Assessment of the rapid test based on an immunochromatography technique for detecting anti-Treponema pallidum antibodies
Rev. Inst. Med. Trop. Säo Paulo
; Rev. Inst. Med. Trop. Säo Paulo;45(6): 319-322, Nov.-Dec. 2003. tab
Article
em En
| LILACS
| ID: lil-353982
Biblioteca responsável:
BR1.1
RESUMO
A rapid test based on an immunochromatography assay - DetermineÕ Syphilis TP (Abbott Lab.) for detecting specific antibodies to Treponema pallidum was evaluated against serum samples from patients with clinical, epidemiological and serological diagnosis of syphilis, patients with sexually transmitted disease other than syphilis, and individuals with negative serology for syphilis. The DetermineÕ test presented the sensitivity of 93.6 percent, specificity of 92.5 percent, and positive predictive value and negative predictive value of 95.2 percent and 93.7 percent, respectively. One serum sample from patient with recent latent syphilis showed a prozone reaction. DetermineÕ is a rapid assay, highly specific and easy to perform. This technique obviates the need of equipment and its diagnostic features demonstrate that it may be applicable as an alternative assay for syphilis screening under some emergency conditions or for patients living in remote localities.
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Treponema pallidum
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Testes Imunológicos
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Sífilis
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Cromatografia
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Anticorpos Antibacterianos
Idioma:
En
Ano de publicação:
2003
Tipo de documento:
Article