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Antimicrobial activity and substantivity of Uncaria tomentosa in infected root canal dentin
Herrera, Daniel Rodrigo; Durand-Ramirez, Jorge Enrique; Falcão, Amanda; Silva, Emmanuel João Leal Nogueira da; Santos, Elizabete Brasil dos; Gomes, Brenda Paula Figueiredo de Almeida.
Afiliação
  • Herrera, Daniel Rodrigo; Universidade Estadual de Campinas. Department of Restorative Dentistry. Endodontic Division. Piracicaba. BR
  • Durand-Ramirez, Jorge Enrique; Universidade Estadual de Campinas. Department of Restorative Dentistry. Endodontic Division. Piracicaba. BR
  • Falcão, Amanda; Universidade Estadual de Campinas. Department of Restorative Dentistry. Endodontic Division. Piracicaba. BR
  • Silva, Emmanuel João Leal Nogueira da; Universidade do Grande Rio. Health and Science Center. Department of Endodontics. Rio de Janeiro. BR
  • Santos, Elizabete Brasil dos; Universidade Estadual de Ponta Grossa. Department of Dentistry. Ponta Grossa. BR
  • Gomes, Brenda Paula Figueiredo de Almeida; Universidade Estadual de Campinas. Department of Restorative Dentistry. Endodontic Division. Piracicaba. BR
Braz. oral res. (Online) ; 30(1): e61, 2016. tab, graf
Artigo em Inglês | LILACS | ID: biblio-952067
Biblioteca responsável: BR1.1
ABSTRACT
Abstract The aim of this study was to analyze the antimicrobial activity and substantivity of Uncaria tomentosa Willd DC (cat's claw, CC) in root dentin contaminated with Enterococcus faecalis. Forty-eight human premolars were contaminated with E. faecalis (ATCC 29212) and randomly divided into four groups according to the irrigant used during chemomechanical preparation (CMP) CC group 2% CC gel; CHX group 2% chlorhexidine digluconate gel (CHX); NaOCl group 5.25% sodium hypochlorite (NaOCl); and SS group sterile saline (SS). Microbiological samples were collected before (S1) and after (S2) CMP and after 7 days (S3). Colony-forming units (CFU/mL) at the different sampling times and comparisons among the groups were statistically analyzed by Wilcoxon and Kruskal-Wallis tests (p < 0.05). Significant bacterial reduction was achieved in all groups after CMP (p < 0.05). Results show no significant difference between S3 and S2 (p > 0.05) in the CC and CHX groups. Bacterial load was higher in S3 than in S2 samples (p < 0.05) in the NaOCl and SS groups. Our results suggest antibacterial effect of 2% CC gel against E. faecalis in infected dentin, in addition to antibacterial substantivity of 2% CC and 2% CHX up to 7 days.
Assuntos

Texto completo: Disponível Base de dados: LILACS Assunto: Enterococcus faecalis / Unha-de-Gato / Cavidade Pulpar / Dentina / Anti-Infecciosos Tipo de estudo: Ensaio clínico controlado / Estudo de avaliação Limite: Humanos Idioma: Inglês Revista: Braz. oral res. (Online) Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: Disponível Base de dados: LILACS Assunto: Enterococcus faecalis / Unha-de-Gato / Cavidade Pulpar / Dentina / Anti-Infecciosos Tipo de estudo: Ensaio clínico controlado / Estudo de avaliação Limite: Humanos Idioma: Inglês Revista: Braz. oral res. (Online) Ano de publicação: 2016 Tipo de documento: Artigo