The Pheochromocytoma/Paraganglioma syndrome: an overview on mechanisms, diagnosis and management
Int. braz. j. urol
; 49(3): 307-319, may-June 2023. tab, graf
Article
em En
|
LILACS-Express
| LILACS
| ID: biblio-1440249
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Pheochromocytomas/paragangliomas (PPGL) are rare, metastatic, and potentially fatal neuroendocrine tumors, often neglected because they present symptoms similar to other prevailing clinical conditions such panic syndrome, thyrotoxicosis, anxiety, hypoglycemia, etc., delaying diagnosis and treatment. The rate of diagnosis of PPGL has been increasing with the improvement in the measurement of catecholamine metabolites and the expanding availability of imaging procedures. Its essential genetic nature has been extensively investigated, comprising more than 20 genes currently related to PPGL and more new genes will probably be revealed. This overview will shed some light on the clinical, laboratory, topographical, genetic diagnosis, and management of PPGL.
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Base de dados:
LILACS
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article