Verbal learning strategies in patients with multiple sclerosis.
Cortex
; 36(2): 243-63, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10815709
ABSTRACT
Word list learning was studied in patients with a definite diagnosis of Multiple Sclerosis and in Normal Control subjects by means of the selective reminding procedure of Buschke and Fuld in two learning conditions (1) using unrelated items and (2) paired-associate items. The Multiple Sclerosis patients displayed poor learning in both conditions. To identify the functional locus of their deficit, stochastic Markov chain analyses were performed, which allowed individual measurements of encoding, automatic and intentional retrieval abilities. On both tasks, encoding on the first trial and automatic retrieval on the subsequent trials were impaired in Multiple Sclerosis patients, whereas intentional retrieval, both with and without reminding by the examiner, appeared to be preserved. As all of the impaired abilities require a normal speed of information processing, the salient learning deficit of the Multiple Sclerosis patients could be tentatively traced back to the slowing down of their mental activity.
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Base de dados:
MEDLINE
Assunto principal:
Aprendizagem Verbal
/
Esclerose Múltipla
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article