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A case of malignant transformation in thoracic vertebral hemangioma following repetitive irradiation and extraction.
Obana, Y; Tanji, K; Furuta, I; Yamazumi, T; Hashimoto, S; Kikuchi, H; Tanaka, S; Ohba, Y.
Afiliação
  • Obana Y; Department of Clinical Pathology, Kinki University School of Medicine, Osaka, Japan.
Pathol Int ; 46(1): 71-8, 1996 Jan.
Article em En | MEDLINE | ID: mdl-10846553
ABSTRACT
We report a rare case of thoracic vertebral hemangioma which developed into angiosarcoma during the course of repetitive operations and irradiation. A 44 year old female was operated on for hemangioma of the first thoracic vertebra. The diagnosis of hemangioma was confirmed histopathologically with the specimen from the first operation. The tumor developed multiple lesions later in the clinical course after the first operation, these lesions were removed in four consecutive operations and each histological diagnosis was that of hemangioma. Throughout the period of these operations, the patient was treated with steroid, and with radiotherapy simultaneously. The patient underwent the fifth operation for the recurrence of the tumor on 26 March 1990, and the histopathological diagnosis was not hemangioma but hemangiosarcoma which was considered a malignant transformation. The tumor cells immunohistochemically revealed positive staining with UEA-I, Factor-VIII, as the tumor immunohistochemically showed a vascular endothelioid nature.
Assuntos
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Base de dados: MEDLINE Assunto principal: Neoplasias da Coluna Vertebral / Vértebras Torácicas / Hemangioma / Hemangiossarcoma / Neoplasias Induzidas por Radiação Idioma: En Ano de publicação: 1996 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Neoplasias da Coluna Vertebral / Vértebras Torácicas / Hemangioma / Hemangiossarcoma / Neoplasias Induzidas por Radiação Idioma: En Ano de publicação: 1996 Tipo de documento: Article