The evolving role of dendritic cell therapy in urologic oncology.
Curr Opin Urol
; 10(4): 307-12, 2000 Jul.
Article
em En
| MEDLINE
| ID: mdl-10918968
ABSTRACT
The recognition that dendritic cells, the most potent antigen-presenting cells, play a pivotal role in the induction of antitumor immunity has reshaped the development of tumor vaccines in clinical medicine. Early clinical trials of administration of dendritic cell-based vaccines to patients with genitourinary malignancies showed low toxicity profiles, and provided evidence for immunologic and clinical responses in some patients. Although the development of dendritic cell-based vaccines is still in its infancy, the prospects of ultimately generating clinically effective cancer vaccines have become more realistic.
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Base de dados:
MEDLINE
Assunto principal:
Células Dendríticas
/
Neoplasias Urológicas
/
Vacinas Anticâncer
Idioma:
En
Ano de publicação:
2000
Tipo de documento:
Article