[Clinico-immunological comparisons in cerebral arachnoiditis]. / Kliniko-immunologicheskie sopostavleniia pri tserebral'nykh arakhnoiditakh.

ABSTRACT

106 patients with cerebral arachnoiditis diagnosed according to pneumoencephalographic and computer-tomographic findings were studied. 65 patients had clinical signs of progredient disease (lability and an increase of neurologic symptoms). In 41 patients clinical pattern was stable during several years. In the patients with a progredient course of the disease investigation of the immune status revealed that aggravation of clinical symptoms is accompanied by a decrease of a number of T-lymphocytes, an increase of the levels of immunoglobulins A and G as well as of P-proteins and of a general activity of serum interferons. Such alterations were not observed in patients with a stable course of the disease.