[Immunohistochemical examination oncogenic c-erb-b2, egf-r proteins and antioncogenic p53 protein in vulvar cancers HPV-16 positive and negative]. / Immunohistochemiczne oznaczanie aktywnosci proliferacyjnej oraz bialek onkogennych C-ERB-B2, EGF-R i bialka antyonkogennego p53 w rakach sromu i stanach przedrakowych sromu i pochwy HPV 16 pozytywnych i negatywnych.
Ginekol Pol
; 71(2): 63-9, 2000 Feb.
Article
em Pl
| MEDLINE
| ID: mdl-10765601
ABSTRACT
In vulvar cancers HPV 16 positive, HPV 16 negative, and vulvar and vaginal precancerous status (VIN, VAIN) immunohistochemical technik onko- and antioncogenic proteins were evaluated. The contrary correlation between HPV 16 presence and overexpression p53 were detected. It suggest the heterogenic etiology of these cancers. There was payed attention to high activity of virus replication and intensive virion production in VAIN. Nontreated vaginal lesion may make difficult to obtain a positive cervical HPV infection treatment.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
Neoplasias Vulvares
/
Genes Supressores de Tumor
/
Proteína Supressora de Tumor p53
/
Receptor ErbB-2
/
Receptores ErbB
Idioma:
Pl
Ano de publicação:
2000
Tipo de documento:
Article