerning thyroid surgery performed through the transoral vestibular approach, to evaluate its flessibility and safety in terms of complications. MATERIALS AND METHOD: The review was carried out on 17 studies of 17 different Authors. The following variables were taken into consideration: first Author's name, nationality, year of publication, number of cases, hospital stay, conversion rate, type of surgical approach, total number of total thyroidectomies and loboisthmectomies, operative time range, intraoperative blood loss range, number and percentage of complications. RESULTS: 736 procedures were performed: 289 total thyroidectomies and 447 loboisthmectomies. Surgical approach was trivestibular in 15 cases and combined (oro-vestibular) in 2 cases. The operative time varies from 43 minutes for a loboisthmectomy to 345 for a total thyroidectomy. Intraoperative blood loss ranges from 3 to 300 ml. Ten cases were converted into open surgery. The hospital stay varies from 1 to 10 days. Complications were: transient recurrent laryngeal nerve palsy in 34 cases, permanent in 2 cases; transient hypoparathyroidism in 62 cases. One case of postoperative bleeding, 22 postoperative seroma, 20 cases of mental nerve injury, 8 cases of operative wound infection. CONCLUSIONS: Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a new surgical method, the use of which exclusively meets the aesthetic needs of some patients. Its specific complication is the injury of the mental nerves. Further studies, however, seem to be necessary, on numerically broader cases, to ascertain the real validity of the method.


Assuntos
Cirurgia Endoscópica por Orifício Natural/métodos , Tireoidectomia/métodos , Cirurgia Vídeoassistida , Perda Sanguínea Cirúrgica , Conversão para Cirurgia Aberta/estatística & dados numéricos , Humanos , Hipoparatireoidismo/epidemiologia , Hipoparatireoidismo/etiologia , Tempo de Internação/estatística & dados numéricos , Boca , Cirurgia Endoscópica por Orifício Natural/efeitos adversos , Cirurgia Endoscópica por Orifício Natural/estatística & dados numéricos , Duração da Cirurgia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Hemorragia Pós-Operatória/epidemiologia , Hemorragia Pós-Operatória/etiologia , Procedimentos Cirúrgicos Robóticos/efeitos adversos , Procedimentos Cirúrgicos Robóticos/métodos , Procedimentos Cirúrgicos Robóticos/estatística & dados numéricos , Infecção da Ferida Cirúrgica/epidemiologia , Tireoidectomia/efeitos adversos , Tireoidectomia/estatística & dados numéricos , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia , Cirurgia Vídeoassistida/efeitos adversos , Cirurgia Vídeoassistida/estatística & dados numéricos , Paralisia das Pregas Vocais/epidemiologia , Paralisia das Pregas Vocais/etiologia
12.
Int J Oral Maxillofac Surg ; 47(6): 789-793, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29523381

RESUMO

With the growing demand for dental work, trigeminal nerve injuries are increasingly common. This retrospective cohort study examined 53 cases of iatrogenic trigeminal nerve injury seen at the Department of Oral and Maxillofacial Surgery, University Hospitals of Leuven between 2013 and 2014 (0.6% among 8845 new patient visits). Patient records were screened for post-traumatic trigeminal nerve neuropathy caused by nerve injury incurred during implant surgery, endodontic treatment, local anaesthesia, tooth extraction, or specifically third molar removal. The patients ranged in age from 15 to 80years (mean age 42.1years) and 68% were female. The referral delay ranged from 1day to 6.5years (average 10months). The inferior alveolar nerve (IAN) was most frequently injured (28 cases), followed by the lingual nerve (LN) (21 cases). Most nerve injuries were caused during third molar removal (24 cases), followed by implant placement (nine cases) and local anaesthesia injuries (nine cases). Pain symptoms were experienced by 54% of patients suffering IAN injury, compared to 10% of patients with LN injury. Persistent neurosensory disturbances were identified in 60% of patients. While prevention remains the key issue, timely referral seems to be a critical factor for the successful treatment of post-traumatic neuropathy.


Assuntos
Assistência Odontológica/efeitos adversos , Traumatismos do Nervo Trigêmeo/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Bélgica/epidemiologia , Feminino , Humanos , Doença Iatrogênica , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco
13.
Gerodontology ; 35(2): 117-122, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29460459

RESUMO

OBJECTIVE: To determine the prevalence and the clinical features of patients with neuropathic pain and sensory alterations after dental implant placement. BACKGROUND: Literature is very scarce concerning the prevalence of neuropathic pain after dental implant placement. PATIENTS AND METHODS: A retrospective cohort study was made in patients submitted to dental implant placement in the Dental Hospital of the University of Barcelona. A descriptive analysis of the data was made, and the 95% confidence intervals (95% CI) were calculated for the prevalences. RESULTS: The study sample was composed of 1156 subjects of whom, 1012 patients (3743 dental implants) met the study inclusion criteria. Four hundred and seventeen patients (41.2%) were male and 595 (58.8%) were female, with a mean age of 60.7 years (range 16-90 years). Three patients were diagnosed as having painful post-traumatic trigeminal neuropathy (PPTN), which corresponds to a prevalence of 0.3% (95% CI: 0%-0.6%). Additionally, 5 patients (0.5%; 95% CI: 0%-1.07%) presented trigeminal neuropathy without pain (TNWP). The combined prevalence of both disorders was 0.8% (95% CI: 0.02%-1.3%). All patients with PPTN and TNWP were 60 years old or older, with a total combined prevalence of 1.48% (95% CI: 0.46%-2.5%) in this age group. Additionally, the prevalence in this age group for women was 1.85% (95%CI: 0.38%-3.31%). CONCLUSIONS: Neuropathic pain after dental implant placement is very infrequent (0.3%) in a University Oral Surgery department. However, the presence of trigeminal neuropathies can be slightly higher and can affect up to 0.5% of patients. Older female patients seem to be more prone to this rare and disabling complication.


Assuntos
Implantação Dentária Endóssea/efeitos adversos , Neuralgia/etiologia , Transtornos de Sensação/etiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neuralgia/epidemiologia , Prevalência , Estudos Retrospectivos , Transtornos de Sensação/epidemiologia , Espanha/epidemiologia , Cirurgia Bucal/educação , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia , Universidades , Adulto Jovem
14.
J Neurosurg ; 128(2): 362-372, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-28338439

RESUMO

OBJECTIVE Parasellar meningiomas tend to invade the suprasellar, cavernous sinus, and petroclival regions, encroaching on adjacent neurovascular structures. As such, they prove difficult to safely and completely resect. Stereotactic radiosurgery (SRS) has played a central role in the treatment of parasellar meningiomas. Evaluation of tumor control rates at this location using simplified single-dimension measurements may prove misleading. The authors report the influence of SRS treatment parameters and the timing and volumetric changes of benign WHO Grade I parasellar meningiomas after SRS on long-term outcome. METHODS Patients with WHO Grade I parasellar meningiomas treated with single-session SRS and a minimum of 6 months of follow-up were selected. A total of 189 patients (22.2% males, n = 42) form the cohort. The median patient age was 54 years (range 19-88 years). SRS was performed as a primary upfront treatment for 44.4% (n = 84) of patients. Most (41.8%, n = 79) patients had undergone 1 resection prior to SRS. The median tumor volume at the time of SRS was 5.6 cm3 (0.2-54.8 cm3). The median margin dose was 14 Gy (range 5-35 Gy). The volumes of the parasellar meningioma were determined on follow-up scans, computed by segmenting the meningioma on a slice-by-slice basis with numerical integration using the trapezoidal rule. RESULTS The median follow-up was 71 months (range 6-298 months). Tumor volume control was achieved in 91.5% (n = 173). Tumor progression was documented in 8.5% (n = 16), equally divided among infield recurrences (4.2%, n = 8) and out-of-field recurrences (4.2%, n = 8). Post-SRS, new or worsening CN deficits were observed in 54 instances, of which 19 involved trigeminal nerve dysfunction and were 18 related to optic nerve dysfunction. Of these, 90.7% (n = 49) were due to tumor progression and only 9.3% (n = 5) were attributable to SRS. Overall, this translates to a 2.64% (n = 5/189) incidence of direct SRS-related complications. These patients were treated with repeat SRS (6.3%, n = 12), repeat resection (2.1%, n = 4), or both (3.2%, n = 6). For patients treated with a margin dose ≥ 16 Gy, the 2-, 4-, 6-, 8-, 10-, 12-, and 15-year actuarial progression-free survival rates are 100%, 100%, 95.7%, 95.7%, 95.7%, 95.7%, and 95.7%, respectively. Patients treated with a margin dose < 16 Gy, had 2-, 4-, 6-, 8-, 10-, 12-, and 15-year actuarial progression-free survival rates of 99.4%, 97.7%, 95.1%, 88.1%, 82.1%, 79.4%, and 79.4%, respectively. This difference was deemed statistically significant (p = 0.043). Reviewing the volumetric patient-specific measurements, the early follow-up volumetric measurements (at the 3-year follow-up) reliably predicted long-term volume changes and tumor volume control (at the 10-year follow-up) (p = 0.029). CONCLUSIONS SRS is a durable and minimally invasive treatment modality for benign parasellar meningiomas. SRS offers high rates of growth control with a low incidence of neurological deficits compared with other treatment modalities for meningiomas in this region. Volumetric regression or stability during short-term follow-up of 3 years after SRS was shown to be predictive of long-term tumor control.


Assuntos
Meningioma/cirurgia , Procedimentos Neurocirúrgicos/métodos , Radiocirurgia/métodos , Sela Túrcica/cirurgia , Neoplasias da Base do Crânio/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Estimativa de Kaplan-Meier , Masculino , Meningioma/patologia , Pessoa de Meia-Idade , Recidiva Local de Neoplasia , Traumatismos do Nervo Óptico/epidemiologia , Traumatismos do Nervo Óptico/etiologia , Complicações Pós-Operatórias/epidemiologia , Intervalo Livre de Progressão , Reoperação , Estudos Retrospectivos , Sela Túrcica/patologia , Neoplasias da Base do Crânio/patologia , Resultado do Tratamento , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia , Adulto Jovem
15.
J Am Dent Assoc ; 148(8): 575-583, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28532570

RESUMO

BACKGROUND: Clinicians generally use panoramic radiographic (PR) images to assess the proximity of the mandibular third molar to the inferior alveolar nerve (IAN). However, in cases in which a patient needs to undergo a third-molar extraction, many clinicians also assess computed tomographic (CT) images to prevent nerve damage. TYPES OF STUDIES REVIEWED: Two of the authors independently searched MEDLINE (through PubMed), Cochrane Library, Scopus, and Ovid. The authors included randomized or nonrandomized longitudinal studies whose investigators had compared the number of IAN injuries after third-molar extraction in patients who had undergone preoperative CT with patients who had undergone only PR. RESULTS: The authors analyzed the full text of 26 of the 745 articles they initially selected. They included 6 studies in the meta-analysis. Four of the studies had a high risk of bias, and the investigators of only 1 study had used blinding with the patients. The authors observed no statistically significant differences between groups related to the total number of nerve injuries (risk ratio, 0.96; 95% confidence interval, 0.50 to 1.85; P = .91). The prognosis of the injuries was similar for both groups. CONCLUSIONS AND PRACTICAL IMPLICATIONS: Although having preoperative CT images might be useful for clinicians in terms of diagnosing and extracting mandibular third molars, having these CT images does not reduce patients' risk of experiencing IAN injuries nor does it affect their prognosis.


Assuntos
Dente Serotino/diagnóstico por imagem , Radiografia Dentária , Tomografia Computadorizada por Raios X , Extração Dentária/efeitos adversos , Traumatismos do Nervo Trigêmeo/prevenção & controle , Humanos , Nervo Mandibular/diagnóstico por imagem , Dente Serotino/cirurgia , Radiografia Panorâmica , Extração Dentária/métodos , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/etiologia
16.
Gen Dent ; 65(2): 34-41, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28253180

RESUMO

Many forms of dental treatment have the potential to cause injury to the oral branches of the trigeminal nerve, including local anesthetic injections, root canal therapy, implant insertion, bone grafting, and dentoalveolar surgery. Based on the records of a referral center with more than 30 years' experience in managing 3200 of these injuries, this article reviews etiology and prevention; suggests criteria for referral of patients; and discusses treatment for the various types of injury and the results of such treatment.


Assuntos
Assistência Odontológica/efeitos adversos , Traumatismos do Nervo Trigêmeo/etiologia , Anestesia Dentária/efeitos adversos , Transplante Ósseo/efeitos adversos , Implantação Dentária/efeitos adversos , Humanos , Procedimentos Cirúrgicos Bucais/efeitos adversos , Tratamento do Canal Radicular/efeitos adversos , Traumatismos do Nervo Trigêmeo/epidemiologia , Traumatismos do Nervo Trigêmeo/prevenção & controle
17.
Implant Dent ; 25(5): 638-45, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27540843

RESUMO

BACKGROUND: Dental implant-related iatrogenic trigeminal nerve (TG) injuries are proportionally increasing with dental implant surgery. This study, which is presented in greater detail over a series of articles, assessed the experience of implant-related TG nerve injuries among UK dentists. Incidence and cause of inferior alveolar nerve (IAN), mental nerve (MN), and lingual nerve (LN) injuries, together with preoperative assessment and the consent process, are presented in this article. METHODS: A survey was distributed among 405 dentists attending an Association of Dental Implantology congress in the United Kingdom, of which 187 completed the survey. RESULTS: Most responding dentists were full-time general practitioners. Implant dentistry training was predominately through industry-organized courses. Eighty dentists encountered implant-related IAN injuries, whereas 8 encountered LN injuries. Inaccurate radiological identification of the IAN/MN and their anatomical variations (48%) were seen to be the most frequent cause of TG injuries. Disclosure of the relative risk and benefits of alternative implant treatment strategies as part of the informed consent process was not deemed to be essential by 47 (25%) of the participants. CONCLUSION: Inadequate radiological assessment was the most common cause of TG nerve injury. The use of small field of view cone beam computer tomography (CBCT) is therefore recommended when placing implants in the posterior mandible. Implant surgeons should acquire evidence-based skills in the prevention, diagnosis, and management of TG nerve injury as well as specific training on justification and interpretation of CBCT scans.


Assuntos
Implantação Dentária/efeitos adversos , Odontólogos/estatística & dados numéricos , Traumatismos do Nervo Trigêmeo/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Atitude do Pessoal de Saúde , Humanos , Incidência , Pessoa de Meia-Idade , Fatores de Risco , Inquéritos e Questionários , Traumatismos do Nervo Trigêmeo/epidemiologia , Reino Unido/epidemiologia
18.
Dentomaxillofac Radiol ; 45(4): 20150226, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26943178

RESUMO

OBJECTIVES: To assess radiographic methods and diagnostically sufficient images used before removal of mandibular third molars among randomly selected general dental clinics. Furthermore, to assess factors predisposing for an additional radiographic examination. METHODS: 2 observers visited 18 randomly selected clinics in Denmark and studied patient files, including radiographs of patients who had their mandibular third molar(s) removed. The radiographic unit and type of receptor were registered. A diagnostically sufficient image was defined as the whole tooth and mandibular canal were displayed in the radiograph (yes/no). Overprojection between the tooth and mandibular canal (yes/no) and patient-reported inferior alveolar nerve sensory disturbances (yes/no) were recorded. Regression analyses tested if overprojection between the third molar and the mandibular canal and an insufficient intraoral image predisposed for additional radiographic examination(s). RESULTS: 1500 mandibular third molars had been removed; 1090 had intraoral, 468 had panoramic and 67 had CBCT examination. 1000 teeth were removed after an intraoral examination alone, 433 after panoramic examination and 67 after CBCT examination. 90 teeth had an additional examination after intraoral. Overprojection between the tooth and mandibular canal was a significant factor (p < 0.001, odds ratio = 3.56) for an additional examination. 63.7% of the intraoral images were sufficient and 36.3% were insufficient, with no significant difference between images performed with phosphor plates and solid-state sensors (p = 0.6). An insufficient image predisposed for an additional examination (p = 0.008, odds ratio = 1.8) but was only performed in 11% of the cases. CONCLUSIONS: Most mandibular third molars were removed based on an intraoral examination although 36.3% were insufficient.


Assuntos
Mandíbula/diagnóstico por imagem , Dente Serotino/diagnóstico por imagem , Extração Dentária , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Tomografia Computadorizada de Feixe Cônico/estatística & dados numéricos , Dinamarca/epidemiologia , Clínicas Odontológicas/estatística & dados numéricos , Estudos Epidemiológicos , Feminino , Odontologia Geral/estatística & dados numéricos , Humanos , Masculino , Mandíbula/cirurgia , Nervo Mandibular/diagnóstico por imagem , Pessoa de Meia-Idade , Dente Serotino/cirurgia , Intensificação de Imagem Radiográfica/métodos , Radiografia Interproximal/estatística & dados numéricos , Radiografia Dentária Digital/estatística & dados numéricos , Radiografia Panorâmica/estatística & dados numéricos , Estudos Retrospectivos , Extração Dentária/estatística & dados numéricos , Traumatismos do Nervo Trigêmeo/epidemiologia , Ecrans Intensificadores para Raios X/estatística & dados numéricos , Adulto Jovem
19.
Int J Oral Maxillofac Surg ; 45(5): 571-4, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26867667

RESUMO

The treatment dilemma provided by asymptomatic third molars in mandibular angle fractures remains controversial. This prospective randomized controlled trial was undertaken to determine whether there is an advantage to extraction or retention of the third molar whilst repairing a mandibular angle fracture. Sixty-four patients were allocated randomly to the two treatment groups. All underwent open reduction and internal fixation (ORIF) with standard postoperative care. The primary outcome measure was uncomplicated fracture healing. Secondary measures were surgical duration, malocclusion, wound healing, nerve injury, and return to theatre. All patients had uncomplicated fracture healing. The incidence of nerve injury was 16% for the retention group compared with 39% for the removal group (P=0.038). The average operating time for ORIF and third molar retention cases was 58.5min and for ORIF and third molar removal cases was 66.3min (P=0.26). There was no statistically significant difference between groups for wound healing, occlusion outcomes, or return to theatre. Given the additional risk of nerve injury and the additional operating time required for removal of a third molar, in the absence of an absolute indicator for removal of the third molar, it appears justifiable to advise retaining the tooth in the line of a mandibular angle fracture.


Assuntos
Técnicas de Fixação da Arcada Osseodentária , Fraturas Mandibulares/cirurgia , Dente Serotino/cirurgia , Adolescente , Adulto , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/epidemiologia , Estudos Prospectivos , Extração Dentária , Resultado do Tratamento , Traumatismos do Nervo Trigêmeo/epidemiologia
20.
Artigo em Inglês | MEDLINE | ID: mdl-26337212

RESUMO

OBJECTIVE: To monitor the long-term morbidity of retained roots up to 5 years following lower third molars coronectomy with close proximity to the inferior alveolar nerve (IAN). STUDY DESIGN: A prospective study on long-term morbidities after lower third molar coronectomy. RESULTS: This study included 612 lower third molar coronectomies in 458 patients. The prevalence of IAN injury was 0.16% (1/612) and was temporary. Long-term postoperative infection occurred in 1 case at 6 months following surgery and another at 12 months. No infection was found after 12 months. The incidence rates of pain at 6 months, 12 months, 24 months after surgery were 0.50% (3/596), 0.38% (2/529), 0.49% (2/411), respectively. Root exposure was noted in 2.3% of cases (14/612). Reoperation to remove the exposed root did not cause any IAN deficit. CONCLUSIONS: Lower third molar coronectomy is safe in the long term.


Assuntos
Dente Serotino/cirurgia , Complicações Pós-Operatórias/epidemiologia , Coroa do Dente/cirurgia , Dente Impactado/cirurgia , Adulto , Feminino , Humanos , Incidência , Masculino , Medição da Dor , Dor Pós-Operatória/epidemiologia , Estudos Prospectivos , Radiografia Panorâmica , Reoperação , Infecção da Ferida Cirúrgica/epidemiologia , Migração de Dente/epidemiologia , Raiz Dentária/patologia , Raiz Dentária/cirurgia , Resultado do Tratamento , Traumatismos do Nervo Trigêmeo/epidemiologia
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