Alert for the high prevalence of vitamin D deficiency in adolescents in a large Brazilian sample
J. pediatr. (Rio J.)
; 100(4): 360-366, July-Aug. 2024. tab, graf
Article
em En
|
LILACS-Express
| LILACS
| ID: biblio-1564754
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Objective:
To estimate the prevalence of vitamin D deficiency and severe deficiency in children and adolescents, in a large Brazilian sample.Methodology:
Results of 413,988 25(OH)D measurements in children and adolescents aged 0 to 18 years collected between 01/2014 and 10/2018 were obtained from the database of a Clinical Laboratory. In this population, 25 hydroxyvitamin D concentrations below 20 ng/mL are considered deficient, and below 12 ng/mL as severe deficiency. All measurements were performed by immunoassay and the results were distributed by gender, age group, seasonality, and latitude.Results:
The mean of 25(OH)D levels was 29.2 ng/mL with a standard deviation of 9.2 ng/mL. Of the total samples, 0.8% had a concentration < 12 ng/mL, and 12.5% of the samples had a concentration < 20 ng/mL, with a higher prevalence in females. Children under 2 years of age had the lowest prevalence. The effects of latitude and seasonality were quite evident. In samples of female adolescents from the southern region in winter, 36% of vitamin D deficiency and 5% of severe deficiency were found.Conclusion:
In this large number of measurements of 25(OH)D in children and adolescents, 12.5% had a deficiency and 0.8% had severe deficiency. A greater deficiency was observed among adolescents, especially females, which raises questions about the need for supplementation during this period of life.
Texto completo:
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Base de dados:
LILACS
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article