Characterization of a gelatin/chitosan/hyaluronan scaffold-polymer
Electron. j. biotechnol
; 13(5): 20-21, Sept. 2010. ilus, tab
Article
em En
| LILACS
| ID: lil-591902
Biblioteca responsável:
CL1.1
ABSTRACT
Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties.
Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Quitosana
/
Gelatina
/
Ácido Hialurônico
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article
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Project document