Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
Braz. j. microbiol
; 44(4): 1035-1041, Oct.-Dec. 2013. tab
Artigo
em Inglês
| LILACS
| ID: lil-705291
Biblioteca responsável:
BR1.1
ABSTRACT
Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
Texto completo:
Disponível
Base de dados:
LILACS
Assunto:
Tinha
/
Produtos Biológicos
/
Descoberta de Drogas
/
Antifúngicos
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. j. microbiol
Ano de publicação:
2013
Tipo de documento:
Artigo
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