Enzymes that push DNA around.
Nat Struct Biol
; 6(10): 900-2, 1999 Oct.
Article
em En
| MEDLINE
| ID: mdl-10504717
ABSTRACT
DNA topoisomerases are proteins that regulate DNA topology in cells through selective cycles of DNA cleavage, manipulation, and religation. Two papers describe an ensemble of different protein conformations and nucleotide-protein complexes of Escherichia coli topoisomerase. These results lead to new insights about how this enzyme recognizes DNA and catalyzes supercoil relaxation.
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Base de dados:
MEDLINE
Assunto principal:
DNA
/
DNA Topoisomerases Tipo I
/
Escherichia coli
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article