Group A streptococcal genotypes from pediatric throat isolates in Rome, Italy.
J Clin Microbiol
; 39(5): 1687-90, 2001 May.
Article
em En
| MEDLINE
| ID: mdl-11325974
ABSTRACT
In a study assessing genetic diversity, 114 group A streptococcus (GAS) isolates were recovered from pediatric pharyngitis patients in Rome, Italy. These isolates comprised 22 different M protein gene (emm) sequence types, 14 of which were associated with a distinct serum opacity factor/fibronectin binding protein gene (sof) sequence type. Isolates with the same emm gene sequence type generally shared a highly conserved chromosomal macrorestriction profile. In three instances, isolates with dissimilar macrorestriction profiles had identical emm types; in each of these cases multilocus sequence typing revealed that isolates with the same emm type were clones having the same allelic profiles. Ninety-eight percent of the pharyngeal isolates had emm types previously found to be highly associated with mga locus gene patterns commonly found in pharyngeal GAS isolates.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Faringe
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Infecções Estreptocócicas
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Streptococcus pyogenes
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Faringite
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Antígenos de Bactérias
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article