Late onset hepatitis and prolonged deterioration in hepatic function associated with nevirapine therapy.
Int J STD AIDS
; 11(5): 336-7, 2000 May.
Article
em En
| MEDLINE
| ID: mdl-10824944
ABSTRACT
The aetiology of hepatic dysfunction in patients with HIV infection is multifactorial. Re-activation of hepatitis C infection, drug toxicity, and opportunistic infections are all potential causes. Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy for the treatment of HIV infection. It is associated with a significant incidence of hepatotoxicity, usually occurring in the initial month of therapy. We report the case of a 49-year-old man who developed NVP-induced prolonged hepatotoxicity 5 months after commencing antiretroviral therapy.
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Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Fármacos Anti-HIV
/
Nevirapina
/
Doença Hepática Induzida por Substâncias e Drogas
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article