Molecular characterization of Escherichia coli FtsE and FtsX.
Mol Microbiol
; 31(3): 983-93, 1999 Feb.
Article
em En
| MEDLINE
| ID: mdl-10048040
ABSTRACT
The genes ftsE and ftsX are organized in one operon together with ftsY. FtsY codes for the receptor of the signal recognition particle (SRP) that functions in targeting a subset of inner membrane proteins. We have found no indications for a structural relationship between FtsE/X and FtsY. Evidence is presented that FtsE and FtsX form a complex in the inner membrane that bears the characteristics of an ATP-binding cassette (ABC)-type transporter. FtsE is a hydrophilic nucleotide-binding protein that has a tendency to dimerize and associates with the inner membrane through an interaction with the integral membrane protein FtsX. An FtsE null mutant showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Proteínas de Ciclo Celular
/
Transportadores de Cassetes de Ligação de ATP
/
Regulador de Condutância Transmembrana em Fibrose Cística
/
Proteínas de Escherichia coli
/
Escherichia coli
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article