Repeated 131I treatment of a residual ovarian teratoma containing malignant thyroid tissue.
Br J Radiol
; 72(863): 1110-3, 1999 Nov.
Article
em En
| MEDLINE
| ID: mdl-10700830
ABSTRACT
A 49-year-old woman with ovarian teratoma received 131I treatment three times for an unresectable mass containing malignant thyroid tissue after surgery. Repeated 131I treatment effectively reduced serum thyroglobulin (Tg) level and tumour uptake of 131I, despite absence of any change in size of the treated tumour. Treatment did not inhibit the increase of serum CA-125 and tumour 201Tl uptake, associated with progression of a radioresistant intratumoral hyper-perfused tissue component, detected by colour Doppler ultrasound. Serum CA-125 level and tumour 201Tl uptake were not significantly changed despite temporary increases in serum Tg level after each 131I treatment. These observations indicate the importance of diagnostic measures using combined functional imaging and tumour markers in managing this rare tumour.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Teratoma
/
Glândula Tireoide
/
Neoplasias da Glândula Tireoide
/
Coristoma
/
Compostos Radiofarmacêuticos
/
Radioisótopos do Iodo
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article