[Programmed cell death research in laryngeal cancer]. / Badania nad programowana smiercia komórki w raku krtani.
Otolaryngol Pol
; 54 Suppl 31: 212-5, 2000.
Article
em Pl
| MEDLINE
| ID: mdl-10974888
ABSTRACT
Apoptosis--the programmed sell death is the process of characteristic events on morphological, biochemical and molecular level which lead consequently to cell death. This process require activation of some genes i.e. p-53, mdm2 and inhibiting others i.e. bcl-2. Sixty patients with laryngeal cancer treated in ENT Department of Medical Academy of Lodz were analysed. Expression of the p-53 and bcl-2 genes' products was examined by means immunohistochemical techniques carried out on laryngeal cancer paraffin samples. Above-mentioned markers were correlated with stage of cancer progression, recurrences and metastasis of laryngeal cancer and follow-up of the patients. Initial results indicate the possible utilisation of apoptosis as prognostic factors for the patients with laryngeal cancer.
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Base de dados:
MEDLINE
Assunto principal:
Carcinoma de Células Escamosas
/
Neoplasias Laríngeas
/
Apoptose
Idioma:
Pl
Ano de publicação:
2000
Tipo de documento:
Article